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Monday, February 25
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1:00-7:00pm
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Conference and Workshop Registration Open
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PW2 Practice Based Learning in CRRT: The Science and the Art
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This workshop is designed to provide participants with the knowledge and understanding for the effective utilization of CRRT to manage critically ill patients. Session 1 on Monday focuses on the fundamentals of CRRT including the components, operational characteristics and characteristics, solute and fluid management and monitoring. Session 2 on Tuesday will utilize case based discussions and interactive sessions to illustrate the underlying concepts for application of CRRT in different situations. Delegates will participate in group exercises to apply their learning for the management of complex cases. At the end of this workshop participants will have an improved understanding of how to utilize CRRT for optimizing renal support. A quiz will be administered pre-and post- course for assessment.
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1:45-2:00
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CRRT Workshop - Day 1
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Co-chair: Jorge Cerda, MD, MS, FACP, FASN
Co-chair: Ashita Tolwani, MD
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1:45-2:00
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Opening Remarks
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Jorge Cerda, MD, MS, FACP, FASN
Ashita Tolwani, MD
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2:00-2:30
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Pre-Test
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Jorge Cerda, MD, MS, FACP, FASN
Ashita Tolwani, MD
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2:30-3:00
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PW2 Access, Membrane, Circuit
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Michael Connor, MD
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3:00-3:30
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PW2 Modality & Dose
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Jorge Cerda, MD, MS, FACP, FASN
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3:30-4:00
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PW2 Anticoagulation
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Ashita Tolwani, MD
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4:00-4:15
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Coffee Break
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4:15-4:45
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PW2 Solutions and Fluid Balance
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David Selewski, MD
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4:45-5:15
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PW2 Monitoring
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Eileen Lischer, MA, BSN, RN, CNN
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5:15-6:00
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PW2 Interactive Case Discussion
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Ashita Tolwani, MD
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6:00pm
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Adjourn
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Tuesday, February 26
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7:00am
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Conference and Workshop Registration Open
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Practice Based Learning in CRRT: The Science and the Art
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8:00-5:30
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PW2 Practice Based Learning in CRRT: The Science and the Art
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This workshop is designed to provide participants with the knowledge and understanding for the effective utilization of CRRT to manage critically ill patients. Session 1 on Monday focuses on the fundamentals of CRRT including the components, operational characteristics and characteristics, solute and fluid management and monitoring. Session 2 on Tuesday will utilize case based discussions and interactive sessions to illustrate the underlying concepts for application of CRRT in different situations. Delegates will participate in group exercises to apply their learning for the management of complex cases. At the end of this workshop participants will have an improved understanding of how to utilize CRRT for optimizing renal support. A quiz will be administered pre-and post- course for assessment.
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8:00-12:00
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CRRT Workshop - Day 2
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8:00-12:00
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Concurrent Physician and Nurse Tracks
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8:00-8:40
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PW2 PHYSICIAN - Patient Selection
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Jorge Cerda, MD, MS, FACP, FASN
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8:40-9:00
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PW2 PHYSICIAN - Drug Dosing and Adjustments
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Linda Awdishu, PharmD, MAS
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9:00-10:00
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PW2 PHYSICIAN - Correcting Acid Base Abnormalities
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David Selewski, MD
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10:00-10:20
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Coffee Break
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10:20-11:00
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PW2 PHYSICIAN - Managing Hypo and Hypernatremia
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Ashita Tolwani, MD
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11:00-11:40
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PW2 PHYSICIAN - Adjusting Nutrition
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Michael Connor, MD
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11:40-12:00
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PW2 PHYSICIAN - Achieving Survival and Recovery
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Stuart L. Goldstein, MD
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8:00-8:40
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PW2 NURSE - Orders, Charting and Monitoring
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Ian Baldwin, RN, PhD, FACCCN
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8:40-9:00
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PW2 NURSE - CRRT in the Operating Room
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Noel Oabel, BSN, RN, CNN
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9:00-10:00
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PW2 NURSE - CRRT for Pediatric Applications
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Theresa Mottes, MSN, RN,CPNP-AC,CDN
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10:00-10:20
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Coffee Break
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10:20-11:00
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PW2 NURSE - Patient Mobilization and Rehabilitation
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Eileen Lischer, MA, BSN, RN, CNN
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11:00-11:40
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PW2 NURSE - Integrating Multidisciplinary Support Team for CRRT Delivery
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Linda Awdishu, PharmD, MAS
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11:40-12:00
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PW2 NURSE - Developing Quality Measures for CRRT Delivery
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Eileen Lischer, MA, BSN, RN, CNN
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12:00-1:00
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Lunch Hosted by Conference for Workshop Participants
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1:10-4:00
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Interactive Physician and Nurse Tracks
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These sessions will have nurses, physicians and pediatric tracks. Physicians will be guided on user interfaces and the strategies for prescribing dose for solute and fluid management, adjustments in therapy parameters, recognition and management of complications. Nurses will learn how to set up for different modalities and adjust and monitor for therapy delivery based on the prescription.
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1:10-4:00
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PW2 PHYSICIAN - Circuit, Anticoagulation and Monitoring
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Noel Oabel, BSN, RN, CNN
Ashita Tolwani, MD
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1:10-4:00
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PW2 PHYSICIAN - Dose / Fluid / Documentation / Recognizing and Managing Complications
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Michael Connor, MD
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1:10-4:00
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PW2 PHYSICIAN - Prescription / Order Sets / Decision Making / Coordination of Care
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Linda Awdishu, PharmD, MAS
Jorge Cerda, MD, MS, FACP, FASN
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1:10-4:00
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PW2 PHYSICIAN - Monitoring, Alarms and Connections with Other Therapies
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Katrina Eggleston, MSN, RN
Keith Wille, MD
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1:10-4:00
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PW2 NURSE - Machine Priming, Circuit Set Up, Programing to Match Orders
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Katrina Eggleston, MSN, RN
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1:10-4:00
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PW2 NURSE - Implementing Therapy Delivery Dose Adjustments, Fluid Balance
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Eileen Lischer, MA, BSN, RN, CNN
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1:10-4:00
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PW2 NURSE - Therapy Monitoring and Troubleshooting Alarms, Therapy Discontinuation
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Noel Oabel, BSN, RN, CNN
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1:10-4:00
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PW2 NURSE - Connectology with Hybrid Systems ECMO, ECCOR, Apheresis
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Isagani Marquez, MSN, RN, QIA
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1:10-4:00
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PW2 PEDIATRIC SESSION
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David Askenazi, MD, MSPH
Stuart L. Goldstein, MD
Theresa Mottes, MSN, RN,CPNP-AC,CDN
David Selewski, MD
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Modality Selection, Circuit Modifications, Therapy Dosing, Monitoring, Adjustments for Targeted Interventions
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4:00-4:15
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Coffee Break
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4:15-4:55
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PW2 Interactive Clinical Case (Decision Making)
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Ashita Tolwani, MD
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5:00-5:30
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PW2 Post Course Test and Wrap-up
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Jorge Cerda, MD, MS, FACP, FASN
Ashita Tolwani, MD
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5:30pm
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Adjourn
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Pre-Conference AKI Symposium
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7:55-5:30
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PW1 Changing Paradigms in Acute Kidney Injury:
From Mechanisms to Management
sponsored by:
The UAB-UCSD O'Brien Core Center for
Kidney Injury Research
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Acute Kidney Injury is a rapidly evolving area where several advances have been made in understanding the mechanisms and pathways of AKI and its effects on other organs. Recent identification of biomarkers has provided new tools and techniques to characterize this disorder. This pre-course workshop will provide a comprehensive review of the most recent developments in the field and describe emerging knowledge from basic and translational research. Results from clinical trials will be discussed to define the best strategies for effective management of patients and define the criteria for future studies.
CRRT Conference registration is not required to attend this symposium, separate registration is available.
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7:55-8:00
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Opening Remarks
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Ravindra L. Mehta, MBBS, MD, DM, FACP
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8:00-8:20
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AKI Symposium - Plenary 1
Molecules, Mechanisms and Targets
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Co-chair: Anupam Agarwal, MD
Co-chair: Bruce A. Molitoris, MD
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8:00-8:20
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PW1 TGF-b in the AKI to CKD Transition
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Leslie Gewin, MD
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8:20-8:40
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PW1 Pannexins in Acute Kidney Injury
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Mark D. Okusa, MD
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8:40-9:00
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PW1 Single Cell Transcriptomics in AKI and CKD
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Ben Humphreys, MD, PhD
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9:00-9:20
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PW1 Regulatory B Cells and Natural IgM in AKI
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Peter Lobo, MD
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9:20-9:40
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PW1 The Kidney is Out of Breath in AKI
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Can Ince, PhD
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9:40-10:00
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Discussion
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10:00-10:15
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Coffee Break
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10:15-10:35
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AKI Symposium - Plenary 2
Harmonizing Human and Animal AKI: Results from ADQI 13
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Co-chair: Paul Sanders, MD
Co-chair: Volker Vallon, MD
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10:15-10:35
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PW1 Molecular Characterization of the Transition from AKI to CKD
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Andrew McMahon, PhD
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10:35-10:55
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PW1 Impact of Metabolism on Surviving Sepsis: Implications for Sepsis-induced AKI
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Sarah Huen, MD, PhD
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10:55-11:15
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PW1 HDAC Inhibition for Prevention of Fibrosis Following Sepsis-induced AKI
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John A. Kellum, MD
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11:15-11:35
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PW1 Epigenetic Regulation in AKI
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Zheng Dong, PhD
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11:35-11:55
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PW1 Renin-Angiotensin-Aldosterone System: Good for the Kidney
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Matthieu LeGrand, Pr
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11:55-12:15
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Discussion
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12:15-1:15
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Lunch Hosted by Conference for Workshop Participants
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1:15-1:35
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AKI Symposium - Plenary 3
Bench to Bedside: Translating Discoveries to Clinical Care
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Co-chair: Kathleen Liu, MD, PhD, MAS
Co-chair: Patrick T. Murray, Prof
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1:15-1:35
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PW1 Successfully Testing AKI Therapies in CKD Models
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Bruce A. Molitoris, MD
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1:35-1:55
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PW1 Metabolic Stress in AKI: From Mouse to Man
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Samir Parikh, MD
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1:55-2:15
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PW1 Tubular Health Characterization in AKI
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Etienne Macedo, MD, PhD, FASN
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2:15-2:35
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PW1 AKI in Kidney Transplants: New Insights
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Roslyn Mannon, Dr.
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2:35-2:55
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PW1 Renal Injury During Preclampsia: Role of Extracellular Vesicles
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Vincenzo Cantaluppi, MD
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2:55-3:15
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Discussion
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3:15-3:30
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Coffee Break
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3:30-3:50
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AKI Symposium - Plenary 4
Controversies in AKI
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Co-chair: Stuart L. Goldstein, MD
Co-chair: Claudio Ronco, MD
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3:30-3:50
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PW1 AKI following Cardiac Surgery: A Clinical Model
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Frederic Billings, MD, MSc
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3:50-4:10
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PW1 Renal Immune Surveillance in AKI
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Daniel Muruve, MD
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4:10-4:30
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PW1 Remote Ischemic Preconditioning: Fact or Fantasy?
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Alex Zarbock, MD
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4:30-4:50
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PW1 Targeting AKI Using Biomarker Combinations
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Rajit Basu, MD MS FCCM
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4:50-5:10
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PW1 Phenotyping Acute Kidney Disease - ATN vs. AIN?
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Chirag Parikh, MD, PhD
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5:10-5:30
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Discussion
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5:30pm
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AKI Workshop Adjourns
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5:30-7:30pm
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Reception and Poster Review
For All Conference Attendees
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Kent Doi, MD
Can Ince, PhD
Magdalena Madero, MD
Bruce A. Molitoris, MD
Patrick T. Murray, Prof
Ron Wald, MD
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ORAL POSTER SESSIONS:
BASIC AND APPLIED RESEARCH IN AKI
Ince, Molitoris (Moderators)
CLINICAL RESEARCH IN AKI - I
Murray, Doi (Moderators)
EPI AND OUTCOMES - I
Madero, Wald (Moderators)
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Wednesday, Morning February 27
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7:00am
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Conference Registration Open
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7:00-8:15
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Meet the Experts (elective event)
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7:00-8:15
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ME1 MEET THE EXPERT
How I Treat Septic Shock
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Kathleen Liu, MD, PhD, MAS
John Louis Vincent, MD PhD
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7:00-8:15
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ME2 MEET THE EXPERT
How do I Manage the Fluid Overloaded Patient?
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Sean Bagshaw, MD, MSc, FRCPC
Stuart L. Goldstein, MD
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The Breakfast Symposia listed below are hosted by Conference (RSVP Required)
Selection made during registration
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7:00-8:15
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Breakfast Symposia
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7:00-8:15
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Breakfast Symposium A
Drug Induced Kidney Injury in the Critically Ill Patient
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Linda Awdishu, PharmD, MAS
Melanie Joy, PharmD, PhD
Patrick T. Murray, Prof
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CME Available
Patients in the ICU are exposed to several different drugs to treat the underlying disease and support organ function. This symposium will highlight the practical aspects of drug handling in critically ill patients and illustrate how patients should be evaluated for risk for drug induced kidney injury, how should they be dosed and monitored for adjustments in drug dosing.
Awdishu (Moderator), Murray and Joy (Discussants)
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7:00-8:15
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Breakfast Symposium B
Therapeutic Challenges in AKI and CKD: Managing Hypo and Hyperkalemia
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Andrew Lewington, MD
Qi Qian, MD
Ron Wald, MD
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CME Available
This symposium will cover the pathophysiology and management of hypo and hyperkalemia in critically ill patients using illustrative cases. What are the newer therapeutic drugs available and how should they be used When and how should RRT be used in these situations?
Wald (Moderator), Qian and Lewington (Discussants)
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SESSION I: PATIENT CHARACTERISTICS
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8:20-8:30
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Plenary 1 MINI-SYMPOSIA
Organ Dysfunction in the Critically Ill Patient: Emerging Concepts
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Co-chair: Noel Gibney, MB FRCP(C)
Co-chair: Kathleen Liu, MD, PhD, MAS
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8:20-8:30
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Opening Remarks
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Ravindra L. Mehta, MBBS, MD, DM, FACP
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8:30-8:45
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Hemodynamics of the Septic Kidney
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Matthieu LeGrand, Pr
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8:45-9:00
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The Kidney in Heart Failure: Victim or Culprit?
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Salvatore diSomma, MD
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9:00-9:15
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The Pathogenesis of Vascular Barrier Dysfunction
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Can Ince, PhD
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9:15-9:30
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Vasoplegic Shock: Definitions and Pathophysiology
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Lui Forni, MD
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9:30-9:45
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Hepatorenal Syndrome: Does it Exist?
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Mitra Nadim, MD, FASN
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9:45-10:00
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Metabolic Acidosis in the Critically Ill Patient
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Ron Wald, MD
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10:00-10:30
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SPECIAL LECTURE
New Advances in the Treatment of Sepsis
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John Louis Vincent, MD PhD
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10:30-11:00
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Coffee Break and Faculty Picture
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STANDARD WORKSHOPS
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Open to all participants and applicable to physicians, nurses and allied personnel.
Workshop Codes: C= Core workshop, I = Intermediate, A = Advanced, N= Nurses, AP = of interest to nurses and allied personnel
Workshops presented in a series are marked with a "1" for a primary workshop discussion in this area and "2" for a more complex or advanced discussion in this area. Please note that the series workshops 1 and 2 can be either taken subsequently (following each other) or they can each be taken independently (e.g. workshop 1 can be taken without taking workshop 2 and vice versa).
FOCUSED SYMPOSIA
These focused symposia are offered in 3 categories (3 sessions in each category) on Wednesday and Thursday and run concurrrently with the Standard Workshops. Sessions can be taken as a group (3) or independently. Selections made during online registration process.
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11:00-12:30
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Standard Workshop Group 1
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11:00-12:30
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A01 Who Should Get a Kidney Biomarker Assessment?
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Rajit Basu, MD MS FCCM
Jay Koyner, MD
Alex Zarbock, MD
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Several biomarkers are now available to assess kidney function and damage. Which patients should get these assessments and how should these be applied will be discussed in this case based workshop.
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11:00-12:30
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B02 Optimizing the CRRT Circuit (Access, Anticoagulation and Assessments)
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David Askenazi, MD, MSPH
Ian Baldwin, RN, PhD, FACCCN
Ashita Tolwani, MD
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Keeping the CRRT circuit open and working efficaciously requires a consideration of several factors including the access, membrane and anticoagulation. This workshop will highlight the best practices for maintaining and monitoring the circuit.
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11:00-12:30
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C03 Assessment of Fluid Responsiveness, Hemodynamic Monitoring and Targets
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Can Ince, PhD
David Selewski, MD
John Louis Vincent, MD PhD
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Determining which patient needs fluids, what type and how much are key questions to be addressed in this workshop which will cover the principles and strategies for volume assessment, hemodynamic and microcirculatory monitoring in critically ill patients.
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11:00-12:30
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D04 Managing Patients with Combined Kidney and Liver Failure
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Akash Deep, Dr
Mitra Nadim, MD, FASN
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Patients with combined liver and kidney failure are difficult to manage. This workshop will discuss the pathophysiology and illustrate best approaches for differential diagnosis and management of these patients.
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11:00-12:30
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E05 Establishing and Maintaining Core Competencies for Nurses for CRRT
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Eileen Lischer, MA, BSN, RN, CNN
Theresa Mottes, MSN, RN,CPNP-AC,CDN
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NURSES TRACK (E Series)
Competency based education and training are a key feature to establish an efficient CRRT program. This workshop will discuss the core curriculum for nursing education, training and skills assessment for performing CRRT and hybrid techniques.
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11:00-12:30
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F06 Principles, Applications and Practical Issues of Plasma Exchange
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Isagani Marquez, MSN, RN, QIA
Eisei Noiri, MD, PhD, FASN
Amber Sanchez, MD
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Plasma exchange (PE) is increasingly utilized in the ICU with CRRT and other extracorporeal techniques.
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12:30-2:00
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Lunch Symposia Hosted by Conference (RSVP Required)
Selection made during registration
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12:30-2:00
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Lunch Symposia
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12:30-2:00
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Lunch Symposium W1
Citrate Anticoagulation for CRRT: Techniques and Results
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Stuart L. Goldstein, MD
Matthieu LeGrand, Pr
Marlies Ostermann, MD
Ashita Tolwani, MD
David M. Ward, MD, FRCP
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CME Available
Regional citrate anticoagulation (RCA) is increasingly utilized for CRRT and many techniques are now used. Advances in technology have enabled automated citrate anticoagulation. However, concerns remain about its ease of use and application in patients with liver failure and reduced tissue perfusion. This symposium will discuss the best approaches for utilizing RCA for CRRT.
Moderators: Goldstein and Ward
The Why, How and What of Citrate Anticoagulation - Tolwani
Automated Citrate Delivery: Does it Work? - LeGrand
Metabolic Consequences of Citrate - Ostermann
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12:30-2:00
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Lunch Symposium W2
Phenotypes of Shock: Which Fluid, Which Vasopressor?
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Lui Forni, MD
Can Ince, PhD
Kathleen Liu, MD, PhD, MAS
John Prowle, MA MSc MD FRCP FFICM
John Louis Vincent, MD PhD
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CME Available
There is increasing evidence that different patient respond differently to fluids and vasopressor management for shock. This symposium will discuss how best we may identify phenotypes to personalize fluid type (colloids and crystalloids and blood products) and volume and vasopressor management in shock patients to improve outcomes.
Moderators: Prowle and Vincent
Fluid Responsiveness Phenotypes: Lessons from ARDS Trials - Liu
Shock States Differ in Response to Vasopressors - Forni
Is the Microcirculation the Appropriate Target for Fluids and Vasopressors? - Ince
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12:30-2:00
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Lunch Symposium W3
Extracorporeal Organ Support (ECOS) for Multi Organ Failure and Sepsis
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Akash Deep, Dr
Patrick M. Honore, MD, PhD
John A. Kellum, MD
Eisei Noiri, MD, PhD, FASN
Claudio Ronco, MD
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CME Available
Membrane characteristics have evolved to enhance the removal of solutes of different sizes and configurations providing novel methods for blood purification. This symposium will cover the recent advances in this field and discuss how best to utilize these techniques.
Moderators: Honore and Deep
Advances in Membrane Technology - Ronco
Sorbent Based Toxin Removal - Kellum
Apheresis Techniques: Do They Have a Role? - Noiri
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12:30-2:00
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Lunch Symposium W4
Quality Metrics in AKI and CRRT: Establishing Benchmarks
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Sean Bagshaw, MD, MSc, FRCPC
Jorge Cerda, MD, MS, FACP, FASN
Kianoush Kashani, MD
Theresa Mottes, MSN, RN,CPNP-AC,CDN
Nick Selby, MD
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CME Available
AKI is a complex disease that requires multidisciplinary interventions however there are currently limited measures to assess quality of care for AKI management. This symposium will discuss the recommendations from the ADQI 22 meeting and highlight some of the practical issues for implementing a quality program for AKI and CRRT
Moderators: Cerda and Selby
Quality of Care in AKI: What are the Consensus Recommendation from ADQI? - Kashani
Implementing a Quality Program for AKI in your ICU: Lessons from Pediatrics - Mottes
What Benchmarks Should We Use for Measuring Quality in CRRT? - Bagshaw
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12:30-2:00
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Lunch Symposium I1
Additional Industry Session Offered (Non-CME)
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TBA
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Wednesday, Afternoon, February 27
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2:00-3:30
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Standard Workshop Group 2
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2:00-3:30
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A07 Can Kidney Biomarkers Help Timely Interventions and Prognostication?
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Salvatore diSomma, MD
Jay Koyner, MD
Patrick T. Murray, Prof
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Clinicians need to determine when a specific intervention is needed and what is the likelihood of modifying the disease course. This workshop will discuss how novel renal biomarkers can be leveraged to guide specific interventions in patients with AKI in different settings.
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2:00-3:30
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B08 Can We Achieve Precision Solute Control with CRRT?
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Rolando Claure-Del Granado, MD, FASN
Claudio Ronco, MD
David Selewski, MD
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CRRT techniques have evolved with availability of new technology to customize dialysis delivery. This interactive case based workshop will discuss how to apply the technology for dose adjustments, monitoring for adequacy, modality selection and transitions in CRRT.
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2:00-3:30
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C09 Starting, Transitioning and Stopping RRT for AKI: Science and Art
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Etienne Macedo, MD, PhD, FASN
Ravindra L. Mehta, MBBS, MD, DM, FACP
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One of the most vexing issues for clinicians is determining when to initiate RRT in critically ill patients, when and how to transition modalities and when it can be stopped. This workshop will use case studies to explore various approaches and establish the principles for clinical decisions for renal support.
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2:00-3:30
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D10 Managing Patients with Sepsis: Can We Modify the Course with Extracorporeal Organ Support (ECOS)
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Rajit Basu, MD MS FCCM
Patrick M. Honore, MD, PhD
Matthieu LeGrand, Pr
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Septic patients often require ECOS to allow time for recovery. This workshop covers the rationale and strategies for the practical application of extracorporeal support techniques for sepsis. Case studies will be utilized to delineate different options.
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2:00-3:30
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E11 Infection Control for Extracorporeal Organ Support (ECOS) Techniques
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Saima Aslam, MD
Eileen Lischer, MA, BSN, RN, CNN
Theresa Mottes, MSN, RN,CPNP-AC,CDN
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NURSES TRACK (E Series)
Infection Control for Extracorporeal Organ Support (ECOS) TechniquesPatients undergoing ECOS are at a high risk for infections and require a concerted effort for surveillance, primary prevention and early interventions. This case based workshop will discuss the current guidelines for infection control for patients on ECOS.
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2:00-3:30
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F12 Pediatric and Adult AKI and CRRT: Collaborations Across the Age Spectrum
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David Askenazi, MD, MSPH
Stuart L. Goldstein, MD
Claudio Ronco, MD
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Although pediatric and adult patients have similar indications for CRRT the therapy application varies considerably. This workshop will highlight the best practices for CRRT application across the age spectrum.
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3:30-4:00
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Coffee Break
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4:00-4:15
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Plenary 2 MINI-SYMPOSIA
Acute Kidney Injury (AKI): Pathophysiology
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Co-chair: Jay Koyner, MD
Co-chair: Bruce A. Molitoris, MD
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4:00-4:15
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Is Atypical HUS Masquerading as Sepsis-induced AKI?
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John A. Kellum, MD
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4:15-4:30
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Extracellular Vesicles in AKI: What do They Tell Us?
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Vincenzo Cantaluppi, MD
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4:30-4:45
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AKI in Neonates: Lessons Learnt
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David Askenazi, MD, MSPH
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4:45-5:00
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Urinary Sediments in AKI Detection and Differentiation
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Li Yang, MD
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5:00-5:15
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Role of Repair Biomarkers in AKI
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Chirag Parikh, MD, PhD
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5:15-5:30
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Mechanisms of Drug Induced AKI
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Melanie Joy, PharmD, PhD
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5:30-6:00
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SPECIAL LECTURE
Informatics in Disease Management: What Will the Future Hold?
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Mike Hogarth, MD
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6:00
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Adjourn
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6:00-8:00
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6:00-8:00
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Exhibit Reception and Poster Session
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David Askenazi, MD, MSPH
Emmanuel Burdmann, MD, PhD
Kathleen Liu, MD, PhD, MAS
Eisei Noiri, MD, PhD, FASN
Nick Selby, MD
David M. Ward, MD, FRCP
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ORAL POSTER SESSIONS:
CLINICAL RESEARCH IN AKI AND NAP
Askenazi, Selby (Moderators)
EPI AND OUTCOMES II
Burdmann, Liu (Moderators)
NEW TECHNOLOGY RRT RESEARCH
Noiri, Ward (Moderators)
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Thursday, Morning, February 28
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7:00am-4:30pm
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Registration Open
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7:00-8:00
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Coffee Served
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7:00-8:15
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ME3 MEET THE EXPERT
How I Use AKI Biomarkers in My Practice
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Claudio Ronco, MD
Alex Zarbock, MD
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7:00-8:15
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ME4 MEET THE EXPERT
What Blood Pressure do I Target in My ICU Patients?
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John A. Kellum, MD
Patrick T. Murray, Prof
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Breakfast Symposia listed below are hosted by Conference (RSVP Required)
Selection made during registration
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7:00-8:15
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Breakfast Symposia
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7:00-8:15
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Breakfast Symposium C
Innovations in Caring for Patients with Dysnatremias
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Kianoush Kashani, MD
Andrew Lewington, MD
Qi Qian, MD
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CME Available
Dysnatremias are commonly encountered in ICU patients and are often difficult to manage. This symposium will cover the pathophysiology of hypo and hypernatremia and discuss the practical issues for management of these disorders with novel agents and describe how RRT can be used for severe disorders.e
Kashani (Moderator), Qian and Lewington (Discussants)
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7:00-8:15
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Breakfast Symposium D
Managing AKI in the Patient with Cancer
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Melanie Joy, PharmD, PhD
Marlies Ostermann, MD
Mitchell H. Rosner, MD
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CME Available
The number of anticancer drugs are increasingly expanding and commonly cause kidney injury. This symposium will discuss how to prevent drug nephrotoxicity, adjust doses of anticancer medicines and manage patients who develop AKI in the setting cancer therapy.
Ostermann (Moderator), Rosner and Joy (Discussants)
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8:15-9:45
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Standard Workshop Group 3
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8:15-9:45
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A13 Preventing AKI: From Surveillance to Intervention
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Rajit Basu, MD MS FCCM
Kianoush Kashani, MD
Andrew Lewington, MD
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This workshop will describe the current status of methods to identify patients at high risk for AKI and techniques for electronic surveillance. Strategies and tools for preventing AKI in different settings will be discussed.
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8:15-9:45
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B14 Personalized Fluid Management with CRRT
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Ravindra L. Mehta, MBBS, MD, DM, FACP
John Prowle, MA MSc MD FRCP FFICM
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Achieving fluid balance and maintaining plasma composition is key for effective CRRT. This workshop will use case studies to discuss strategies for fluid management in CRRT to achieve patient driven outcomes for fluid, electrolyte and acid base balance.
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8:15-9:45
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C15 Drug Dosing in RRT: Management Strategies
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Stuart L. Goldstein, MD
Melanie Joy, PharmD, PhD
Patrick T. Murray, Prof
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Patients receiving RRT in the ICU are in multiple drugs which are affected by the procedures and require adjustments to ensure an adequate exposure. This workshops will focus on the principles for appropriate drug dosing and adjustments in patients on RRT.
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8:15-9:45
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D16 Managing the Heart Failure Patient with Worsening Renal Function (WRF)
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Salvatore diSomma, MD
Peter A. McCullough, MD, MPH
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Patients with advanced heart failure often develop WRF. It is often difficult to determine which patients can be managed with drug therapy vs requiring RRT. This workshop will describe the practical application and results of different methods to treat heart failure and cardio-renal syndrome including ultrafiltration techniques.
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8:15-9:45
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E17 Intraoperative RRT: Strategies for Success
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Linda Awdishu, PharmD, MAS
Sean Bagshaw, MD, MSc, FRCPC
Eileen Lischer, MA, BSN, RN, CNN
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NURSES TRACK (E Series)
When is RRT needed in the operating room? Practical issues in setting up and implementing a program will be discussed using a case based approach.
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8:15-9:45
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F18 Pediatric AKI and CRRT: How do I Care for My Patient and My Program?
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Theresa Mottes, MSN, RN,CPNP-AC,CDN
David Selewski, MD
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Review and discussion of best practices to develop your pediatric AKI and CRRT program, identify and treat your young patients with AKI, and to assure delivery of high-quality care in the pediatric setting.
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9:45-10:15
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Coffee Break
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SESSION II: CONTROVERSIES IN CRITICAL CARE NEPHROLOGY
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10:15-10:30
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Plenary 3 MINI-SYMPOSIA
Challenges in ICU Management
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Co-chair: Rajit Basu, MD MS FCCM
Co-chair: John Prowle, MA MSc MD FRCP FFICM
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10:15-10:30
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Early Resuscitation of the Unstable Patient: When and How?
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John Louis Vincent, MD PhD
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10:30-10:45
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Should Saline be Out of the ICU?
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Matthieu LeGrand, Pr
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10:45-11:00
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Fluid Overload - Iatrogenesis Imperfecta
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David Selewski, MD
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11:00-11:15
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Mobilization in the ICU: Fact or Fantasy?
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Noel Gibney, MB FRCP(C)
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11:15-11:30
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Deresuscitation in Critically Ill Patients with AKI
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Sean Bagshaw, MD, MSc, FRCPC
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11:30-11:45
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Novel Bacteriophage Therapy for Critical Infections
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Saima Aslam, MD
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11:45-12:15
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SPECIAL LECTURE
Translating Mechanisms to Management Award
Challenges and Opportunities in AKI Diagnositics
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John A. Kellum, MD
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12:15-12:30
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Top Abstract Awards
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12:30-2:00
|
Lunch Symposia Hosted by Conference (RSVP Required)
Selection made during registration
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12:30-2:00
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Lunch Symposia
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12:30-2:00
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Lunch Symposium T1
Precision Medicine for All: Challenges and Opportunities for Critical Illness
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Melanie Joy, PharmD, PhD
John A. Kellum, MD
Patrick T. Murray, Prof
Chirag Parikh, MD, PhD
John Louis Vincent, MD PhD
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CME Available
Precision medicine aims to lead to personalized treatment and improved outcomes. However its application in AKI and critical care faces many challenges including patient characterization and specific targets for timely interventions. This session will discuss approaches to address these challenges and provide a framework for achieving personalized care.
Moderators: Joy and Murray
Can We be Precise for Critical Care? - Kellum
Endophenotypes in AKI: Path to Precision Interventions? - Parikh
Should We Focus on Personalized Medicine Rather than Precision? - Vincent
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12:30-2:00
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Lunch Symposium T2
Hydration and Kidney Health
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Emmanuel Burdmann, MD, PhD
Rajasekara Chakravarthi, MD, DNB (Nephrology)
Magdalena Madero, MD
Qi Qian, MD
Vincent Wu, MD, PhD
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CME Available
Fluid administration is the commonest approach to manage patients with perceived renal dysfunction. However is this the correct approach for all patients? This symposium will review the evidence for our current strategy and provide guidance on best practices to manage patients with fluids to improve kidney function.
Moderators: Wu and Chakaravarthi
Fluid Therapy for AKI: When, How and What? - Qian
AKI and Exercise: The Good, the Bad and the Ugly - Burdmann
Vasopressin and Kidney Injury - Madero
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12:30-2:00
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Lunch Symposium T3
Imaging Techniques in Critically Ill Patients with Kidney Disease
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Mitra Nadim, MD, FASN
Chaan Ng, MD PhD
Mitchell H. Rosner, MD
Nick Selby, MD
Nattachai Srisawat, MD
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CME Available
Patients with kidney dysfunction evoke concern whenever an imaging study is needed. This session will deliberate some of the common issues for evaluating patients with different imaging techniques.
Moderators: Nadim and Sirsawat
Should We Avoid Radiocontrast Enhanced Imaging? - Rosner
What is the Role of MRI? - Selby
Imaging Considerations in High Risk Oncology Patients? - Ng
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12:30-2:00
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Lunch Symposium T4
Targeting Renal Recovery from Critical Illness
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Rajit Basu, MD MS FCCM
Jorge Cerda, MD, MS, FACP, FASN
Jay Koyner, MD
John Prowle, MA MSc MD FRCP FFICM
Ron Wald, MD
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CME Available
Non-recovery from AKi is associated with a high mortality, cardiovascular disease and increased resource utilization. There is great need to target interventions to improve recovery from AKI. This symposium will discuss the key issues in this area.
Moderators: Basu and Cerda
How Should We Monitor for Renal Recovery? - Prowle
Do We Have Biomarkers that Predict Recovery? - Koyner
Caring for the AKI Survivor: What is Required? - Wald
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12:30-2:00
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Lunch Symposium I2
Additional Industry Session Offered (Non-CME)
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Details
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SESSION III: EMERGING CONCEPTS IN AKI AND RRT
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2:00-2:15
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Plenary 4 MINI SYMPOSIA
Novel Strategies in AKI Management
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Co-chair: Andrew Lewington, MD
Co-chair: Ron Wald, MD
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2:00-2:15
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Cardiorenal Syndrome: What Have We Learned?
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Peter A. McCullough, MD, MPH
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2:15-2:30
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Vitamin D Regulation in AKI: Opportunity to Intervene?
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Marlies Ostermann, MD
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2:30-2:45
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Why are Some People Resistant to AKI?
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John A. Kellum, MD
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2:45-3:00
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Does AKI Always Lead to CKD and Premature Death?
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Chirag Parikh, MD, PhD
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3:00-3:15
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Renal Functional Reserve: A Target for Intervention?
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Claudio Ronco, MD
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3:15-3:30
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Clinical Prediction Rules: Can We Improve?
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Lui Forni, MD
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3:30-3:45
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Subphenotypes for AKI: Where are We Headed?
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Ravindra L. Mehta, MBBS, MD, DM, FACP
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3:45-4:15
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Coffee Break
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4:15-4:30
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Plenary 5 MINI SYMPOSIA
Challenges and Controversies in Renal Support and CRRT
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Co-chair: David Selewski, MD
Co-chair: Ashita Tolwani, MD
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4:15-4:30
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Volume First in the Management of Patients with AKI Receiving RRT?
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Ron Wald, MD
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4:30-4:45
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Calcium Containing Solutions for Citrate CRRT: Does it Work?
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Ravindra L. Mehta, MBBS, MD, DM, FACP
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4:45-5:00
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Antibiotic Dosing in Patients on RRT: Are We Doing it Right?
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Linda Awdishu, PharmD, MAS
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5:00-5:30
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SPECIAL LECTURE
Quality of Care for AKI: Highlights from ADQI 22
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Kianoush Kashani, MD
Mitchell H. Rosner, MD
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5:30-6:00
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VIEWPOINTS
Biomarker Based Management of AKI: Are We Ready
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Matthieu LeGrand, Pr
Chirag Parikh, MD, PhD
Claudio Ronco, MD
Alex Zarbock, MD
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Moderator - Ronco
No We Don't Have Enough Data - LeGrand
We are Not Sure - Parikh
Yes Absolutely - Zarbock
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6:00
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Adjourn
Free Evening
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Friday, Morning, March 1
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7:00am-1:00pm
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Conference Registration Open
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7:30-8:00
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Coffee Served
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6:45-8:00
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Meet the Experts
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6:45-8:00
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ME5 MEET THE EXPERT
When do I Start RRT in My ICU
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Marlies Ostermann, MD
Claudio Ronco, MD
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6:45-8:00
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ME6 MEET THE EXPERT
How do I Manage Oliguria
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Lui Forni, MD
Matthieu LeGrand, Pr
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6:45-8:00
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Breakfast Symposia
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6:45-8:00
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I3. Additional Industry Breakfast Session (Non-CME)
I4. Additional Industry Breakfast Session (Non-CME)
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Details
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SESSION IV: IMPROVING OUTCOMES IN AKI
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8:00-8:15
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Plenary 6 MINI SYMPOSIA
Global Burden of AKI
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Co-chair: Eisei Noiri, MD, PhD, FASN
Co-chair: Marlies Ostermann, MD
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8:00-8:15
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Pediatric AKI Around the World: A Neglected Disease?
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Jorge Cerda, MD, MS, FACP, FASN
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8:15-8:30
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Neglected Tropical Diseases and AKI: An Escalating Problem
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Emmanuel Burdmann, MD, PhD
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8:30-8:45
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Long-term Prognosis and Medical Treatment After AKI
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Vincent Wu, MD, PhD
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8:45-9:00
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Using Mobile Health for Early AKI Recognition
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Rolando Claure-Del Granado, MD, FASN
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9:00-9:15
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AKI in Southeast Asia: Patterns of Care
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Nattachai Srisawat, MD
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9:15-9:30
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Disaster Management for Kidney Patients: What Have We Learnt?
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Noel Gibney, MB FRCP(C)
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9:30-9:45
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Renal Replacement in Liver Failure: Bridge to Liver Transplant or Liver Regeneration
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Akash Deep, Dr
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9:45-10:00
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Drug-induced AKI: Improving Diagnostic and Preventive Strategies in China
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Li Yang, MD
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10:00-10:15
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Preventing AKI in Resource Poor Regions: The Role of Clean Water
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Etienne Macedo, MD, PhD, FASN
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10:15-10:30
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Clinical-pathological Correlations in AKI
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Rajasekara Chakravarthi, MD, DNB (Nephrology)
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10:30-11:00
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Coffee Break
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SESSION V: FUTURE TRENDS IN CRRT AND CRITICAL CARE
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11:00-12:30
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Plenary 7 MINI SYMPOSIA
Emerging Strategies in AKI and Extracorporeal Support
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Co-chair: Jorge Cerda, MD, MS, FACP, FASN
Co-chair: Vincent Wu, MD, PhD
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11:00-12:30
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Update from Ongoing and Late Breaking Trials
(12 minutes each)
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Patrick M. Honore, MD, PhD
Kianoush Kashani, MD
John A. Kellum, MD
Kathleen Liu, MD, PhD, MAS
Etienne Macedo, MD, PhD, FASN
Nick Selby, MD
Nattachai Srisawat, MD
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1. Reducing Intradialytic Hypotension: Colloids vs Crystalloids? - Macedo
2. IV Fluid Resuscitation: The VOLUME-CHASER Study - Kashani
3. ARDS Trials: An Update - Liu
4. Early vs Standard Initiation of RRT: The FST Trial - Sirsawat
5. Complex Interventions for AKI - Lessons from the Tackling AKI Study - Selby
6. Sorbent Based Therapies for MOF - Honore
7. Predicting AKI Recovery: The RUBY Trial - Kellum
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12:30-12:55
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Critical Care Nephrology: Literature Review
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Noel Gibney, MB FRCP(C)
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12:55-1:00
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Closing Remarks
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Ravindra L. Mehta, MBBS, MD, DM, FACP
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1:00
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Conference Adjourns
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