Search © 2007-2010 CRRT Inc. CRRT 2010 Conference - Program and Workshops Complete CRRT Brochure PDF (988K) Tuesday, February 23 5:00-8:00pm Registration for Wednesday's Hands-On Workshop Pre-Conference AKI Workshop Wednesday, February 24 7:00am Registration for All Wednesday's Hands-On Workshop 8:00-6:00 PW1 Changing Paradigms in Acute Kidney Injury: From Mechanisms to Management Conference registration is not required to attend this elective workshop. Acute Kidney Injury is a rapidly evolving area where several advances have been made in understanding the mechanisms and pathways of AKI and its effects on other organs. Recent identification of biomarkers has provided new tools and techniques to characterize this disorder, This pre-course workshop will provide a comprehensive review of the most recent developments in the field and describe emerging knowledge from basic and translational research. Results from clinical trials will be discussed to define the best strategies for effective management of patients and define the criteria for future studies. 8:00-8:05 Opening Remarks Ravindra L. Mehta, MBBS, MD, DM, FACP, AKI Workshop - Plenary 1 8:00-10:15 Co-chair: Roland C. Blantz, MD Co-chair: H. David Humes, MD 8:05-10:15 Molecules, Mechanisms and Targets 8:05-8:25 Sepsis Induced AKI: Mechanisms and Targets for Intervention Martin Matejovic, MD 8:25-8:45 Visualizing and Targeting Endothelial Dysfunction in AKI Bruce A. Molitoris, MD 8:45-9:05 Innate Immunity: A New Therapeutic Target for AKI? Mark D. Okusa, MD 9:05-9:25 Heme Oxygenase-1 and AKI: From Molecular Mechanisms to Therapeutic Opportunities Anupam Agarwal, MD 9:25-9:45 Repair and Regeneration Mechanisms Hamid Rabb, MD 9:45-10:15 Panel Discussion 10:15-10:30 Coffee Break AKI Workshop - Plenary 2 10:30 -12:45 Co-chair: Patrick T. Murray, MD Co-chair: Paul Palevsky, MD 10:30 -12:45 Trials, Tribulations and Outcomes 10:30-10:50 Validation of Diagnostic and Staging Criteria John A. Kellum, MD 10:50-11:10 Prevention Trials in AKI Peter A. McCullough, MD, MPH 11:10-11:30 Dose Trials: Lessons Learned and Applied Paul Palevsky, MD 11:30-11:50 Cardiac Surgery and AKI Trials Andrew D. Shaw, MD FRCA FCCM 11:50-12:10 Device Studies - Challenges and Lessons H. David Humes, MD 12:10-12:30 Determining Long Term Outcomes from AKI Paul Eggers, PhD 12:30-12:45 Panel Discussion 12:45-1:30 Lunch Hosted by Conference for Workshop Participants AKI Workshop - Plenary 3 1:30-3:15 Co-chair: Prasad Devarajan, MD Co-chair: Andre A. Kaplan, MD 1:30-3:15 Tools and Techniques to Characterize AKI 1:30-1:45 Estimating GFR in AKI Josée Bouchard, MD 1:45-2:00 Genomic Tools for AKI Daniel O’Connor, MD 2:00-2:15 Biomarker Development and Validation Cormac Kilty, PhD 2:15-2:30 AKI Biomarkers: Distinguishing Real Injury from Functional Change Prasad Devarajan, MD 2:30-2:45 Biomarkers In AKI: Clinical Performance Patrick T. Murray, MD 2:45-3:05 Monitoring Kidney Safety in Early Drug Development Frank Dieterle, PhD 3:05-3:15 Panel Discussion 3:15-3:30 Coffee Break AKI Workshop - Plenary 4 3:30-6:00 Co-chair: Michael Joannidis, MD Co-chair: David Warnock, MD 3:30-6:00 Trial Designs and Outcomes for Clinical Research in AKI 3:30-3:40 AKIN Research Recommendations: A Progress Report Michael Joannidis, MD 3:40-4:00 Clinical Trials in AKI: Design Challenges Ravindra L. Mehta, MBBS, MD, DM, FACP, 4:00-4:20 Cardiology Trials Peter A. McCullough, MD, MPH 4:20-4:40 Sepsis Trials John Louis Vincent, MD PhD 4:40-5:00 Issues in Pediatric AKI Trials Stuart L. Goldstein, MD 5:00-5:20 Regulatory Aspects of Trials in AKI Shen Xiao, MD., Ph.D 5:20-6:00 Interactive Discussion: Endpoints and Outcomes in AKI? What Criteria? John A. Kellum, MD 6:00pm AKI Worskhop Adjourns Wednesday, February 24 Full Day Concurrent Workshops- HW1 8:00-5:15 Co-chair: Jorge Cerda, MD, FACP, FASN Co-chair: Ashita Tolwani, MD 8:00-5:15 HW1 Fundamentals of CRRT This workshop offers an introduction to CRRT techniques and is developed to provide a core set of information on the principles and practice of CRRT. This workshop will cover the components and basic principles of continuous renal replacement therapy. The operating characteristics of CRRT techniques for solute and fluid management, drug management will be discussed along with the potential applications of these techniques. Requirements for developing a successful CRRT program and selecting machines will also be described. 8:00-8:30 Operating Principles of CRRT William R. Clark, MD 8:30-9:00 Access/Membrane and Circuit Miet Schetz, MD, PhD 9:00-9:30 Anticoagulation Ashita Tolwani, MD 9:30-10:00 Solute Control and Dose William R. Clark, MD 10:00-10:15 Discussion 10:15-10:30 Coffee Break 10:30-11:00 Solutions Ashita Tolwani, MD 11:00-11:30 Fluid Management Ravindra L. Mehta, MBBS, MD, DM, FACP, 11:30-12:00 Drug Management Bruce A. Mueller, PharmD, FCCP, FASN 12:00-12:30 Patient Selections and Outcomes Jorge Cerda, MD, FACP, FASN 12:30-12:45 Discussion 12:45-1:30 Lunch Hosted by Conference for Workshop Participants 1:30-2:00 Organizational and Financial Aspects Jorge Cerda, MD, FACP, FASN 2:00-2:30 Pharmacy Support Linda Awdishu, PharmD, MAS 2:30-3:00 Nursing Issues Eileen Lischer, MA, BSN RN 3:00-3:15 Discussion 3:15-3:30 Coffee Break 3:30-4:15 Common 'Myths and Misunderstandings' w/ CRRT Interactive Question and Answer Session (Panel) Linda Awdishu, PharmD, MAS Jorge Cerda, MD, FACP, FASN William R. Clark, MD Eileen Lischer, MA, BSN RN Miet Schetz, MD, PhD 4:15-5:15 CRRT Machine Comparisons Jorge Cerda, MD, FACP, FASN Ashita Tolwani, MD 5:15 Fundamentals Workshop Adjourns Half Day (Morning) Concurrent Workshop-HW2 8:00-12:30 8:00-12:30 HW2 GAMBRO Workshop - NURSES Synopsis: This workshop is designed for nurses who support CCRT therapy and will offer a practical and systematic approach to managing patients on CRRT. The workshop will include patient case studies, order set review, P.A.C.E. methodology and hands on Prismaflex Circuit management. From basics to advanced CRRT circuit management, work with the Gambro Therapy Specialist team to optimize your Prismaflex CRRT Skills! CME Credits Do Not Apply 12:30-1:30 Lunch Hosted by Conference for Workshop Participants Half Day (Afternoon) Concurrent Workshops-HW3 and HW4 1:30-5:15 / 5:30 1:30-5:30 HW3 GAMBRO Workshop - Physicians Synopsis: This workshop will offer CRRT prescribing physicians a consolidated body of evidence for prescribing and delivering CRRT with Gambro's Prismaflex System. The workshop will include lecture, order set review and discussion by CRRT physician prescribers. The session will provide you with the practical knowledge to optimize patient outcomes though enhanced understanding and application of CRRT. CME Credits Do Not Apply Half Day (Afternoon) Concurrent Workshops-HW3 and HW4 1:30-5:15 1:30-5:15 HW4 How to Deliver CRRT to Pediatric Patients, from Neonates to Adolescents Steven R. Alexander, MD Amelia Allsteadt, BSN,RN,CNN Cheryl Baker, BSN, RN Patrick D. Brophy, MD, FAAP, FRCPC Timothy E. Bunchman, MD Helen Currier, BSN, RN, CNN Stuart L. Goldstein, MD This workshop will focus upon the practical aspects of care including clinical program development, discussion of various models of ICU and Nephrology medical nursing care and hands on machine setup and operation. 5:30-8:00pm Conference Registration Open 6:00-7:30pm Reception and Poster Review Thursday Morning, February 25 7:00am-7:30pm Conference Registration Open 8:30am-10:00am STANDARD WORKSHOPS (open to all participants - applicable to physicians, nurses and allied personnel) (Codes: C= Core workshop, I = Intermediate, A = Advanced, N= Nurses, AP = of interest to nurses and allied personnel) Workshops designated by an asterisk (*) will be presented twice in different time slots. Workshops presented in a series are marked with a 1 for a primary workshop discussion in this area and 2 for a more complex or advanced discussion in this area. Please note that the series workshops 1 and 2 can be either taken subsequently (following each other) or they can each be taken independently (e.g. workshop 1 can be taken without taking workshop 2 and vice versa). Workshop Group 1 8:30-10:00 8:30-10:00 A01 CRRT Systems I I. B.Braun Diapact Device demonstrations of features, setup, operation, monitoring and discontinuation CME Credit Does Not Apply 8:30-10:00 A01 II. Gambro's Prismaflex & MARS Device demonstrations of features, setup, operation, monitoring and discontinuation CME Credit Does Not Apply 8:30-10:00 B02 Vascular Access /Membrane and Circuit Nigel Fealy, RN, MN, ACCCN Miet Schetz, MD, PhD Principles of catheter choice, placement, maintenance, recognition and management of complications, selection and use of membranes for different applications, circuit design, setup and monitoring 8:30-10:00 C03 Dialysis Dose Prescription and Delivery William R. Clark, MD Operational characteristics influencing solute removal in CRRT 8:30-10:00 D04 Critical Care Pharamacology: Vasopresors, and Ionotropes Bruce A. Mueller, PharmD, FCCP, FASN Andrew D. Shaw, MD FRCA FCCM John Louis Vincent, MD PhD Pathophysiology of shock and the principles and practical use of vasopressors, ionotropes , vasodilators in critically ill patients. 8:30-10:00 E05 Biomarkers 1: Principles and Applications Kathleen Liu, MD Alan Maisel, MD Patrick T. Murray, MD Principles and classification of biomarkers and their application for diagnosis and management of diseases. Criteria for using biomarkers as surrogate end points. 8:30-10:00 F06 Extracorporeal Techniques for Sepsis 1: Pathophysiology and Targets Patrick M. Honoré, MD Dawei Liu, MD, FCCM William L. Macias, MD, PhD Pathophysiology of sepsis and rationale for use of extracorporeal support in treatment of sepsis. Experimental models for high permeability membranes, HVHF, VHVHF and hybrid therapies 8:30-10:00 G07 Competency Assessment in CRRT Patty Graham, RN, MS, CCRN, CS Eileen Lischer, MA, BSN RN Description on training requirements, core curriculum and skills assessment for CRRT care delivery. 8:30-10:00 H08 Fluids and Solutions in the Critically Ill 1 Noel Gibney, MD Dileep N. Lobo, MD Timothy E. Miller, MB ChB How to select and use colloids, crystalloids and blood products. 8:30-10:00 I09 CRRT Systems II I. Fresenius - CRRT/SLED Systems Device demonstrations of features, setup, operation, monitoring and discontinuation CME Credit Does Not Apply 10:00-10:15 Coffee Break Workshop Group 2 10:15-11:45 10:15-11:45 A09 CRRT Systems III I. NxStage Therapy System Device demonstrations of features, setup, operation, monitoring and discontinuation CME Credit Does Not Apply 10:15-11:45 A09 II. Baxter Healthcare - Aquarius System Device demonstrations of features, setup, operation, monitoring and discontinuation CME Credit Does Not Apply 10:15-11:45 B10 Anticoagulation: Mechanisms and Techniques Michael Joannidis, MD Ashita Tolwani, MD Anticoagulation regimens: Mechanisms, selection, prescription, monitoring and implementation 10:15-11:45 C11 Fluid Management Ravindra L. Mehta, MBBS, MD, DM, FACP, Timothy E. Miller, MB ChB Principles of volume assessment, fluid removal and fluid regulation with different CRRT equipment 10:15-11:45 D12 Critical Care Management: Nutrition Assessment and Delivery Oliver Joannes-Boyau, MD Dileep N. Lobo, MD John Louis Vincent, MD PhD Pathophysiology of malnutrition in critically ill patients. Principles of nutritional assessment and support and adjustments for RRT. 10:15-11:45 E13 Biomarkers 2: Application in AKI Josée Bouchard, MD Prasad Devarajan, MD Patrick T. Murray, MD Development and qualification of structural and functional biomarkers for AKI. Current performance characteristics and application for diagnosis, management and prognostication in AKI. 10:15-11:45 F14 Liver and the Kidney 1: Principles of Hepatic Dysfunction Andrew Davenport, MD, FRCP Rajiv Jalan, MD, PhD Pathophysiology of hepatic failure and rationale for use of different techniques for extracorporeal support techniques (Cell based systems, MARS, CRRT) for hepatic support 10:15-11:45 G15 Therapy Comparisons : SLED vs. CRRT vs. PD Rajasekara Chakravarthi, MD, DNB (Nephrology) Mark R. Marshall, MBChB, FRACP, MPH Comparisons of operational characteristics including anticoagulation, membranes, solutions and flows and approaches for ongoing and future research 10:15-11:45 H16 Pediatric CRRT: The Basics Steven R. Alexander, MD David Askenazi, MD Geoffrey Fleming, MD Jordan M. Symons, MD Michael Zappitelli, MD, MSc Technique requirement and application for use in children excluding neonates. Topics covered will include the epidemiology of pediatric acute kidney injury, and a focus on the pediatric CRRT prescription (anticoagulation, fluid composition, modality, and nutrition provision), as well as outcome in pediatric CRRT. 11:45-1:15 Lunch Hosted by Conference 11:45-1:15 SPECIAL LUNCH FORUM Multigenerational Differences in the Workplace Michele L. Deck The rapidly changing healthcare environment poses challenges in recruiting, nurturing and retaining care providers. This session will focus on the evolving changes in the generational gap and its effects on the workplace. Topics will include a discussion of factors that are crucial in motivating people in different generations and how these can be utilized effectively to implement change and improve patient care. 11:45-1:15 AngioDynamics Focus Group Luncheon Targeted Renal Therapy for the Prevention and Treatment of Acute Kidney Disease This focus group is targeted at nephrologists who often care for patients with acute kidney injury and can engage in a discussion about treatment options, what works, what is needed, and what protocols should be put in place at institutions to address these issues. Participants will also be asked to evaluate Targeted Renal Therapy and the suspected benefits, issues, and barriers to adoption. Limited space - please contact: VBerwaldt@AngioDynamics.com 11:45-1:15 Inverness Medical Innovations Focus Group Luncheon The Emerging Utility of NGAL in the Intensive Care Unit This focus group is targeted at clinical specialists who would like to learn more about the novel role of Neutrophil Gelatinase-Associated Lipocalin (NGAL) as an aid to the early diagnosis and prognosis of renal injury (AKI) in the ICU. Several speakers will present key data and opinions highlighting the diagnostic and prognostic utility of NGAL and its evolving role in therapeutic interventions that could prevent the progression of AKI in patients in the ICU. Please join us as our distinguish program chair Claudio Ronco, MD, St. Bortolo Hospital Vicenza, Italy, hosts the following guest speakers: NGAL is an Early Biomarker for AKI in an Adult ICU Population Dinna Cruz, MD, MPH St. Bortolo Hospital Vicenza, Italy NGAL At ICU Admission Predict for Severe AKI in Adult Critically Ill Patients Hilde De Geus, MD, Erasmus University Medical Center NGAL for Recovery from Sepsis-Induced AKI John Kellum, MD, FACP, FCCM Limited space - please contact: rfenimore@biosite.com Thursday Afternoon, February 25 SESSION I: PATIENT CHARACTERISTICS Plenary 1 MINI-SYMPOSIA Organ Dysfunction in the Critically Ill Patient: Emerging Concepts 1:15-3:45 Co-chair: Lakhmir S. Chawla, MD Co-chair: William L. Macias, MD, PhD 1:15-1:20 Opening Remarks Ravindra L. Mehta, MBBS, MD, DM, FACP, 1:20-1:40 Sepsis and the Kidney Martin Matejovic, MD 1:40-2:00 Increased Intra-abdominal Pressure: Does it Contribute to Multiorgan Failure? Dileep N. Lobo, MD 2:00-2:20 Hepatic Dysfunction and the Kidney in Critical Illness Rajiv Jalan, MD, PhD 2:20-2:40 Mechanisms Underlying Distant Organ Dysfunction and High Mortality from AKI Hamid Rabb, MD 2:40-3:00 Near Infrared Spectroscopy for Non-invasive Monitoring of Regional Blood Flow Dean B. Andropoulos, MD 3:00-3:30 SPECIAL LECTURE Current Management of Severe Sepsis and Septic Shock John Louis Vincent, MD PhD 3:30-3:45 Panel Discussion 3:45-4:15 Coffee Break Plenary 2 MINI-SYMPOSIA Acute Kidney Injury (AKI): Pathophysiology 4:00-6:00 Co-chair: Mark D. Okusa, MD Co-chair: John Louis Vincent, MD PhD 4:15-4:35 Central Role of Activated Leukocytes in Acute Kidney Injury H. David Humes, MD 4:35-4:55 Mechanisms of Repair from AKI: Leukocytes, Stem Cells, Growth Factors Hamid Rabb, MD 4:55-5:15 Early Events in Clinical AKI: Does Endothelial Dysfunction Occur? Josée Bouchard, MD 5:15-5:35 Post Cardiac Surgery AKI: Have We Made Progress? Andrew D. Shaw, MD FRCA FCCM 5:35-6:00 SPECIAL LECTURE Biomarkers in AKI: New Insights into Pathophysiology? Patrick T. Murray, MD 6:00-6:15 Panel Discussion 6:15 Adjourn 6:15-7:30 Exhibit Reception and Poster Session Friday Morning, February 26 7:00am-4:00pm Registration SESSION 2: EMERGING CONCEPTS IN AKI AND CRITICAL CARE Plenary 3 MINI-SYMPOSIA Controversies in Management of the Critically Ill Patient: Fluid Management 7:30-9:45 Co-chair: Noel Gibney, MD Co-chair: Peter A. McCullough, MD, MPH 7:25-7:30 Announcements 7:30-7:50 Fluid Overload: Cause or Consequence of Critical Illness? Dileep N. Lobo, MD 7:50-8:10 Assessing Volume Status: What Measures Dawei Liu, MD, FCCM 8:10-8:30 Perioperative Fluid Optimization Timothy E. Miller, MB ChB 8:30-8:50 Optimizing Lung Function: Fluid Management in Respiratory Failure Kathleen Liu, MD 8:50-9:10 Nursing Issues in Fluid Optimization Nigel Fealy, RN, MN, ACCCN 9:10-9:30 DEBATE Fluid Management in AKI: 'Fill and Spill' or 'Squeeze and Diurese?' John Louis Vincent, MD PhD 9:30-9:45 Panel Discussion 9:45-10:15 Coffee Break Plenary 4 MINI-SYMPOSIA Challenges and Controversies in Renal Support and CRRT 10:15-1:00 Co-chair: Michael Joannidis, MD Co-chair: Paul Palevsky, MD 10:15-10:30 Drug Dosing in RRT: Do We Under Deliver? Linda Awdishu, PharmD, MAS 10:30-10:45 Measuring Dialysis Dose in CRRT: A Comparison of Techniques Rolando Claure, MD 10:45-11:00 Dialytrauma: Concept and Options to Avoid It Javier Maynar, MD 11:00-11:40 RRT in the ICU Across the World India, China, Latin America, Japan Emmanuel Burdmann, MD, PhD Rajasekara Chakravarthi, MD, DNB (Nephrology) Kazo Kaizu, MD Dawei Liu, MD, FCCM 11:40-11:55 Blood Purification in Sepsis: Do We Have it All Wrong? John A. Kellum, MD 11:55-12:10 Decap: The Missing Piece of MOST 12:10-12:25 Timing of Dialysis: Time for a Personalized Approach? Ravindra L. Mehta, MBBS, MD, DM, FACP, 12:25-12:45 The KDIGO Guidelines for AKI John A. Kellum, MD 12:45-1:00 Panel Discussion 1:00-2:30 Lunch Hosted by Conference 1:00-2:30 Special Panel Discussion Fluid Management & Renal Support: Challenges and Opportunities Friday Afternoon, February 26 2:30-6:00 STANDARD WORKSHOPS Workshop Group 3 2:30-4:00 2:30-4:00 A17 CRRT Systems I I. B. Braun Diapact Device demonstrations of features, setup, operation, monitoring and discontinuation CME Credit Does Not Apply 2:30-4:00 A17 II. Gambro's Prismaflex & MARS Device demonstrations of features, setup, operation, monitoring and discontinuation CME Credit Does Not Apply 2:30-4:00 B18 Drug Management in CRRT Javier Maynar, MD Bruce A. Mueller, PharmD, FCCP, FASN Miet Schetz, MD, PhD Drug Dosing principles for critically ill patients and adjustments in extracorporeal support techniques. 2:30-4:00 C19 Starting and Stopping RRT for AKI: Principles and Practice Emmanuel Burdmann, MD, PhD Ravindra L. Mehta, MBBS, MD, DM, FACP, Principles of determining when to start and stop RRT. Case based dsicussion of various approaches. 2:30-4:00 D20 KDIGO Guidelines for AKI 1: Definition and Prevention Michael Joannidis, MD John A. Kellum, MD Patrick T. Murray, MD These two workshops (with D28) will describe the KDIGO evidence based guidelines for management of Acute Kidney Injury due to be released in 2010. Session 1 covers Diagnosis and Prevention and session 2 Non-dialytic and Dialytic Management of AKI. These interactive sessions will discuss the basis of the recommendations and provide an opportunity for feedback to the members of the KDIGO team. 2:30-4:00 E21 Ensuring Patient Safety and Quality Measures for RRT in AKI 1: Water Standards, Infection Control Nigel Fealy, RN, MN, ACCCN Eileen Lischer, MA, BSN RN Mark R. Marshall, MBChB, FRACP, MPH This group of workshops discusses the recent developments in ensuring quality and patient safety for acute dialysis delivery. Session 1 (E21) covers the new quality standards for water treatment, infection control and dialysis dose delivery. Session 2 (E29) Discusses the principles of a systems based approach to implementing and monitoring quality to reduce errors in therapy prescription and delivery. 2:30-4:00 F22 Heart Failure and Cardio-renal Syndrome 1: Pathophysiology Alan Maisel, MD Pathophysiology, recognition and management strategies for cardiac and renal failure in the critically ill patient. 2:30-4:00 G23 Extracorporeal Techniques for Sepsis 2 Patrick M. Honoré, MD H. David Humes, MD Martin Matejovic, MD Technical considerations and practical application of extracorporeal support techniques for sepsis. Results of human studies for use of high permeability membranes, HVHF, VHVHF and hybrid techniques for sepsis 2:30-4:00 H24 Fluids and Solutions in the Critically Ill 2 Andrew Davenport, MD, FRCP Ashita Tolwani, MD Currently available solutions for CRRT and dialysis. Practical approaches for achieving metabolic, acid-base, electrolyte and divalent ion control with RRT techniques. 2:30-4:00 I25 CRRT Systems II I. Fresenius - CRRT/SLED Systems Device demonstrations of features, setup, operation, monitoring and discontinuation CME Credit Does Not Apply 4:00-4:30 Coffee Break Workshop Group 4 4:30-6:00 4:30-6:00 A25 CRRT Systems III I. NxStage Therapy System Device demonstrations of features, setup, operation, monitoring and discontinuation. CME Credit Does Not Apply 4:30-6:00 A25 II. Baxter Healthcare - Aquarius System Device demonstrations of features, setup, operation, monitoring and discontinuation. CME Credit Does Not Apply 4:30-6:00 B26 Building Bridges Leading the Generations Michele L. Deck Determinants of change in the work environment. Tools and strategies for dealing with the generational gap, conflict resolution and implementing effective change. 4:30-6:00 C27 Plasma Exchange Therapy and Hybrid Techniques Oliver Joannes-Boyau, MD Javier Maynar, MD David M. Ward, MD, FRCP Principles of plasma exchange, sorbent based and hybrid therapies for extracorporeal support. Case based discussion of practical application of plasma exchange, sorbent based and hybrid therapies for extracorporeal support. 4:30-6:00 D28 KDIGO Guidelines for AKI 2: Non-dialytic and Dialytic Management John A. Kellum, MD Miet Schetz, MD, PhD These two workshops (with D20) will describe the KDIGO evidence based guidelines for management of Acute Kidney Injury due to be released in 2010. Session 1 covers Diagnosis and Prevention and session 2 Non-dialytic and Dialytic Management of AKI. These interactive sessions will discuss the basis of the recommendations and provide an opportunity for feedback to the members of the KDIGO team. 4:30-6:00 E29 Ensuring Patient Safety and Quality Measures for RRT in AKI 2: Dialysis Adequacy, Monitoring, Nursing Issues Linda Awdishu, PharmD, MAS Eileen Lischer, MA, BSN RN Ravindra L. Mehta, MBBS, MD, DM, FACP, This group of workshops discusses the recent developments in ensuring quality and patient safety for acute dialysis delivery. Session 1 (E21) covers the new quality standards for water treatment, infection control and dialysis dose delivery. Session 2 (E29) Discusses the principles of a systems based approach to implementing and monitoring quality to reduce errors in therapy prescription and delivery. 4:30-6:00 F30 Heart Failure and Cardio-Renal Syndrome 2: Management Strategies and Case Studies Alan Maisel, MD Emil P. Paganini, MD, FACP, FRCP Technical considerations, practical application and results of different methods to treat heart failure and cardio-renal syndrome 4:30-6:00 G31 Liver and Kidney 2: Hepatic Support Andrew Davenport, MD, FRCP Rajiv Jalan, MD, PhD Technical considerations, practical application and results of different methods of hepatic support for patients with hepatic failure and hepatorenal syndrome 4:30-6:00 H32 CRRT in the New Born: Principles and Application Nursing Issues in Neonatal CRRT David Askenazi, MD Timothy E. Bunchman, MD Pathophysiology and management of metabolic disorders, neonatal AKI and intoxications with CRRT. 6:00 Adjourn Saturday Morning, February 27 7:00-5:00 Registration SESSION III: TECHNIQUE CHARACTERISTICS 7:25-7:30 Announcements Plenary 5 MINI SYMPOSIA Emerging Concepts in AKI 7:30-10:05 Co-chair: Stuart L. Goldstein, MD Co-chair: Bruce A. Molitoris, MD 7:30-7:50 Do Episodes of Oliguria Reflect Acute Kidney Injury in Critically Ill Patients? Etienne Macedo, MD 7:50-8:10 AKI in Disasters: Lessons from Haiti Emmanuel Burdmann, MD, PhD Noel Gibney, MD 8:10-8:30 Acute Kidney Injury and Chronic Kidney Disease Lakhmir S. Chawla, MD 8:30-8:50 'Adding Insult to Injury': The NCEPOD Findings and Recommendations Andrew Lewington, MD 8:50-9:10 Variations in Care for AKI: The USRDS experience Paul Eggers, PhD 9:10-9:30 Risk Assessment for AKI: Development of a Scoring System Ravindra L. Mehta, MBBS, MD, DM, FACP, 9:30-9:50 Contrast Nephropathy: Prevention and Management Peter A. McCullough, MD, MPH 9:50-10:05 Panel Discussion 10:05-10:30 Coffee Break SESSION IV: FUTURE TRENDS IN CRRT AND CRITICAL CARE Plenary 6 MINI SYMPOSIA Emerging Strategies in AKI and Extracorporeal Support 10:30-1:00 Co-chair: Bruce A. Mueller, PharmD, FCCP, FASN Co-chair: Miet Schetz, MD, PhD 10:30-10:50 Early Clinical Evaluation of a Novel Cytopheretic Membrane Device (SCD) in Patients with Acute Kidney Injury H. David Humes, MD 10:50-11:05 H1N1 and the Kidney Noel Gibney, MD 11:05-11:20 CRRT for Non-AKI Indications in Peds Stem Cell/Cancer Patients Joseph V. DiCarlo, MD 11:20-11:35 Uric Acid Oxidase for Treatment of AKI: A New Pharmacologic Option? Timothy E. Bunchman, MD 11:35-11:55 Biological Extracorporeal Liver Support Rajiv Jalan, MD, PhD 11:55-12:15 Regulatory Requirements for RRT Devices and Solutions Kevin McBryde, MD 12:15-12:35 Critical Care Nephrology: Literature Review Noel Gibney, MD 12:35-12:55 Discussion 12:55-1:00 Closing Remarks Ravindra L. Mehta, MBBS, MD, DM, FACP, 1:00 Conference Adjourns Saturday Afternoon, February 27 2:00-5:30 CONCURRENT ELECTIVE HANDS-ON WORKSHOPS 1:00-2:00 Lunch Hosted by Conference for Workshop Participants Concurrent Elective Hands-On Workshops 2:00-5:30 2:00-5:30 HW5 Fresenius Workshop SLED, CRRT and IHD with the 2008K2 Learn how to us the Fresenius system for SLED, CRRT and IHD for acute renal failure. CME Credits Do Not Apply 2:00-5:30 HW6 Hemodynamic Monitoring and Use of Drugs Lakhmir S. Chawla, MD Timothy E. Miller, MB ChB Bruce A. Mueller, PharmD, FCCP, FASN Critically ill Patients require frequent assessments and monitoring of hemodynamic and respiratory parameters to optimize stability and guide ventilator support. Several techniques are now available and utilized to manage patients including devices to assess the microcirculation, volume responsiveness and cardiac performance. This workshop will cover the principles and strategies for hemodynamic and microcirculatory monitoring and ventilator management in critically ill patients. 2:00-5:30 HW7 Essentials for Developing, Nurturing and Growing a CRRT Program Linda Awdishu, PharmD, MAS Jorge Cerda, MD, FACP, FASN Nigel Fealy, RN, MN, ACCCN Eileen Lischer, MA, BSN RN Successful CRRT programs require careful planning, nurturing and ongoing monitoring for growth and effectiveness.. This workshop will cover the key elements for building and enhancing a program. Topics to be covered include developing a multidisciplinary team, creating tool kits for training, assessments and monitoring effectiveness of the program, dealing with administration, financial considerations and strategies for program growth. 2:00-3:15 Session 1 3:15-3:30 Coffee Break 3:30-5:30 Session 2 5:30 Workshops Adjourn