Invited lectures, workshops, dedicated sessions for nursing, poster sessions and panel discussions are being planned to continue the tradition of multidisciplinary interactions. This year’s program again promises to provide the right environment to foster learning and mutually beneficial interactions and collaborations.

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AKI & CRRT 2019 – February 26 – March 1, 2019

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Monday, February 25

1:00-7:00pm
Conference and Workshop Registration Open

Practice Based Learning in CRRT: The Science and the Art

This workshop is designed to provide participants with the knowledge and understanding for the effective utilization of CRRT to manage critically ill patients. Session 1 on Monday focuses on the fundamentals of CRRT including the components, operational characteristics and characteristics, solute and fluid management and monitoring. Session 2 on Tuesday will utilize case based discussions and interactive sessions to illustrate the underlying concepts for application of CRRT in different situations. Delegates will participate in group exercises to apply their learning for the management of complex cases. At the end of this workshop participants will have an improved understanding of how to utilize CRRT for optimizing renal support. A quiz will be administered pre-and post- course for assessment.
CRRT Workshop - Day 1
1:45-6:00

Jorge Cerda, MD, MS, FACP, FASN

Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY Clinical Associate Professor of Medicine, Albany Medical College, Albany NY Fulbright Scholar, 1980 Fellow, American College of Physicians Fellow, American Society of Nephrology Organizing Committee, International Conference AKI & CRRT AKI Advisory Group, American Society of Nephrology AKI Committee, and "0by25" Initiative, International Society of Nephrology Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease Associate Editor, Blood Purification and Kidney International Reports Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world

Ashita Tolwani, MD

Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
1:45-2:00
Opening Remarks

Jorge Cerda, MD, MS, FACP, FASN

Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY Clinical Associate Professor of Medicine, Albany Medical College, Albany NY Fulbright Scholar, 1980 Fellow, American College of Physicians Fellow, American Society of Nephrology Organizing Committee, International Conference AKI & CRRT AKI Advisory Group, American Society of Nephrology AKI Committee, and "0by25" Initiative, International Society of Nephrology Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease Associate Editor, Blood Purification and Kidney International Reports Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world

Ashita Tolwani, MD

Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
2:00-2:30
Pre-Test

Jorge Cerda, MD, MS, FACP, FASN

Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY Clinical Associate Professor of Medicine, Albany Medical College, Albany NY Fulbright Scholar, 1980 Fellow, American College of Physicians Fellow, American Society of Nephrology Organizing Committee, International Conference AKI & CRRT AKI Advisory Group, American Society of Nephrology AKI Committee, and "0by25" Initiative, International Society of Nephrology Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease Associate Editor, Blood Purification and Kidney International Reports Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world

Ashita Tolwani, MD

Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
2:30-3:00
Access, Membrane, Circuit

Michael Connor, MD

Dr. Connor is dual trained in nephrology & critical care medicine sharing his clinical duties between critical care medicine & inpatient consultative nephrology. Dr. Connor’s clinical and academic interests are focused heavily on critical care medicine and especially acute nephrology issues in the critically ill. Dr. Connor is an internationally recognized expert on acute renal replacement therapies, acute kidney injury (AKI), antimicrobial dosing in AKI, volume management and hemodynamic support of the critically ill, intra-abdominal hypertension & abdominal compartment syndrome, acute acid/base derangements, and extracorporeal blood purification techniques including extra-corporeal membrane oxygenation. In September 2014, Dr. Connor spearheaded the first-ever application of advanced critical care support to a patient with Ebola virus disease (EVD) which included the first known successful application of acute continuous hemodialysis and mechanical ventilatory support in EVD.
3:00-3:30
Modality & Dose

Jorge Cerda, MD, MS, FACP, FASN

Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY Clinical Associate Professor of Medicine, Albany Medical College, Albany NY Fulbright Scholar, 1980 Fellow, American College of Physicians Fellow, American Society of Nephrology Organizing Committee, International Conference AKI & CRRT AKI Advisory Group, American Society of Nephrology AKI Committee, and "0by25" Initiative, International Society of Nephrology Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease Associate Editor, Blood Purification and Kidney International Reports Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world
3:30-4:00
Anticoagulation

Ashita Tolwani, MD

Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
4:00-4:15
Coffee Break
4:15-4:45
Solutions and Fluid Balance

David Selewski, MD

I am an Assistant Professor in the Department of Pediatrics within the Division of Nephrology at the University of Michigan. I received my training in pediatrics and pediatric nephrology at the University of Michigan. My clinical and research interests include pediatric critical care nephrology including pediatric & neonatal acute kidney injury, fluid overload, and continuous renal replacement therapy.
4:45-5:15
Monitoring

Eileen Lischer, MA, BSN, RN, CNN

Eileen Lischer RN BSN MA has over 37 years of Nephrology nursing experience. She has worked as an educator and a nurse manager. Currently she is the Acute Dialysis Administrative Nurse for all four programs at the University of California Medical Center, San Diego. Her expertise includes adult and pediatric hemodialysis, CRRT, intra operative CRRT, peritoneal dialysis and apheresis. Eileen works collaboratively with the Critical Care Units to educate the primary care nurses in CRRT concepts and system applications. She coordinates a Diabetic Initiative focused on improving patient outcomes through nurse education. Eileen is actively involved in both kidney and liver research projects. She is a lecturer at the UCSD Extension program.
5:15-6:00
Interactive Case Discussion

Ashita Tolwani, MD

Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
6:00pm
Adjourn

Tuesday, February 26

7:00am
Conference and Workshop Registration Open

Practice Based Learning in CRRT: The Science and the Art

8:00-5:30
PW2 Practice Based Learning in CRRT: The Science and the Art
This workshop is designed to provide participants with the knowledge and understanding for the effective utilization of CRRT to manage critically ill patients. Session 1 on Monday focuses on the fundamentals of CRRT including the components, operational characteristics and characteristics, solute and fluid management and monitoring. Session 2 on Tuesday will utilize case based discussions and interactive sessions to illustrate the underlying concepts for application of CRRT in different situations. Delegates will participate in group exercises to apply their learning for the management of complex cases. At the end of this workshop participants will have an improved understanding of how to utilize CRRT for optimizing renal support. A quiz will be administered pre-and post- course for assessment.
Room: Coronado Ballroom
CRRT Workshop - Day 2
8:00-5:30
8:00-12:00
Concurrent Physician and Nurse Tracks
Room: Coronado Ballroom
8:00-8:40
PHYSICIAN - Patient Selection

Jorge Cerda, MD, MS, FACP, FASN

Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY Clinical Associate Professor of Medicine, Albany Medical College, Albany NY Fulbright Scholar, 1980 Fellow, American College of Physicians Fellow, American Society of Nephrology Organizing Committee, International Conference AKI & CRRT AKI Advisory Group, American Society of Nephrology AKI Committee, and "0by25" Initiative, International Society of Nephrology Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease Associate Editor, Blood Purification and Kidney International Reports Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world
8:40-9:00
PHYSICIAN - Drug Dosing and Adjustments

Linda Awdishu, PharmD, MAS

Linda Awdishu earned her Bachelors of Science in Pharmacy from the University of Toronto in 1999, Doctor of Pharmacy from the University of Colorado in 2008 and Masters of Clinical Research from the University of California in 2007. She is an Associate Clinical Professor of Pharmacy and Medicine at UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences. She maintains a clinical practice in the chronic kidney disease program. Her research program is focused on drug induced kidney injury.
9:00-10:00
PHYSICIAN - Correcting Acid Base Abnormalities

David Selewski, MD

I am an Assistant Professor in the Department of Pediatrics within the Division of Nephrology at the University of Michigan. I received my training in pediatrics and pediatric nephrology at the University of Michigan. My clinical and research interests include pediatric critical care nephrology including pediatric & neonatal acute kidney injury, fluid overload, and continuous renal replacement therapy.
10:00-10:20
Coffee Break
10:20-11:00
PHYSICIAN - Managing Hypo and Hypernatremia

Ashita Tolwani, MD

Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
11:00-11:40
PHYSICIAN - Adjusting Nutrition

Michael Connor, MD

Dr. Connor is dual trained in nephrology & critical care medicine sharing his clinical duties between critical care medicine & inpatient consultative nephrology. Dr. Connor’s clinical and academic interests are focused heavily on critical care medicine and especially acute nephrology issues in the critically ill. Dr. Connor is an internationally recognized expert on acute renal replacement therapies, acute kidney injury (AKI), antimicrobial dosing in AKI, volume management and hemodynamic support of the critically ill, intra-abdominal hypertension & abdominal compartment syndrome, acute acid/base derangements, and extracorporeal blood purification techniques including extra-corporeal membrane oxygenation. In September 2014, Dr. Connor spearheaded the first-ever application of advanced critical care support to a patient with Ebola virus disease (EVD) which included the first known successful application of acute continuous hemodialysis and mechanical ventilatory support in EVD.
11:40-12:00
PHYSICIAN - Achieving Survival and Recovery

Stuart Goldstein, MD

Dr. Goldstein serves as Director for the Center for Acute Care Nephrology (CACN) at Cincinnati Children's Hospital Medical Center. The CACN's mission is to coordinate all AKI related clinical, research and outcomes efforts at CCHMC and to function as a nexus for coordinating multi-center pediatric AKI research. Dr. Goldstein is the Founder and Principal Investigator of the Prospective Pediatric AKI Research Group (www.ppaki.org), a 50 center international pediatric acute care nephrology research consortium that will focuses on pediatric AKI epidemiology, interventional trials, device evaluation and genetic studies. Dr. Goldstein is also the program director for the only Pediatric Acute Care Nephrology fellowship in the United States.
8:00-8:40
NURSE - Orders, Charting and Monitoring
8:40-9:00
NURSE - CRRT in the Operating Room

Noel Oabel, BSN, RN, CNN

I have over 23 years of nursing experience with the last 13 years specializing in chronic and acute dialysis setting. I work as assistant nurse manager at University of California San Diego Medical Center Acute Dialysis Unit with expertise in Continuous Renal Replacement Therapy, Peritoneal Dialysis, Intermittent Hemodialysis, Intraoperative SLED and Therapeutic Plasma Exchange.
9:00-10:00
NURSE - CRRT for Pediatric Applications

Theresa Mottes, MSN, RN,CPNP-AC,CDN

Theresa Mottes has over 20 years of pediatric renal replacement therapy experience is both the critical care setting and the outpatient dialysis setting. She has been involved in research with acute kidney injury, continuous renal replacement therapies and simulation based education for CRRT training. Theresa currently is a nurse practitioner for critical care nephrology. Theresa is very active with ANNA, as the current Pediatric Specialty Practice Network facilitator. She has presented at both national and international conferences.
10:00-10:20
Coffee Break
10:20-11:00
NURSE - Patient Mobilization and Rehabilitation

Eileen Lischer, MA, BSN, RN, CNN

Eileen Lischer RN BSN MA has over 37 years of Nephrology nursing experience. She has worked as an educator and a nurse manager. Currently she is the Acute Dialysis Administrative Nurse for all four programs at the University of California Medical Center, San Diego. Her expertise includes adult and pediatric hemodialysis, CRRT, intra operative CRRT, peritoneal dialysis and apheresis. Eileen works collaboratively with the Critical Care Units to educate the primary care nurses in CRRT concepts and system applications. She coordinates a Diabetic Initiative focused on improving patient outcomes through nurse education. Eileen is actively involved in both kidney and liver research projects. She is a lecturer at the UCSD Extension program.
11:00-11:40
NURSE - Integrating Multidisciplinary Support Team for CRRT Delivery

Linda Awdishu, PharmD, MAS

Linda Awdishu earned her Bachelors of Science in Pharmacy from the University of Toronto in 1999, Doctor of Pharmacy from the University of Colorado in 2008 and Masters of Clinical Research from the University of California in 2007. She is an Associate Clinical Professor of Pharmacy and Medicine at UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences. She maintains a clinical practice in the chronic kidney disease program. Her research program is focused on drug induced kidney injury.
11:40-12:00
NURSE - Developing Quality Measures for CRRT Delivery

Eileen Lischer, MA, BSN, RN, CNN

Eileen Lischer RN BSN MA has over 37 years of Nephrology nursing experience. She has worked as an educator and a nurse manager. Currently she is the Acute Dialysis Administrative Nurse for all four programs at the University of California Medical Center, San Diego. Her expertise includes adult and pediatric hemodialysis, CRRT, intra operative CRRT, peritoneal dialysis and apheresis. Eileen works collaboratively with the Critical Care Units to educate the primary care nurses in CRRT concepts and system applications. She coordinates a Diabetic Initiative focused on improving patient outcomes through nurse education. Eileen is actively involved in both kidney and liver research projects. She is a lecturer at the UCSD Extension program.
12:00-1:00
Lunch Hosted by Conference for Workshop Participants
1:10-4:00
Interactive Physician and Nurse Tracks
These sessions will have nurses, physicians and pediatric tracks. Physicians will be guided on user interfaces and the strategies for prescribing dose for solute and fluid management, adjustments in therapy parameters, recognition and management of complications. Nurses will learn how to set up for different modalities and adjust and monitor for therapy delivery based on the prescription.
Room: Coronado Ballroom
1:10-4:00
PHYSICIAN - Circuit, Anticoagulation and Monitoring

Noel Oabel, BSN, RN, CNN

I have over 23 years of nursing experience with the last 13 years specializing in chronic and acute dialysis setting. I work as assistant nurse manager at University of California San Diego Medical Center Acute Dialysis Unit with expertise in Continuous Renal Replacement Therapy, Peritoneal Dialysis, Intermittent Hemodialysis, Intraoperative SLED and Therapeutic Plasma Exchange.

Ashita Tolwani, MD

Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
1:10-4:00
PHYSICIAN - Dose / Fluid / Documentation / Recognizing and Managing Complications

Michael Connor, MD

Dr. Connor is dual trained in nephrology & critical care medicine sharing his clinical duties between critical care medicine & inpatient consultative nephrology. Dr. Connor’s clinical and academic interests are focused heavily on critical care medicine and especially acute nephrology issues in the critically ill. Dr. Connor is an internationally recognized expert on acute renal replacement therapies, acute kidney injury (AKI), antimicrobial dosing in AKI, volume management and hemodynamic support of the critically ill, intra-abdominal hypertension & abdominal compartment syndrome, acute acid/base derangements, and extracorporeal blood purification techniques including extra-corporeal membrane oxygenation. In September 2014, Dr. Connor spearheaded the first-ever application of advanced critical care support to a patient with Ebola virus disease (EVD) which included the first known successful application of acute continuous hemodialysis and mechanical ventilatory support in EVD.
1:10-4:00
PHYSICIAN - Prescription / Order Sets / Decision Making / Coordination of Care

Linda Awdishu, PharmD, MAS

Linda Awdishu earned her Bachelors of Science in Pharmacy from the University of Toronto in 1999, Doctor of Pharmacy from the University of Colorado in 2008 and Masters of Clinical Research from the University of California in 2007. She is an Associate Clinical Professor of Pharmacy and Medicine at UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences. She maintains a clinical practice in the chronic kidney disease program. Her research program is focused on drug induced kidney injury.

Jorge Cerda, MD, MS, FACP, FASN

Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY Clinical Associate Professor of Medicine, Albany Medical College, Albany NY Fulbright Scholar, 1980 Fellow, American College of Physicians Fellow, American Society of Nephrology Organizing Committee, International Conference AKI & CRRT AKI Advisory Group, American Society of Nephrology AKI Committee, and "0by25" Initiative, International Society of Nephrology Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease Associate Editor, Blood Purification and Kidney International Reports Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world
1:10-4:00
PHYSICIAN - Monitoring, Alarms and Connections with Other Therapies

Katrina Eggleston, MSN, RN

Katrina has been working in acute dialysis for over 14 years as a preceptor and charge nurse. She now holds the position of Manager of CRRT, traveling to acute facilities training their staff on CRRT.

Keith Wille, MD

Keith Wille, MD, MSPH is currently a Professor of Medicine at the University of Alabama at Birmingham (UAB). Dr. Wille completed fellowship training in Pulmonary and Critical Care Medicine at UAB and joined the faculty in 2000. His clinical interests are in critical care medicine, extracorporeal support technologies, and cardiothoracic transplantation. He received an MSPH degree in clinical epidemiology from the UAB School of Public Health in 2013. He is Medical Director of the UAB Adult ECMO and Advanced Lung Diseases Programs and organized the first annual UAB Extracorporeal Life Support Symposium, recently held in February.
1:10-4:00
NURSE - Machine Priming, Circuit Set Up, Programing to Match Orders

Katrina Eggleston, MSN, RN

Katrina has been working in acute dialysis for over 14 years as a preceptor and charge nurse. She now holds the position of Manager of CRRT, traveling to acute facilities training their staff on CRRT.
1:10-4:00
NURSE - Implementing Therapy Delivery Dose Adjustments, Fluid Balance

Eileen Lischer, MA, BSN, RN, CNN

Eileen Lischer RN BSN MA has over 37 years of Nephrology nursing experience. She has worked as an educator and a nurse manager. Currently she is the Acute Dialysis Administrative Nurse for all four programs at the University of California Medical Center, San Diego. Her expertise includes adult and pediatric hemodialysis, CRRT, intra operative CRRT, peritoneal dialysis and apheresis. Eileen works collaboratively with the Critical Care Units to educate the primary care nurses in CRRT concepts and system applications. She coordinates a Diabetic Initiative focused on improving patient outcomes through nurse education. Eileen is actively involved in both kidney and liver research projects. She is a lecturer at the UCSD Extension program.
1:10-4:00
NURSE - Therapy Monitoring and Troubleshooting Alarms, Therapy Discontinuation

Noel Oabel, BSN, RN, CNN

I have over 23 years of nursing experience with the last 13 years specializing in chronic and acute dialysis setting. I work as assistant nurse manager at University of California San Diego Medical Center Acute Dialysis Unit with expertise in Continuous Renal Replacement Therapy, Peritoneal Dialysis, Intermittent Hemodialysis, Intraoperative SLED and Therapeutic Plasma Exchange.
1:10-4:00
NURSE - Connectology with Hybrid Systems ECMO, ECCOR, Apheresis

Isagani Marquez, MSN, RN, QIA

1:10-4:00
PEDIACTRIC SESSION
Modality Selection, Circuit Modifications, Therapy Dosing, Monitoring, Adjustments for Targeted Interventions

David Askenazi, MD, MSPH

Dr. Askenazi is the Medical Director of the Pediatric and Infant Center for Acute Nephrology (PICAN), whose mission is to impove the outcomes of infants and children at risk for acute kidney disease by performing excellent comprehensive multi-disciplinary care, research and education. Dr. Askenazi's research interest include: a) the role that acute kidney injury (AKI) has on short and long-term outcomes in neonates and pediatric patients, b) testing therapies to improve the short and long-term outcomes of neonates and pediatric patients with AKI, and c) improving the definition of neonatal AKI using urinary and serum biomarkers of AKI.

Stuart Goldstein, MD

Dr. Goldstein serves as Director for the Center for Acute Care Nephrology (CACN) at Cincinnati Children's Hospital Medical Center. The CACN's mission is to coordinate all AKI related clinical, research and outcomes efforts at CCHMC and to function as a nexus for coordinating multi-center pediatric AKI research. Dr. Goldstein is the Founder and Principal Investigator of the Prospective Pediatric AKI Research Group (www.ppaki.org), a 50 center international pediatric acute care nephrology research consortium that will focuses on pediatric AKI epidemiology, interventional trials, device evaluation and genetic studies. Dr. Goldstein is also the program director for the only Pediatric Acute Care Nephrology fellowship in the United States.

Theresa Mottes, MSN, RN,CPNP-AC,CDN

Theresa Mottes has over 20 years of pediatric renal replacement therapy experience is both the critical care setting and the outpatient dialysis setting. She has been involved in research with acute kidney injury, continuous renal replacement therapies and simulation based education for CRRT training. Theresa currently is a nurse practitioner for critical care nephrology. Theresa is very active with ANNA, as the current Pediatric Specialty Practice Network facilitator. She has presented at both national and international conferences.

David Selewski, MD

I am an Assistant Professor in the Department of Pediatrics within the Division of Nephrology at the University of Michigan. I received my training in pediatrics and pediatric nephrology at the University of Michigan. My clinical and research interests include pediatric critical care nephrology including pediatric & neonatal acute kidney injury, fluid overload, and continuous renal replacement therapy.
4:00-4:15
Coffee Break
4:15-4:55
Interactive Clinical Case (Decision Making)

Ashita Tolwani, MD

Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
5:00-5:30
Post Course Test and Wrap-up

Jorge Cerda, MD, MS, FACP, FASN

Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY Clinical Associate Professor of Medicine, Albany Medical College, Albany NY Fulbright Scholar, 1980 Fellow, American College of Physicians Fellow, American Society of Nephrology Organizing Committee, International Conference AKI & CRRT AKI Advisory Group, American Society of Nephrology AKI Committee, and "0by25" Initiative, International Society of Nephrology Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease Associate Editor, Blood Purification and Kidney International Reports Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world

Ashita Tolwani, MD

Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
5:30pm
Adjourn

Pre-Conference AKI Symposium

7:55-5:30
PW1 Changing Paradigms in Acute Kidney Injury:
From Mechanisms to Management

sponsored by:
The UAB-UCSD O'Brien Core Center for
Kidney Injury Research
Acute Kidney Injury is a rapidly evolving area where several advances have been made in understanding the mechanisms and pathways of AKI and its effects on other organs. Recent identification of biomarkers has provided new tools and techniques to characterize this disorder. This pre-course workshop will provide a comprehensive review of the most recent developments in the field and describe emerging knowledge from basic and translational research. Results from clinical trials will be discussed to define the best strategies for effective management of patients and define the criteria for future studies.
CRRT Conference registration is not required to attend this symposium, separate registration is available.
Room: Regatta ABC
7:55-8:00
Opening Remarks
Room: Regatta ABC

Ravindra Mehta, MBBS, MD, DM, FACP

Dr. Mehta is Professor of Medicine in the Division of Nephrology and Associate Chair for Clinical Affairs in the Department of Medicine at the University of California, San Diego (UCSD) where he directs the Clinical nephrology and dialysis programs. He is also the Chair of the International Society of Nephrology Commission on Acute Renal Failure, founding member of the Acute Dialysis Quality Initiative. He received the M.B.B.S. degree (1976) from the Government Medical School in Amritsar, India, and the M.D. (1979) and D.M. (1981) degrees from the Post Graduate Institute of Medical Education and Research in Chandigarh, India. He subsequently completed a nephrology fellowship at the University of Rochester in Rochester New York and obtained his boards in internal medicine (1986) and Nephrology (1988). He has been on the faculty at San Diego since 1988. His reserach interests are in the field of acute renal failure and he has directed several clinical studies in the management of patients with ARF including comparing different dialytic modalities, conducting large multicenter observational studies of ARF with the PICARD group, evaluating different predictive models for outcomes in ARF, investigating the role of cytokine removal by dialysis membranes in sepsis and ARF, and evaluating techniques for determining the amount of excess fluid in dialysis patients.
AKI Symposium - Plenary 1
Molecules, Mechanisms and Targets
8:00-10:00

Anupam Agarwal, MD

Anupam Agarwal, MD Professor of Medicine, Director, Division of Nephrology. Dr. Agarwal's research program has provided critical insights regarding the cytoprotective nature and significance of heme oxygenase-1 (HO-1) in vascular and renal inflammation, angiogenesis, transplant biology, and the molecular regulation of the human HO-1 gene. Dr. Agarwal's research efforts include three main areas. (i) His laboratory is studying the molecular regulation of the human heme oxygenase-1 (HO-1) gene in renal injury, transplant rejection, diabetic vascular disease and in atherosclerosis. Studies are also exploring the cellular mechanisms involved in the protective effects of the HO-1 enzyme in renal and vascular injury. Induction of this gene occurs as an adaptive and beneficial response to injury and is protective in several clinically important conditions such as acute renal failure, transplant rejection and atherosclerosis. Studies are focused on identifying regulatory regions in the human HO-1 gene that mediate induction in response to stimuli such as heme, cytokines, nitric oxide, modified lipids and growth factors (eg. transforming growth factor-beta). The studies involve molecular biology techniques to study DNA-protein interactions using chromatin structure analysis, in vivo footprinting, site-directed mutagenesis and gel shift assays. His laboratory is also studying the molecular and biological effects of nitrated lipids on HO-1 gene expression in endothelial cells and in the vasculature. (ii) The functional significance of HO-1 gene expression is also being evaluated using both in vitro and in vivo systems in transgenic animal models of acute kidney injury, immune-mediated injury in the setting of transplantation, diabetes and atherosclerosis. (iii) His laboratory is actively pursuing gene delivery approaches in the kidney and the vasculature in animal models of transplantation and diabetes using recombinant adeno-associated viral vectors. Alternate serotypes and capsid mutants of adeno-associated viral vectors are being developed to maximize gene transfer to the otherwise resistant vascular compartment with a goal towards targeting diabetic micro and macrovascular disease.

Bruce Molitoris, MD

Bruce A. Molitoris, M.D. is a Professor of Medicine, Director of Nephrology and Director of the Indiana Center for Biological Microscopy at Indiana University School of Medicine. He received his M.D. Degree from Washington University in St. Louis and his Nephrology Fellowship training at the University of Colorado. His active areas of research interest include Acute Kidney Injury, Toxic Nephropathy and Microscopic Imaging Techniques.
8:00-8:20
TGF-b in the AKI to CKD Transition

Leslie Gewin, Assistant Professor

Leslie Gewin is an Assistant Professor in the Division of Nephrology at Vanderbilt University Medical Center (VUMC) and a Staff Physician at the Nashville VA whose research interest focuses on understanding the mechanisms underlying chronic kidney disease (CKD) progression. More specifically, the Gewin laboratory focuses on renal tubule epithelial injury and how growth factors like TGF-beta and Wnt/beta-catenin modulate the proximal tubule’s responses to injury. Her lab, funded by the NIH and VA, also explores how altered epithelial metabolism and cell cycle may be adaptive versus maladaptive in the context of kidney injury. Her goal is to better understand the basic science mechanisms of renal repair to better inform future therapeutics for the progression of chronic kidney disease. Dr. Gewin attends on the general internal medicine wards and the nephrology consult service at the Nashville VA. She is co-director of the Kidney Student Research Training Program, which places medical students in labs for a mentored research experience during the summer between first and second years. She serves as a Councilor for Women in Nephrology (WIN) and co-directs a medical school course on critical appraisal of the scientific literature.
8:20-8:40
Pannexins in Acute Kidney Injury

Mark Okusa, MD

Mark D. Okusa, M.D. is the John C. Buchanan Distinguished Professor of Medicine, Chief, Division of Nephrology and Director, Center for Immunity, Inflammation and Regenerative Medicine at the University of Virginia, Charlottesville, VA. He received his M.D., and internship and residency training at the Medical College of Virginia, Richmond, VA followed by clinical and research nephrology training at Yale University, New Haven, CT. Dr. Okusa joined the faculty at the University of Virginia in 1991 as a clinician investigator combining clinical care, education and research. His clinical and research interest focus on acute kidney injury. He is the principal investigator of several NIH grants including a T32 training grant. He has published over 130 original manuscripts and book chapters. He has served on advisory committees and study sections for the NIH, ASN, AHA, and NKF and as Chair of the Program Committee of the ASN (2011). Dr. Okusa was the Associate Editor of Nephron Physiology, and Kidney International and current member of the editorial boards of the American Journal of Physiology:Renal Physiology, American Journal of Nephrology, Kidney International and Journal of the American Society of Nephrology. Dr. Okusa has been listed in Castle Connally’s America’s Top Doctors (2001-2014), member of the American Clinical and Climatological Association and elected Councilor to the American Society of Nephrology in 2012.
8:40-9:00
Single Cell Transcriptomics in AKI and CKD

Ben Humphreys, MD, PhD

Dr. Benjamin Humphreys received his AB from Harvard college and his M.D. and Ph.D. degrees from Case Western Reserve University as part of the Medical Scientist Training Program. He trained in internal medicine at Massachusetts General Hospital and in nephrology at Brigham and Women’s Hospital and Massachusetts General Hospital. He was a member of the faculty at Harvard Medical School from 2005 - 2015, rising to the rank of Associate Professor. In 2015 Dr. Humphreys moved to Washington University in St. Louis, where he is Chief of the Division of Nephrology and is the Joseph Friedman Professor of Renal Diseases. Dr. Humphreys is an internationally recognized investigator in kidney fibrosis, stem cells and regenerative medicine. Current efforts in his laboratory focus on single cell RNA-sequencing and multi-omic approaches to identify new therapeutic targets in kidney diseases.
9:00-9:20
Regulatory B Cells and Natural IgM in AKI

Peter Lobo, Professor

I was educated in Kampala Uganda in the 1960s and completed my residency at Mulago Hospital, Makerere University, Uganda in 1970. Under the direction of Dr. Edward Hook, I completed a second residency in medicine at the University of Virginia followed by a clinical fellowship in nephrology and research in immunology and transplantation. I joined the faculty in 1976 and have always been affiliated with the University of Virginia Division of Nephrology. My research in basic science has spanned from 1975 to 1988 and from 2007 to the present. During the intervening period I was asked by the Department Chair to direct the clinical renal/pancreas transplant program and increase the number of kidney transplant from 30 to more than 100 per year and to direct the Clinical Histocompatibility Laboratory. From 2005 to 2007, our Kid Tx program transplanted >100 kid/yr at which point I stepped down as director of Clinical Tx program and resumed basic research but continued directing the Histocompatibility Lab.. My research interests include transplant immunology with focus on desensitizing patients pre-transplant and investigating the role of natural IgM and ex-vivo induced Bregs in inducing transplant tolerance and preventing AKI.
9:20-9:40
The Kidney is Out of Breath in AKI

Can Ince, PhD

Short Bibliography Professor dr. Can Ince is a physiologist whose interest lies in peri-operative medicine. He heads the Department of Translational Physiology at the Academic Medical Center (AMC) of the University of Amsterdam where research is directed at cardiovascular aspects of peri-operative medicine. He is part-time staff member (40%) of the Department of Intensive Care of the Erasmus Medical Center Rotterdam (head prof Diederik Gommers). Prior to his current position he was professor of Experimental Anesthesiology at the Dept of Anesthesiology at the AMC. Before going to the AMC he was associate professor at the University Hospital of Rotterdam at the Intensive Care Unit of the Dept of General Surgery (head prof. HA Bruining). Prior to that he had worked at the Dept. of Infectious Diseases (University Hospital Leiden) for some ten years on immunological research. He has a PhD in immunology/cell physiology from the University of Leiden. He has degrees in electrical and electronic engineering (BSc University of Birmingham (UK), MSc Technical University of Delft (Netherlands). Prof Ince is past-president of the Dutch Physiological Society, former chairman of the Scientific Committee of the Netherlands Society for Intensive Care Medicine and past-president of the International Society of Oxygen Transport to Tissue.
9:40-10:00
Discussion
10:00-10:15
Coffee Break
AKI Symposium - Plenary 2
Harmonizing Human and Animal AKI: Results from ADQI 13
10:15-12:15

Paul Sanders, MD

Dr. Paul W. Sanders is Professor of Medicine and holder of the Thomas E. Andreoli Endowed Chair in Nephrology at the University of Alabama at Birmingham (UAB). He is also Chief of the Renal Section at the Birmingham Veterans Affairs Medical Center and is Director of the Nephrology Research and Training Center at UAB. After completing a residency in Internal Medicine and fellowship in Nephrology at UAB, Dr. Sanders has remained on faculty and has risen in the ranks to his present position. He has received a number of honors that include election into Alpha Omega Alpha and the American Society for Clinical Investigation. He is Fellow of the American College of Physicians and American Heart Association. His research has been funded for more than two decades by the Department of Veterans Affairs and by the National Institutes of Health. Dr. Sanders has served on numerous grant review committees for the National Institutes of Health, National Kidney Foundation, American Heart Association, American Society of Nephrology, and the Department of Veterans Affairs. He has authored 103 peer-reviewed articles and 47 book chapters and editorials that describe the vascular and renal alterations associated with dietary salt intake and the mechanism(s) of acute and chronic kidney injury induced by immunoglobulin light chains.

Volker Vallon, MD

Dr. Vallon is Professor of Medicine and Pharmacology at UCSD and a principal investigator at the VA San Diego Healthcare System. He received his M.D. from the University of Tuebingen, Germany, in 1992, and research training at the University of Tuebingen, UCSD, and the NIH. He joined the faculty at the University of Tuebingen in 1998, and at UCSD in 2003. His group has characterized the roles played by a variety of channels, transporters, receptors and signaling molecules in the physiology, pathophysiology, and pharmacology of the kidney. He aims to integrate aspects of vascular, glomerular and tubular function to gain a more complete understanding of the physiology and pharmacology of the kidney as well as the pathophysiology of acute kidney injury, arterial hypertension and the diabetic kidney.
10:15-10:35
Molecular Characterization of the Transition from AKI to CKD

Andrew McMahon, PhD

10:35-10:55
Impact of Metabolism on Surviving Sepsis: Implications for Sepsis-induced AKI

Sarah Huen, MD, PhD

Sarah Huen, M.D., Ph.D., is an Assistant Professor at the University of Texas Southwestern Medical Center in the Departments of Internal Medicine (Nephrology) and Pharmacology. Dr. Huen received her medical degree from Northwestern University. She completed Internal Medicine residency training at New York University Medical Center and Nephrology fellowship training at Yale University. She then completed a Ph.D. program in Investigative Medicine at Yale in the laboratory of Dr. Lloyd Cantley studying the role of macrophages in ischemic kidney injury. As a post-doctoral fellow in the laboratory of Dr. Ruslan Medzhitov at Yale, Dr. Huen investigated the metabolic requirements of tissue tolerance in bacterial and viral inflammation. Dr. Huen joined the faculty at UT Southwestern in 2017. Dr. Huen’s research interests include investigating renal metabolism in sepsis. She is also exploring the role of fasting metabolism in disease states associated with anorexia and cachexia.
10:55-11:15
HDAC Inhibition for Prevention of Fibrosis Following Sepsis-induced AKI

John Kellum, MD

John A. Kellum, MD, FACP, MCCM John A. Kellum, MD, MCCM is Professor of Critical Care Medicine, Medicine, Bioengineering and Clinical and Translational Science, and Vice Chair for Research within the Department of Critical Care Medicine and Director of the Center for Critical Care Nephrology at the University of Pittsburgh. Dr. Kellum received his medical degree from the Medical College of Ohio in 1984. His postgraduate training includes an internship and residency in Internal Medicine at the University of Rochester, NY, and a Fellowship in Critical Care Medicine at the University of Pittsburgh Medical Center. Dr. Kellum is actively involved in education, research and administration. Dr. Kellum’s research interests span various aspects of Critical Care Medicine, but center in critical care nephrology, sepsis and multi-organ failure, and clinical epidemiology, including consensus development and research methodology. He has authored more than 250 publications and has won several awards for teaching. He lectures widely and has given more than 300 seminars and invited lectures worldwide related to his research.
11:15-11:35
Epigenetic Regulation in AKI

Zheng Dong, PhD

Dr. Dong is Regents’ Professor at Medical College of Georgia of Georgia Regents University. He is also a Senior Research Career Scientist and Director of Research Development at the Charlie Norwood VA Medical Center. His research revolves around the regulation of cell injury/death, its protection, and subsequent recovery or regeneration during acute kidney injury and cancer therapy. His current interest is in the areas of mitochondrial dysfunction, autophagy, microRNA, and cell cycle regulation. He has published over 150 articles in regarded journals. He currently serves on the editorial boards of 7 journals including Kidney International and American Journal of Physiology-Renal Physiology. His research has been recognized by the Senior Career Scientist award from VA, Carl W. Gottschalk Scholarship from the American Society of Nephrology and Lyndon B. Johnson Research Award from American Heart Association.
11:35-11:55
Renin-Angiotensin-Aldosterone System: Good for the Kidney

Matthieu LeGrand, Pr

Pr Matthieu Legrand is Professor of Anesthesiology and Critical care medicine. He holds a PhD in physiology. He Works in the Department of anesthesiology, Critical care and burn unit of St-Louis hospital, university Paris Diderot, France. He has carried preclinical and clinical research in the field of critical care medicine with a special interest in critical care nephrology, sepsis and in burn critical care. He has served as a reviewer for several peer-review journals and expert in the field of critical care for several commitees and task forces.
11:55-12:15
Discussion
12:15-1:15
Lunch Hosted by Conference for Workshop Participants
AKI Symposium - Plenary 3
Bench to Bedside: Translating Discoveries to Clinical Care
1:15-3:15

Kathleen Liu, MD, PhD, MAS

Kathleen D. Liu, MD, PhD, MAS is a Professor in the Departments of Medicine and Anesthesia, Divisions of Nephrology and Critical Care Medicine at the University of California, San Francisco. Dr. Liu graduated from the University of California, San Francisco and trained as a resident at the Brigham and Womens Hospital in Boston. She trained in nephrology and critical care at the University of California, San Francisco. She is board-certified in both nephrology and critical care. Her research interests include biomarkers of kidney disease, acute kidney injury and acute lung injury.

Patrick Murray, Prof

Patrick Murray is Professor of Clinical Pharmacology in University College Dublin, and a consultant physician (clinical pharmacologist & nephrologist) at the Mater Misericordiae University Hospital, Dublin, Ireland. He received his medical education at University College Dublin, Ireland. Following his internship at the Mater Misericordiae University Hospital in Dublin, he completed a residency in internal medicine at Hennepin County Medical Center in Minneapolis, Minnesota, USA. He completed fellowship training programs in nephrology, critical care medicine, and clinical pharmacology at the University Of Chicago Hospitals in Chicago, Illinois, USA. He is board-certified in nephrology, critical care medicine, and clinical pharmacology. He practiced as an intensivist, nephrologist, and clinical pharmacologist at the University of Chicago Hospitals from 1996–2008, serving as the fellowship training program director in nephrology, also directing the Acute Dialysis Service. He has a longstanding interest in research and education to improve the prevention, diagnosis, and therapy of acute kidney injury and nephrotoxicity, and the pharmacotherapy of patients with kidney disease. He is a member of several international consensus groups that have produced guidelines for research and practice in the field of acute kidney injury (ADQI, AKIN, KDOQI). Since 2008, he has been the Professor of Clinical Pharmacology at University College Dublin, and a Consultant in Nephrology & Clinical Pharmacology at the Mater Misericordiae University Hospital. He is Chair of the Mater Misericordiae University Hospital Drugs & Therapeutics Committee. He is the Clinical Director of the UCD-Mater Clinical Research Centre. In 2011, he was appointed Associate Dean for International Affairs in the UCD School of Medicine and Medical Science. In 2012, he was appointed Director of the Dublin Centre for Clinical Research (DCCR) Consortium Network, and also Clinical Director of the Irish Clinical Research Infrastructure Network (ICRIN). Since December 2012, he has been the Dean and Head of the School of Medicine at UCD.
1:15-1:35
Successfully Testing AKI Therapies in CKD Models

Bruce Molitoris, MD

Bruce A. Molitoris, M.D. is a Professor of Medicine, Director of Nephrology and Director of the Indiana Center for Biological Microscopy at Indiana University School of Medicine. He received his M.D. Degree from Washington University in St. Louis and his Nephrology Fellowship training at the University of Colorado. His active areas of research interest include Acute Kidney Injury, Toxic Nephropathy and Microscopic Imaging Techniques.
1:35-1:55
Metabolic Stress in AKI: From Mouse to Man

Samir Parikh, MD

Samir M. Parikh, MD Assistant Professor of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School Samir Parikh serves as a staff physician in the Division of Nephrology at Beth Israel Deaconess Medical Center and as a principal investigator with joint affiliations in the Division of Nephrology and the Center for Vascular Biology Research. His laboratory has described Tie-2 related mechanisms of vascular leak in sepsis, and more recently, systemic anthrax and idiopathic capillary leak syndrome. He also directs human subject-based studies to evaluate the diagnostic and prognostic value of measuring soluble proteins that signal the endothelium in sepsis, in particular Angiopoietin-2. His laboratory is also engaged in understanding the parenchymal response to sepsis-induced microvascular injury where they have focused on the role of PGC-1α as a mediator of mitochondrial biogenesis. Dr. Parikh graduated magna cum laude from Harvard with a degree in chemistry and received the Founder’s Medal from Vanderbilt University School of Medicine. He completed post-graduate medical training at Beth Israel Deaconess Medical Center and Harvard Medical School. His laboratory has been awarded research grants from the NIDDK, NHLBI, American Society of Nephrology, American Heart Association, and American Diabetes Association.
1:55-2:15
Tubular Health Characterization in AKI

Etienne Macedo, MD, PhD, FASN

Etienne Macedo graduated from the University of Sao Paulo (USP) in Sao Paulo, Brazil. She completed her residency and fellowship through the USP Hospital das Clinicas, and her post-doctorate at the University of California, San Diego, where she continues to work as a clinician and researcher in AKI.
2:15-2:35
AKI in Kidney Transplants: New Insights

Roslyn Mannon, Dr.

Dr. Roslyn Bernstein Mannon is a Professor of Medicine and Surgery, and Director of Transplant Research at the University of Alabama at Birmingham. Dr. Mannon received her MD from Duke University School of Medicine, completed her Internal Medicine and Nephrology training at Duke, and was the Chief Medical Resident. Her laboratory research focuses on mechanisms of chronic graft injury using in vitro and rodent models of kidney transplantation and CNI nephrotoxicity. She is site PI for the NIH/NIAID Clinical Trials in Organ Transplantation, and a member of the CTOT Steering Committee. She has published over 100 peer reviewed publications on the mechanisms of chronic allograft injury, ischemic injury following organ procurement, and other medical complications after transplantation. She was a past-president of AST. Dr. Roslyn B Mannon, a past-president of AST, is a Professor of Medicine and Director of Research for the Comprehensive Transplant Institute at UAB. A graduate of Duke University Medical School, she completed Internal Medicine and Nephrology training at Duke. Her laboratory research focuses on mechanisms of chronic graft injury using in vitro and rodent models of kidney transplantation and CNI nephrotoxicity. She is site PI for the Clinical Trials in Organ Transplantation, and a member of the CTOT Steering Committee. She has published over 100 peer reviewed publications on the mechanisms of chronic allograft injury and therapeutics in transplantation
2:35-2:55
Renal Injury During Preclampsia: Role of Extracellular Vesicles

Vincenzo Cantaluppi, MD

Vincenzo Cantaluppi is Associate Professor of Nephrology at tbe University of Eastern Piedmont “A. Avogadroâ€, “Maggiore della Carità†University Hospital in Novara, Italy. He is the Director of Nephrology and Kidney Transplantation Unit at the University of Eastern Piedmont. He is an active clinical investigator in the fields of acute kidney injury, renal replacement therapy in intensive care unit, kidney transplantation. His main lines of basic research are focused on acute kidney injury biomarkers and on development of new potential therapeutic strategies for acute kidney injury based on transplantation of stem cells and derived extracellular vesicles.
2:55-3:15
Discussion
3:15-3:30
Coffee Break
AKI Symposium - Plenary 4
Controversies in AKI
3:30-5:30

Stuart Goldstein, MD

Dr. Goldstein serves as Director for the Center for Acute Care Nephrology (CACN) at Cincinnati Children's Hospital Medical Center. The CACN's mission is to coordinate all AKI related clinical, research and outcomes efforts at CCHMC and to function as a nexus for coordinating multi-center pediatric AKI research. Dr. Goldstein is the Founder and Principal Investigator of the Prospective Pediatric AKI Research Group (www.ppaki.org), a 50 center international pediatric acute care nephrology research consortium that will focuses on pediatric AKI epidemiology, interventional trials, device evaluation and genetic studies. Dr. Goldstein is also the program director for the only Pediatric Acute Care Nephrology fellowship in the United States.

Claudio Ronco, MD

Actual Position:
Dr. Claudio Ronco
Director
Department of Nephrology
St. Bortolo Hospital
Viale Rodolfi 16
I-36100 Vicenza
Italy

Name: Claudio Ronco

Date of birth: July 12, 1951

Education: High School Diploma at Vicenza Classic Lyceum “A.Pigafetta” in 1970 with the score: 45/60. Dr. Ronco Graduated in Medicine at University of Padua in 1976 with the score 110/110 and merit debating an experimental thesis on title “ Aspects of the Nitrogen metabolism in the nephrotic syndrome”.
From 1973 to 1976 has been intern at Institute of Clinical Internal Medicine I^ of the University of Padua, directed by Prof. E. Fiaschi, in the Nephrology Department II, under the supervision of the Prof. G. Maschio.

Postgraduate training: From July 1976 to November 1977 he has been internal resident at the Division of Internal Medicine of the St. Bortolo Hospital in Vicenza, directed by Prof. D. Corà.
In 1979 he has achieved the Specialization Diploma on Medical Nephrology at The postgraduate school of internal medicine of the University of Padua, with the score 70/70 debating a thesis on the “new methodologies for the measurement of the urinary bicarbonate”
In 1989 he has achieved the Diploma of Specialization in Pediatric Nephrology at University of Naples.
1982: Visiting Fellow at the Mount Sinai Hospital in New York, Department of Internal medicine, Nephrology Division, for four months. He carried out studies on hemofiltration and glomerular filtration with J.P. Bosh, S. Glabman and M. Levitt.
1984: Visiting Physician at the Mount Sinai Hospital In New York for two weeks and at VA Hospital in Los Angeles for two weeks.
1985: Visiting professor at the Nephrology Division of the George Washington University Hospital, Washington DC, and NIH at National Naval Medical Center of Bethesda for three months.
1988: Visiting professor at the Renal and Hypertension Division of George Washington University for three months.
1991: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
1995: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.

Teaching acitivity and Academic Qualifications: From 1978 to 1984 he has been in charge of the teaching program of Nephrology and Dialysis at Professional Nursing School in Vicenza.
During the academic years 1989-01 he has been in charge of teaching “Dialytic therapy” at Specialization School in Medical Nephrology of Padua University where he holds a post of Professor of Nephrology in charge of the teaching program concerning Hemodialysis and renal replacement therapies in critically ill patients.
October 1999-December 2000: Professor of Medicine at Albert Einstein College of Medicine and Director of the Renal laboratory at the Beth israel Medical Center in New York.
In the last ten years Professor Ronco was asked to deliver lectures and seminars in several Universities.
He has delivered in meetings and seminars more than 300 lectures and presentations.

In 1982 he introduced in Italy the use of continuous hemofiltration and in 1986 he published the first series of neonates treated with arteriovenous hemofiltration.
In 1985 He contributed to the introduction in Europe of high flux dialysis and derived therapies. He also established the dangerous effect of backfiltration in a contaminated dialysis fluid condition.
He has conducted a series of clinical and experimental researches in the following fields:
- Kinetics of fluid and solute removal in peritoneal dialysis and hemodialysis
- Treatment of Acute renal failure with intermittent and continuous therapies
- Renal replacement therapy in the neonate
- Development of new treatment modalities for acute and chronic renal failure.
- Studies on biomaterials
- Studies on glomerular filtration in humans and renal functional reserve
- Renal physiology in pregnancy
- Hydraulics and flow dynamics in the extracorporeal circulation
- Adequacy of dialysis
- Acid-Base Balance in uremia and dialysis
- Acute renal failure and Critical Care Nephrology

Professional employement and Hospital appointments:
Assistant of clinical nephrology from 1977 to 1984 at Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Associate of clinical nephrology from 1984 at Department of Nephrology , St. Bortolo Hospital, Vicenza, Italy.
From 1984 he is director of the hemodialysis and peritoneal dialysis center of the Department of Nephrology at St. Bortolo Hospital, Vicenza, Italy.
From October 25, 1999 to December 1st 2000 Dr. Ronco has been Director of the research laboratory of Hemodialysis at the Beth Israel Medical center of New York and Visiting Professor of Medicine at the Albert Einstein College of Medicine of new York
Today Dr. Ronco is director of the Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.

Board certification: In 1989 he has achieved in Rome, the National License for Nephrology Chair and Directional Functions, with the score 94/100.

Professional Society Membership: He is mamber of the council of several scientific societies and he is editor in chief of the international journal of artificial organs and contributions to nephrology.

Awards and honors:
1983 Schwartz Award, for the best paper of the year at St. Bortolo Hospital.
1984 G.F. Volpato Grant for the best research project on acute renal failure in Italy
1989 Best paper Prize at the Italian Society of nephrology meeting.
1991 ESAO RESEARCH AWARD for the best paper presented at the European Society for Artificial Organs.
1996 Arturo Borsatti Award of Padova University as a best nephrologist of the year.
2004 Lifetime achievement award

Other professional activities: He has organized several congresses and meetings in the area of nephrology and Intensive care from 1982 to today.
He is member of several advisory groups for clinical trials and dialysis research.

Lectures and publications: Dr. Ronco has coauthored 560 papers, 36 book chapters, 26 books, 7 monographic journal issues and has delivered more than 300 lectures in international meetings and universities. His personal impact factor calculated at december 2002 is 391.
3:30-3:50
AKI following Cardiac Surgery: A Clinical Model

Frederic Billings, MD, MSc

Frederic T. (Josh) Billings IV, MD, MSc, is associate professor of anesthesiology and medicine in the division of anesthesiology critical care medicine in the Department of Anesthesiology at Vanderbilt University. His research program focuses on mechanisms of surgery-induced organ injury, specifically the impact of perioperative oxidative damage on kidney, brain, and heart injury, and developing new therapy for perioperative organ injury in humans. He co-directs the B.H. Robbins Scholars Program, the Department’s physician-scientist development program, and clinically cares for patients undergoing cardiothoracic surgery and attends in the cardiovascular ICU.
3:50-4:10
Renal Immune Surveillance in AKI

Daniel Muruve, MD

Dr. Muruve has already sent this Thank you
4:10-4:30
Remote Ischemic Preconditioning: Fact or Fantasy?

Alex Zarbock, MD

Dr. Zarbock is a Clinician Scientist and the Director and Chair of the Department of Anesthesiology and Critical Care Medicine, at the University of Münster, Germany. He acquired training at the University of Münster (Anesthesiology and Critical Care Medicine). Dr. Zarbock is supported by the German Research Foundation. His research interests span various aspects of Critical Care Medicine, but center in critical care nephrology (renal replacement therapy), sepsis and organ protection. Dr. Zarbock’s current projects include measures to avoid acute kidney injury after surgery and the timing of renal replacement therapy in critically ill patients with acute kidney injury. He is also author and co-author of over 140 scientific articles and book chapters.
4:30-4:50
Targeting AKI Using Biomarker Combinations

Rajit Basu, MD MS FCCM

Dr. Basu is dedicated to improving the recognition, treatment, and outcomes of critically ill children suffering acute kidney injury. As Co-Director of the Center for Acute Care Nephrology at Cincinnati Children's Hospital, Dr. Basu oversees projects in the pediatric intensive care unit investigating AKI prediction by risk stratified optimization of biomarkers (renal angina), biomarker and fluid overload directed renal replacement therapy initiation, and use of the EMR to provide clinical decision support for management of AKI and fluid balance. Prior to arriving at Cincinnati Children's in 2009, Dr. Basu completed his Pediatric Critical Care fellowship and Pediatric residency at Northwestern University in Chicago. Originally from South Bend, Indiana, he is a graduate of Indiana University Medical School and the University of Notre Dame (undergraduate degree in Biochemistry).
4:50-5:10
Phenotyping Acute Kidney Disease - ATN vs. AIN?

Chirag Parikh, MD, PhD

Chirag R. Parikh, MD, PhD, FACP, FASN, is an Associate Professor of Medicine in the Section of Nephrology, Associate Professor of Investigative Medicine, and Director, Program of Applied Translational Research, at Yale University School of Medicine. He is also an Associate Professor in the Clinical Epidemiology Research Center at the VA Connecticut Health Care System. His principal research interests focus on the translation and validation of novel biomarkers for the diagnosis and prognosis of acute kidney injury. Dr. Parikh completed the largest validation study of urinary biomarkers in which more than 10,000 samples were collected for the measurement of biomarkers for early diagnosis and prognosis of AKI after cardiac surgery. In 2005, he founded TRIBE-AKI (Translational Research Investigating Biomarker Endpoints in AKI)—a consortium of researchers across several states which have enrolled over 2500 patients in three cohort studies. TRIBE-AKI has yielded groundbreaking, nationally recognized achievements in biomarker discovery and validation, and its success led to establishment of the Program of Applied Translational Research in 2012. The program is comprised of a multidisciplinary team of talented physicians and scientists committed to patient-oriented research and improved outcomes in clinical medicine and disease management. As Director of PATR, Dr. Parikh oversees several NIH-sponsored, multicenter studies testing biomarkers in the areas of cardiac surgery, kidney transplantation, aging, HIV, and hepatorenal syndrome.
5:10-5:30
Discussion
5:30pm
AKI Workshop Adjourns
5:30-7:30pm
Reception and Poster Review
For All Conference Attendees

Wednesday, Morning February 27

7:00am
Conference Registration Open
7:00-8:15
ME1 MEET THE EXPERT
How I Treat Septic Shock

Kathleen Liu, MD, PhD, MAS

Kathleen D. Liu, MD, PhD, MAS is a Professor in the Departments of Medicine and Anesthesia, Divisions of Nephrology and Critical Care Medicine at the University of California, San Francisco. Dr. Liu graduated from the University of California, San Francisco and trained as a resident at the Brigham and Womens Hospital in Boston. She trained in nephrology and critical care at the University of California, San Francisco. She is board-certified in both nephrology and critical care. Her research interests include biomarkers of kidney disease, acute kidney injury and acute lung injury.

John Louis Vincent, MD PhD

Professor Vincent is Professor of intensive care medicine at the University of Brussels (Université Libre de Bruxelles) and intensivist in the Department of Intensive Care at Erasme University Hospital in Brussels. He obtained his PhD degree at the University of Brussels in 1982. He is a Past-President of the World Federation of Societies of Intensive and Critical Care Medicine (WFSICCM), the European Society of Intensive Care Medicine (ESICM), the European Shock Society (ESS), the Belgian Society of Intensive Care Medicine (SIZ), and the International Sepsis Forum (ISF). He was a Council member of the Society of Critical Care Medicine (SCCM) from 2011-2013. He is member of the Belgian Royal Academy of Medicine. Dr. Vincent has signed more than 900 original articles, some 400 book chapters and review articles, 1000 original abstracts, and has edited 102 books. He is co-editor of the “Textbook of Critical Care†(Elsevier Saunders) and the “Encyclopedia of Intensive Care Medicine†(Springer). He is the editor-in-chief of Critical Care, Current Opinion in Critical Care, and ICU Management & Practice and member of the editorial boards of about 30 other journals, including Critical Care Medicine (senior editor), the American Journal of Respiratory and Critical Care Medicine (AJRCCM), PLoS Medicine, Lancet Infectious Diseases, Intensive Care Medicine, Shock, the Journal of Critical Care and Annals of Intensive Care. Dr Vincent has received several awards including the College Medalist Award of the American College of Chest Physicians, the Society Medal (lifetime award) of the European Society of Intensive Care Medicine,), the distinguished investigator Award and the Lifetime Achievement Award of the Society of Critical Care Medicine, and the prestigious Belgian scientific award of the FRS-FNRS (Prix Scientifique Joseph Maisin-Sciences biomédicales cliniques). His name appears more than 1000 times in Pubmed, and his work has been cited more than 140,000 times; his H-index is 156. In recognition for these achievements, he was awarded the title of Baron by King Albert II of Belgium in 2013.
7:00-8:15
ME2 MEET THE EXPERT
How do I Manage the Fluid Overloaded Patient?

Sean Bagshaw, MD, MSc, FRCPC

Dr. Bagshaw is a Clinician Scientist and Assistant Professor in the Division of Critical Care Medicine, at the University of Alberta in Edmonton, Alberta, Canada. He acquired training at the University of Calgary (Internal Medicine, Critical Care Medicine, Masters of Science Epidemiology) prior to completing a critical care nephrology fellowship in the Department of Intensive Care Medicine, at the Austin Hospital in Melbourne, Australia. Dr. Bagshaw is supported by a Canada Research Chair in Critical Care Nephrology and a Clinical Investigator Award from Alberta Innovates - Health Solutions. Dr. Bagshaw's main research interests have focused on the clinical, epidemiological and translational issues related to acute kidney injury and the application of extracorporeal blood purification in critically ill patients. Dr. Bagshaw's current projects include diuretic therapy in early acute kidney injury and factors related with the initiation of renal support in critically ill patients. He has published over 100 peer-reviewed papers, numerous book chapters, and peer-reviewed for over 20 medical journals. Dr. Bagshaw is a member of several organizations including the Canadian Critical Care Society, Canadian Critical Care Trials Group, Australia New Zealand Intensive Care Society, and the Acute Kidney Injury Network, and the Acute Dialysis Quality Initiative.

Stuart Goldstein, MD

Dr. Goldstein serves as Director for the Center for Acute Care Nephrology (CACN) at Cincinnati Children's Hospital Medical Center. The CACN's mission is to coordinate all AKI related clinical, research and outcomes efforts at CCHMC and to function as a nexus for coordinating multi-center pediatric AKI research. Dr. Goldstein is the Founder and Principal Investigator of the Prospective Pediatric AKI Research Group (www.ppaki.org), a 50 center international pediatric acute care nephrology research consortium that will focuses on pediatric AKI epidemiology, interventional trials, device evaluation and genetic studies. Dr. Goldstein is also the program director for the only Pediatric Acute Care Nephrology fellowship in the United States.
The Breakfast Symposia listed below are hosted by Conference (RSVP Required)
Selection made during registration
Breakfast Symposia
7:00-8:15
7:00-8:15
Breakfast Symposium A
Drug Induced Kidney Injury in the Critically Ill Patient
CME Available
Patients in the ICU are exposed to several different drugs to treat the underlying disease and support organ function. This symposium will highlight the practical aspects of drug handling in critically ill patients and illustrate how patients should be evaluated for risk for drug induced kidney injury, how should they be dosed and monitored for adjustments in drug dosing.
Awdishu (Moderator), Murray and Joy (Discussants)

Linda Awdishu, PharmD, MAS

Linda Awdishu earned her Bachelors of Science in Pharmacy from the University of Toronto in 1999, Doctor of Pharmacy from the University of Colorado in 2008 and Masters of Clinical Research from the University of California in 2007. She is an Associate Clinical Professor of Pharmacy and Medicine at UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences. She maintains a clinical practice in the chronic kidney disease program. Her research program is focused on drug induced kidney injury.

Melanie Joy, PharmD, PhD

Dr. Joy is an accomplished translational researcher having spent the last 24+ years as a researcher and clinician in nephrology, pharmacology, and pharmaceutics. Dr. Joy spent the last ~6 years at the University of Colorado and is now a tenured Associate Professor in the Skaggs School of Pharmacy and Pharmaceutical Sciences, with a joint appointment in the School of Medicine Division of Nephrology. Previously, Dr. Joy spent 16 years at the University of North Carolina (UNC) where she was an Associate Professor of Medicine (Nephrology) and Pharmacy. Dr. Joy has consulted with numerous pharmaceutical companies on study design and has served on pharmaceutical advisory boards. Dr. Joy has conducted over 60 studies (NIH, foundation, and pharmaceutical company funded) investigating new drugs and devices in the kidney disease population and was Director of the UNC Nephrology Clinical Trials program from 1998 to 2003. She has subsequently focused on her investigator initiated and NIH funded research. Her lab is currently funded by two NIH R01 grants. Dr. Joy has published 86 articles, 21 book chapters, and over 90 abstracts. Dr. Joy is experienced in the conduct of renal pharmacology studies related to acute and chronic kidney diseases. Dr. Joy has led and managed a chronic kidney disease clinic that focused on the treatments of kidney disease complications including phosphorus management and anemia. Professional activities have included US FDA Cardiovascular and Renal Drugs Advisory Committee Member, USP Nephrology and Urology Expert Committee member, NIH NIDDK Ad Hoc reviewer for numerous study sections, several American Society of Nephrology committees and initiatives, a Kidney Health Initiative (KHI) stakeholder, American College of Clinical Pharmacy (ACCP) Leadership Institute, and UNC Mid-Career Leadership Initiative. Dr. Joy has extensive connections to clinicians, researchers, industry, and professional organizations in the nephrology area.

Patrick Murray, Prof

Patrick Murray is Professor of Clinical Pharmacology in University College Dublin, and a consultant physician (clinical pharmacologist & nephrologist) at the Mater Misericordiae University Hospital, Dublin, Ireland. He received his medical education at University College Dublin, Ireland. Following his internship at the Mater Misericordiae University Hospital in Dublin, he completed a residency in internal medicine at Hennepin County Medical Center in Minneapolis, Minnesota, USA. He completed fellowship training programs in nephrology, critical care medicine, and clinical pharmacology at the University Of Chicago Hospitals in Chicago, Illinois, USA. He is board-certified in nephrology, critical care medicine, and clinical pharmacology. He practiced as an intensivist, nephrologist, and clinical pharmacologist at the University of Chicago Hospitals from 1996–2008, serving as the fellowship training program director in nephrology, also directing the Acute Dialysis Service. He has a longstanding interest in research and education to improve the prevention, diagnosis, and therapy of acute kidney injury and nephrotoxicity, and the pharmacotherapy of patients with kidney disease. He is a member of several international consensus groups that have produced guidelines for research and practice in the field of acute kidney injury (ADQI, AKIN, KDOQI). Since 2008, he has been the Professor of Clinical Pharmacology at University College Dublin, and a Consultant in Nephrology & Clinical Pharmacology at the Mater Misericordiae University Hospital. He is Chair of the Mater Misericordiae University Hospital Drugs & Therapeutics Committee. He is the Clinical Director of the UCD-Mater Clinical Research Centre. In 2011, he was appointed Associate Dean for International Affairs in the UCD School of Medicine and Medical Science. In 2012, he was appointed Director of the Dublin Centre for Clinical Research (DCCR) Consortium Network, and also Clinical Director of the Irish Clinical Research Infrastructure Network (ICRIN). Since December 2012, he has been the Dean and Head of the School of Medicine at UCD.
7:00-8:15
Breakfast Symposium B
Therapeutic Challenges in AKI and CKD: Managing Hypo and Hyperkalemia
CME Available
This symposium will cover the pathophysiology and management of hypo and hyperkalemia in critically ill patients using illustrative cases. What are the newer therapeutic drugs available and how should they be used When and how should RRT be used in these situations?
Wald (Moderator), Qian and Lewington (Discussants)

Andrew Lewington, MD

Dr Andrew Lewington studied medicine as an undergraduate in London before pursuing a career in renal medicine. He studied in Leicester UK and Washington University USA where he worked in Mark Hammermann's laboratory investigating the molecular mechanisms underlying ischaemic acute kidney injury.Dr Lewington was appointed consultant renal physician/honorary senior lecturer at Leeds Teaching Hospitals in 2004. He works as an NHS clinician providing a specialist renal opinion on acutely ill patients on the ICU across Leeds. He was an expert adviser on the UK NCEPOD adding insult to injury AKI study, working from his position on the Renal Association executive committee to improve the care that patients who develop AKI receive. He is the lead author of the 5th Renal Association AKI clinical practice guidelines. During his time in Leeds he has developed collaborative research with an internationally recognised proteomics group. He currently has a nephrology fellow investigating potential proteomic biomarkers of kidney dysfunction in the early phase following kidney transplantation. He is Clinical Sub Dean for the Leeds Teaching Hospitals and is heavily involved in the delivery of undergraduate medical education at the University of Leeds.

Qi Qian, MD

Dr. Qi Qian is a faculty nephrologist and Professor of Medicine and Professor of Physiology at the Mayo Clinic College of Medicine and Mayo Graduate School, USA. She is the Director of the Mayo Clinic Rochester Nephrology Hospital Practice. She is also an adjunct Professor of Medicine at four top universities in China (Nanjing University School of Medicine in Nanjing, Fourth Military Medical University in Xi’an, Zhejiang University in Hangzhou, and Fudan University, Shanghai, China) A graduate of the Shanghai 2nd Medical University, Dr. Qian received her post-graduate training in medicine and nephrology at the Albert Einstein College of Medicine, Bronx, New York and was recruited to join the staff at Mayo Clinic upon her graduation from fellowship training in 1999. Dr. Qian's professional focus is on patient care, clinical/translational research and education in the area of renal tubular disorders. In the years of 2000-2008, she conducted basic science research on the renal/vascular pathophysiology through funding from Mayo Clinic Foundation and the National Institutes of Health (NIH-NIDDK). Her expertise in renal and vascular physiology and pathophysiology adds an important dimension to her management of patients with renal tubular diseases. Dr. Qian also heads the Mayo Clinic Acid-Base Electrolyte Interest Group. She is the principal investigator on a number of studies investigating the effects of electrolyte alterations and renal tubular function. Dr. Qian is an award-winning educator at Mayo Clinic. She has mentored a large number of trainees and is an author and content expert for “AskMayoExpertâ€, a popular Mayo Clinic web-based medical practice reference for clinicians all over the United States. She currently serves as the president of the Chinese American Society of Nephrology and an ISN Educational Ambassador.

Ron Wald, MD

Ron Wald is a nephrologist at St. Michael's Hospital in Toronto and an Associate Professor of Medicine at the University of Toronto. His primary research interest is in critical care nephrology and he has been involved in several clinical trials in this area. He is currently co-leading an international randomized controlled trial on the timing of renal replacement therapy in acute kidney injury. Ron also has an interest in the care provided to patients who survive an episode of acute kidney injury and has conducted research using large administrative datasets to study this population. He is co-leading a clinical trial comparing post-discharge follow-up with a nephrologist vs usual care after an episode of severe acute kidney injury.

SESSION I: PATIENT CHARACTERISTICS

Plenary 1 MINI-SYMPOSIA
Organ Dysfunction in the Critically Ill Patient: Emerging Concepts
8:20-10:30

Noel Gibney, MB FRCP(C)

Current Position: Professor, Department of Critical Care Medicine,Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada. Medical School: University College Dublin, Ireland Internal Medicine/Nephrology: St. Vincents Hospital, Dublin, Ireland Pulmonary Medicine: University of Alberta, Edmonton, AB, Canada Critical Care Medicine: Harvard University, Cambridge, MA, USA Interests: CRRT, Sepsis, Information Technology

Kathleen Liu, MD, PhD, MAS

Kathleen D. Liu, MD, PhD, MAS is a Professor in the Departments of Medicine and Anesthesia, Divisions of Nephrology and Critical Care Medicine at the University of California, San Francisco. Dr. Liu graduated from the University of California, San Francisco and trained as a resident at the Brigham and Womens Hospital in Boston. She trained in nephrology and critical care at the University of California, San Francisco. She is board-certified in both nephrology and critical care. Her research interests include biomarkers of kidney disease, acute kidney injury and acute lung injury.
8:20-8:30
Opening Remarks
Room: Coronado Ballroom

Ravindra Mehta, MBBS, MD, DM, FACP

Dr. Mehta is Professor of Medicine in the Division of Nephrology and Associate Chair for Clinical Affairs in the Department of Medicine at the University of California, San Diego (UCSD) where he directs the Clinical nephrology and dialysis programs. He is also the Chair of the International Society of Nephrology Commission on Acute Renal Failure, founding member of the Acute Dialysis Quality Initiative. He received the M.B.B.S. degree (1976) from the Government Medical School in Amritsar, India, and the M.D. (1979) and D.M. (1981) degrees from the Post Graduate Institute of Medical Education and Research in Chandigarh, India. He subsequently completed a nephrology fellowship at the University of Rochester in Rochester New York and obtained his boards in internal medicine (1986) and Nephrology (1988). He has been on the faculty at San Diego since 1988. His reserach interests are in the field of acute renal failure and he has directed several clinical studies in the management of patients with ARF including comparing different dialytic modalities, conducting large multicenter observational studies of ARF with the PICARD group, evaluating different predictive models for outcomes in ARF, investigating the role of cytokine removal by dialysis membranes in sepsis and ARF, and evaluating techniques for determining the amount of excess fluid in dialysis patients.
8:30-8:45
Hemodynamics of the Septic Kidney

Matthieu LeGrand, Pr

Pr Matthieu Legrand is Professor of Anesthesiology and Critical care medicine. He holds a PhD in physiology. He Works in the Department of anesthesiology, Critical care and burn unit of St-Louis hospital, university Paris Diderot, France. He has carried preclinical and clinical research in the field of critical care medicine with a special interest in critical care nephrology, sepsis and in burn critical care. He has served as a reviewer for several peer-review journals and expert in the field of critical care for several commitees and task forces.
8:45-9:00
The Kidney in Heart Failure: Victim or Culprit?

Salvatore diSomma, Professor of Medicin

Name: Salvatore Surname: Di Somma Place and date of birth: Naples (Italy), 7.6.1953. Graduate in Medicine “cum laude†(University of Naples), 1978. Post Graduate “cum Laude†in Internal Medicine (University of Naples), 1983. Post Graduate “cum Laude†in Cardiology (University of Naples), 1987. Current Position Professor of Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome, Department of Medical-Surgery Sciences and Translational Medicine since 2002. Chairman Postgraduate School of Emergency Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome, since 2002. Professor Postgraduate Schools of Internal Medicine and Cardiovascular Diseases Academic Positions Research Fellow - Department of Clinical and Experimental Medicine ’University “Federico II†of Naples from 1978 to 2001. Assistant Professor – Emergency Medicine and Cardioangiology – University Federico II of Naples, from 1978 al 2001. Research Fellow in Cardiology University of Pavia, 1989-1992. Assistant Professor Department of Medicine New York Medical College New York U.S.A. 1994-1996 Cardiovascular Research Institute. Minisrty of Health World Class Professor Programme , Brawijaya University Malang(Indonesia) Expert Professor in Medicinea and Cardiovascular Prevention;University of Lund (Malmoe (Sweden) Visiting Professor-Scholar Researcher -UCSD University California San Diego(USA) Scientific Societies Membership President of GREAT Network Italy President Scientific Committee of AISC (Italian Association of Patients with Heart Failure) Former President of GREAT Global Research on Acute Conditions Team, the Academic Research and Educational Organizationhttp://www.greatnetwork.org/int/ gathering experts operating in the management of acute clinical conditions in the field of Critical care,Emergency Medicine and Cardiology in 78 countries Worldwide. Official Academic International Cooperation: More than 300 Papers/books in the field of Cardiology,Intensive Care and Emergency Medicine . More than 400 presentations, invited lectures and chairs at major international Congresses in the fields of Hypertension, Cardiology, Critical Care Medicine ,Internal Medicine and Emergency Medicine. He has worldwide expertice in Biomarkers in Acute Diseases and Prevention in Aging.
9:00-9:15
The Pathogenesis of Vascular Barrier Dysfunction

Can Ince, PhD

Short Bibliography Professor dr. Can Ince is a physiologist whose interest lies in peri-operative medicine. He heads the Department of Translational Physiology at the Academic Medical Center (AMC) of the University of Amsterdam where research is directed at cardiovascular aspects of peri-operative medicine. He is part-time staff member (40%) of the Department of Intensive Care of the Erasmus Medical Center Rotterdam (head prof Diederik Gommers). Prior to his current position he was professor of Experimental Anesthesiology at the Dept of Anesthesiology at the AMC. Before going to the AMC he was associate professor at the University Hospital of Rotterdam at the Intensive Care Unit of the Dept of General Surgery (head prof. HA Bruining). Prior to that he had worked at the Dept. of Infectious Diseases (University Hospital Leiden) for some ten years on immunological research. He has a PhD in immunology/cell physiology from the University of Leiden. He has degrees in electrical and electronic engineering (BSc University of Birmingham (UK), MSc Technical University of Delft (Netherlands). Prof Ince is past-president of the Dutch Physiological Society, former chairman of the Scientific Committee of the Netherlands Society for Intensive Care Medicine and past-president of the International Society of Oxygen Transport to Tissue.
9:15-9:30
Vasoplegic Shock: Definitions and Pathophysiology

Lui Forni, MD

9:30-9:45
Hepatorenal Syndrome: Does it Exist?

Mitra Nadim, MD, FASN

Mitra Nadim is an Associate Professor of Clinical Medicine in the Division of Nephrology and Hypertension at the University of Southern California. She completed her medical school at UCLA, Internal Medicine Residencey at the Beth Israel Hospital in Boston and Nephrology Fellowship at Brigham and Women’s / Massachusetts General Hospital joint program. She is the the renal system chair for the Year 2 Medical School curriculum at Keck School of Medicine and the Director of USC’s Hypertension Center.
9:45-10:00
Metabolic Acidosis in the Critically Ill Patient

Ron Wald, MD

Ron Wald is a nephrologist at St. Michael's Hospital in Toronto and an Associate Professor of Medicine at the University of Toronto. His primary research interest is in critical care nephrology and he has been involved in several clinical trials in this area. He is currently co-leading an international randomized controlled trial on the timing of renal replacement therapy in acute kidney injury. Ron also has an interest in the care provided to patients who survive an episode of acute kidney injury and has conducted research using large administrative datasets to study this population. He is co-leading a clinical trial comparing post-discharge follow-up with a nephrologist vs usual care after an episode of severe acute kidney injury.
10:00-10:30
SPECIAL LECTURE
New Advances in the Treatment of Sepsis

John Louis Vincent, MD PhD

Professor Vincent is Professor of intensive care medicine at the University of Brussels (Université Libre de Bruxelles) and intensivist in the Department of Intensive Care at Erasme University Hospital in Brussels. He obtained his PhD degree at the University of Brussels in 1982. He is a Past-President of the World Federation of Societies of Intensive and Critical Care Medicine (WFSICCM), the European Society of Intensive Care Medicine (ESICM), the European Shock Society (ESS), the Belgian Society of Intensive Care Medicine (SIZ), and the International Sepsis Forum (ISF). He was a Council member of the Society of Critical Care Medicine (SCCM) from 2011-2013. He is member of the Belgian Royal Academy of Medicine. Dr. Vincent has signed more than 900 original articles, some 400 book chapters and review articles, 1000 original abstracts, and has edited 102 books. He is co-editor of the “Textbook of Critical Care†(Elsevier Saunders) and the “Encyclopedia of Intensive Care Medicine†(Springer). He is the editor-in-chief of Critical Care, Current Opinion in Critical Care, and ICU Management & Practice and member of the editorial boards of about 30 other journals, including Critical Care Medicine (senior editor), the American Journal of Respiratory and Critical Care Medicine (AJRCCM), PLoS Medicine, Lancet Infectious Diseases, Intensive Care Medicine, Shock, the Journal of Critical Care and Annals of Intensive Care. Dr Vincent has received several awards including the College Medalist Award of the American College of Chest Physicians, the Society Medal (lifetime award) of the European Society of Intensive Care Medicine,), the distinguished investigator Award and the Lifetime Achievement Award of the Society of Critical Care Medicine, and the prestigious Belgian scientific award of the FRS-FNRS (Prix Scientifique Joseph Maisin-Sciences biomédicales cliniques). His name appears more than 1000 times in Pubmed, and his work has been cited more than 140,000 times; his H-index is 156. In recognition for these achievements, he was awarded the title of Baron by King Albert II of Belgium in 2013.
10:30-11:00
Coffee Break and Faculty Picture
STANDARD WORKSHOPS
Open to all participants and applicable to physicians, nurses and allied personnel.
Workshop Codes: C= Core workshop, I = Intermediate, A = Advanced, N= Nurses, AP = of interest to nurses and allied personnel
Workshops presented in a series are marked with a "1" for a primary workshop discussion in this area and "2" for a more complex or advanced discussion in this area. Please note that the series workshops 1 and 2 can be either taken subsequently (following each other) or they can each be taken independently (e.g. workshop 1 can be taken without taking workshop 2 and vice versa).
FOCUSED SYMPOSIA
These focused symposia are offered in 3 categories (3 sessions in each category) on Wednesday and Thursday and run concurrrently with the Standard Workshops. Sessions can be taken as a group (3) or independently. Selections made during online registration process.
Standard Workshop Group 1
11:00-12:30
11:00-12:30
A01 Who Should Get a Kidney Biomarker Assessment? (C,N,AP)
Several biomarkers are now available to assess kidney function and damage. Which patients should get these assessments and how should these be applied will be discussed in this case based workshop.

Rajit Basu, MD MS FCCM

Dr. Basu is dedicated to improving the recognition, treatment, and outcomes of critically ill children suffering acute kidney injury. As Co-Director of the Center for Acute Care Nephrology at Cincinnati Children's Hospital, Dr. Basu oversees projects in the pediatric intensive care unit investigating AKI prediction by risk stratified optimization of biomarkers (renal angina), biomarker and fluid overload directed renal replacement therapy initiation, and use of the EMR to provide clinical decision support for management of AKI and fluid balance. Prior to arriving at Cincinnati Children's in 2009, Dr. Basu completed his Pediatric Critical Care fellowship and Pediatric residency at Northwestern University in Chicago. Originally from South Bend, Indiana, he is a graduate of Indiana University Medical School and the University of Notre Dame (undergraduate degree in Biochemistry).

Jay Koyner, MD

Dr. Koyner is an Associate Professor of Medicine in the Section of Nephrology at the University of Chicago. He completed his Internal Medicine and Nephrology training at the University of Chicago Medical Center where he currently serves as the medical director of the Inpatient Dialysis Unit and Director of ICU Nephrology. His critical care nephrology research interests have focused on the utilization of plasma and urine biomarkers to improve patient risk stratification and outcomes in the setting of AKI. In addition to biomarkers, other research interests include predictive analytics, AKI following cardiac surgery, CRRT and AKI therapeutics. He has published over 80 peer-reviewed articles and book chapters on AKI and the care of patients in with kidney injury in the ICU.

Alex Zarbock, MD

Dr. Zarbock is a Clinician Scientist and the Director and Chair of the Department of Anesthesiology and Critical Care Medicine, at the University of Münster, Germany. He acquired training at the University of Münster (Anesthesiology and Critical Care Medicine). Dr. Zarbock is supported by the German Research Foundation. His research interests span various aspects of Critical Care Medicine, but center in critical care nephrology (renal replacement therapy), sepsis and organ protection. Dr. Zarbock’s current projects include measures to avoid acute kidney injury after surgery and the timing of renal replacement therapy in critically ill patients with acute kidney injury. He is also author and co-author of over 140 scientific articles and book chapters.
11:00-12:30
B02 Optimizing the CRRT Circuit (Access, Anticoagulation and Assessments) (C,N,AP)
Keeping the CRRT circuit open and working efficaciously requires a consideration of several factors including the access, membrane and anticoagulation. This workshop will highlight the best practices for maintaining and monitoring the circuit.

David Askenazi, MD, MSPH

Dr. Askenazi is the Medical Director of the Pediatric and Infant Center for Acute Nephrology (PICAN), whose mission is to impove the outcomes of infants and children at risk for acute kidney disease by performing excellent comprehensive multi-disciplinary care, research and education. Dr. Askenazi's research interest include: a) the role that acute kidney injury (AKI) has on short and long-term outcomes in neonates and pediatric patients, b) testing therapies to improve the short and long-term outcomes of neonates and pediatric patients with AKI, and c) improving the definition of neonatal AKI using urinary and serum biomarkers of AKI.

Ian Baldwin, RN, PhD, FACCCN

Professor Ian Baldwin; Introduction Ian is from Melbourne, Australia, where he is an educator for post registration Intensive Care Nursing at the Austin hospital, and has an association with both RMIT and Deakin university as Adjunct Professor. Ian has undertaken many research activities in the field of renal support therapies and has presented on many occasions in Australia, Asia, the United States and Europe, and is a recipient of the Vicenza 'Award' from the IRRIV, Italy. Ian has completed a Masters and PhD in RRT clinical research, and is a past winner of �best nursing paper� at the Australian Intensive Care Society meeting in 1999 and "best nursing scholar" award in 2005. Ian has over 110 publications devoted to CRRT and other research activities in critical care and has authored multiple book chapters for hemofiltration. Ian is a reviewer for Australian Critical Care, the American Journal of Kidney Diseases,Intensive Care Medicine,and an Associate Editor for Blood Purification .

Ashita Tolwani, MD

Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
11:00-12:30
C03 Assessment of Fluid Responsiveness, Hemodynamic Monitoring and Targets (C,N)
Determining which patient needs fluids, what type and how much are key questions to be addressed in this workshop which will cover the principles and strategies for volume assessment, hemodynamic and microcirculatory monitoring in critically ill patients.

Can Ince, PhD

Short Bibliography Professor dr. Can Ince is a physiologist whose interest lies in peri-operative medicine. He heads the Department of Translational Physiology at the Academic Medical Center (AMC) of the University of Amsterdam where research is directed at cardiovascular aspects of peri-operative medicine. He is part-time staff member (40%) of the Department of Intensive Care of the Erasmus Medical Center Rotterdam (head prof Diederik Gommers). Prior to his current position he was professor of Experimental Anesthesiology at the Dept of Anesthesiology at the AMC. Before going to the AMC he was associate professor at the University Hospital of Rotterdam at the Intensive Care Unit of the Dept of General Surgery (head prof. HA Bruining). Prior to that he had worked at the Dept. of Infectious Diseases (University Hospital Leiden) for some ten years on immunological research. He has a PhD in immunology/cell physiology from the University of Leiden. He has degrees in electrical and electronic engineering (BSc University of Birmingham (UK), MSc Technical University of Delft (Netherlands). Prof Ince is past-president of the Dutch Physiological Society, former chairman of the Scientific Committee of the Netherlands Society for Intensive Care Medicine and past-president of the International Society of Oxygen Transport to Tissue.

David Selewski, MD

I am an Assistant Professor in the Department of Pediatrics within the Division of Nephrology at the University of Michigan. I received my training in pediatrics and pediatric nephrology at the University of Michigan. My clinical and research interests include pediatric critical care nephrology including pediatric & neonatal acute kidney injury, fluid overload, and continuous renal replacement therapy.

John Louis Vincent, MD PhD

Professor Vincent is Professor of intensive care medicine at the University of Brussels (Université Libre de Bruxelles) and intensivist in the Department of Intensive Care at Erasme University Hospital in Brussels. He obtained his PhD degree at the University of Brussels in 1982. He is a Past-President of the World Federation of Societies of Intensive and Critical Care Medicine (WFSICCM), the European Society of Intensive Care Medicine (ESICM), the European Shock Society (ESS), the Belgian Society of Intensive Care Medicine (SIZ), and the International Sepsis Forum (ISF). He was a Council member of the Society of Critical Care Medicine (SCCM) from 2011-2013. He is member of the Belgian Royal Academy of Medicine. Dr. Vincent has signed more than 900 original articles, some 400 book chapters and review articles, 1000 original abstracts, and has edited 102 books. He is co-editor of the “Textbook of Critical Care†(Elsevier Saunders) and the “Encyclopedia of Intensive Care Medicine†(Springer). He is the editor-in-chief of Critical Care, Current Opinion in Critical Care, and ICU Management & Practice and member of the editorial boards of about 30 other journals, including Critical Care Medicine (senior editor), the American Journal of Respiratory and Critical Care Medicine (AJRCCM), PLoS Medicine, Lancet Infectious Diseases, Intensive Care Medicine, Shock, the Journal of Critical Care and Annals of Intensive Care. Dr Vincent has received several awards including the College Medalist Award of the American College of Chest Physicians, the Society Medal (lifetime award) of the European Society of Intensive Care Medicine,), the distinguished investigator Award and the Lifetime Achievement Award of the Society of Critical Care Medicine, and the prestigious Belgian scientific award of the FRS-FNRS (Prix Scientifique Joseph Maisin-Sciences biomédicales cliniques). His name appears more than 1000 times in Pubmed, and his work has been cited more than 140,000 times; his H-index is 156. In recognition for these achievements, he was awarded the title of Baron by King Albert II of Belgium in 2013.
11:00-12:30
D04 Managing Patients with Combined Kidney and Liver Failure (C,N,AP)
Patients with combined liver and kidney failure are difficult to manage. This workshop will discuss the pathophysiology and illustrate best approaches for differential diagnosis and management of these patients.

Akash Deep, Dr

Dr Akash Deep is the Director of the Paediatric Intensive Care Unit(PICU) at King's College Hospital, London and Reader in Paediatric Intensive Care at King’s College London. Dr Deep is the Chair for the Critical Care Nephrology Section of European Society of Paediatric and Neonatal Intensive Care Society (ESPNIC). He has organised and taught on several national and international meetings. Dr Deep is the Chair for the Science and Education Committee of Paediatric Intensive Care Society (PICS) of UK. Dr Deep is the key medical advisor to the UK Sepsis Trust Executive Committee and the main author for the National Paediatric Sepsis Toolkits for Paediatrics. Dr Deep has co-authored the safety netting leaflet for sepsis awareness for parents in the UK. He is the spokesperson on sepsis for the Royal College of Paediatrics and Child Health and the All Party Parliamentary Group on sepsis. Dr Deep has organised many national and international congresses on CRRT and hosted the prestigious 8th International Conference on CRRT in London and the 9th International Conference on CRRT in Orlando, USA. He will be organising Chairman for 2019 U.K’s national Paediatric Intensive Care congress in collaboration with America’s Paediatric Cardiac Intensive Care Society (PCICS) He has authored several research articles in leading peer-reviewed journals and written chapters for leading publishers. He is the Chief Editor for the first ever book published by Springer on ‘’Critical Care Nephrology and Renal Replacement therapy in Children’’. He was awarded the National Bronze award in 2016-17 for his exemplary contribution to the NHS. Special interests include acute liver failure, acute kidney injury, CRRT, haemodynamics in septic shock, sepsis awareness campaigns and liver assist devices in liver failure.

Mitra Nadim, MD, FASN

Mitra Nadim is an Associate Professor of Clinical Medicine in the Division of Nephrology and Hypertension at the University of Southern California. She completed her medical school at UCLA, Internal Medicine Residencey at the Beth Israel Hospital in Boston and Nephrology Fellowship at Brigham and Women’s / Massachusetts General Hospital joint program. She is the the renal system chair for the Year 2 Medical School curriculum at Keck School of Medicine and the Director of USC’s Hypertension Center.
11:00-12:30
E05 Establishing and Maintaining Core Competencies for Nurses for CRRT (I,N,AP)
NURSES TRACK (E Series)
Competency based education and training are a key feature to establish an efficient CRRT program. This workshop will discuss the core curriculum for nursing education, training and skills assessment for performing CRRT and hybrid techniques.

Eileen Lischer, MA, BSN, RN, CNN

Eileen Lischer RN BSN MA has over 37 years of Nephrology nursing experience. She has worked as an educator and a nurse manager. Currently she is the Acute Dialysis Administrative Nurse for all four programs at the University of California Medical Center, San Diego. Her expertise includes adult and pediatric hemodialysis, CRRT, intra operative CRRT, peritoneal dialysis and apheresis. Eileen works collaboratively with the Critical Care Units to educate the primary care nurses in CRRT concepts and system applications. She coordinates a Diabetic Initiative focused on improving patient outcomes through nurse education. Eileen is actively involved in both kidney and liver research projects. She is a lecturer at the UCSD Extension program.

Theresa Mottes, MSN, RN,CPNP-AC,CDN

Theresa Mottes has over 20 years of pediatric renal replacement therapy experience is both the critical care setting and the outpatient dialysis setting. She has been involved in research with acute kidney injury, continuous renal replacement therapies and simulation based education for CRRT training. Theresa currently is a nurse practitioner for critical care nephrology. Theresa is very active with ANNA, as the current Pediatric Specialty Practice Network facilitator. She has presented at both national and international conferences.
11:00-12:30
F06 Principles, Applications and Practical Issues of Plasma Exchange (C,N,AP)
Plasma exchange (PE) is increasingly utilized in the ICU with CRRT and other extracorporeal techniques.

Isagani Marquez, MSN, RN, QIA

Eisei Noiri, MD., PhD. FASN.

Eisei NOIRI graduated from Hamamatsu University School of Medicine (HUSM) and received PhD at The University of Tokyo under Prof. Kiyoshi Kurokawa. He spent three years in SUNY Stony Brook and BNL under Prof. Michael Goligorsky. He is one of the chief researchers in Division of Nephrology and head of Department of Hemodialysis and Apheresis in The University of Tokyo Hospital. His research interests are broad from basic sciences in AKI pathophysiology, clinical applicability of biomarkers, epidemiology of CRRT, theoretical consideration to CRRT and apheresis therapy, and more.

Amber Sanchez, MD

Amber P. Sanchez received her M.D. with AOA distinction from the University of Texas Medical School at Houston. Her residency, chief residency, and fellowship were completed at the University of California San Diego (UCSD) where she has been on the faculty since 2010. Dr. Sanchez is board certified in Internal Medicine and Nephrology and has a special interest in therapeutic apheresis and glomerulonephritis. She has served as the Associate Medical Director for the UCSD Therapeutic Apheresis Program since 2010. She is the co-creator and course director for UCSD's Essentials and Advances in Apheresis Therapies conference that is held in San Diego annually.
12:30-2:00
Lunch Symposia Hosted by Conference (RSVP Required)
Selection made during registration
Lunch Symposia
12:30-2:00
12:30-2:00
Lunch Symposium W1
Citrate Anticoagulation for CRRT: Techniques and Results
CME Available
Regional citrate anticoagulation (RCA) is increasingly utilized for CRRT and many techniques are now used. Advances in technology have enabled automated citrate anticoagulation. However, concerns remain about its ease of use and application in patients with liver failure and reduced tissue perfusion. This symposium will discuss the best approaches for utilizing RCA for CRRT.
Moderators: Goldstein and Ward
The Why, How and What of Citrate Anticoagulation - Tolwani
Automated Citrate Delivery: Does it Work? - LeGrand
Metabolic Consequences of Citrate - Ostermann

Stuart Goldstein, MD

Dr. Goldstein serves as Director for the Center for Acute Care Nephrology (CACN) at Cincinnati Children's Hospital Medical Center. The CACN's mission is to coordinate all AKI related clinical, research and outcomes efforts at CCHMC and to function as a nexus for coordinating multi-center pediatric AKI research. Dr. Goldstein is the Founder and Principal Investigator of the Prospective Pediatric AKI Research Group (www.ppaki.org), a 50 center international pediatric acute care nephrology research consortium that will focuses on pediatric AKI epidemiology, interventional trials, device evaluation and genetic studies. Dr. Goldstein is also the program director for the only Pediatric Acute Care Nephrology fellowship in the United States.

Matthieu LeGrand, Pr

Pr Matthieu Legrand is Professor of Anesthesiology and Critical care medicine. He holds a PhD in physiology. He Works in the Department of anesthesiology, Critical care and burn unit of St-Louis hospital, university Paris Diderot, France. He has carried preclinical and clinical research in the field of critical care medicine with a special interest in critical care nephrology, sepsis and in burn critical care. He has served as a reviewer for several peer-review journals and expert in the field of critical care for several commitees and task forces.

Marlies Ostermann, MD

Dr Ostermann is a Consultant in Critical Care & Nephrology at Guy’s & St Thomas’ Foundation Trust, London and Honorary Senior Lecturer at King’s College London. After medical school in Goettingen (Germany), she did her postgraduate training in London and Canada. She holds a PhD degree from the University of Goettingen, an MD degree from the University of London and a postgraduate Diploma in Medical Education. She is an active member of the European Society of Intensive Care Society, Renal Association and Intensive Care Society UK, and a Fellow of the Faculty of Intensive Care Medicine. She is also a co-founder of the London AKI Network. Her research interests include acute kidney injury in critically ill and all aspects of renal replacement therapy.

Ashita Tolwani, MD

Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.

David Ward, MD, FRCP

David Ward trained as a nephrologist in his native Scotland and then did a second fellowship in renal immunopathology at Scripps Research in San Diego. He joined the Division of Nephrology at UCSD in 1977, and throughout has been one of its most active academic clinicians. He directed a laboratory research program in experimental glomerular pathology for several years, and for two decades was chief of clinical nephrology and director of dialysis. He founded UCSD’s therapeutic apheresis program in 1982 and was its director for 35 years. At different times he served as Assistant Dean of Clinical Affairs, Chief of Staff of the Hospital, and Chairman of the UCSD Medical Group. His other contributions include the invention of citrate-anticoagulated CRRT and innovations in hemodialysis technology and apheresis. He has published in all these areas and authored chapters in several standard textbooks. Since his semi-retirement in July 2017, he remains in part-time practice in apheresis and transplantation medicine, and consults on complex immunological and glomerular disease cases. He continues to teach on these topics and is a frequent invited speaker at national meetings.
12:30-2:00
Lunch Symposium W2
Phenotypes of Shock: Which Fluid, Which Vasopressor?
CME Available
There is increasing evidence that different patient respond differently to fluids and vasopressor management for shock. This symposium will discuss how best we may identify phenotypes to personalize fluid type (colloids and crystalloids and blood products) and volume and vasopressor management in shock patients to improve outcomes.
Moderators: Prowle and Vincent
Fluid Responsiveness Phenotypes: Lessons from ARDS Trials - Liu
Shock States Differ in Response to Vasopressors - Forni
Is the Microcirculation the Appropriate Target for Fluids and Vasopressors? - Ince

Lui Forni, MD

Can Ince, PhD

Short Bibliography Professor dr. Can Ince is a physiologist whose interest lies in peri-operative medicine. He heads the Department of Translational Physiology at the Academic Medical Center (AMC) of the University of Amsterdam where research is directed at cardiovascular aspects of peri-operative medicine. He is part-time staff member (40%) of the Department of Intensive Care of the Erasmus Medical Center Rotterdam (head prof Diederik Gommers). Prior to his current position he was professor of Experimental Anesthesiology at the Dept of Anesthesiology at the AMC. Before going to the AMC he was associate professor at the University Hospital of Rotterdam at the Intensive Care Unit of the Dept of General Surgery (head prof. HA Bruining). Prior to that he had worked at the Dept. of Infectious Diseases (University Hospital Leiden) for some ten years on immunological research. He has a PhD in immunology/cell physiology from the University of Leiden. He has degrees in electrical and electronic engineering (BSc University of Birmingham (UK), MSc Technical University of Delft (Netherlands). Prof Ince is past-president of the Dutch Physiological Society, former chairman of the Scientific Committee of the Netherlands Society for Intensive Care Medicine and past-president of the International Society of Oxygen Transport to Tissue.

Kathleen Liu, MD, PhD, MAS

Kathleen D. Liu, MD, PhD, MAS is a Professor in the Departments of Medicine and Anesthesia, Divisions of Nephrology and Critical Care Medicine at the University of California, San Francisco. Dr. Liu graduated from the University of California, San Francisco and trained as a resident at the Brigham and Womens Hospital in Boston. She trained in nephrology and critical care at the University of California, San Francisco. She is board-certified in both nephrology and critical care. Her research interests include biomarkers of kidney disease, acute kidney injury and acute lung injury.

John Prowle, MA MSc MD FRCP FFICM

Dr Prowle is a Senior Clinical Lecturer in Intensive Care Medicine within the Critical Care and Perioperative Medicine Research Group at Barts and the London School of Medicine and Dentistry, Queen Mary University of London and is an Honorary Consultant Physician in Intensive Care Medicine and Nephrology at the Royal London Hospital, Barts Health NHS Trust, London, UK. He graduated in medicine from the University of Cambridge in 1999 and undertook Doctoral Research under the supervision of Prof Rinaldo Bellomo in Melbourne, Australia leading to the award of his research doctorate in 2013. Dr Prowle’s academic interests include the Pathogenesis, Diagnosis and Treatment and Outcomes of Acute Kidney Injury, Continuous Renal Replacement Therapies in the ICU, Fluid Therapy and Medical Complications of Major Surgery. Since 2009 he has co-authored over 80 peer-reviewed publications and book chapters, including chapters related to Acute Kidney Injury in the latest editions of the Oxford Textbook of Clinical Nephrology and the Oxford Textbook of Critical Care.

John Louis Vincent, MD PhD

Professor Vincent is Professor of intensive care medicine at the University of Brussels (Université Libre de Bruxelles) and intensivist in the Department of Intensive Care at Erasme University Hospital in Brussels. He obtained his PhD degree at the University of Brussels in 1982. He is a Past-President of the World Federation of Societies of Intensive and Critical Care Medicine (WFSICCM), the European Society of Intensive Care Medicine (ESICM), the European Shock Society (ESS), the Belgian Society of Intensive Care Medicine (SIZ), and the International Sepsis Forum (ISF). He was a Council member of the Society of Critical Care Medicine (SCCM) from 2011-2013. He is member of the Belgian Royal Academy of Medicine. Dr. Vincent has signed more than 900 original articles, some 400 book chapters and review articles, 1000 original abstracts, and has edited 102 books. He is co-editor of the “Textbook of Critical Care†(Elsevier Saunders) and the “Encyclopedia of Intensive Care Medicine†(Springer). He is the editor-in-chief of Critical Care, Current Opinion in Critical Care, and ICU Management & Practice and member of the editorial boards of about 30 other journals, including Critical Care Medicine (senior editor), the American Journal of Respiratory and Critical Care Medicine (AJRCCM), PLoS Medicine, Lancet Infectious Diseases, Intensive Care Medicine, Shock, the Journal of Critical Care and Annals of Intensive Care. Dr Vincent has received several awards including the College Medalist Award of the American College of Chest Physicians, the Society Medal (lifetime award) of the European Society of Intensive Care Medicine,), the distinguished investigator Award and the Lifetime Achievement Award of the Society of Critical Care Medicine, and the prestigious Belgian scientific award of the FRS-FNRS (Prix Scientifique Joseph Maisin-Sciences biomédicales cliniques). His name appears more than 1000 times in Pubmed, and his work has been cited more than 140,000 times; his H-index is 156. In recognition for these achievements, he was awarded the title of Baron by King Albert II of Belgium in 2013.
12:30-2:00
Lunch Symposium W3
Extracorporeal Organ Support (ECOS) for Multi Organ Failure and Sepsis
CME Available
Membrane characteristics have evolved to enhance the removal of solutes of different sizes and configurations providing novel methods for blood purification. This symposium will cover the recent advances in this field and discuss how best to utilize these techniques.
Moderators: Honore and Deep
Advances in Membrane Technology - Ronco
Sorbent Based Toxin Removal - Kellum
Apheresis Techniques: Do They Have a Role? - Noiri

Akash Deep, Dr

Dr Akash Deep is the Director of the Paediatric Intensive Care Unit(PICU) at King's College Hospital, London and Reader in Paediatric Intensive Care at King’s College London. Dr Deep is the Chair for the Critical Care Nephrology Section of European Society of Paediatric and Neonatal Intensive Care Society (ESPNIC). He has organised and taught on several national and international meetings. Dr Deep is the Chair for the Science and Education Committee of Paediatric Intensive Care Society (PICS) of UK. Dr Deep is the key medical advisor to the UK Sepsis Trust Executive Committee and the main author for the National Paediatric Sepsis Toolkits for Paediatrics. Dr Deep has co-authored the safety netting leaflet for sepsis awareness for parents in the UK. He is the spokesperson on sepsis for the Royal College of Paediatrics and Child Health and the All Party Parliamentary Group on sepsis. Dr Deep has organised many national and international congresses on CRRT and hosted the prestigious 8th International Conference on CRRT in London and the 9th International Conference on CRRT in Orlando, USA. He will be organising Chairman for 2019 U.K’s national Paediatric Intensive Care congress in collaboration with America’s Paediatric Cardiac Intensive Care Society (PCICS) He has authored several research articles in leading peer-reviewed journals and written chapters for leading publishers. He is the Chief Editor for the first ever book published by Springer on ‘’Critical Care Nephrology and Renal Replacement therapy in Children’’. He was awarded the National Bronze award in 2016-17 for his exemplary contribution to the NHS. Special interests include acute liver failure, acute kidney injury, CRRT, haemodynamics in septic shock, sepsis awareness campaigns and liver assist devices in liver failure.

Patrick Honore, MD, PhD

Prof Patrick Honoré, MD,PhD,FCCM Intensivist-Nephrologist Co-Director of ICU Dept and Prof of Medicine Coordinator of Critical Care Research Department Centre Hospitalier Universitaire Brugmann/Brugmann University Hospital B-1020 Brussels (Laeken ) BELGIUM Patrick Honoré, graduated from Louvain Medical School as MD (1988), Specialist in Internal Medicine (1993), Intensive Care Specialist (1994) and Nephrologist (1995). During his internship, he completed more than 2 1/2 years specialisation in Nephrology and Dialysis. For almost 5 years, he received ICU training abroad (United Kingdom, Australia and USA). Pr Honoré is Board member of the Belgian Intensive Care Society and closely involved in the Nephrology section of the European Society of Intensive Care Medicine. He is also a distinguished member or consultant of many scientific committees and decision-making organizations dedicated to diagnosis, treatment, and research in the field of acute kidney injury in the critically ill. Pr Honoré authored or co-authored more than 228 peer-reviewed papers ,more than 600 abstracts and more than 75 book chapters . He was also editor of three books dedicated to Critical Care Nephrology.He has been invited as a speaker at more than 650 national and international conferences in almost 100 different countries. He acts as reviewer for more than 45 international journals, including top-ranking journals in the field of critical care medicine and nephrology. He is a member of the editorial board of several 25 high-standard journals. He is also Editor-In-Chief of the Journal of Translational Internal Medicine (open access) since 2013, editor-in-chief of Journal of Translational Critical Care Medicine & Journal of Translational Kidney Research since 2015 (open access too).He is also appointed as section editor for Renal in Annals of Intensive Care starting from February 2016.Since 2009, he fulltime fulfils the position of Head of Clinics in the Intensive Care department of the University Hospital, Vrije Universiteit Brussels (VUB) and became Clinical Tutor and Senior Lecturer at the VUB Faculty of Medicine.Since 2012, he fulfils the position of Full Professor at the VUB Faculty of Medicine. In the ICU department, he leads the Critical Care Nephrology Platform which incorporates intensivists, nephrologists and nurses dedicated to daily education, research and treatment of acute kidney injury. In particular, he directs and organizes continuous renal replacement therapy on a 24/24; 7/7 on-call basis.He has also start a CRRT program using citrate dedicated to small children (less than 10 kg) in the UZB -PICU since 2013.Since January 2018, he is holding the position of Co-Director of ICU Department , ICU Research Director, Prof of Medicine at CHU-Brugmann University Hospital

John Kellum, MD

John A. Kellum, MD, FACP, MCCM John A. Kellum, MD, MCCM is Professor of Critical Care Medicine, Medicine, Bioengineering and Clinical and Translational Science, and Vice Chair for Research within the Department of Critical Care Medicine and Director of the Center for Critical Care Nephrology at the University of Pittsburgh. Dr. Kellum received his medical degree from the Medical College of Ohio in 1984. His postgraduate training includes an internship and residency in Internal Medicine at the University of Rochester, NY, and a Fellowship in Critical Care Medicine at the University of Pittsburgh Medical Center. Dr. Kellum is actively involved in education, research and administration. Dr. Kellum’s research interests span various aspects of Critical Care Medicine, but center in critical care nephrology, sepsis and multi-organ failure, and clinical epidemiology, including consensus development and research methodology. He has authored more than 250 publications and has won several awards for teaching. He lectures widely and has given more than 300 seminars and invited lectures worldwide related to his research.

Eisei Noiri, MD., PhD. FASN.

Eisei NOIRI graduated from Hamamatsu University School of Medicine (HUSM) and received PhD at The University of Tokyo under Prof. Kiyoshi Kurokawa. He spent three years in SUNY Stony Brook and BNL under Prof. Michael Goligorsky. He is one of the chief researchers in Division of Nephrology and head of Department of Hemodialysis and Apheresis in The University of Tokyo Hospital. His research interests are broad from basic sciences in AKI pathophysiology, clinical applicability of biomarkers, epidemiology of CRRT, theoretical consideration to CRRT and apheresis therapy, and more.

Claudio Ronco, MD

Actual Position:
Dr. Claudio Ronco
Director
Department of Nephrology
St. Bortolo Hospital
Viale Rodolfi 16
I-36100 Vicenza
Italy

Name: Claudio Ronco

Date of birth: July 12, 1951

Education: High School Diploma at Vicenza Classic Lyceum “A.Pigafetta” in 1970 with the score: 45/60. Dr. Ronco Graduated in Medicine at University of Padua in 1976 with the score 110/110 and merit debating an experimental thesis on title “ Aspects of the Nitrogen metabolism in the nephrotic syndrome”.
From 1973 to 1976 has been intern at Institute of Clinical Internal Medicine I^ of the University of Padua, directed by Prof. E. Fiaschi, in the Nephrology Department II, under the supervision of the Prof. G. Maschio.

Postgraduate training: From July 1976 to November 1977 he has been internal resident at the Division of Internal Medicine of the St. Bortolo Hospital in Vicenza, directed by Prof. D. Corà.
In 1979 he has achieved the Specialization Diploma on Medical Nephrology at The postgraduate school of internal medicine of the University of Padua, with the score 70/70 debating a thesis on the “new methodologies for the measurement of the urinary bicarbonate”
In 1989 he has achieved the Diploma of Specialization in Pediatric Nephrology at University of Naples.
1982: Visiting Fellow at the Mount Sinai Hospital in New York, Department of Internal medicine, Nephrology Division, for four months. He carried out studies on hemofiltration and glomerular filtration with J.P. Bosh, S. Glabman and M. Levitt.
1984: Visiting Physician at the Mount Sinai Hospital In New York for two weeks and at VA Hospital in Los Angeles for two weeks.
1985: Visiting professor at the Nephrology Division of the George Washington University Hospital, Washington DC, and NIH at National Naval Medical Center of Bethesda for three months.
1988: Visiting professor at the Renal and Hypertension Division of George Washington University for three months.
1991: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
1995: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.

Teaching acitivity and Academic Qualifications: From 1978 to 1984 he has been in charge of the teaching program of Nephrology and Dialysis at Professional Nursing School in Vicenza.
During the academic years 1989-01 he has been in charge of teaching “Dialytic therapy” at Specialization School in Medical Nephrology of Padua University where he holds a post of Professor of Nephrology in charge of the teaching program concerning Hemodialysis and renal replacement therapies in critically ill patients.
October 1999-December 2000: Professor of Medicine at Albert Einstein College of Medicine and Director of the Renal laboratory at the Beth israel Medical Center in New York.
In the last ten years Professor Ronco was asked to deliver lectures and seminars in several Universities.
He has delivered in meetings and seminars more than 300 lectures and presentations.

In 1982 he introduced in Italy the use of continuous hemofiltration and in 1986 he published the first series of neonates treated with arteriovenous hemofiltration.
In 1985 He contributed to the introduction in Europe of high flux dialysis and derived therapies. He also established the dangerous effect of backfiltration in a contaminated dialysis fluid condition.
He has conducted a series of clinical and experimental researches in the following fields:
- Kinetics of fluid and solute removal in peritoneal dialysis and hemodialysis
- Treatment of Acute renal failure with intermittent and continuous therapies
- Renal replacement therapy in the neonate
- Development of new treatment modalities for acute and chronic renal failure.
- Studies on biomaterials
- Studies on glomerular filtration in humans and renal functional reserve
- Renal physiology in pregnancy
- Hydraulics and flow dynamics in the extracorporeal circulation
- Adequacy of dialysis
- Acid-Base Balance in uremia and dialysis
- Acute renal failure and Critical Care Nephrology

Professional employement and Hospital appointments:
Assistant of clinical nephrology from 1977 to 1984 at Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Associate of clinical nephrology from 1984 at Department of Nephrology , St. Bortolo Hospital, Vicenza, Italy.
From 1984 he is director of the hemodialysis and peritoneal dialysis center of the Department of Nephrology at St. Bortolo Hospital, Vicenza, Italy.
From October 25, 1999 to December 1st 2000 Dr. Ronco has been Director of the research laboratory of Hemodialysis at the Beth Israel Medical center of New York and Visiting Professor of Medicine at the Albert Einstein College of Medicine of new York
Today Dr. Ronco is director of the Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.

Board certification: In 1989 he has achieved in Rome, the National License for Nephrology Chair and Directional Functions, with the score 94/100.

Professional Society Membership: He is mamber of the council of several scientific societies and he is editor in chief of the international journal of artificial organs and contributions to nephrology.

Awards and honors:
1983 Schwartz Award, for the best paper of the year at St. Bortolo Hospital.
1984 G.F. Volpato Grant for the best research project on acute renal failure in Italy
1989 Best paper Prize at the Italian Society of nephrology meeting.
1991 ESAO RESEARCH AWARD for the best paper presented at the European Society for Artificial Organs.
1996 Arturo Borsatti Award of Padova University as a best nephrologist of the year.
2004 Lifetime achievement award

Other professional activities: He has organized several congresses and meetings in the area of nephrology and Intensive care from 1982 to today.
He is member of several advisory groups for clinical trials and dialysis research.

Lectures and publications: Dr. Ronco has coauthored 560 papers, 36 book chapters, 26 books, 7 monographic journal issues and has delivered more than 300 lectures in international meetings and universities. His personal impact factor calculated at december 2002 is 391.
12:30-2:00
Lunch Symposium W4
Quality Metrics in AKI and CRRT: Establishing Benchmarks
CME Available
AKI is a complex disease that requires multidisciplinary interventions however there are currently limited measures to assess quality of care for AKI management. This symposium will discuss the recommendations from the ADQI 22 meeting and highlight some of the practical issues for implementing a quality program for AKI and CRRT
Moderators: Cerda and Selby
Quality of Care in AKI: What are the Consensus Recommendation from ADQI? - Kashani
Implementing a Quality Program for AKI in your ICU: Lessons from Pediatrics - Mottes
What Benchmarks Should We Use for Measuring Quality in CRRT? - Bagshaw

Sean Bagshaw, MD, MSc, FRCPC

Dr. Bagshaw is a Clinician Scientist and Assistant Professor in the Division of Critical Care Medicine, at the University of Alberta in Edmonton, Alberta, Canada. He acquired training at the University of Calgary (Internal Medicine, Critical Care Medicine, Masters of Science Epidemiology) prior to completing a critical care nephrology fellowship in the Department of Intensive Care Medicine, at the Austin Hospital in Melbourne, Australia. Dr. Bagshaw is supported by a Canada Research Chair in Critical Care Nephrology and a Clinical Investigator Award from Alberta Innovates - Health Solutions. Dr. Bagshaw's main research interests have focused on the clinical, epidemiological and translational issues related to acute kidney injury and the application of extracorporeal blood purification in critically ill patients. Dr. Bagshaw's current projects include diuretic therapy in early acute kidney injury and factors related with the initiation of renal support in critically ill patients. He has published over 100 peer-reviewed papers, numerous book chapters, and peer-reviewed for over 20 medical journals. Dr. Bagshaw is a member of several organizations including the Canadian Critical Care Society, Canadian Critical Care Trials Group, Australia New Zealand Intensive Care Society, and the Acute Kidney Injury Network, and the Acute Dialysis Quality Initiative.

Jorge Cerda, MD, MS, FACP, FASN

Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY Clinical Associate Professor of Medicine, Albany Medical College, Albany NY Fulbright Scholar, 1980 Fellow, American College of Physicians Fellow, American Society of Nephrology Organizing Committee, International Conference AKI & CRRT AKI Advisory Group, American Society of Nephrology AKI Committee, and "0by25" Initiative, International Society of Nephrology Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease Associate Editor, Blood Purification and Kidney International Reports Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world

Kianoush Kashani, MD

Kianoush Kashani, MD is a consultant in the Division of Nephrology and Hypertension, Division of Pulmonary and Critical Care at Mayo Clinic, Rochester. His academic rank is Professor in Internal Medicine and Assistant Professor in Medical Education. His research interest is acute kidney injury, electrolyte disorders, simulation medicine, and critical care point-of-care ultrasonography.

Theresa Mottes, MSN, RN,CPNP-AC,CDN

Theresa Mottes has over 20 years of pediatric renal replacement therapy experience is both the critical care setting and the outpatient dialysis setting. She has been involved in research with acute kidney injury, continuous renal replacement therapies and simulation based education for CRRT training. Theresa currently is a nurse practitioner for critical care nephrology. Theresa is very active with ANNA, as the current Pediatric Specialty Practice Network facilitator. She has presented at both national and international conferences.

Nick Selby, MD

Dr Selby studied medicine at the University of Nottingham, graduating in 1998, and after completing post-graduate training in the East Midlands was appointed a full-time NHS consultant nephrologist at the Royal Derby Hospital in 2009. In 2015 he was appointed Associate Professor of Nephrology at the University of Nottingham, based in the Centre for Kidney Research and Innovation (www.nottingham.ac.uk/research/groups/renal), Royal Derby Hospital Postgraduate Medical School. Dr. Selby is a clinical academic with primary interests in Acute Kidney Injury (AKI), Magnetic Resonance Imaging (MRI) of the kidney and the haemodynamic consequences of dialysis. He led the development of one of the first e-alert systems for AKI in the UK and is CI on several investigator-instigated studies in these areas. Since 2011 Dr Selby has been awarded peer reviewed grant funding from MRC, the Health Foundation, Kidney Research UK and British Renal Society. He has published over 60 peer-reviewed articles. Dr Selby has several national AKI roles, including leadership of the AKI Clinical Study Group that sits within the UK Kidney Research Consortium, the co-chair of the UK Renal Imaging Network and programme board of the NHS England ‘Think Kidneys’ programme.
12:30-2:00
Lunch Symposium I1
Additional Industry Session Offered (Non-CME)
TBA

Wednesday, Afternoon, February 27

Standard Workshop Group 2
2:00-3:30
2:00-3:30
A07 Can Kidney Biomarkers Help Timely Interventions and Prognostication? (C,N,AP)
Clinicians need to determine when a specific intervention is needed and what is the likelihood of modifying the disease course. This workshop will discuss how novel renal biomarkers can be leveraged to guide specific interventions in patients with AKI in different settings.

Salvatore diSomma, Professor of Medicin

Name: Salvatore Surname: Di Somma Place and date of birth: Naples (Italy), 7.6.1953. Graduate in Medicine “cum laude†(University of Naples), 1978. Post Graduate “cum Laude†in Internal Medicine (University of Naples), 1983. Post Graduate “cum Laude†in Cardiology (University of Naples), 1987. Current Position Professor of Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome, Department of Medical-Surgery Sciences and Translational Medicine since 2002. Chairman Postgraduate School of Emergency Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome, since 2002. Professor Postgraduate Schools of Internal Medicine and Cardiovascular Diseases Academic Positions Research Fellow - Department of Clinical and Experimental Medicine ’University “Federico II†of Naples from 1978 to 2001. Assistant Professor – Emergency Medicine and Cardioangiology – University Federico II of Naples, from 1978 al 2001. Research Fellow in Cardiology University of Pavia, 1989-1992. Assistant Professor Department of Medicine New York Medical College New York U.S.A. 1994-1996 Cardiovascular Research Institute. Minisrty of Health World Class Professor Programme , Brawijaya University Malang(Indonesia) Expert Professor in Medicinea and Cardiovascular Prevention;University of Lund (Malmoe (Sweden) Visiting Professor-Scholar Researcher -UCSD University California San Diego(USA) Scientific Societies Membership President of GREAT Network Italy President Scientific Committee of AISC (Italian Association of Patients with Heart Failure) Former President of GREAT Global Research on Acute Conditions Team, the Academic Research and Educational Organizationhttp://www.greatnetwork.org/int/ gathering experts operating in the management of acute clinical conditions in the field of Critical care,Emergency Medicine and Cardiology in 78 countries Worldwide. Official Academic International Cooperation: More than 300 Papers/books in the field of Cardiology,Intensive Care and Emergency Medicine . More than 400 presentations, invited lectures and chairs at major international Congresses in the fields of Hypertension, Cardiology, Critical Care Medicine ,Internal Medicine and Emergency Medicine. He has worldwide expertice in Biomarkers in Acute Diseases and Prevention in Aging.

Jay Koyner, MD

Dr. Koyner is an Associate Professor of Medicine in the Section of Nephrology at the University of Chicago. He completed his Internal Medicine and Nephrology training at the University of Chicago Medical Center where he currently serves as the medical director of the Inpatient Dialysis Unit and Director of ICU Nephrology. His critical care nephrology research interests have focused on the utilization of plasma and urine biomarkers to improve patient risk stratification and outcomes in the setting of AKI. In addition to biomarkers, other research interests include predictive analytics, AKI following cardiac surgery, CRRT and AKI therapeutics. He has published over 80 peer-reviewed articles and book chapters on AKI and the care of patients in with kidney injury in the ICU.

Patrick Murray, Prof

Patrick Murray is Professor of Clinical Pharmacology in University College Dublin, and a consultant physician (clinical pharmacologist & nephrologist) at the Mater Misericordiae University Hospital, Dublin, Ireland. He received his medical education at University College Dublin, Ireland. Following his internship at the Mater Misericordiae University Hospital in Dublin, he completed a residency in internal medicine at Hennepin County Medical Center in Minneapolis, Minnesota, USA. He completed fellowship training programs in nephrology, critical care medicine, and clinical pharmacology at the University Of Chicago Hospitals in Chicago, Illinois, USA. He is board-certified in nephrology, critical care medicine, and clinical pharmacology. He practiced as an intensivist, nephrologist, and clinical pharmacologist at the University of Chicago Hospitals from 1996–2008, serving as the fellowship training program director in nephrology, also directing the Acute Dialysis Service. He has a longstanding interest in research and education to improve the prevention, diagnosis, and therapy of acute kidney injury and nephrotoxicity, and the pharmacotherapy of patients with kidney disease. He is a member of several international consensus groups that have produced guidelines for research and practice in the field of acute kidney injury (ADQI, AKIN, KDOQI). Since 2008, he has been the Professor of Clinical Pharmacology at University College Dublin, and a Consultant in Nephrology & Clinical Pharmacology at the Mater Misericordiae University Hospital. He is Chair of the Mater Misericordiae University Hospital Drugs & Therapeutics Committee. He is the Clinical Director of the UCD-Mater Clinical Research Centre. In 2011, he was appointed Associate Dean for International Affairs in the UCD School of Medicine and Medical Science. In 2012, he was appointed Director of the Dublin Centre for Clinical Research (DCCR) Consortium Network, and also Clinical Director of the Irish Clinical Research Infrastructure Network (ICRIN). Since December 2012, he has been the Dean and Head of the School of Medicine at UCD.
2:00-3:30
B08 Can We Achieve Precision Solute Control with CRRT? (I,N,AP)
CRRT techniques have evolved with availability of new technology to customize dialysis delivery. This interactive case based workshop will discuss how to apply the technology for dose adjustments, monitoring for adequacy, modality selection and transitions in CRRT.

Rolando Claure-Del Granado, MD, FASN

Rolando Claure-Del Granado received his medical degree from Universidad del Valle, School of Medicine, Cochabamba-Bolivia in 1999. His postgraduate training included a residency in Internal Medicine and a Fellowship in Nephrology at the Instituto Nacional de Ciencias Medicas y Nutricion "Salvador Zubiran" (U.N.A.M), Mexico city, Mexico. He was a Research Fellow at the Medicine Department - Division of Nephrology of the University of California San Diego, from 2009 to 2011. Following his fellowship he joined the faculty of Universidad Mayor de San Simon, School of Medicine in Cochabamba - Bolivia as a Professor of Medicine. He is a Clinical Research Investigator at the Biomedical Research Institute (IIBISMED) of the Universidad Mayor de San Simon School of Medicine in Cochabamba - Bolivia. He also is the Head of the Division of Nephrology, Dialysis and Transplantation of Hospital Obrero #2 - C.N.S. in Cochabamba - Bolivia. He is a member of the Acute Kidney Injury Committee of the Latin-American Society of Nephrology and Hypertension. He is the Chair of the Young Nephrologist Committee of the International Society of Nephrology (ISN-YNC) and member of the ISN Latin American Regional Board. He is an active member of the ISN Social Media Task Force. Dr. Claure-Del Granado's research interests include extracorporeal therapies for AKI, the assessment of acid-base metabolic disorders, biomarkers in AKI, and the use of social medial in education.

Claudio Ronco, MD

Actual Position:
Dr. Claudio Ronco
Director
Department of Nephrology
St. Bortolo Hospital
Viale Rodolfi 16
I-36100 Vicenza
Italy

Name: Claudio Ronco

Date of birth: July 12, 1951

Education: High School Diploma at Vicenza Classic Lyceum “A.Pigafetta” in 1970 with the score: 45/60. Dr. Ronco Graduated in Medicine at University of Padua in 1976 with the score 110/110 and merit debating an experimental thesis on title “ Aspects of the Nitrogen metabolism in the nephrotic syndrome”.
From 1973 to 1976 has been intern at Institute of Clinical Internal Medicine I^ of the University of Padua, directed by Prof. E. Fiaschi, in the Nephrology Department II, under the supervision of the Prof. G. Maschio.

Postgraduate training: From July 1976 to November 1977 he has been internal resident at the Division of Internal Medicine of the St. Bortolo Hospital in Vicenza, directed by Prof. D. Corà.
In 1979 he has achieved the Specialization Diploma on Medical Nephrology at The postgraduate school of internal medicine of the University of Padua, with the score 70/70 debating a thesis on the “new methodologies for the measurement of the urinary bicarbonate”
In 1989 he has achieved the Diploma of Specialization in Pediatric Nephrology at University of Naples.
1982: Visiting Fellow at the Mount Sinai Hospital in New York, Department of Internal medicine, Nephrology Division, for four months. He carried out studies on hemofiltration and glomerular filtration with J.P. Bosh, S. Glabman and M. Levitt.
1984: Visiting Physician at the Mount Sinai Hospital In New York for two weeks and at VA Hospital in Los Angeles for two weeks.
1985: Visiting professor at the Nephrology Division of the George Washington University Hospital, Washington DC, and NIH at National Naval Medical Center of Bethesda for three months.
1988: Visiting professor at the Renal and Hypertension Division of George Washington University for three months.
1991: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
1995: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.

Teaching acitivity and Academic Qualifications: From 1978 to 1984 he has been in charge of the teaching program of Nephrology and Dialysis at Professional Nursing School in Vicenza.
During the academic years 1989-01 he has been in charge of teaching “Dialytic therapy” at Specialization School in Medical Nephrology of Padua University where he holds a post of Professor of Nephrology in charge of the teaching program concerning Hemodialysis and renal replacement therapies in critically ill patients.
October 1999-December 2000: Professor of Medicine at Albert Einstein College of Medicine and Director of the Renal laboratory at the Beth israel Medical Center in New York.
In the last ten years Professor Ronco was asked to deliver lectures and seminars in several Universities.
He has delivered in meetings and seminars more than 300 lectures and presentations.

In 1982 he introduced in Italy the use of continuous hemofiltration and in 1986 he published the first series of neonates treated with arteriovenous hemofiltration.
In 1985 He contributed to the introduction in Europe of high flux dialysis and derived therapies. He also established the dangerous effect of backfiltration in a contaminated dialysis fluid condition.
He has conducted a series of clinical and experimental researches in the following fields:
- Kinetics of fluid and solute removal in peritoneal dialysis and hemodialysis
- Treatment of Acute renal failure with intermittent and continuous therapies
- Renal replacement therapy in the neonate
- Development of new treatment modalities for acute and chronic renal failure.
- Studies on biomaterials
- Studies on glomerular filtration in humans and renal functional reserve
- Renal physiology in pregnancy
- Hydraulics and flow dynamics in the extracorporeal circulation
- Adequacy of dialysis
- Acid-Base Balance in uremia and dialysis
- Acute renal failure and Critical Care Nephrology

Professional employement and Hospital appointments:
Assistant of clinical nephrology from 1977 to 1984 at Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Associate of clinical nephrology from 1984 at Department of Nephrology , St. Bortolo Hospital, Vicenza, Italy.
From 1984 he is director of the hemodialysis and peritoneal dialysis center of the Department of Nephrology at St. Bortolo Hospital, Vicenza, Italy.
From October 25, 1999 to December 1st 2000 Dr. Ronco has been Director of the research laboratory of Hemodialysis at the Beth Israel Medical center of New York and Visiting Professor of Medicine at the Albert Einstein College of Medicine of new York
Today Dr. Ronco is director of the Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.

Board certification: In 1989 he has achieved in Rome, the National License for Nephrology Chair and Directional Functions, with the score 94/100.

Professional Society Membership: He is mamber of the council of several scientific societies and he is editor in chief of the international journal of artificial organs and contributions to nephrology.

Awards and honors:
1983 Schwartz Award, for the best paper of the year at St. Bortolo Hospital.
1984 G.F. Volpato Grant for the best research project on acute renal failure in Italy
1989 Best paper Prize at the Italian Society of nephrology meeting.
1991 ESAO RESEARCH AWARD for the best paper presented at the European Society for Artificial Organs.
1996 Arturo Borsatti Award of Padova University as a best nephrologist of the year.
2004 Lifetime achievement award

Other professional activities: He has organized several congresses and meetings in the area of nephrology and Intensive care from 1982 to today.
He is member of several advisory groups for clinical trials and dialysis research.

Lectures and publications: Dr. Ronco has coauthored 560 papers, 36 book chapters, 26 books, 7 monographic journal issues and has delivered more than 300 lectures in international meetings and universities. His personal impact factor calculated at december 2002 is 391.

David Selewski, MD

I am an Assistant Professor in the Department of Pediatrics within the Division of Nephrology at the University of Michigan. I received my training in pediatrics and pediatric nephrology at the University of Michigan. My clinical and research interests include pediatric critical care nephrology including pediatric & neonatal acute kidney injury, fluid overload, and continuous renal replacement therapy.
2:00-3:30
C09 Starting, Transitioning and Stopping RRT for AKI: Science and Art (A)
One of the most vexing issues for clinicians is determining when to initiate RRT in critically ill patients, when and how to transition modalities and when it can be stopped. This workshop will use case studies to explore various approaches and establish the principles for clinical decisions for renal support.

Etienne Macedo, MD, PhD, FASN

Etienne Macedo graduated from the University of Sao Paulo (USP) in Sao Paulo, Brazil. She completed her residency and fellowship through the USP Hospital das Clinicas, and her post-doctorate at the University of California, San Diego, where she continues to work as a clinician and researcher in AKI.

Ravindra Mehta, MBBS, MD, DM, FACP

Dr. Mehta is Professor of Medicine in the Division of Nephrology and Associate Chair for Clinical Affairs in the Department of Medicine at the University of California, San Diego (UCSD) where he directs the Clinical nephrology and dialysis programs. He is also the Chair of the International Society of Nephrology Commission on Acute Renal Failure, founding member of the Acute Dialysis Quality Initiative. He received the M.B.B.S. degree (1976) from the Government Medical School in Amritsar, India, and the M.D. (1979) and D.M. (1981) degrees from the Post Graduate Institute of Medical Education and Research in Chandigarh, India. He subsequently completed a nephrology fellowship at the University of Rochester in Rochester New York and obtained his boards in internal medicine (1986) and Nephrology (1988). He has been on the faculty at San Diego since 1988. His reserach interests are in the field of acute renal failure and he has directed several clinical studies in the management of patients with ARF including comparing different dialytic modalities, conducting large multicenter observational studies of ARF with the PICARD group, evaluating different predictive models for outcomes in ARF, investigating the role of cytokine removal by dialysis membranes in sepsis and ARF, and evaluating techniques for determining the amount of excess fluid in dialysis patients.
2:00-3:30
D10 Managing Patients with Sepsis: Can We Modify the Course with Extracorporeal Organ Support (ECOS) (C,N,AP)
Septic patients often require ECOS to allow time for recovery. This workshop covers the rationale and strategies for the practical application of extracorporeal support techniques for sepsis. Case studies will be utilized to delineate different options.

Rajit Basu, MD MS FCCM

Dr. Basu is dedicated to improving the recognition, treatment, and outcomes of critically ill children suffering acute kidney injury. As Co-Director of the Center for Acute Care Nephrology at Cincinnati Children's Hospital, Dr. Basu oversees projects in the pediatric intensive care unit investigating AKI prediction by risk stratified optimization of biomarkers (renal angina), biomarker and fluid overload directed renal replacement therapy initiation, and use of the EMR to provide clinical decision support for management of AKI and fluid balance. Prior to arriving at Cincinnati Children's in 2009, Dr. Basu completed his Pediatric Critical Care fellowship and Pediatric residency at Northwestern University in Chicago. Originally from South Bend, Indiana, he is a graduate of Indiana University Medical School and the University of Notre Dame (undergraduate degree in Biochemistry).

Patrick Honore, MD, PhD

Prof Patrick Honoré, MD,PhD,FCCM Intensivist-Nephrologist Co-Director of ICU Dept and Prof of Medicine Coordinator of Critical Care Research Department Centre Hospitalier Universitaire Brugmann/Brugmann University Hospital B-1020 Brussels (Laeken ) BELGIUM Patrick Honoré, graduated from Louvain Medical School as MD (1988), Specialist in Internal Medicine (1993), Intensive Care Specialist (1994) and Nephrologist (1995). During his internship, he completed more than 2 1/2 years specialisation in Nephrology and Dialysis. For almost 5 years, he received ICU training abroad (United Kingdom, Australia and USA). Pr Honoré is Board member of the Belgian Intensive Care Society and closely involved in the Nephrology section of the European Society of Intensive Care Medicine. He is also a distinguished member or consultant of many scientific committees and decision-making organizations dedicated to diagnosis, treatment, and research in the field of acute kidney injury in the critically ill. Pr Honoré authored or co-authored more than 228 peer-reviewed papers ,more than 600 abstracts and more than 75 book chapters . He was also editor of three books dedicated to Critical Care Nephrology.He has been invited as a speaker at more than 650 national and international conferences in almost 100 different countries. He acts as reviewer for more than 45 international journals, including top-ranking journals in the field of critical care medicine and nephrology. He is a member of the editorial board of several 25 high-standard journals. He is also Editor-In-Chief of the Journal of Translational Internal Medicine (open access) since 2013, editor-in-chief of Journal of Translational Critical Care Medicine & Journal of Translational Kidney Research since 2015 (open access too).He is also appointed as section editor for Renal in Annals of Intensive Care starting from February 2016.Since 2009, he fulltime fulfils the position of Head of Clinics in the Intensive Care department of the University Hospital, Vrije Universiteit Brussels (VUB) and became Clinical Tutor and Senior Lecturer at the VUB Faculty of Medicine.Since 2012, he fulfils the position of Full Professor at the VUB Faculty of Medicine. In the ICU department, he leads the Critical Care Nephrology Platform which incorporates intensivists, nephrologists and nurses dedicated to daily education, research and treatment of acute kidney injury. In particular, he directs and organizes continuous renal replacement therapy on a 24/24; 7/7 on-call basis.He has also start a CRRT program using citrate dedicated to small children (less than 10 kg) in the UZB -PICU since 2013.Since January 2018, he is holding the position of Co-Director of ICU Department , ICU Research Director, Prof of Medicine at CHU-Brugmann University Hospital

Matthieu LeGrand, Pr

Pr Matthieu Legrand is Professor of Anesthesiology and Critical care medicine. He holds a PhD in physiology. He Works in the Department of anesthesiology, Critical care and burn unit of St-Louis hospital, university Paris Diderot, France. He has carried preclinical and clinical research in the field of critical care medicine with a special interest in critical care nephrology, sepsis and in burn critical care. He has served as a reviewer for several peer-review journals and expert in the field of critical care for several commitees and task forces.
2:00-3:30
E11 Infection Control for Extracorporeal Organ Support (ECOS) Techniques (I,N,AP)
NURSES TRACK (E Series)
Infection Control for Extracorporeal Organ Support (ECOS) TechniquesPatients undergoing ECOS are at a high risk for infections and require a concerted effort for surveillance, primary prevention and early interventions. This case based workshop will discuss the current guidelines for infection control for patients on ECOS.

Saima Aslam, MD

Dr Aslam is an Assistant Professor at the Division of Infectious Diseases at the University of California, San Diego (UCSD) and the Director of the Solid Organ Transplant Infectious Diseases service at the UCSD Medical Center. She obtained her medical degree with honors from the Aga Khan University in Karachi, Pakistan and subsequently completed Internal Medicine residency and Infectious Diseases fellowship from Baylor College of Medicine, Houston, TX. She received a Masters of Science in Clinical Investigation from the Graduate School of Biomedical Sciences, Baylor College of Medicine, Houston, TX. Dr Aslam's current NIH-funded research is in the area of hemodialysis catheter-related infections with a focus on biofilms.

Eileen Lischer, MA, BSN, RN, CNN

Eileen Lischer RN BSN MA has over 37 years of Nephrology nursing experience. She has worked as an educator and a nurse manager. Currently she is the Acute Dialysis Administrative Nurse for all four programs at the University of California Medical Center, San Diego. Her expertise includes adult and pediatric hemodialysis, CRRT, intra operative CRRT, peritoneal dialysis and apheresis. Eileen works collaboratively with the Critical Care Units to educate the primary care nurses in CRRT concepts and system applications. She coordinates a Diabetic Initiative focused on improving patient outcomes through nurse education. Eileen is actively involved in both kidney and liver research projects. She is a lecturer at the UCSD Extension program.

Theresa Mottes, MSN, RN,CPNP-AC,CDN

Theresa Mottes has over 20 years of pediatric renal replacement therapy experience is both the critical care setting and the outpatient dialysis setting. She has been involved in research with acute kidney injury, continuous renal replacement therapies and simulation based education for CRRT training. Theresa currently is a nurse practitioner for critical care nephrology. Theresa is very active with ANNA, as the current Pediatric Specialty Practice Network facilitator. She has presented at both national and international conferences.
2:00-3:30
F12 Pediatric and Adult AKI and CRRT: Collaborations Across the Age Spectrum (I,N,AP)
Although pediatric and adult patients have similar indications for CRRT the therapy application varies considerably. This workshop will highlight the best practices for CRRT application across the age spectrum.

David Askenazi, MD, MSPH

Dr. Askenazi is the Medical Director of the Pediatric and Infant Center for Acute Nephrology (PICAN), whose mission is to impove the outcomes of infants and children at risk for acute kidney disease by performing excellent comprehensive multi-disciplinary care, research and education. Dr. Askenazi's research interest include: a) the role that acute kidney injury (AKI) has on short and long-term outcomes in neonates and pediatric patients, b) testing therapies to improve the short and long-term outcomes of neonates and pediatric patients with AKI, and c) improving the definition of neonatal AKI using urinary and serum biomarkers of AKI.

Stuart Goldstein, MD

Dr. Goldstein serves as Director for the Center for Acute Care Nephrology (CACN) at Cincinnati Children's Hospital Medical Center. The CACN's mission is to coordinate all AKI related clinical, research and outcomes efforts at CCHMC and to function as a nexus for coordinating multi-center pediatric AKI research. Dr. Goldstein is the Founder and Principal Investigator of the Prospective Pediatric AKI Research Group (www.ppaki.org), a 50 center international pediatric acute care nephrology research consortium that will focuses on pediatric AKI epidemiology, interventional trials, device evaluation and genetic studies. Dr. Goldstein is also the program director for the only Pediatric Acute Care Nephrology fellowship in the United States.

Claudio Ronco, MD

Actual Position:
Dr. Claudio Ronco
Director
Department of Nephrology
St. Bortolo Hospital
Viale Rodolfi 16
I-36100 Vicenza
Italy

Name: Claudio Ronco

Date of birth: July 12, 1951

Education: High School Diploma at Vicenza Classic Lyceum “A.Pigafetta” in 1970 with the score: 45/60. Dr. Ronco Graduated in Medicine at University of Padua in 1976 with the score 110/110 and merit debating an experimental thesis on title “ Aspects of the Nitrogen metabolism in the nephrotic syndrome”.
From 1973 to 1976 has been intern at Institute of Clinical Internal Medicine I^ of the University of Padua, directed by Prof. E. Fiaschi, in the Nephrology Department II, under the supervision of the Prof. G. Maschio.

Postgraduate training: From July 1976 to November 1977 he has been internal resident at the Division of Internal Medicine of the St. Bortolo Hospital in Vicenza, directed by Prof. D. Corà.
In 1979 he has achieved the Specialization Diploma on Medical Nephrology at The postgraduate school of internal medicine of the University of Padua, with the score 70/70 debating a thesis on the “new methodologies for the measurement of the urinary bicarbonate”
In 1989 he has achieved the Diploma of Specialization in Pediatric Nephrology at University of Naples.
1982: Visiting Fellow at the Mount Sinai Hospital in New York, Department of Internal medicine, Nephrology Division, for four months. He carried out studies on hemofiltration and glomerular filtration with J.P. Bosh, S. Glabman and M. Levitt.
1984: Visiting Physician at the Mount Sinai Hospital In New York for two weeks and at VA Hospital in Los Angeles for two weeks.
1985: Visiting professor at the Nephrology Division of the George Washington University Hospital, Washington DC, and NIH at National Naval Medical Center of Bethesda for three months.
1988: Visiting professor at the Renal and Hypertension Division of George Washington University for three months.
1991: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
1995: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.

Teaching acitivity and Academic Qualifications: From 1978 to 1984 he has been in charge of the teaching program of Nephrology and Dialysis at Professional Nursing School in Vicenza.
During the academic years 1989-01 he has been in charge of teaching “Dialytic therapy” at Specialization School in Medical Nephrology of Padua University where he holds a post of Professor of Nephrology in charge of the teaching program concerning Hemodialysis and renal replacement therapies in critically ill patients.
October 1999-December 2000: Professor of Medicine at Albert Einstein College of Medicine and Director of the Renal laboratory at the Beth israel Medical Center in New York.
In the last ten years Professor Ronco was asked to deliver lectures and seminars in several Universities.
He has delivered in meetings and seminars more than 300 lectures and presentations.

In 1982 he introduced in Italy the use of continuous hemofiltration and in 1986 he published the first series of neonates treated with arteriovenous hemofiltration.
In 1985 He contributed to the introduction in Europe of high flux dialysis and derived therapies. He also established the dangerous effect of backfiltration in a contaminated dialysis fluid condition.
He has conducted a series of clinical and experimental researches in the following fields:
- Kinetics of fluid and solute removal in peritoneal dialysis and hemodialysis
- Treatment of Acute renal failure with intermittent and continuous therapies
- Renal replacement therapy in the neonate
- Development of new treatment modalities for acute and chronic renal failure.
- Studies on biomaterials
- Studies on glomerular filtration in humans and renal functional reserve
- Renal physiology in pregnancy
- Hydraulics and flow dynamics in the extracorporeal circulation
- Adequacy of dialysis
- Acid-Base Balance in uremia and dialysis
- Acute renal failure and Critical Care Nephrology

Professional employement and Hospital appointments:
Assistant of clinical nephrology from 1977 to 1984 at Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Associate of clinical nephrology from 1984 at Department of Nephrology , St. Bortolo Hospital, Vicenza, Italy.
From 1984 he is director of the hemodialysis and peritoneal dialysis center of the Department of Nephrology at St. Bortolo Hospital, Vicenza, Italy.
From October 25, 1999 to December 1st 2000 Dr. Ronco has been Director of the research laboratory of Hemodialysis at the Beth Israel Medical center of New York and Visiting Professor of Medicine at the Albert Einstein College of Medicine of new York
Today Dr. Ronco is director of the Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.

Board certification: In 1989 he has achieved in Rome, the National License for Nephrology Chair and Directional Functions, with the score 94/100.

Professional Society Membership: He is mamber of the council of several scientific societies and he is editor in chief of the international journal of artificial organs and contributions to nephrology.

Awards and honors:
1983 Schwartz Award, for the best paper of the year at St. Bortolo Hospital.
1984 G.F. Volpato Grant for the best research project on acute renal failure in Italy
1989 Best paper Prize at the Italian Society of nephrology meeting.
1991 ESAO RESEARCH AWARD for the best paper presented at the European Society for Artificial Organs.
1996 Arturo Borsatti Award of Padova University as a best nephrologist of the year.
2004 Lifetime achievement award

Other professional activities: He has organized several congresses and meetings in the area of nephrology and Intensive care from 1982 to today.
He is member of several advisory groups for clinical trials and dialysis research.

Lectures and publications: Dr. Ronco has coauthored 560 papers, 36 book chapters, 26 books, 7 monographic journal issues and has delivered more than 300 lectures in international meetings and universities. His personal impact factor calculated at december 2002 is 391.
3:30-4:00
Coffee Break
Plenary 2 MINI-SYMPOSIA
Acute Kidney Injury (AKI): Pathophysiology
4:00-6:00

Jay Koyner, MD

Dr. Koyner is an Associate Professor of Medicine in the Section of Nephrology at the University of Chicago. He completed his Internal Medicine and Nephrology training at the University of Chicago Medical Center where he currently serves as the medical director of the Inpatient Dialysis Unit and Director of ICU Nephrology. His critical care nephrology research interests have focused on the utilization of plasma and urine biomarkers to improve patient risk stratification and outcomes in the setting of AKI. In addition to biomarkers, other research interests include predictive analytics, AKI following cardiac surgery, CRRT and AKI therapeutics. He has published over 80 peer-reviewed articles and book chapters on AKI and the care of patients in with kidney injury in the ICU.

Bruce Molitoris, MD

Bruce A. Molitoris, M.D. is a Professor of Medicine, Director of Nephrology and Director of the Indiana Center for Biological Microscopy at Indiana University School of Medicine. He received his M.D. Degree from Washington University in St. Louis and his Nephrology Fellowship training at the University of Colorado. His active areas of research interest include Acute Kidney Injury, Toxic Nephropathy and Microscopic Imaging Techniques.
4:00-4:15
Is Atypical HUS Masquerading as Sepsis-induced AKI?
Room: Coronado Ballroom

John Kellum, MD

John A. Kellum, MD, FACP, MCCM John A. Kellum, MD, MCCM is Professor of Critical Care Medicine, Medicine, Bioengineering and Clinical and Translational Science, and Vice Chair for Research within the Department of Critical Care Medicine and Director of the Center for Critical Care Nephrology at the University of Pittsburgh. Dr. Kellum received his medical degree from the Medical College of Ohio in 1984. His postgraduate training includes an internship and residency in Internal Medicine at the University of Rochester, NY, and a Fellowship in Critical Care Medicine at the University of Pittsburgh Medical Center. Dr. Kellum is actively involved in education, research and administration. Dr. Kellum’s research interests span various aspects of Critical Care Medicine, but center in critical care nephrology, sepsis and multi-organ failure, and clinical epidemiology, including consensus development and research methodology. He has authored more than 250 publications and has won several awards for teaching. He lectures widely and has given more than 300 seminars and invited lectures worldwide related to his research.
4:15-4:30
Extracellular Vesicles in AKI: What do They Tell Us?

Vincenzo Cantaluppi, MD

Vincenzo Cantaluppi is Associate Professor of Nephrology at tbe University of Eastern Piedmont “A. Avogadroâ€, “Maggiore della Carità†University Hospital in Novara, Italy. He is the Director of Nephrology and Kidney Transplantation Unit at the University of Eastern Piedmont. He is an active clinical investigator in the fields of acute kidney injury, renal replacement therapy in intensive care unit, kidney transplantation. His main lines of basic research are focused on acute kidney injury biomarkers and on development of new potential therapeutic strategies for acute kidney injury based on transplantation of stem cells and derived extracellular vesicles.
4:30-4:45
AKI in Neonates: Lessons Learnt

David Askenazi, MD, MSPH

Dr. Askenazi is the Medical Director of the Pediatric and Infant Center for Acute Nephrology (PICAN), whose mission is to impove the outcomes of infants and children at risk for acute kidney disease by performing excellent comprehensive multi-disciplinary care, research and education. Dr. Askenazi's research interest include: a) the role that acute kidney injury (AKI) has on short and long-term outcomes in neonates and pediatric patients, b) testing therapies to improve the short and long-term outcomes of neonates and pediatric patients with AKI, and c) improving the definition of neonatal AKI using urinary and serum biomarkers of AKI.
4:45-5:00
Urinary Sediments in AKI Detection and Differentiation

Li Yang, MD

Dr. Yang is an Associate Professor of Medicine in the Renal Division of Peking University First Hospital and Associate Director in the Institute of Nephrology at Peking University, where she directs clinical acute kidney injury, renal pathology, and basic research in nephrology. She is committee member of the International Society of Nephrology Commission on Acute Renal Failure. She received the M.D. degree from Peking University in 2001, and has been on the faculty at Peking University First Hospital since 2001. She was a Research Fellow, granted by the International Society of Nephrology, in the renal division of Brigham and Women’s Hospital at Harvard Medical School, from 2007-2010. Her research interests are in the fields of acute kidney injury, drug associated kidney diseases and renal pathology.
5:00-5:15
Role of Repair Biomarkers in AKI

Chirag Parikh, MD, PhD

Chirag R. Parikh, MD, PhD, FACP, FASN, is an Associate Professor of Medicine in the Section of Nephrology, Associate Professor of Investigative Medicine, and Director, Program of Applied Translational Research, at Yale University School of Medicine. He is also an Associate Professor in the Clinical Epidemiology Research Center at the VA Connecticut Health Care System. His principal research interests focus on the translation and validation of novel biomarkers for the diagnosis and prognosis of acute kidney injury. Dr. Parikh completed the largest validation study of urinary biomarkers in which more than 10,000 samples were collected for the measurement of biomarkers for early diagnosis and prognosis of AKI after cardiac surgery. In 2005, he founded TRIBE-AKI (Translational Research Investigating Biomarker Endpoints in AKI)—a consortium of researchers across several states which have enrolled over 2500 patients in three cohort studies. TRIBE-AKI has yielded groundbreaking, nationally recognized achievements in biomarker discovery and validation, and its success led to establishment of the Program of Applied Translational Research in 2012. The program is comprised of a multidisciplinary team of talented physicians and scientists committed to patient-oriented research and improved outcomes in clinical medicine and disease management. As Director of PATR, Dr. Parikh oversees several NIH-sponsored, multicenter studies testing biomarkers in the areas of cardiac surgery, kidney transplantation, aging, HIV, and hepatorenal syndrome.
5:15-5:30
Mechanisms of Drug Induced AKI

Melanie Joy, PharmD, PhD

Dr. Joy is an accomplished translational researcher having spent the last 24+ years as a researcher and clinician in nephrology, pharmacology, and pharmaceutics. Dr. Joy spent the last ~6 years at the University of Colorado and is now a tenured Associate Professor in the Skaggs School of Pharmacy and Pharmaceutical Sciences, with a joint appointment in the School of Medicine Division of Nephrology. Previously, Dr. Joy spent 16 years at the University of North Carolina (UNC) where she was an Associate Professor of Medicine (Nephrology) and Pharmacy. Dr. Joy has consulted with numerous pharmaceutical companies on study design and has served on pharmaceutical advisory boards. Dr. Joy has conducted over 60 studies (NIH, foundation, and pharmaceutical company funded) investigating new drugs and devices in the kidney disease population and was Director of the UNC Nephrology Clinical Trials program from 1998 to 2003. She has subsequently focused on her investigator initiated and NIH funded research. Her lab is currently funded by two NIH R01 grants. Dr. Joy has published 86 articles, 21 book chapters, and over 90 abstracts. Dr. Joy is experienced in the conduct of renal pharmacology studies related to acute and chronic kidney diseases. Dr. Joy has led and managed a chronic kidney disease clinic that focused on the treatments of kidney disease complications including phosphorus management and anemia. Professional activities have included US FDA Cardiovascular and Renal Drugs Advisory Committee Member, USP Nephrology and Urology Expert Committee member, NIH NIDDK Ad Hoc reviewer for numerous study sections, several American Society of Nephrology committees and initiatives, a Kidney Health Initiative (KHI) stakeholder, American College of Clinical Pharmacy (ACCP) Leadership Institute, and UNC Mid-Career Leadership Initiative. Dr. Joy has extensive connections to clinicians, researchers, industry, and professional organizations in the nephrology area.
5:30-6:00
SPECIAL LECTURE
Informatics in Disease Management: What Will the Future Hold?
TBD

Mike Hogarth, MD

6:00
Adjourn
6:00-8:00
Exhibit Reception and Poster Session

Thursday, Morning, February 28

7:00am-4:30pm
Registration Open
7:00-8:00
Coffee Served
7:00-8:15
ME3 MEET THE EXPERT
How I Use AKI Biomarkers in My Practice

Claudio Ronco, MD

Actual Position:
Dr. Claudio Ronco
Director
Department of Nephrology
St. Bortolo Hospital
Viale Rodolfi 16
I-36100 Vicenza
Italy

Name: Claudio Ronco

Date of birth: July 12, 1951

Education: High School Diploma at Vicenza Classic Lyceum “A.Pigafetta” in 1970 with the score: 45/60. Dr. Ronco Graduated in Medicine at University of Padua in 1976 with the score 110/110 and merit debating an experimental thesis on title “ Aspects of the Nitrogen metabolism in the nephrotic syndrome”.
From 1973 to 1976 has been intern at Institute of Clinical Internal Medicine I^ of the University of Padua, directed by Prof. E. Fiaschi, in the Nephrology Department II, under the supervision of the Prof. G. Maschio.

Postgraduate training: From July 1976 to November 1977 he has been internal resident at the Division of Internal Medicine of the St. Bortolo Hospital in Vicenza, directed by Prof. D. Corà.
In 1979 he has achieved the Specialization Diploma on Medical Nephrology at The postgraduate school of internal medicine of the University of Padua, with the score 70/70 debating a thesis on the “new methodologies for the measurement of the urinary bicarbonate”
In 1989 he has achieved the Diploma of Specialization in Pediatric Nephrology at University of Naples.
1982: Visiting Fellow at the Mount Sinai Hospital in New York, Department of Internal medicine, Nephrology Division, for four months. He carried out studies on hemofiltration and glomerular filtration with J.P. Bosh, S. Glabman and M. Levitt.
1984: Visiting Physician at the Mount Sinai Hospital In New York for two weeks and at VA Hospital in Los Angeles for two weeks.
1985: Visiting professor at the Nephrology Division of the George Washington University Hospital, Washington DC, and NIH at National Naval Medical Center of Bethesda for three months.
1988: Visiting professor at the Renal and Hypertension Division of George Washington University for three months.
1991: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
1995: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.

Teaching acitivity and Academic Qualifications: From 1978 to 1984 he has been in charge of the teaching program of Nephrology and Dialysis at Professional Nursing School in Vicenza.
During the academic years 1989-01 he has been in charge of teaching “Dialytic therapy” at Specialization School in Medical Nephrology of Padua University where he holds a post of Professor of Nephrology in charge of the teaching program concerning Hemodialysis and renal replacement therapies in critically ill patients.
October 1999-December 2000: Professor of Medicine at Albert Einstein College of Medicine and Director of the Renal laboratory at the Beth israel Medical Center in New York.
In the last ten years Professor Ronco was asked to deliver lectures and seminars in several Universities.
He has delivered in meetings and seminars more than 300 lectures and presentations.

In 1982 he introduced in Italy the use of continuous hemofiltration and in 1986 he published the first series of neonates treated with arteriovenous hemofiltration.
In 1985 He contributed to the introduction in Europe of high flux dialysis and derived therapies. He also established the dangerous effect of backfiltration in a contaminated dialysis fluid condition.
He has conducted a series of clinical and experimental researches in the following fields:
- Kinetics of fluid and solute removal in peritoneal dialysis and hemodialysis
- Treatment of Acute renal failure with intermittent and continuous therapies
- Renal replacement therapy in the neonate
- Development of new treatment modalities for acute and chronic renal failure.
- Studies on biomaterials
- Studies on glomerular filtration in humans and renal functional reserve
- Renal physiology in pregnancy
- Hydraulics and flow dynamics in the extracorporeal circulation
- Adequacy of dialysis
- Acid-Base Balance in uremia and dialysis
- Acute renal failure and Critical Care Nephrology

Professional employement and Hospital appointments:
Assistant of clinical nephrology from 1977 to 1984 at Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Associate of clinical nephrology from 1984 at Department of Nephrology , St. Bortolo Hospital, Vicenza, Italy.
From 1984 he is director of the hemodialysis and peritoneal dialysis center of the Department of Nephrology at St. Bortolo Hospital, Vicenza, Italy.
From October 25, 1999 to December 1st 2000 Dr. Ronco has been Director of the research laboratory of Hemodialysis at the Beth Israel Medical center of New York and Visiting Professor of Medicine at the Albert Einstein College of Medicine of new York
Today Dr. Ronco is director of the Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.

Board certification: In 1989 he has achieved in Rome, the National License for Nephrology Chair and Directional Functions, with the score 94/100.

Professional Society Membership: He is mamber of the council of several scientific societies and he is editor in chief of the international journal of artificial organs and contributions to nephrology.

Awards and honors:
1983 Schwartz Award, for the best paper of the year at St. Bortolo Hospital.
1984 G.F. Volpato Grant for the best research project on acute renal failure in Italy
1989 Best paper Prize at the Italian Society of nephrology meeting.
1991 ESAO RESEARCH AWARD for the best paper presented at the European Society for Artificial Organs.
1996 Arturo Borsatti Award of Padova University as a best nephrologist of the year.
2004 Lifetime achievement award

Other professional activities: He has organized several congresses and meetings in the area of nephrology and Intensive care from 1982 to today.
He is member of several advisory groups for clinical trials and dialysis research.

Lectures and publications: Dr. Ronco has coauthored 560 papers, 36 book chapters, 26 books, 7 monographic journal issues and has delivered more than 300 lectures in international meetings and universities. His personal impact factor calculated at december 2002 is 391.

Alex Zarbock, MD

Dr. Zarbock is a Clinician Scientist and the Director and Chair of the Department of Anesthesiology and Critical Care Medicine, at the University of Münster, Germany. He acquired training at the University of Münster (Anesthesiology and Critical Care Medicine). Dr. Zarbock is supported by the German Research Foundation. His research interests span various aspects of Critical Care Medicine, but center in critical care nephrology (renal replacement therapy), sepsis and organ protection. Dr. Zarbock’s current projects include measures to avoid acute kidney injury after surgery and the timing of renal replacement therapy in critically ill patients with acute kidney injury. He is also author and co-author of over 140 scientific articles and book chapters.
7:00-8:15
ME4 MEET THE EXPERT
What Blood Pressure do I Target in My ICU Patients?

John Kellum, MD

John A. Kellum, MD, FACP, MCCM John A. Kellum, MD, MCCM is Professor of Critical Care Medicine, Medicine, Bioengineering and Clinical and Translational Science, and Vice Chair for Research within the Department of Critical Care Medicine and Director of the Center for Critical Care Nephrology at the University of Pittsburgh. Dr. Kellum received his medical degree from the Medical College of Ohio in 1984. His postgraduate training includes an internship and residency in Internal Medicine at the University of Rochester, NY, and a Fellowship in Critical Care Medicine at the University of Pittsburgh Medical Center. Dr. Kellum is actively involved in education, research and administration. Dr. Kellum’s research interests span various aspects of Critical Care Medicine, but center in critical care nephrology, sepsis and multi-organ failure, and clinical epidemiology, including consensus development and research methodology. He has authored more than 250 publications and has won several awards for teaching. He lectures widely and has given more than 300 seminars and invited lectures worldwide related to his research.

Patrick Murray, Prof

Patrick Murray is Professor of Clinical Pharmacology in University College Dublin, and a consultant physician (clinical pharmacologist & nephrologist) at the Mater Misericordiae University Hospital, Dublin, Ireland. He received his medical education at University College Dublin, Ireland. Following his internship at the Mater Misericordiae University Hospital in Dublin, he completed a residency in internal medicine at Hennepin County Medical Center in Minneapolis, Minnesota, USA. He completed fellowship training programs in nephrology, critical care medicine, and clinical pharmacology at the University Of Chicago Hospitals in Chicago, Illinois, USA. He is board-certified in nephrology, critical care medicine, and clinical pharmacology. He practiced as an intensivist, nephrologist, and clinical pharmacologist at the University of Chicago Hospitals from 1996–2008, serving as the fellowship training program director in nephrology, also directing the Acute Dialysis Service. He has a longstanding interest in research and education to improve the prevention, diagnosis, and therapy of acute kidney injury and nephrotoxicity, and the pharmacotherapy of patients with kidney disease. He is a member of several international consensus groups that have produced guidelines for research and practice in the field of acute kidney injury (ADQI, AKIN, KDOQI). Since 2008, he has been the Professor of Clinical Pharmacology at University College Dublin, and a Consultant in Nephrology & Clinical Pharmacology at the Mater Misericordiae University Hospital. He is Chair of the Mater Misericordiae University Hospital Drugs & Therapeutics Committee. He is the Clinical Director of the UCD-Mater Clinical Research Centre. In 2011, he was appointed Associate Dean for International Affairs in the UCD School of Medicine and Medical Science. In 2012, he was appointed Director of the Dublin Centre for Clinical Research (DCCR) Consortium Network, and also Clinical Director of the Irish Clinical Research Infrastructure Network (ICRIN). Since December 2012, he has been the Dean and Head of the School of Medicine at UCD.
Breakfast Symposia listed below are hosted by Conference (RSVP Required)
Selection made during registration
Breakfast Symposia
7:00-8:15
7:00-8:15
Breakfast Symposium C
Innovations in Caring for Patients with Dysnatremias
CME Available
Dysnatremias are commonly encountered in ICU patients and are often difficult to manage. This symposium will cover the pathophysiology of hypo and hypernatremia and discuss the practical issues for management of these disorders with novel agents and describe how RRT can be used for severe disorders.e
Kashani (Moderator), Qian and Lewington (Discussants)

Kianoush Kashani, MD

Kianoush Kashani, MD is a consultant in the Division of Nephrology and Hypertension, Division of Pulmonary and Critical Care at Mayo Clinic, Rochester. His academic rank is Professor in Internal Medicine and Assistant Professor in Medical Education. His research interest is acute kidney injury, electrolyte disorders, simulation medicine, and critical care point-of-care ultrasonography.

Andrew Lewington, MD

Dr Andrew Lewington studied medicine as an undergraduate in London before pursuing a career in renal medicine. He studied in Leicester UK and Washington University USA where he worked in Mark Hammermann's laboratory investigating the molecular mechanisms underlying ischaemic acute kidney injury.Dr Lewington was appointed consultant renal physician/honorary senior lecturer at Leeds Teaching Hospitals in 2004. He works as an NHS clinician providing a specialist renal opinion on acutely ill patients on the ICU across Leeds. He was an expert adviser on the UK NCEPOD adding insult to injury AKI study, working from his position on the Renal Association executive committee to improve the care that patients who develop AKI receive. He is the lead author of the 5th Renal Association AKI clinical practice guidelines. During his time in Leeds he has developed collaborative research with an internationally recognised proteomics group. He currently has a nephrology fellow investigating potential proteomic biomarkers of kidney dysfunction in the early phase following kidney transplantation. He is Clinical Sub Dean for the Leeds Teaching Hospitals and is heavily involved in the delivery of undergraduate medical education at the University of Leeds.

Qi Qian, MD

Dr. Qi Qian is a faculty nephrologist and Professor of Medicine and Professor of Physiology at the Mayo Clinic College of Medicine and Mayo Graduate School, USA. She is the Director of the Mayo Clinic Rochester Nephrology Hospital Practice. She is also an adjunct Professor of Medicine at four top universities in China (Nanjing University School of Medicine in Nanjing, Fourth Military Medical University in Xi’an, Zhejiang University in Hangzhou, and Fudan University, Shanghai, China) A graduate of the Shanghai 2nd Medical University, Dr. Qian received her post-graduate training in medicine and nephrology at the Albert Einstein College of Medicine, Bronx, New York and was recruited to join the staff at Mayo Clinic upon her graduation from fellowship training in 1999. Dr. Qian's professional focus is on patient care, clinical/translational research and education in the area of renal tubular disorders. In the years of 2000-2008, she conducted basic science research on the renal/vascular pathophysiology through funding from Mayo Clinic Foundation and the National Institutes of Health (NIH-NIDDK). Her expertise in renal and vascular physiology and pathophysiology adds an important dimension to her management of patients with renal tubular diseases. Dr. Qian also heads the Mayo Clinic Acid-Base Electrolyte Interest Group. She is the principal investigator on a number of studies investigating the effects of electrolyte alterations and renal tubular function. Dr. Qian is an award-winning educator at Mayo Clinic. She has mentored a large number of trainees and is an author and content expert for “AskMayoExpertâ€, a popular Mayo Clinic web-based medical practice reference for clinicians all over the United States. She currently serves as the president of the Chinese American Society of Nephrology and an ISN Educational Ambassador.
7:00-8:15
Breakfast Symposium D
Managing AKI in the Patient with Cancer
CME Available
The number of anticancer drugs are increasingly expanding and commonly cause kidney injury. This symposium will discuss how to prevent drug nephrotoxicity, adjust doses of anticancer medicines and manage patients who develop AKI in the setting cancer therapy.
Ostermann (Moderator), Rosner and Joy (Discussants)

Melanie Joy, PharmD, PhD

Dr. Joy is an accomplished translational researcher having spent the last 24+ years as a researcher and clinician in nephrology, pharmacology, and pharmaceutics. Dr. Joy spent the last ~6 years at the University of Colorado and is now a tenured Associate Professor in the Skaggs School of Pharmacy and Pharmaceutical Sciences, with a joint appointment in the School of Medicine Division of Nephrology. Previously, Dr. Joy spent 16 years at the University of North Carolina (UNC) where she was an Associate Professor of Medicine (Nephrology) and Pharmacy. Dr. Joy has consulted with numerous pharmaceutical companies on study design and has served on pharmaceutical advisory boards. Dr. Joy has conducted over 60 studies (NIH, foundation, and pharmaceutical company funded) investigating new drugs and devices in the kidney disease population and was Director of the UNC Nephrology Clinical Trials program from 1998 to 2003. She has subsequently focused on her investigator initiated and NIH funded research. Her lab is currently funded by two NIH R01 grants. Dr. Joy has published 86 articles, 21 book chapters, and over 90 abstracts. Dr. Joy is experienced in the conduct of renal pharmacology studies related to acute and chronic kidney diseases. Dr. Joy has led and managed a chronic kidney disease clinic that focused on the treatments of kidney disease complications including phosphorus management and anemia. Professional activities have included US FDA Cardiovascular and Renal Drugs Advisory Committee Member, USP Nephrology and Urology Expert Committee member, NIH NIDDK Ad Hoc reviewer for numerous study sections, several American Society of Nephrology committees and initiatives, a Kidney Health Initiative (KHI) stakeholder, American College of Clinical Pharmacy (ACCP) Leadership Institute, and UNC Mid-Career Leadership Initiative. Dr. Joy has extensive connections to clinicians, researchers, industry, and professional organizations in the nephrology area.

Marlies Ostermann, MD

Dr Ostermann is a Consultant in Critical Care & Nephrology at Guy’s & St Thomas’ Foundation Trust, London and Honorary Senior Lecturer at King’s College London. After medical school in Goettingen (Germany), she did her postgraduate training in London and Canada. She holds a PhD degree from the University of Goettingen, an MD degree from the University of London and a postgraduate Diploma in Medical Education. She is an active member of the European Society of Intensive Care Society, Renal Association and Intensive Care Society UK, and a Fellow of the Faculty of Intensive Care Medicine. She is also a co-founder of the London AKI Network. Her research interests include acute kidney injury in critically ill and all aspects of renal replacement therapy.

Mitchell Rosner, MD

Dr. Rosner is currently the Henry B. Mulholland Professor of Medicine at the University of Virginia School of Medicine as well as the Chairman of the Department of Medicine. Dr. Rosner serves on the executive committee of training program directors for the American Society of Nephrology. His research interests include: sodium and water metabolism and acute kidney injury. He is a fellow of the American Society of Nephrology and a fellow of the American College of Physicians
Standard Workshop Group 3
8:15-9:45
8:15-9:45
A13 Preventing AKI: From Surveillance to Intervention (C,N,AP)
This workshop will describe the current status of methods to identify patients at high risk for AKI and techniques for electronic surveillance. Strategies and tools for preventing AKI in different settings will be discussed.

Rajit Basu, MD MS FCCM

Dr. Basu is dedicated to improving the recognition, treatment, and outcomes of critically ill children suffering acute kidney injury. As Co-Director of the Center for Acute Care Nephrology at Cincinnati Children's Hospital, Dr. Basu oversees projects in the pediatric intensive care unit investigating AKI prediction by risk stratified optimization of biomarkers (renal angina), biomarker and fluid overload directed renal replacement therapy initiation, and use of the EMR to provide clinical decision support for management of AKI and fluid balance. Prior to arriving at Cincinnati Children's in 2009, Dr. Basu completed his Pediatric Critical Care fellowship and Pediatric residency at Northwestern University in Chicago. Originally from South Bend, Indiana, he is a graduate of Indiana University Medical School and the University of Notre Dame (undergraduate degree in Biochemistry).

Kianoush Kashani, MD

Kianoush Kashani, MD is a consultant in the Division of Nephrology and Hypertension, Division of Pulmonary and Critical Care at Mayo Clinic, Rochester. His academic rank is Professor in Internal Medicine and Assistant Professor in Medical Education. His research interest is acute kidney injury, electrolyte disorders, simulation medicine, and critical care point-of-care ultrasonography.

Andrew Lewington, MD

Dr Andrew Lewington studied medicine as an undergraduate in London before pursuing a career in renal medicine. He studied in Leicester UK and Washington University USA where he worked in Mark Hammermann's laboratory investigating the molecular mechanisms underlying ischaemic acute kidney injury.Dr Lewington was appointed consultant renal physician/honorary senior lecturer at Leeds Teaching Hospitals in 2004. He works as an NHS clinician providing a specialist renal opinion on acutely ill patients on the ICU across Leeds. He was an expert adviser on the UK NCEPOD adding insult to injury AKI study, working from his position on the Renal Association executive committee to improve the care that patients who develop AKI receive. He is the lead author of the 5th Renal Association AKI clinical practice guidelines. During his time in Leeds he has developed collaborative research with an internationally recognised proteomics group. He currently has a nephrology fellow investigating potential proteomic biomarkers of kidney dysfunction in the early phase following kidney transplantation. He is Clinical Sub Dean for the Leeds Teaching Hospitals and is heavily involved in the delivery of undergraduate medical education at the University of Leeds.
8:15-9:45
B14 Personalized Fluid Management with CRRT (A)
Achieving fluid balance and maintaining plasma composition is key for effective CRRT. This workshop will use case studies to discuss strategies for fluid management in CRRT to achieve patient driven outcomes for fluid, electrolyte and acid base balance.

Ravindra Mehta, MBBS, MD, DM, FACP

Dr. Mehta is Professor of Medicine in the Division of Nephrology and Associate Chair for Clinical Affairs in the Department of Medicine at the University of California, San Diego (UCSD) where he directs the Clinical nephrology and dialysis programs. He is also the Chair of the International Society of Nephrology Commission on Acute Renal Failure, founding member of the Acute Dialysis Quality Initiative. He received the M.B.B.S. degree (1976) from the Government Medical School in Amritsar, India, and the M.D. (1979) and D.M. (1981) degrees from the Post Graduate Institute of Medical Education and Research in Chandigarh, India. He subsequently completed a nephrology fellowship at the University of Rochester in Rochester New York and obtained his boards in internal medicine (1986) and Nephrology (1988). He has been on the faculty at San Diego since 1988. His reserach interests are in the field of acute renal failure and he has directed several clinical studies in the management of patients with ARF including comparing different dialytic modalities, conducting large multicenter observational studies of ARF with the PICARD group, evaluating different predictive models for outcomes in ARF, investigating the role of cytokine removal by dialysis membranes in sepsis and ARF, and evaluating techniques for determining the amount of excess fluid in dialysis patients.

John Prowle, MA MSc MD FRCP FFICM

Dr Prowle is a Senior Clinical Lecturer in Intensive Care Medicine within the Critical Care and Perioperative Medicine Research Group at Barts and the London School of Medicine and Dentistry, Queen Mary University of London and is an Honorary Consultant Physician in Intensive Care Medicine and Nephrology at the Royal London Hospital, Barts Health NHS Trust, London, UK. He graduated in medicine from the University of Cambridge in 1999 and undertook Doctoral Research under the supervision of Prof Rinaldo Bellomo in Melbourne, Australia leading to the award of his research doctorate in 2013. Dr Prowle’s academic interests include the Pathogenesis, Diagnosis and Treatment and Outcomes of Acute Kidney Injury, Continuous Renal Replacement Therapies in the ICU, Fluid Therapy and Medical Complications of Major Surgery. Since 2009 he has co-authored over 80 peer-reviewed publications and book chapters, including chapters related to Acute Kidney Injury in the latest editions of the Oxford Textbook of Clinical Nephrology and the Oxford Textbook of Critical Care.
8:15-9:45
C15 Drug Dosing in RRT: Management Strategies (A,N)
Patients receiving RRT in the ICU are in multiple drugs which are affected by the procedures and require adjustments to ensure an adequate exposure. This workshops will focus on the principles for appropriate drug dosing and adjustments in patients on RRT.

Stuart Goldstein, MD

Dr. Goldstein serves as Director for the Center for Acute Care Nephrology (CACN) at Cincinnati Children's Hospital Medical Center. The CACN's mission is to coordinate all AKI related clinical, research and outcomes efforts at CCHMC and to function as a nexus for coordinating multi-center pediatric AKI research. Dr. Goldstein is the Founder and Principal Investigator of the Prospective Pediatric AKI Research Group (www.ppaki.org), a 50 center international pediatric acute care nephrology research consortium that will focuses on pediatric AKI epidemiology, interventional trials, device evaluation and genetic studies. Dr. Goldstein is also the program director for the only Pediatric Acute Care Nephrology fellowship in the United States.

Melanie Joy, PharmD, PhD

Dr. Joy is an accomplished translational researcher having spent the last 24+ years as a researcher and clinician in nephrology, pharmacology, and pharmaceutics. Dr. Joy spent the last ~6 years at the University of Colorado and is now a tenured Associate Professor in the Skaggs School of Pharmacy and Pharmaceutical Sciences, with a joint appointment in the School of Medicine Division of Nephrology. Previously, Dr. Joy spent 16 years at the University of North Carolina (UNC) where she was an Associate Professor of Medicine (Nephrology) and Pharmacy. Dr. Joy has consulted with numerous pharmaceutical companies on study design and has served on pharmaceutical advisory boards. Dr. Joy has conducted over 60 studies (NIH, foundation, and pharmaceutical company funded) investigating new drugs and devices in the kidney disease population and was Director of the UNC Nephrology Clinical Trials program from 1998 to 2003. She has subsequently focused on her investigator initiated and NIH funded research. Her lab is currently funded by two NIH R01 grants. Dr. Joy has published 86 articles, 21 book chapters, and over 90 abstracts. Dr. Joy is experienced in the conduct of renal pharmacology studies related to acute and chronic kidney diseases. Dr. Joy has led and managed a chronic kidney disease clinic that focused on the treatments of kidney disease complications including phosphorus management and anemia. Professional activities have included US FDA Cardiovascular and Renal Drugs Advisory Committee Member, USP Nephrology and Urology Expert Committee member, NIH NIDDK Ad Hoc reviewer for numerous study sections, several American Society of Nephrology committees and initiatives, a Kidney Health Initiative (KHI) stakeholder, American College of Clinical Pharmacy (ACCP) Leadership Institute, and UNC Mid-Career Leadership Initiative. Dr. Joy has extensive connections to clinicians, researchers, industry, and professional organizations in the nephrology area.

Patrick Murray, Prof

Patrick Murray is Professor of Clinical Pharmacology in University College Dublin, and a consultant physician (clinical pharmacologist & nephrologist) at the Mater Misericordiae University Hospital, Dublin, Ireland. He received his medical education at University College Dublin, Ireland. Following his internship at the Mater Misericordiae University Hospital in Dublin, he completed a residency in internal medicine at Hennepin County Medical Center in Minneapolis, Minnesota, USA. He completed fellowship training programs in nephrology, critical care medicine, and clinical pharmacology at the University Of Chicago Hospitals in Chicago, Illinois, USA. He is board-certified in nephrology, critical care medicine, and clinical pharmacology. He practiced as an intensivist, nephrologist, and clinical pharmacologist at the University of Chicago Hospitals from 1996–2008, serving as the fellowship training program director in nephrology, also directing the Acute Dialysis Service. He has a longstanding interest in research and education to improve the prevention, diagnosis, and therapy of acute kidney injury and nephrotoxicity, and the pharmacotherapy of patients with kidney disease. He is a member of several international consensus groups that have produced guidelines for research and practice in the field of acute kidney injury (ADQI, AKIN, KDOQI). Since 2008, he has been the Professor of Clinical Pharmacology at University College Dublin, and a Consultant in Nephrology & Clinical Pharmacology at the Mater Misericordiae University Hospital. He is Chair of the Mater Misericordiae University Hospital Drugs & Therapeutics Committee. He is the Clinical Director of the UCD-Mater Clinical Research Centre. In 2011, he was appointed Associate Dean for International Affairs in the UCD School of Medicine and Medical Science. In 2012, he was appointed Director of the Dublin Centre for Clinical Research (DCCR) Consortium Network, and also Clinical Director of the Irish Clinical Research Infrastructure Network (ICRIN). Since December 2012, he has been the Dean and Head of the School of Medicine at UCD.
8:15-9:45
D16 Managing the Heart Failure Patient with Worsening Renal Function (WRF) (A,N)
Patients with advanced heart failure often develop WRF. It is often difficult to determine which patients can be managed with drug therapy vs requiring RRT. This workshop will describe the practical application and results of different methods to treat heart failure and cardio-renal syndrome including ultrafiltration techniques.

Salvatore diSomma, Professor of Medicin

Name: Salvatore Surname: Di Somma Place and date of birth: Naples (Italy), 7.6.1953. Graduate in Medicine “cum laude†(University of Naples), 1978. Post Graduate “cum Laude†in Internal Medicine (University of Naples), 1983. Post Graduate “cum Laude†in Cardiology (University of Naples), 1987. Current Position Professor of Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome, Department of Medical-Surgery Sciences and Translational Medicine since 2002. Chairman Postgraduate School of Emergency Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome, since 2002. Professor Postgraduate Schools of Internal Medicine and Cardiovascular Diseases Academic Positions Research Fellow - Department of Clinical and Experimental Medicine ’University “Federico II†of Naples from 1978 to 2001. Assistant Professor – Emergency Medicine and Cardioangiology – University Federico II of Naples, from 1978 al 2001. Research Fellow in Cardiology University of Pavia, 1989-1992. Assistant Professor Department of Medicine New York Medical College New York U.S.A. 1994-1996 Cardiovascular Research Institute. Minisrty of Health World Class Professor Programme , Brawijaya University Malang(Indonesia) Expert Professor in Medicinea and Cardiovascular Prevention;University of Lund (Malmoe (Sweden) Visiting Professor-Scholar Researcher -UCSD University California San Diego(USA) Scientific Societies Membership President of GREAT Network Italy President Scientific Committee of AISC (Italian Association of Patients with Heart Failure) Former President of GREAT Global Research on Acute Conditions Team, the Academic Research and Educational Organizationhttp://www.greatnetwork.org/int/ gathering experts operating in the management of acute clinical conditions in the field of Critical care,Emergency Medicine and Cardiology in 78 countries Worldwide. Official Academic International Cooperation: More than 300 Papers/books in the field of Cardiology,Intensive Care and Emergency Medicine . More than 400 presentations, invited lectures and chairs at major international Congresses in the fields of Hypertension, Cardiology, Critical Care Medicine ,Internal Medicine and Emergency Medicine. He has worldwide expertice in Biomarkers in Acute Diseases and Prevention in Aging.

Peter McCullough, MD, MPH

Dr. McCullough is an internationally recognized leader in academic cardiology with over 800 published, scientific communications. He is the co-editor of Reviews in Cardiovascular Medicine and serves on the editorial boards of multiple specialty journals. Dr. McCullough has led and participated on multiple consensus and guidelines panels in the fields of cardiology, nephrology, and critical care medicine.
8:15-9:45
E17 Intraoperative RRT: Strategies for Success (I,N,AP)
NURSES TRACK (E Series)
When is RRT needed in the operating room? Practical issues in setting up and implementing a program will be discussed using a case based approach.

Linda Awdishu, PharmD, MAS

Linda Awdishu earned her Bachelors of Science in Pharmacy from the University of Toronto in 1999, Doctor of Pharmacy from the University of Colorado in 2008 and Masters of Clinical Research from the University of California in 2007. She is an Associate Clinical Professor of Pharmacy and Medicine at UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences. She maintains a clinical practice in the chronic kidney disease program. Her research program is focused on drug induced kidney injury.

Sean Bagshaw, MD, MSc, FRCPC

Dr. Bagshaw is a Clinician Scientist and Assistant Professor in the Division of Critical Care Medicine, at the University of Alberta in Edmonton, Alberta, Canada. He acquired training at the University of Calgary (Internal Medicine, Critical Care Medicine, Masters of Science Epidemiology) prior to completing a critical care nephrology fellowship in the Department of Intensive Care Medicine, at the Austin Hospital in Melbourne, Australia. Dr. Bagshaw is supported by a Canada Research Chair in Critical Care Nephrology and a Clinical Investigator Award from Alberta Innovates - Health Solutions. Dr. Bagshaw's main research interests have focused on the clinical, epidemiological and translational issues related to acute kidney injury and the application of extracorporeal blood purification in critically ill patients. Dr. Bagshaw's current projects include diuretic therapy in early acute kidney injury and factors related with the initiation of renal support in critically ill patients. He has published over 100 peer-reviewed papers, numerous book chapters, and peer-reviewed for over 20 medical journals. Dr. Bagshaw is a member of several organizations including the Canadian Critical Care Society, Canadian Critical Care Trials Group, Australia New Zealand Intensive Care Society, and the Acute Kidney Injury Network, and the Acute Dialysis Quality Initiative.

Noel Oabel, BSN, RN, CNN

I have over 23 years of nursing experience with the last 13 years specializing in chronic and acute dialysis setting. I work as assistant nurse manager at University of California San Diego Medical Center Acute Dialysis Unit with expertise in Continuous Renal Replacement Therapy, Peritoneal Dialysis, Intermittent Hemodialysis, Intraoperative SLED and Therapeutic Plasma Exchange.
8:15-9:45
F18 Pediatric AKI and CRRT: How do I Care for My Patient and My Program? (I,N,AP)
Review and discussion of best practices to develop your pediatric AKI and CRRT program, identify and treat your young patients with AKI, and to assure delivery of high-quality care in the pediatric setting.

Theresa Mottes, MSN, RN,CPNP-AC,CDN

Theresa Mottes has over 20 years of pediatric renal replacement therapy experience is both the critical care setting and the outpatient dialysis setting. She has been involved in research with acute kidney injury, continuous renal replacement therapies and simulation based education for CRRT training. Theresa currently is a nurse practitioner for critical care nephrology. Theresa is very active with ANNA, as the current Pediatric Specialty Practice Network facilitator. She has presented at both national and international conferences.

David Selewski, MD

I am an Assistant Professor in the Department of Pediatrics within the Division of Nephrology at the University of Michigan. I received my training in pediatrics and pediatric nephrology at the University of Michigan. My clinical and research interests include pediatric critical care nephrology including pediatric & neonatal acute kidney injury, fluid overload, and continuous renal replacement therapy.
9:45-10:15
Coffee Break


SESSION II: CONTROVERSIES IN CRITICAL CARE NEPHROLOGY

Plenary 3 MINI-SYMPOSIA
Challenges in ICU Management
10:00-12:15

Rajit Basu, MD MS FCCM

Dr. Basu is dedicated to improving the recognition, treatment, and outcomes of critically ill children suffering acute kidney injury. As Co-Director of the Center for Acute Care Nephrology at Cincinnati Children's Hospital, Dr. Basu oversees projects in the pediatric intensive care unit investigating AKI prediction by risk stratified optimization of biomarkers (renal angina), biomarker and fluid overload directed renal replacement therapy initiation, and use of the EMR to provide clinical decision support for management of AKI and fluid balance. Prior to arriving at Cincinnati Children's in 2009, Dr. Basu completed his Pediatric Critical Care fellowship and Pediatric residency at Northwestern University in Chicago. Originally from South Bend, Indiana, he is a graduate of Indiana University Medical School and the University of Notre Dame (undergraduate degree in Biochemistry).

John Prowle, MA MSc MD FRCP FFICM

Dr Prowle is a Senior Clinical Lecturer in Intensive Care Medicine within the Critical Care and Perioperative Medicine Research Group at Barts and the London School of Medicine and Dentistry, Queen Mary University of London and is an Honorary Consultant Physician in Intensive Care Medicine and Nephrology at the Royal London Hospital, Barts Health NHS Trust, London, UK. He graduated in medicine from the University of Cambridge in 1999 and undertook Doctoral Research under the supervision of Prof Rinaldo Bellomo in Melbourne, Australia leading to the award of his research doctorate in 2013. Dr Prowle’s academic interests include the Pathogenesis, Diagnosis and Treatment and Outcomes of Acute Kidney Injury, Continuous Renal Replacement Therapies in the ICU, Fluid Therapy and Medical Complications of Major Surgery. Since 2009 he has co-authored over 80 peer-reviewed publications and book chapters, including chapters related to Acute Kidney Injury in the latest editions of the Oxford Textbook of Clinical Nephrology and the Oxford Textbook of Critical Care.
10:15-10:30
Early Resuscitation of the Unstable Patient: When and How?
Room: Coronado Ballroom

John Louis Vincent, MD PhD

Professor Vincent is Professor of intensive care medicine at the University of Brussels (Université Libre de Bruxelles) and intensivist in the Department of Intensive Care at Erasme University Hospital in Brussels. He obtained his PhD degree at the University of Brussels in 1982. He is a Past-President of the World Federation of Societies of Intensive and Critical Care Medicine (WFSICCM), the European Society of Intensive Care Medicine (ESICM), the European Shock Society (ESS), the Belgian Society of Intensive Care Medicine (SIZ), and the International Sepsis Forum (ISF). He was a Council member of the Society of Critical Care Medicine (SCCM) from 2011-2013. He is member of the Belgian Royal Academy of Medicine. Dr. Vincent has signed more than 900 original articles, some 400 book chapters and review articles, 1000 original abstracts, and has edited 102 books. He is co-editor of the “Textbook of Critical Care†(Elsevier Saunders) and the “Encyclopedia of Intensive Care Medicine†(Springer). He is the editor-in-chief of Critical Care, Current Opinion in Critical Care, and ICU Management & Practice and member of the editorial boards of about 30 other journals, including Critical Care Medicine (senior editor), the American Journal of Respiratory and Critical Care Medicine (AJRCCM), PLoS Medicine, Lancet Infectious Diseases, Intensive Care Medicine, Shock, the Journal of Critical Care and Annals of Intensive Care. Dr Vincent has received several awards including the College Medalist Award of the American College of Chest Physicians, the Society Medal (lifetime award) of the European Society of Intensive Care Medicine,), the distinguished investigator Award and the Lifetime Achievement Award of the Society of Critical Care Medicine, and the prestigious Belgian scientific award of the FRS-FNRS (Prix Scientifique Joseph Maisin-Sciences biomédicales cliniques). His name appears more than 1000 times in Pubmed, and his work has been cited more than 140,000 times; his H-index is 156. In recognition for these achievements, he was awarded the title of Baron by King Albert II of Belgium in 2013.
10:30-10:45
Should Saline be Out of the ICU?

Matthieu LeGrand, Pr

Pr Matthieu Legrand is Professor of Anesthesiology and Critical care medicine. He holds a PhD in physiology. He Works in the Department of anesthesiology, Critical care and burn unit of St-Louis hospital, university Paris Diderot, France. He has carried preclinical and clinical research in the field of critical care medicine with a special interest in critical care nephrology, sepsis and in burn critical care. He has served as a reviewer for several peer-review journals and expert in the field of critical care for several commitees and task forces.
10:45-11:00
Fluid Overload - Iatrogenesis Imperfecta

David Selewski, MD

I am an Assistant Professor in the Department of Pediatrics within the Division of Nephrology at the University of Michigan. I received my training in pediatrics and pediatric nephrology at the University of Michigan. My clinical and research interests include pediatric critical care nephrology including pediatric & neonatal acute kidney injury, fluid overload, and continuous renal replacement therapy.
11:00-11:15
Mobilization in the ICU: Fact or Fantasy?

Noel Gibney, MB FRCP(C)

Current Position: Professor, Department of Critical Care Medicine,Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada. Medical School: University College Dublin, Ireland Internal Medicine/Nephrology: St. Vincents Hospital, Dublin, Ireland Pulmonary Medicine: University of Alberta, Edmonton, AB, Canada Critical Care Medicine: Harvard University, Cambridge, MA, USA Interests: CRRT, Sepsis, Information Technology
11:15-11:30
Deresuscitation in Critically Ill Patients with AKI

Sean Bagshaw, MD, MSc, FRCPC

Dr. Bagshaw is a Clinician Scientist and Assistant Professor in the Division of Critical Care Medicine, at the University of Alberta in Edmonton, Alberta, Canada. He acquired training at the University of Calgary (Internal Medicine, Critical Care Medicine, Masters of Science Epidemiology) prior to completing a critical care nephrology fellowship in the Department of Intensive Care Medicine, at the Austin Hospital in Melbourne, Australia. Dr. Bagshaw is supported by a Canada Research Chair in Critical Care Nephrology and a Clinical Investigator Award from Alberta Innovates - Health Solutions. Dr. Bagshaw's main research interests have focused on the clinical, epidemiological and translational issues related to acute kidney injury and the application of extracorporeal blood purification in critically ill patients. Dr. Bagshaw's current projects include diuretic therapy in early acute kidney injury and factors related with the initiation of renal support in critically ill patients. He has published over 100 peer-reviewed papers, numerous book chapters, and peer-reviewed for over 20 medical journals. Dr. Bagshaw is a member of several organizations including the Canadian Critical Care Society, Canadian Critical Care Trials Group, Australia New Zealand Intensive Care Society, and the Acute Kidney Injury Network, and the Acute Dialysis Quality Initiative.
11:30-11:45
Novel Bacteriophage Therapy for Critical Infections

Saima Aslam, MD

Dr Aslam is an Assistant Professor at the Division of Infectious Diseases at the University of California, San Diego (UCSD) and the Director of the Solid Organ Transplant Infectious Diseases service at the UCSD Medical Center. She obtained her medical degree with honors from the Aga Khan University in Karachi, Pakistan and subsequently completed Internal Medicine residency and Infectious Diseases fellowship from Baylor College of Medicine, Houston, TX. She received a Masters of Science in Clinical Investigation from the Graduate School of Biomedical Sciences, Baylor College of Medicine, Houston, TX. Dr Aslam's current NIH-funded research is in the area of hemodialysis catheter-related infections with a focus on biofilms.
11:45-12:15
SPECIAL LECTURE
Translating Mechanisms to Management Award
TBA
12:15-12:30
Top Abstract Awards
12:30-2:00
Lunch Symposia Hosted by Conference (RSVP Required)
Selection made during registration
Lunch Symposia
12:30-2:00
12:30-2:00
Lunch Symposium T1
Precision Medicine for All: Challenges and Opportunities for Critical Illness
CME Available
Precision medicine aims to lead to personalized treatment and improved outcomes. However its application in AKI and critical care faces many challenges including patient characterization and specific targets for timely interventions. This session will discuss approaches to address these challenges and provide a framework for achieving personalized care.
Moderators: Joy and Murray
Can We be Precise for Critical Care? - Kellum
Endophenotypes in AKI: Path to Precision Interventions? - Parikh
Should We Focus on Personalized Medicine Rather than Precision? - Vincent

Melanie Joy, PharmD, PhD

Dr. Joy is an accomplished translational researcher having spent the last 24+ years as a researcher and clinician in nephrology, pharmacology, and pharmaceutics. Dr. Joy spent the last ~6 years at the University of Colorado and is now a tenured Associate Professor in the Skaggs School of Pharmacy and Pharmaceutical Sciences, with a joint appointment in the School of Medicine Division of Nephrology. Previously, Dr. Joy spent 16 years at the University of North Carolina (UNC) where she was an Associate Professor of Medicine (Nephrology) and Pharmacy. Dr. Joy has consulted with numerous pharmaceutical companies on study design and has served on pharmaceutical advisory boards. Dr. Joy has conducted over 60 studies (NIH, foundation, and pharmaceutical company funded) investigating new drugs and devices in the kidney disease population and was Director of the UNC Nephrology Clinical Trials program from 1998 to 2003. She has subsequently focused on her investigator initiated and NIH funded research. Her lab is currently funded by two NIH R01 grants. Dr. Joy has published 86 articles, 21 book chapters, and over 90 abstracts. Dr. Joy is experienced in the conduct of renal pharmacology studies related to acute and chronic kidney diseases. Dr. Joy has led and managed a chronic kidney disease clinic that focused on the treatments of kidney disease complications including phosphorus management and anemia. Professional activities have included US FDA Cardiovascular and Renal Drugs Advisory Committee Member, USP Nephrology and Urology Expert Committee member, NIH NIDDK Ad Hoc reviewer for numerous study sections, several American Society of Nephrology committees and initiatives, a Kidney Health Initiative (KHI) stakeholder, American College of Clinical Pharmacy (ACCP) Leadership Institute, and UNC Mid-Career Leadership Initiative. Dr. Joy has extensive connections to clinicians, researchers, industry, and professional organizations in the nephrology area.

John Kellum, MD

John A. Kellum, MD, FACP, MCCM John A. Kellum, MD, MCCM is Professor of Critical Care Medicine, Medicine, Bioengineering and Clinical and Translational Science, and Vice Chair for Research within the Department of Critical Care Medicine and Director of the Center for Critical Care Nephrology at the University of Pittsburgh. Dr. Kellum received his medical degree from the Medical College of Ohio in 1984. His postgraduate training includes an internship and residency in Internal Medicine at the University of Rochester, NY, and a Fellowship in Critical Care Medicine at the University of Pittsburgh Medical Center. Dr. Kellum is actively involved in education, research and administration. Dr. Kellum’s research interests span various aspects of Critical Care Medicine, but center in critical care nephrology, sepsis and multi-organ failure, and clinical epidemiology, including consensus development and research methodology. He has authored more than 250 publications and has won several awards for teaching. He lectures widely and has given more than 300 seminars and invited lectures worldwide related to his research.

Patrick Murray, Prof

Patrick Murray is Professor of Clinical Pharmacology in University College Dublin, and a consultant physician (clinical pharmacologist & nephrologist) at the Mater Misericordiae University Hospital, Dublin, Ireland. He received his medical education at University College Dublin, Ireland. Following his internship at the Mater Misericordiae University Hospital in Dublin, he completed a residency in internal medicine at Hennepin County Medical Center in Minneapolis, Minnesota, USA. He completed fellowship training programs in nephrology, critical care medicine, and clinical pharmacology at the University Of Chicago Hospitals in Chicago, Illinois, USA. He is board-certified in nephrology, critical care medicine, and clinical pharmacology. He practiced as an intensivist, nephrologist, and clinical pharmacologist at the University of Chicago Hospitals from 1996–2008, serving as the fellowship training program director in nephrology, also directing the Acute Dialysis Service. He has a longstanding interest in research and education to improve the prevention, diagnosis, and therapy of acute kidney injury and nephrotoxicity, and the pharmacotherapy of patients with kidney disease. He is a member of several international consensus groups that have produced guidelines for research and practice in the field of acute kidney injury (ADQI, AKIN, KDOQI). Since 2008, he has been the Professor of Clinical Pharmacology at University College Dublin, and a Consultant in Nephrology & Clinical Pharmacology at the Mater Misericordiae University Hospital. He is Chair of the Mater Misericordiae University Hospital Drugs & Therapeutics Committee. He is the Clinical Director of the UCD-Mater Clinical Research Centre. In 2011, he was appointed Associate Dean for International Affairs in the UCD School of Medicine and Medical Science. In 2012, he was appointed Director of the Dublin Centre for Clinical Research (DCCR) Consortium Network, and also Clinical Director of the Irish Clinical Research Infrastructure Network (ICRIN). Since December 2012, he has been the Dean and Head of the School of Medicine at UCD.

Chirag Parikh, MD, PhD

Chirag R. Parikh, MD, PhD, FACP, FASN, is an Associate Professor of Medicine in the Section of Nephrology, Associate Professor of Investigative Medicine, and Director, Program of Applied Translational Research, at Yale University School of Medicine. He is also an Associate Professor in the Clinical Epidemiology Research Center at the VA Connecticut Health Care System. His principal research interests focus on the translation and validation of novel biomarkers for the diagnosis and prognosis of acute kidney injury. Dr. Parikh completed the largest validation study of urinary biomarkers in which more than 10,000 samples were collected for the measurement of biomarkers for early diagnosis and prognosis of AKI after cardiac surgery. In 2005, he founded TRIBE-AKI (Translational Research Investigating Biomarker Endpoints in AKI)—a consortium of researchers across several states which have enrolled over 2500 patients in three cohort studies. TRIBE-AKI has yielded groundbreaking, nationally recognized achievements in biomarker discovery and validation, and its success led to establishment of the Program of Applied Translational Research in 2012. The program is comprised of a multidisciplinary team of talented physicians and scientists committed to patient-oriented research and improved outcomes in clinical medicine and disease management. As Director of PATR, Dr. Parikh oversees several NIH-sponsored, multicenter studies testing biomarkers in the areas of cardiac surgery, kidney transplantation, aging, HIV, and hepatorenal syndrome.

John Louis Vincent, MD PhD

Professor Vincent is Professor of intensive care medicine at the University of Brussels (Université Libre de Bruxelles) and intensivist in the Department of Intensive Care at Erasme University Hospital in Brussels. He obtained his PhD degree at the University of Brussels in 1982. He is a Past-President of the World Federation of Societies of Intensive and Critical Care Medicine (WFSICCM), the European Society of Intensive Care Medicine (ESICM), the European Shock Society (ESS), the Belgian Society of Intensive Care Medicine (SIZ), and the International Sepsis Forum (ISF). He was a Council member of the Society of Critical Care Medicine (SCCM) from 2011-2013. He is member of the Belgian Royal Academy of Medicine. Dr. Vincent has signed more than 900 original articles, some 400 book chapters and review articles, 1000 original abstracts, and has edited 102 books. He is co-editor of the “Textbook of Critical Care†(Elsevier Saunders) and the “Encyclopedia of Intensive Care Medicine†(Springer). He is the editor-in-chief of Critical Care, Current Opinion in Critical Care, and ICU Management & Practice and member of the editorial boards of about 30 other journals, including Critical Care Medicine (senior editor), the American Journal of Respiratory and Critical Care Medicine (AJRCCM), PLoS Medicine, Lancet Infectious Diseases, Intensive Care Medicine, Shock, the Journal of Critical Care and Annals of Intensive Care. Dr Vincent has received several awards including the College Medalist Award of the American College of Chest Physicians, the Society Medal (lifetime award) of the European Society of Intensive Care Medicine,), the distinguished investigator Award and the Lifetime Achievement Award of the Society of Critical Care Medicine, and the prestigious Belgian scientific award of the FRS-FNRS (Prix Scientifique Joseph Maisin-Sciences biomédicales cliniques). His name appears more than 1000 times in Pubmed, and his work has been cited more than 140,000 times; his H-index is 156. In recognition for these achievements, he was awarded the title of Baron by King Albert II of Belgium in 2013.
12:30-2:00
Lunch Symposium T2
Hydration and Kidney Health
CME Available
Fluid administration is the commonest approach to manage patients with perceived renal dysfunction. However is this the correct approach for all patients? This symposium will review the evidence for our current strategy and provide guidance on best practices to manage patients with fluids to improve kidney function.
Moderators: Wu and Chakaravarthi
Fluid Therapy for AKI: When, How and What? - Qian
AKI and Exercise: The Good, the Bad and the Ugly - Burdmann
Vasopressin and Kidney Injury - Madero

Emmanuel Burdmann, MD, PhD

Dr. Emmanuel A. Burdmann attended medical school at the University of São Paulo Medical School, São Paulo, Brazil and completed residency in Internal Medicine and fellowships in Nephrology at Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil. He received his Doctorate in Nephrology from the University of São Paulo Medical School and did a post-doc research fellowship at the Nephrology Division of the Oregon Health Sciences University, Portland, Oregon. Dr. Burdmann is the past-president of the Latin-American Society of Nephrology and Hypertension and is currently the president of the Brazilian Society of Nephrology. His current academic position is as Associate Professor of Nephrology at the São José do Rio Preto Medical School, where he is responsible for the care of the AKI patients and for the Post-Graduation Program. Dr Burdmann serves as Associate-Editor in the Clinical Journal of the American Society of Nephrology and in Nephrology, Dialysis, and Transplantation. He is member of AKIN and KDIGO. His research interests centers on acute kidney injury and drugs and animal venoms nephrotoxicity.

Rajasekara Chakravarthi, MD, DNB (Nephrology)

Dr. Rajasekara Chakravarthi graduated from Mysore University (MBBS) in 1993 and completed MD (internal medicine) from the same university in 1996. Subsequently he trained as a fellow in Nephrology under the guidance of Dr.M.K.Mani between June 1997 to June 1999. He successfully completed the national board of examinations (Nephrology) DNB-NBE India. He worked as a Consultant Nephrologist at JSS medical college and hospitals Mysore between Aug 1999 to Oct 2000 and then as a Consultant Nephrologist at Apollo hospitals Chennai between Oct 2000 to March 2002. He shifted to the city of Hyderabad in March 2002 and started the department of Nephrology at CARE hospitals, the institute of medical sciences. He was the Head of the department of Nephrology CARE hospitals Banjara hills from March 2002 to September 2011. Since September 2011 till Sep 2015 he officiated as the Director Nephrology services CARE group of hospitals India which is a 16 hospitals group spread across the country. Since Sep 2015 till date he is the director of Nephrology services STAR hospitals, Hyderabad. India. He has keen interest in understanding Acute Kidney Injury and is a member of the AKIN and ADQI (2011, Dublin) (2016, Asiago). He is appointed as faculty of the KDIGO working group on AKI - 2019. He has more than 75 publications in various national and international journals and more than 160 presentations in various conferences. He was a visiting and adjunct faculty to National Institute of Nutrition Hyderabad and JSS University Mysore. He is an organizing committee member and invited faculty for the international CRRT conference held at San Diego yearly since 2005 till date. He is a reviewer for the Indian Journal of nephrology, the official journal of the Indian society of Nephrology, Indian Heart Journal, Journal of Indian College of cardiology, Indian journal of Transplantation and Nephrology and Indian journal of Hypertension. He is presently nominated as a member AKI-committee of the International society of Nephrology. In the year 2016 he has organized and co-chaired the 17th ADQI held at Hyderabad India on Management of AKI in the developing world. He has been organizing AKI and CRRT conferences and works shops since 2004 . He has been part of the active transplantation programme since 1997 at Apollo Hospitals - Chennai, JSS Medical College Hospital - Mysore, Care Group of Hospitals - India and presently at STAR Hospitals - Hyderabad, being part of more than 650 transplantations so far both live related and cadaveric. He is the founding trustee of the NGO, Care For Your Kidney Foundation (cfykf) started in the year 2015 with the aim of creating awareness in the public regarding kidney disease and preventing kidney disease in the community. So far the foundation has completed more than five thousand screening in the urban slums of Hyderabad. The foundation also subsidizes dialysis and kidney transplants for the needy population of the country. He is the founding director of Renown clinical services which is a group offering Nephrology services presently to six hospitals in the city of Hyderabad. An Annual meeting on AKI (acute kidney injury) and CRRT is conducted by Renown associates since 2016 namely Selections from Sandiego. This meeting provides training in all modalities of RRT (dialysis) in ICU and brings the highlights of the AKI and CRRT meeting held annually in Sandiego by CRRT Inc. and UCSD. This meeting held at Sandiego annually is into its 25th year.

Magdalena Madero, MD

Magdalena Madero, MD, is the Chief of Nephrology at the Instituto Nacional de Cardiología in Mexico City. She was trained in Internal Medicine at St Elisabeth’s Medical Center in Boston, MA, and then underwent her nephrology training at Tufts Medical Center also in Boston, MA. She went back to Mexico City in 2007 where she joined the nephrology staff at Instituto Nacional de Cardilogía and became the Head of the Nephrology Division in 2011. Dr. Madero's research interests include CKD complications and outcomes in addition to the metabolic and renal effects of fructose and uric acid and more recently is interested in CKD of unknown origin. As part of her educational activities she runs one of the largest renal fellowship programs in the country (affiliated to the main National Mexican University [UNAM]) in addition to teaching the nephrology course at the undergraduate Panamerican University medical school. She is the past president of Mexican Institute of Renal Research (IMIN) and currently acts as the International Editor for the American Journal of Kidney Diseases. She has recently joined the KDIGO Executive Committee.

Qi Qian, MD

Dr. Qi Qian is a faculty nephrologist and Professor of Medicine and Professor of Physiology at the Mayo Clinic College of Medicine and Mayo Graduate School, USA. She is the Director of the Mayo Clinic Rochester Nephrology Hospital Practice. She is also an adjunct Professor of Medicine at four top universities in China (Nanjing University School of Medicine in Nanjing, Fourth Military Medical University in Xi’an, Zhejiang University in Hangzhou, and Fudan University, Shanghai, China) A graduate of the Shanghai 2nd Medical University, Dr. Qian received her post-graduate training in medicine and nephrology at the Albert Einstein College of Medicine, Bronx, New York and was recruited to join the staff at Mayo Clinic upon her graduation from fellowship training in 1999. Dr. Qian's professional focus is on patient care, clinical/translational research and education in the area of renal tubular disorders. In the years of 2000-2008, she conducted basic science research on the renal/vascular pathophysiology through funding from Mayo Clinic Foundation and the National Institutes of Health (NIH-NIDDK). Her expertise in renal and vascular physiology and pathophysiology adds an important dimension to her management of patients with renal tubular diseases. Dr. Qian also heads the Mayo Clinic Acid-Base Electrolyte Interest Group. She is the principal investigator on a number of studies investigating the effects of electrolyte alterations and renal tubular function. Dr. Qian is an award-winning educator at Mayo Clinic. She has mentored a large number of trainees and is an author and content expert for “AskMayoExpertâ€, a popular Mayo Clinic web-based medical practice reference for clinicians all over the United States. She currently serves as the president of the Chinese American Society of Nephrology and an ISN Educational Ambassador.

Vincent Wu, MD, PhD

Vin-Cent actively involved in the analysis of a database of acute kidney injury in the National Taiwan University Study Group on Acute Renal Failure (NSARF) and Consortium for Acute Kidney Injury and Renal Diseases (CAKs) strive to advance high-quality care in acute kidney injury (AKI) and aspires to plunge the worldwide increasing prevalence of chronic kidney disease (CKD) from the perspective of AKI-CKD transition.
12:30-2:00
Lunch Symposium T3
Imaging Techniques in Critically Ill Patients with Kidney Disease
CME Available
Patients with kidney dysfunction evoke concern whenever an imaging study is needed. This session will deliberate some of the common issues for evaluating patients with different imaging techniques.
Moderators: Nadim and Sirsawat
Should We Avoid Radiocontrast Enhanced Imaging? - Rosner
What is the Role of MRI? - Selby
Imaging Considerations in High Risk Oncology Patients? - Ng

Mitra Nadim, MD, FASN

Mitra Nadim is an Associate Professor of Clinical Medicine in the Division of Nephrology and Hypertension at the University of Southern California. She completed her medical school at UCLA, Internal Medicine Residencey at the Beth Israel Hospital in Boston and Nephrology Fellowship at Brigham and Women’s / Massachusetts General Hospital joint program. She is the the renal system chair for the Year 2 Medical School curriculum at Keck School of Medicine and the Director of USC’s Hypertension Center.

Chaan Ng, MD

Mitchell Rosner, MD

Dr. Rosner is currently the Henry B. Mulholland Professor of Medicine at the University of Virginia School of Medicine as well as the Chairman of the Department of Medicine. Dr. Rosner serves on the executive committee of training program directors for the American Society of Nephrology. His research interests include: sodium and water metabolism and acute kidney injury. He is a fellow of the American Society of Nephrology and a fellow of the American College of Physicians

Nick Selby, MD

Dr Selby studied medicine at the University of Nottingham, graduating in 1998, and after completing post-graduate training in the East Midlands was appointed a full-time NHS consultant nephrologist at the Royal Derby Hospital in 2009. In 2015 he was appointed Associate Professor of Nephrology at the University of Nottingham, based in the Centre for Kidney Research and Innovation (www.nottingham.ac.uk/research/groups/renal), Royal Derby Hospital Postgraduate Medical School. Dr. Selby is a clinical academic with primary interests in Acute Kidney Injury (AKI), Magnetic Resonance Imaging (MRI) of the kidney and the haemodynamic consequences of dialysis. He led the development of one of the first e-alert systems for AKI in the UK and is CI on several investigator-instigated studies in these areas. Since 2011 Dr Selby has been awarded peer reviewed grant funding from MRC, the Health Foundation, Kidney Research UK and British Renal Society. He has published over 60 peer-reviewed articles. Dr Selby has several national AKI roles, including leadership of the AKI Clinical Study Group that sits within the UK Kidney Research Consortium, the co-chair of the UK Renal Imaging Network and programme board of the NHS England ‘Think Kidneys’ programme.

Nattachai Srisawat, MD

Current position - Director of Excellence Center for Critical Care Nephrology, King Chulalongkorn Memorial Hospital, Thai Red Cross, Bangkok, Thailand - Division of Nephrology, Department of Medicine, Chulalongkorn University, Bangkok, Thailand - Collaborating CRISMA faculty member Department of Critical Care Medicine, University of Pittsburgh School of Medicine, USA My background: After finishing Nephrology training from Thailand in 2007, He became the part of CRISMA research fellow for 2 years and clinical fellow of Critical Care Medicine for 1 year under mentorship by Professor John A Kellum at Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pennsylvania, USA. He received European Diploma of Intensive Care Medicine in 2012. His main research focused in AKI epidemiology in resource limited setting, novel biomarkers of AKI, and tropical infections causing AKI such as leptospirosis, and dengue infection.
12:30-2:00
Lunch Symposium T4
Targeting Renal Recovery from Critical Illness
CME Available
Non-recovery from AKi is associated with a high mortality, cardiovascular disease and increased resource utilization. There is great need to target interventions to improve recovery from AKI. This symposium will discuss the key issues in this area.
Moderators: Basu and Cerda
How Should We Monitor for Renal Recovery? - Prowle
Do We Have Biomarkers that Predict Recovery? - Koyner
Caring for the AKI Survivor: What is Required? - Wald

Rajit Basu, MD MS FCCM

Dr. Basu is dedicated to improving the recognition, treatment, and outcomes of critically ill children suffering acute kidney injury. As Co-Director of the Center for Acute Care Nephrology at Cincinnati Children's Hospital, Dr. Basu oversees projects in the pediatric intensive care unit investigating AKI prediction by risk stratified optimization of biomarkers (renal angina), biomarker and fluid overload directed renal replacement therapy initiation, and use of the EMR to provide clinical decision support for management of AKI and fluid balance. Prior to arriving at Cincinnati Children's in 2009, Dr. Basu completed his Pediatric Critical Care fellowship and Pediatric residency at Northwestern University in Chicago. Originally from South Bend, Indiana, he is a graduate of Indiana University Medical School and the University of Notre Dame (undergraduate degree in Biochemistry).

Jorge Cerda, MD, MS, FACP, FASN

Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY Clinical Associate Professor of Medicine, Albany Medical College, Albany NY Fulbright Scholar, 1980 Fellow, American College of Physicians Fellow, American Society of Nephrology Organizing Committee, International Conference AKI & CRRT AKI Advisory Group, American Society of Nephrology AKI Committee, and "0by25" Initiative, International Society of Nephrology Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease Associate Editor, Blood Purification and Kidney International Reports Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world

Jay Koyner, MD

Dr. Koyner is an Associate Professor of Medicine in the Section of Nephrology at the University of Chicago. He completed his Internal Medicine and Nephrology training at the University of Chicago Medical Center where he currently serves as the medical director of the Inpatient Dialysis Unit and Director of ICU Nephrology. His critical care nephrology research interests have focused on the utilization of plasma and urine biomarkers to improve patient risk stratification and outcomes in the setting of AKI. In addition to biomarkers, other research interests include predictive analytics, AKI following cardiac surgery, CRRT and AKI therapeutics. He has published over 80 peer-reviewed articles and book chapters on AKI and the care of patients in with kidney injury in the ICU.

John Prowle, MA MSc MD FRCP FFICM

Dr Prowle is a Senior Clinical Lecturer in Intensive Care Medicine within the Critical Care and Perioperative Medicine Research Group at Barts and the London School of Medicine and Dentistry, Queen Mary University of London and is an Honorary Consultant Physician in Intensive Care Medicine and Nephrology at the Royal London Hospital, Barts Health NHS Trust, London, UK. He graduated in medicine from the University of Cambridge in 1999 and undertook Doctoral Research under the supervision of Prof Rinaldo Bellomo in Melbourne, Australia leading to the award of his research doctorate in 2013. Dr Prowle’s academic interests include the Pathogenesis, Diagnosis and Treatment and Outcomes of Acute Kidney Injury, Continuous Renal Replacement Therapies in the ICU, Fluid Therapy and Medical Complications of Major Surgery. Since 2009 he has co-authored over 80 peer-reviewed publications and book chapters, including chapters related to Acute Kidney Injury in the latest editions of the Oxford Textbook of Clinical Nephrology and the Oxford Textbook of Critical Care.

Ron Wald, MD

Ron Wald is a nephrologist at St. Michael's Hospital in Toronto and an Associate Professor of Medicine at the University of Toronto. His primary research interest is in critical care nephrology and he has been involved in several clinical trials in this area. He is currently co-leading an international randomized controlled trial on the timing of renal replacement therapy in acute kidney injury. Ron also has an interest in the care provided to patients who survive an episode of acute kidney injury and has conducted research using large administrative datasets to study this population. He is co-leading a clinical trial comparing post-discharge follow-up with a nephrologist vs usual care after an episode of severe acute kidney injury.
12:30-2:00
Lunch Symposium I2
Additional Industry Session Offered (Non-CME)
Details


SESSION III: EMERGING CONCEPTS IN AKI AND RRT

Plenary 4 MINI SYMPOSIA
Novel Strategies in AKI Management
2:00-3:45

Andrew Lewington, MD

Dr Andrew Lewington studied medicine as an undergraduate in London before pursuing a career in renal medicine. He studied in Leicester UK and Washington University USA where he worked in Mark Hammermann's laboratory investigating the molecular mechanisms underlying ischaemic acute kidney injury.Dr Lewington was appointed consultant renal physician/honorary senior lecturer at Leeds Teaching Hospitals in 2004. He works as an NHS clinician providing a specialist renal opinion on acutely ill patients on the ICU across Leeds. He was an expert adviser on the UK NCEPOD adding insult to injury AKI study, working from his position on the Renal Association executive committee to improve the care that patients who develop AKI receive. He is the lead author of the 5th Renal Association AKI clinical practice guidelines. During his time in Leeds he has developed collaborative research with an internationally recognised proteomics group. He currently has a nephrology fellow investigating potential proteomic biomarkers of kidney dysfunction in the early phase following kidney transplantation. He is Clinical Sub Dean for the Leeds Teaching Hospitals and is heavily involved in the delivery of undergraduate medical education at the University of Leeds.

Ron Wald, MD

Ron Wald is a nephrologist at St. Michael's Hospital in Toronto and an Associate Professor of Medicine at the University of Toronto. His primary research interest is in critical care nephrology and he has been involved in several clinical trials in this area. He is currently co-leading an international randomized controlled trial on the timing of renal replacement therapy in acute kidney injury. Ron also has an interest in the care provided to patients who survive an episode of acute kidney injury and has conducted research using large administrative datasets to study this population. He is co-leading a clinical trial comparing post-discharge follow-up with a nephrologist vs usual care after an episode of severe acute kidney injury.
2:00-2:15
Cardiorenal Syndrome: What Have We Learned?
Room: Coronado Ballroom

Peter McCullough, MD, MPH

Dr. McCullough is an internationally recognized leader in academic cardiology with over 800 published, scientific communications. He is the co-editor of Reviews in Cardiovascular Medicine and serves on the editorial boards of multiple specialty journals. Dr. McCullough has led and participated on multiple consensus and guidelines panels in the fields of cardiology, nephrology, and critical care medicine.
2:15-2:30
Vitamin D Regulation in AKI: Opportunity to Intervene?

Marlies Ostermann, MD

Dr Ostermann is a Consultant in Critical Care & Nephrology at Guy’s & St Thomas’ Foundation Trust, London and Honorary Senior Lecturer at King’s College London. After medical school in Goettingen (Germany), she did her postgraduate training in London and Canada. She holds a PhD degree from the University of Goettingen, an MD degree from the University of London and a postgraduate Diploma in Medical Education. She is an active member of the European Society of Intensive Care Society, Renal Association and Intensive Care Society UK, and a Fellow of the Faculty of Intensive Care Medicine. She is also a co-founder of the London AKI Network. Her research interests include acute kidney injury in critically ill and all aspects of renal replacement therapy.
2:30-2:45
Why are Some People Resistant to AKI?

John Kellum, MD

John A. Kellum, MD, FACP, MCCM John A. Kellum, MD, MCCM is Professor of Critical Care Medicine, Medicine, Bioengineering and Clinical and Translational Science, and Vice Chair for Research within the Department of Critical Care Medicine and Director of the Center for Critical Care Nephrology at the University of Pittsburgh. Dr. Kellum received his medical degree from the Medical College of Ohio in 1984. His postgraduate training includes an internship and residency in Internal Medicine at the University of Rochester, NY, and a Fellowship in Critical Care Medicine at the University of Pittsburgh Medical Center. Dr. Kellum is actively involved in education, research and administration. Dr. Kellum’s research interests span various aspects of Critical Care Medicine, but center in critical care nephrology, sepsis and multi-organ failure, and clinical epidemiology, including consensus development and research methodology. He has authored more than 250 publications and has won several awards for teaching. He lectures widely and has given more than 300 seminars and invited lectures worldwide related to his research.
2:45-3:00
Does AKI Always Lead to CKD and Premature Death?

Chirag Parikh, MD, PhD

Chirag R. Parikh, MD, PhD, FACP, FASN, is an Associate Professor of Medicine in the Section of Nephrology, Associate Professor of Investigative Medicine, and Director, Program of Applied Translational Research, at Yale University School of Medicine. He is also an Associate Professor in the Clinical Epidemiology Research Center at the VA Connecticut Health Care System. His principal research interests focus on the translation and validation of novel biomarkers for the diagnosis and prognosis of acute kidney injury. Dr. Parikh completed the largest validation study of urinary biomarkers in which more than 10,000 samples were collected for the measurement of biomarkers for early diagnosis and prognosis of AKI after cardiac surgery. In 2005, he founded TRIBE-AKI (Translational Research Investigating Biomarker Endpoints in AKI)—a consortium of researchers across several states which have enrolled over 2500 patients in three cohort studies. TRIBE-AKI has yielded groundbreaking, nationally recognized achievements in biomarker discovery and validation, and its success led to establishment of the Program of Applied Translational Research in 2012. The program is comprised of a multidisciplinary team of talented physicians and scientists committed to patient-oriented research and improved outcomes in clinical medicine and disease management. As Director of PATR, Dr. Parikh oversees several NIH-sponsored, multicenter studies testing biomarkers in the areas of cardiac surgery, kidney transplantation, aging, HIV, and hepatorenal syndrome.
3:00-3:15
Renal Functional Reserve: A Target for Intervention?

Claudio Ronco, MD

Actual Position:
Dr. Claudio Ronco
Director
Department of Nephrology
St. Bortolo Hospital
Viale Rodolfi 16
I-36100 Vicenza
Italy

Name: Claudio Ronco

Date of birth: July 12, 1951

Education: High School Diploma at Vicenza Classic Lyceum “A.Pigafetta” in 1970 with the score: 45/60. Dr. Ronco Graduated in Medicine at University of Padua in 1976 with the score 110/110 and merit debating an experimental thesis on title “ Aspects of the Nitrogen metabolism in the nephrotic syndrome”.
From 1973 to 1976 has been intern at Institute of Clinical Internal Medicine I^ of the University of Padua, directed by Prof. E. Fiaschi, in the Nephrology Department II, under the supervision of the Prof. G. Maschio.

Postgraduate training: From July 1976 to November 1977 he has been internal resident at the Division of Internal Medicine of the St. Bortolo Hospital in Vicenza, directed by Prof. D. Corà.
In 1979 he has achieved the Specialization Diploma on Medical Nephrology at The postgraduate school of internal medicine of the University of Padua, with the score 70/70 debating a thesis on the “new methodologies for the measurement of the urinary bicarbonate”
In 1989 he has achieved the Diploma of Specialization in Pediatric Nephrology at University of Naples.
1982: Visiting Fellow at the Mount Sinai Hospital in New York, Department of Internal medicine, Nephrology Division, for four months. He carried out studies on hemofiltration and glomerular filtration with J.P. Bosh, S. Glabman and M. Levitt.
1984: Visiting Physician at the Mount Sinai Hospital In New York for two weeks and at VA Hospital in Los Angeles for two weeks.
1985: Visiting professor at the Nephrology Division of the George Washington University Hospital, Washington DC, and NIH at National Naval Medical Center of Bethesda for three months.
1988: Visiting professor at the Renal and Hypertension Division of George Washington University for three months.
1991: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
1995: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.

Teaching acitivity and Academic Qualifications: From 1978 to 1984 he has been in charge of the teaching program of Nephrology and Dialysis at Professional Nursing School in Vicenza.
During the academic years 1989-01 he has been in charge of teaching “Dialytic therapy” at Specialization School in Medical Nephrology of Padua University where he holds a post of Professor of Nephrology in charge of the teaching program concerning Hemodialysis and renal replacement therapies in critically ill patients.
October 1999-December 2000: Professor of Medicine at Albert Einstein College of Medicine and Director of the Renal laboratory at the Beth israel Medical Center in New York.
In the last ten years Professor Ronco was asked to deliver lectures and seminars in several Universities.
He has delivered in meetings and seminars more than 300 lectures and presentations.

In 1982 he introduced in Italy the use of continuous hemofiltration and in 1986 he published the first series of neonates treated with arteriovenous hemofiltration.
In 1985 He contributed to the introduction in Europe of high flux dialysis and derived therapies. He also established the dangerous effect of backfiltration in a contaminated dialysis fluid condition.
He has conducted a series of clinical and experimental researches in the following fields:
- Kinetics of fluid and solute removal in peritoneal dialysis and hemodialysis
- Treatment of Acute renal failure with intermittent and continuous therapies
- Renal replacement therapy in the neonate
- Development of new treatment modalities for acute and chronic renal failure.
- Studies on biomaterials
- Studies on glomerular filtration in humans and renal functional reserve
- Renal physiology in pregnancy
- Hydraulics and flow dynamics in the extracorporeal circulation
- Adequacy of dialysis
- Acid-Base Balance in uremia and dialysis
- Acute renal failure and Critical Care Nephrology

Professional employement and Hospital appointments:
Assistant of clinical nephrology from 1977 to 1984 at Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Associate of clinical nephrology from 1984 at Department of Nephrology , St. Bortolo Hospital, Vicenza, Italy.
From 1984 he is director of the hemodialysis and peritoneal dialysis center of the Department of Nephrology at St. Bortolo Hospital, Vicenza, Italy.
From October 25, 1999 to December 1st 2000 Dr. Ronco has been Director of the research laboratory of Hemodialysis at the Beth Israel Medical center of New York and Visiting Professor of Medicine at the Albert Einstein College of Medicine of new York
Today Dr. Ronco is director of the Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.

Board certification: In 1989 he has achieved in Rome, the National License for Nephrology Chair and Directional Functions, with the score 94/100.

Professional Society Membership: He is mamber of the council of several scientific societies and he is editor in chief of the international journal of artificial organs and contributions to nephrology.

Awards and honors:
1983 Schwartz Award, for the best paper of the year at St. Bortolo Hospital.
1984 G.F. Volpato Grant for the best research project on acute renal failure in Italy
1989 Best paper Prize at the Italian Society of nephrology meeting.
1991 ESAO RESEARCH AWARD for the best paper presented at the European Society for Artificial Organs.
1996 Arturo Borsatti Award of Padova University as a best nephrologist of the year.
2004 Lifetime achievement award

Other professional activities: He has organized several congresses and meetings in the area of nephrology and Intensive care from 1982 to today.
He is member of several advisory groups for clinical trials and dialysis research.

Lectures and publications: Dr. Ronco has coauthored 560 papers, 36 book chapters, 26 books, 7 monographic journal issues and has delivered more than 300 lectures in international meetings and universities. His personal impact factor calculated at december 2002 is 391.
3:15-3:30
Clinical Prediction Rules: Can We Improve?

Lui Forni, MD

3:30-3:45
Subphenotypes for AKI: Where are We Headed?

Ravindra Mehta, MBBS, MD, DM, FACP

Dr. Mehta is Professor of Medicine in the Division of Nephrology and Associate Chair for Clinical Affairs in the Department of Medicine at the University of California, San Diego (UCSD) where he directs the Clinical nephrology and dialysis programs. He is also the Chair of the International Society of Nephrology Commission on Acute Renal Failure, founding member of the Acute Dialysis Quality Initiative. He received the M.B.B.S. degree (1976) from the Government Medical School in Amritsar, India, and the M.D. (1979) and D.M. (1981) degrees from the Post Graduate Institute of Medical Education and Research in Chandigarh, India. He subsequently completed a nephrology fellowship at the University of Rochester in Rochester New York and obtained his boards in internal medicine (1986) and Nephrology (1988). He has been on the faculty at San Diego since 1988. His reserach interests are in the field of acute renal failure and he has directed several clinical studies in the management of patients with ARF including comparing different dialytic modalities, conducting large multicenter observational studies of ARF with the PICARD group, evaluating different predictive models for outcomes in ARF, investigating the role of cytokine removal by dialysis membranes in sepsis and ARF, and evaluating techniques for determining the amount of excess fluid in dialysis patients.
3:45-4:15
Coffee Break
Plenary 5 MINI SYMPOSIA
Challenges and Controversies in Renal Support and CRRT
4:15-6:00

David Selewski, MD

I am an Assistant Professor in the Department of Pediatrics within the Division of Nephrology at the University of Michigan. I received my training in pediatrics and pediatric nephrology at the University of Michigan. My clinical and research interests include pediatric critical care nephrology including pediatric & neonatal acute kidney injury, fluid overload, and continuous renal replacement therapy.

Ashita Tolwani, MD

Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
4:15-4:30
Volume First in the Management of Patients with AKI Receiving RRT?
Room: Coronado Ballroom

Ron Wald, MD

Ron Wald is a nephrologist at St. Michael's Hospital in Toronto and an Associate Professor of Medicine at the University of Toronto. His primary research interest is in critical care nephrology and he has been involved in several clinical trials in this area. He is currently co-leading an international randomized controlled trial on the timing of renal replacement therapy in acute kidney injury. Ron also has an interest in the care provided to patients who survive an episode of acute kidney injury and has conducted research using large administrative datasets to study this population. He is co-leading a clinical trial comparing post-discharge follow-up with a nephrologist vs usual care after an episode of severe acute kidney injury.
4:30-4:45
Calcium Containing Solutions for Citrate CRRT: Does it Work?

Ravindra Mehta, MBBS, MD, DM, FACP

Dr. Mehta is Professor of Medicine in the Division of Nephrology and Associate Chair for Clinical Affairs in the Department of Medicine at the University of California, San Diego (UCSD) where he directs the Clinical nephrology and dialysis programs. He is also the Chair of the International Society of Nephrology Commission on Acute Renal Failure, founding member of the Acute Dialysis Quality Initiative. He received the M.B.B.S. degree (1976) from the Government Medical School in Amritsar, India, and the M.D. (1979) and D.M. (1981) degrees from the Post Graduate Institute of Medical Education and Research in Chandigarh, India. He subsequently completed a nephrology fellowship at the University of Rochester in Rochester New York and obtained his boards in internal medicine (1986) and Nephrology (1988). He has been on the faculty at San Diego since 1988. His reserach interests are in the field of acute renal failure and he has directed several clinical studies in the management of patients with ARF including comparing different dialytic modalities, conducting large multicenter observational studies of ARF with the PICARD group, evaluating different predictive models for outcomes in ARF, investigating the role of cytokine removal by dialysis membranes in sepsis and ARF, and evaluating techniques for determining the amount of excess fluid in dialysis patients.
4:45-5:00
Antibiotic Dosing in Patients on RRT: Are We Doing it Right?

Linda Awdishu, PharmD, MAS

Linda Awdishu earned her Bachelors of Science in Pharmacy from the University of Toronto in 1999, Doctor of Pharmacy from the University of Colorado in 2008 and Masters of Clinical Research from the University of California in 2007. She is an Associate Clinical Professor of Pharmacy and Medicine at UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences. She maintains a clinical practice in the chronic kidney disease program. Her research program is focused on drug induced kidney injury.
5:00-5:30
SPECIAL LECTURE
Quality of Care for AKI: Highlights from ADQI 22

Kianoush Kashani, MD

Kianoush Kashani, MD is a consultant in the Division of Nephrology and Hypertension, Division of Pulmonary and Critical Care at Mayo Clinic, Rochester. His academic rank is Professor in Internal Medicine and Assistant Professor in Medical Education. His research interest is acute kidney injury, electrolyte disorders, simulation medicine, and critical care point-of-care ultrasonography.

Mitchell Rosner, MD

Dr. Rosner is currently the Henry B. Mulholland Professor of Medicine at the University of Virginia School of Medicine as well as the Chairman of the Department of Medicine. Dr. Rosner serves on the executive committee of training program directors for the American Society of Nephrology. His research interests include: sodium and water metabolism and acute kidney injury. He is a fellow of the American Society of Nephrology and a fellow of the American College of Physicians
5:30-6:00
VIEWPOINTS
Biomarker Based Management of AKI: Are We Ready
Moderator - Ronco
No We Don't Have Enough Data - LeGrand
We are Not Sure - Parikh
Yes Absolutely - Zarbock

Matthieu LeGrand, Pr

Pr Matthieu Legrand is Professor of Anesthesiology and Critical care medicine. He holds a PhD in physiology. He Works in the Department of anesthesiology, Critical care and burn unit of St-Louis hospital, university Paris Diderot, France. He has carried preclinical and clinical research in the field of critical care medicine with a special interest in critical care nephrology, sepsis and in burn critical care. He has served as a reviewer for several peer-review journals and expert in the field of critical care for several commitees and task forces.

Chirag Parikh, MD, PhD

Chirag R. Parikh, MD, PhD, FACP, FASN, is an Associate Professor of Medicine in the Section of Nephrology, Associate Professor of Investigative Medicine, and Director, Program of Applied Translational Research, at Yale University School of Medicine. He is also an Associate Professor in the Clinical Epidemiology Research Center at the VA Connecticut Health Care System. His principal research interests focus on the translation and validation of novel biomarkers for the diagnosis and prognosis of acute kidney injury. Dr. Parikh completed the largest validation study of urinary biomarkers in which more than 10,000 samples were collected for the measurement of biomarkers for early diagnosis and prognosis of AKI after cardiac surgery. In 2005, he founded TRIBE-AKI (Translational Research Investigating Biomarker Endpoints in AKI)—a consortium of researchers across several states which have enrolled over 2500 patients in three cohort studies. TRIBE-AKI has yielded groundbreaking, nationally recognized achievements in biomarker discovery and validation, and its success led to establishment of the Program of Applied Translational Research in 2012. The program is comprised of a multidisciplinary team of talented physicians and scientists committed to patient-oriented research and improved outcomes in clinical medicine and disease management. As Director of PATR, Dr. Parikh oversees several NIH-sponsored, multicenter studies testing biomarkers in the areas of cardiac surgery, kidney transplantation, aging, HIV, and hepatorenal syndrome.

Claudio Ronco, MD

Actual Position:
Dr. Claudio Ronco
Director
Department of Nephrology
St. Bortolo Hospital
Viale Rodolfi 16
I-36100 Vicenza
Italy

Name: Claudio Ronco

Date of birth: July 12, 1951

Education: High School Diploma at Vicenza Classic Lyceum “A.Pigafetta” in 1970 with the score: 45/60. Dr. Ronco Graduated in Medicine at University of Padua in 1976 with the score 110/110 and merit debating an experimental thesis on title “ Aspects of the Nitrogen metabolism in the nephrotic syndrome”.
From 1973 to 1976 has been intern at Institute of Clinical Internal Medicine I^ of the University of Padua, directed by Prof. E. Fiaschi, in the Nephrology Department II, under the supervision of the Prof. G. Maschio.

Postgraduate training: From July 1976 to November 1977 he has been internal resident at the Division of Internal Medicine of the St. Bortolo Hospital in Vicenza, directed by Prof. D. Corà.
In 1979 he has achieved the Specialization Diploma on Medical Nephrology at The postgraduate school of internal medicine of the University of Padua, with the score 70/70 debating a thesis on the “new methodologies for the measurement of the urinary bicarbonate”
In 1989 he has achieved the Diploma of Specialization in Pediatric Nephrology at University of Naples.
1982: Visiting Fellow at the Mount Sinai Hospital in New York, Department of Internal medicine, Nephrology Division, for four months. He carried out studies on hemofiltration and glomerular filtration with J.P. Bosh, S. Glabman and M. Levitt.
1984: Visiting Physician at the Mount Sinai Hospital In New York for two weeks and at VA Hospital in Los Angeles for two weeks.
1985: Visiting professor at the Nephrology Division of the George Washington University Hospital, Washington DC, and NIH at National Naval Medical Center of Bethesda for three months.
1988: Visiting professor at the Renal and Hypertension Division of George Washington University for three months.
1991: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
1995: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.

Teaching acitivity and Academic Qualifications: From 1978 to 1984 he has been in charge of the teaching program of Nephrology and Dialysis at Professional Nursing School in Vicenza.
During the academic years 1989-01 he has been in charge of teaching “Dialytic therapy” at Specialization School in Medical Nephrology of Padua University where he holds a post of Professor of Nephrology in charge of the teaching program concerning Hemodialysis and renal replacement therapies in critically ill patients.
October 1999-December 2000: Professor of Medicine at Albert Einstein College of Medicine and Director of the Renal laboratory at the Beth israel Medical Center in New York.
In the last ten years Professor Ronco was asked to deliver lectures and seminars in several Universities.
He has delivered in meetings and seminars more than 300 lectures and presentations.

In 1982 he introduced in Italy the use of continuous hemofiltration and in 1986 he published the first series of neonates treated with arteriovenous hemofiltration.
In 1985 He contributed to the introduction in Europe of high flux dialysis and derived therapies. He also established the dangerous effect of backfiltration in a contaminated dialysis fluid condition.
He has conducted a series of clinical and experimental researches in the following fields:
- Kinetics of fluid and solute removal in peritoneal dialysis and hemodialysis
- Treatment of Acute renal failure with intermittent and continuous therapies
- Renal replacement therapy in the neonate
- Development of new treatment modalities for acute and chronic renal failure.
- Studies on biomaterials
- Studies on glomerular filtration in humans and renal functional reserve
- Renal physiology in pregnancy
- Hydraulics and flow dynamics in the extracorporeal circulation
- Adequacy of dialysis
- Acid-Base Balance in uremia and dialysis
- Acute renal failure and Critical Care Nephrology

Professional employement and Hospital appointments:
Assistant of clinical nephrology from 1977 to 1984 at Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Associate of clinical nephrology from 1984 at Department of Nephrology , St. Bortolo Hospital, Vicenza, Italy.
From 1984 he is director of the hemodialysis and peritoneal dialysis center of the Department of Nephrology at St. Bortolo Hospital, Vicenza, Italy.
From October 25, 1999 to December 1st 2000 Dr. Ronco has been Director of the research laboratory of Hemodialysis at the Beth Israel Medical center of New York and Visiting Professor of Medicine at the Albert Einstein College of Medicine of new York
Today Dr. Ronco is director of the Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.

Board certification: In 1989 he has achieved in Rome, the National License for Nephrology Chair and Directional Functions, with the score 94/100.

Professional Society Membership: He is mamber of the council of several scientific societies and he is editor in chief of the international journal of artificial organs and contributions to nephrology.

Awards and honors:
1983 Schwartz Award, for the best paper of the year at St. Bortolo Hospital.
1984 G.F. Volpato Grant for the best research project on acute renal failure in Italy
1989 Best paper Prize at the Italian Society of nephrology meeting.
1991 ESAO RESEARCH AWARD for the best paper presented at the European Society for Artificial Organs.
1996 Arturo Borsatti Award of Padova University as a best nephrologist of the year.
2004 Lifetime achievement award

Other professional activities: He has organized several congresses and meetings in the area of nephrology and Intensive care from 1982 to today.
He is member of several advisory groups for clinical trials and dialysis research.

Lectures and publications: Dr. Ronco has coauthored 560 papers, 36 book chapters, 26 books, 7 monographic journal issues and has delivered more than 300 lectures in international meetings and universities. His personal impact factor calculated at december 2002 is 391.

Alex Zarbock, MD

Dr. Zarbock is a Clinician Scientist and the Director and Chair of the Department of Anesthesiology and Critical Care Medicine, at the University of Münster, Germany. He acquired training at the University of Münster (Anesthesiology and Critical Care Medicine). Dr. Zarbock is supported by the German Research Foundation. His research interests span various aspects of Critical Care Medicine, but center in critical care nephrology (renal replacement therapy), sepsis and organ protection. Dr. Zarbock’s current projects include measures to avoid acute kidney injury after surgery and the timing of renal replacement therapy in critically ill patients with acute kidney injury. He is also author and co-author of over 140 scientific articles and book chapters.
6:00
Adjourn
Free Evening

Friday, Morning, March 1

7:00am-1:00pm
Conference Registration Open
7:30-8:00
Coffee Served
6:45-8:00
ME5 MEET THE EXPERT
When do I Start RRT in My ICU

Marlies Ostermann, MD

Dr Ostermann is a Consultant in Critical Care & Nephrology at Guy’s & St Thomas’ Foundation Trust, London and Honorary Senior Lecturer at King’s College London. After medical school in Goettingen (Germany), she did her postgraduate training in London and Canada. She holds a PhD degree from the University of Goettingen, an MD degree from the University of London and a postgraduate Diploma in Medical Education. She is an active member of the European Society of Intensive Care Society, Renal Association and Intensive Care Society UK, and a Fellow of the Faculty of Intensive Care Medicine. She is also a co-founder of the London AKI Network. Her research interests include acute kidney injury in critically ill and all aspects of renal replacement therapy.

Claudio Ronco, MD

Actual Position:
Dr. Claudio Ronco
Director
Department of Nephrology
St. Bortolo Hospital
Viale Rodolfi 16
I-36100 Vicenza
Italy

Name: Claudio Ronco

Date of birth: July 12, 1951

Education: High School Diploma at Vicenza Classic Lyceum “A.Pigafetta” in 1970 with the score: 45/60. Dr. Ronco Graduated in Medicine at University of Padua in 1976 with the score 110/110 and merit debating an experimental thesis on title “ Aspects of the Nitrogen metabolism in the nephrotic syndrome”.
From 1973 to 1976 has been intern at Institute of Clinical Internal Medicine I^ of the University of Padua, directed by Prof. E. Fiaschi, in the Nephrology Department II, under the supervision of the Prof. G. Maschio.

Postgraduate training: From July 1976 to November 1977 he has been internal resident at the Division of Internal Medicine of the St. Bortolo Hospital in Vicenza, directed by Prof. D. Corà.
In 1979 he has achieved the Specialization Diploma on Medical Nephrology at The postgraduate school of internal medicine of the University of Padua, with the score 70/70 debating a thesis on the “new methodologies for the measurement of the urinary bicarbonate”
In 1989 he has achieved the Diploma of Specialization in Pediatric Nephrology at University of Naples.
1982: Visiting Fellow at the Mount Sinai Hospital in New York, Department of Internal medicine, Nephrology Division, for four months. He carried out studies on hemofiltration and glomerular filtration with J.P. Bosh, S. Glabman and M. Levitt.
1984: Visiting Physician at the Mount Sinai Hospital In New York for two weeks and at VA Hospital in Los Angeles for two weeks.
1985: Visiting professor at the Nephrology Division of the George Washington University Hospital, Washington DC, and NIH at National Naval Medical Center of Bethesda for three months.
1988: Visiting professor at the Renal and Hypertension Division of George Washington University for three months.
1991: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
1995: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.

Teaching acitivity and Academic Qualifications: From 1978 to 1984 he has been in charge of the teaching program of Nephrology and Dialysis at Professional Nursing School in Vicenza.
During the academic years 1989-01 he has been in charge of teaching “Dialytic therapy” at Specialization School in Medical Nephrology of Padua University where he holds a post of Professor of Nephrology in charge of the teaching program concerning Hemodialysis and renal replacement therapies in critically ill patients.
October 1999-December 2000: Professor of Medicine at Albert Einstein College of Medicine and Director of the Renal laboratory at the Beth israel Medical Center in New York.
In the last ten years Professor Ronco was asked to deliver lectures and seminars in several Universities.
He has delivered in meetings and seminars more than 300 lectures and presentations.

In 1982 he introduced in Italy the use of continuous hemofiltration and in 1986 he published the first series of neonates treated with arteriovenous hemofiltration.
In 1985 He contributed to the introduction in Europe of high flux dialysis and derived therapies. He also established the dangerous effect of backfiltration in a contaminated dialysis fluid condition.
He has conducted a series of clinical and experimental researches in the following fields:
- Kinetics of fluid and solute removal in peritoneal dialysis and hemodialysis
- Treatment of Acute renal failure with intermittent and continuous therapies
- Renal replacement therapy in the neonate
- Development of new treatment modalities for acute and chronic renal failure.
- Studies on biomaterials
- Studies on glomerular filtration in humans and renal functional reserve
- Renal physiology in pregnancy
- Hydraulics and flow dynamics in the extracorporeal circulation
- Adequacy of dialysis
- Acid-Base Balance in uremia and dialysis
- Acute renal failure and Critical Care Nephrology

Professional employement and Hospital appointments:
Assistant of clinical nephrology from 1977 to 1984 at Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Associate of clinical nephrology from 1984 at Department of Nephrology , St. Bortolo Hospital, Vicenza, Italy.
From 1984 he is director of the hemodialysis and peritoneal dialysis center of the Department of Nephrology at St. Bortolo Hospital, Vicenza, Italy.
From October 25, 1999 to December 1st 2000 Dr. Ronco has been Director of the research laboratory of Hemodialysis at the Beth Israel Medical center of New York and Visiting Professor of Medicine at the Albert Einstein College of Medicine of new York
Today Dr. Ronco is director of the Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.

Board certification: In 1989 he has achieved in Rome, the National License for Nephrology Chair and Directional Functions, with the score 94/100.

Professional Society Membership: He is mamber of the council of several scientific societies and he is editor in chief of the international journal of artificial organs and contributions to nephrology.

Awards and honors:
1983 Schwartz Award, for the best paper of the year at St. Bortolo Hospital.
1984 G.F. Volpato Grant for the best research project on acute renal failure in Italy
1989 Best paper Prize at the Italian Society of nephrology meeting.
1991 ESAO RESEARCH AWARD for the best paper presented at the European Society for Artificial Organs.
1996 Arturo Borsatti Award of Padova University as a best nephrologist of the year.
2004 Lifetime achievement award

Other professional activities: He has organized several congresses and meetings in the area of nephrology and Intensive care from 1982 to today.
He is member of several advisory groups for clinical trials and dialysis research.

Lectures and publications: Dr. Ronco has coauthored 560 papers, 36 book chapters, 26 books, 7 monographic journal issues and has delivered more than 300 lectures in international meetings and universities. His personal impact factor calculated at december 2002 is 391.
6:45-8:00
ME6 MEET THE EXPERT
How do I Manage Oliguria

Lui Forni, MD

Matthieu LeGrand, Pr

Pr Matthieu Legrand is Professor of Anesthesiology and Critical care medicine. He holds a PhD in physiology. He Works in the Department of anesthesiology, Critical care and burn unit of St-Louis hospital, university Paris Diderot, France. He has carried preclinical and clinical research in the field of critical care medicine with a special interest in critical care nephrology, sepsis and in burn critical care. He has served as a reviewer for several peer-review journals and expert in the field of critical care for several commitees and task forces.
Breakfast Symposia
6:45-8:00
6:45-8:00
I3. Additional Industry Breakfast Session (Non-CME)
I4. Additional Industry Breakfast Session (Non-CME)
Details


SESSION IV: IMPROVING OUTCOMES IN AKI

Plenary 6 MINI SYMPOSIA
Global Burden of AKI
8:00-10:30

Eisei Noiri, MD., PhD. FASN.

Eisei NOIRI graduated from Hamamatsu University School of Medicine (HUSM) and received PhD at The University of Tokyo under Prof. Kiyoshi Kurokawa. He spent three years in SUNY Stony Brook and BNL under Prof. Michael Goligorsky. He is one of the chief researchers in Division of Nephrology and head of Department of Hemodialysis and Apheresis in The University of Tokyo Hospital. His research interests are broad from basic sciences in AKI pathophysiology, clinical applicability of biomarkers, epidemiology of CRRT, theoretical consideration to CRRT and apheresis therapy, and more.

Marlies Ostermann, MD

Dr Ostermann is a Consultant in Critical Care & Nephrology at Guy’s & St Thomas’ Foundation Trust, London and Honorary Senior Lecturer at King’s College London. After medical school in Goettingen (Germany), she did her postgraduate training in London and Canada. She holds a PhD degree from the University of Goettingen, an MD degree from the University of London and a postgraduate Diploma in Medical Education. She is an active member of the European Society of Intensive Care Society, Renal Association and Intensive Care Society UK, and a Fellow of the Faculty of Intensive Care Medicine. She is also a co-founder of the London AKI Network. Her research interests include acute kidney injury in critically ill and all aspects of renal replacement therapy.
8:00-8:15
Pediatric AKI Around the World: A Neglected Disease?
Room: Coronado Ballroom

Jorge Cerda, MD, MS, FACP, FASN

Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY Clinical Associate Professor of Medicine, Albany Medical College, Albany NY Fulbright Scholar, 1980 Fellow, American College of Physicians Fellow, American Society of Nephrology Organizing Committee, International Conference AKI & CRRT AKI Advisory Group, American Society of Nephrology AKI Committee, and "0by25" Initiative, International Society of Nephrology Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease Associate Editor, Blood Purification and Kidney International Reports Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world
8:15-8:30
Neglected Tropical Diseases and AKI: An Escalating Problem

Emmanuel Burdmann, MD, PhD

Dr. Emmanuel A. Burdmann attended medical school at the University of São Paulo Medical School, São Paulo, Brazil and completed residency in Internal Medicine and fellowships in Nephrology at Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil. He received his Doctorate in Nephrology from the University of São Paulo Medical School and did a post-doc research fellowship at the Nephrology Division of the Oregon Health Sciences University, Portland, Oregon. Dr. Burdmann is the past-president of the Latin-American Society of Nephrology and Hypertension and is currently the president of the Brazilian Society of Nephrology. His current academic position is as Associate Professor of Nephrology at the São José do Rio Preto Medical School, where he is responsible for the care of the AKI patients and for the Post-Graduation Program. Dr Burdmann serves as Associate-Editor in the Clinical Journal of the American Society of Nephrology and in Nephrology, Dialysis, and Transplantation. He is member of AKIN and KDIGO. His research interests centers on acute kidney injury and drugs and animal venoms nephrotoxicity.
8:30-8:45
Long-term Prognosis and Medical Treatment After AKI

Vincent Wu, MD, PhD

Vin-Cent actively involved in the analysis of a database of acute kidney injury in the National Taiwan University Study Group on Acute Renal Failure (NSARF) and Consortium for Acute Kidney Injury and Renal Diseases (CAKs) strive to advance high-quality care in acute kidney injury (AKI) and aspires to plunge the worldwide increasing prevalence of chronic kidney disease (CKD) from the perspective of AKI-CKD transition.
8:45-9:00
Using Mobile Health for Early AKI Recognition

Rolando Claure-Del Granado, MD, FASN

Rolando Claure-Del Granado received his medical degree from Universidad del Valle, School of Medicine, Cochabamba-Bolivia in 1999. His postgraduate training included a residency in Internal Medicine and a Fellowship in Nephrology at the Instituto Nacional de Ciencias Medicas y Nutricion "Salvador Zubiran" (U.N.A.M), Mexico city, Mexico. He was a Research Fellow at the Medicine Department - Division of Nephrology of the University of California San Diego, from 2009 to 2011. Following his fellowship he joined the faculty of Universidad Mayor de San Simon, School of Medicine in Cochabamba - Bolivia as a Professor of Medicine. He is a Clinical Research Investigator at the Biomedical Research Institute (IIBISMED) of the Universidad Mayor de San Simon School of Medicine in Cochabamba - Bolivia. He also is the Head of the Division of Nephrology, Dialysis and Transplantation of Hospital Obrero #2 - C.N.S. in Cochabamba - Bolivia. He is a member of the Acute Kidney Injury Committee of the Latin-American Society of Nephrology and Hypertension. He is the Chair of the Young Nephrologist Committee of the International Society of Nephrology (ISN-YNC) and member of the ISN Latin American Regional Board. He is an active member of the ISN Social Media Task Force. Dr. Claure-Del Granado's research interests include extracorporeal therapies for AKI, the assessment of acid-base metabolic disorders, biomarkers in AKI, and the use of social medial in education.
9:00-9:15
AKI in Southeast Asia: Patterns of Care

Nattachai Srisawat, MD

Current position - Director of Excellence Center for Critical Care Nephrology, King Chulalongkorn Memorial Hospital, Thai Red Cross, Bangkok, Thailand - Division of Nephrology, Department of Medicine, Chulalongkorn University, Bangkok, Thailand - Collaborating CRISMA faculty member Department of Critical Care Medicine, University of Pittsburgh School of Medicine, USA My background: After finishing Nephrology training from Thailand in 2007, He became the part of CRISMA research fellow for 2 years and clinical fellow of Critical Care Medicine for 1 year under mentorship by Professor John A Kellum at Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pennsylvania, USA. He received European Diploma of Intensive Care Medicine in 2012. His main research focused in AKI epidemiology in resource limited setting, novel biomarkers of AKI, and tropical infections causing AKI such as leptospirosis, and dengue infection.
9:15-9:30
Disaster Management for Kidney Patients: What Have We Learnt?

Noel Gibney, MB FRCP(C)

Current Position: Professor, Department of Critical Care Medicine,Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada. Medical School: University College Dublin, Ireland Internal Medicine/Nephrology: St. Vincents Hospital, Dublin, Ireland Pulmonary Medicine: University of Alberta, Edmonton, AB, Canada Critical Care Medicine: Harvard University, Cambridge, MA, USA Interests: CRRT, Sepsis, Information Technology
9:30-9:45
Renal Replacement in Liver Failure: Bridge to Liver Transplant or Liver Regeneration

Akash Deep, Dr

Dr Akash Deep is the Director of the Paediatric Intensive Care Unit(PICU) at King's College Hospital, London and Reader in Paediatric Intensive Care at King’s College London. Dr Deep is the Chair for the Critical Care Nephrology Section of European Society of Paediatric and Neonatal Intensive Care Society (ESPNIC). He has organised and taught on several national and international meetings. Dr Deep is the Chair for the Science and Education Committee of Paediatric Intensive Care Society (PICS) of UK. Dr Deep is the key medical advisor to the UK Sepsis Trust Executive Committee and the main author for the National Paediatric Sepsis Toolkits for Paediatrics. Dr Deep has co-authored the safety netting leaflet for sepsis awareness for parents in the UK. He is the spokesperson on sepsis for the Royal College of Paediatrics and Child Health and the All Party Parliamentary Group on sepsis. Dr Deep has organised many national and international congresses on CRRT and hosted the prestigious 8th International Conference on CRRT in London and the 9th International Conference on CRRT in Orlando, USA. He will be organising Chairman for 2019 U.K’s national Paediatric Intensive Care congress in collaboration with America’s Paediatric Cardiac Intensive Care Society (PCICS) He has authored several research articles in leading peer-reviewed journals and written chapters for leading publishers. He is the Chief Editor for the first ever book published by Springer on ‘’Critical Care Nephrology and Renal Replacement therapy in Children’’. He was awarded the National Bronze award in 2016-17 for his exemplary contribution to the NHS. Special interests include acute liver failure, acute kidney injury, CRRT, haemodynamics in septic shock, sepsis awareness campaigns and liver assist devices in liver failure.
9:45-10:00
Drug-induced AKI: Improving Diagnostic and Preventive Strategies in China

Li Yang, MD

Dr. Yang is an Associate Professor of Medicine in the Renal Division of Peking University First Hospital and Associate Director in the Institute of Nephrology at Peking University, where she directs clinical acute kidney injury, renal pathology, and basic research in nephrology. She is committee member of the International Society of Nephrology Commission on Acute Renal Failure. She received the M.D. degree from Peking University in 2001, and has been on the faculty at Peking University First Hospital since 2001. She was a Research Fellow, granted by the International Society of Nephrology, in the renal division of Brigham and Women’s Hospital at Harvard Medical School, from 2007-2010. Her research interests are in the fields of acute kidney injury, drug associated kidney diseases and renal pathology.
10:00-10:15
Preventing AKI in Resource Poor Regions: The Role of Clean Water

Etienne Macedo, MD, PhD, FASN

Etienne Macedo graduated from the University of Sao Paulo (USP) in Sao Paulo, Brazil. She completed her residency and fellowship through the USP Hospital das Clinicas, and her post-doctorate at the University of California, San Diego, where she continues to work as a clinician and researcher in AKI.
10:15-10:30
Clinical-pathological Correlations in AKI

Rajasekara Chakravarthi, MD, DNB (Nephrology)

Dr. Rajasekara Chakravarthi graduated from Mysore University (MBBS) in 1993 and completed MD (internal medicine) from the same university in 1996. Subsequently he trained as a fellow in Nephrology under the guidance of Dr.M.K.Mani between June 1997 to June 1999. He successfully completed the national board of examinations (Nephrology) DNB-NBE India. He worked as a Consultant Nephrologist at JSS medical college and hospitals Mysore between Aug 1999 to Oct 2000 and then as a Consultant Nephrologist at Apollo hospitals Chennai between Oct 2000 to March 2002. He shifted to the city of Hyderabad in March 2002 and started the department of Nephrology at CARE hospitals, the institute of medical sciences. He was the Head of the department of Nephrology CARE hospitals Banjara hills from March 2002 to September 2011. Since September 2011 till Sep 2015 he officiated as the Director Nephrology services CARE group of hospitals India which is a 16 hospitals group spread across the country. Since Sep 2015 till date he is the director of Nephrology services STAR hospitals, Hyderabad. India. He has keen interest in understanding Acute Kidney Injury and is a member of the AKIN and ADQI (2011, Dublin) (2016, Asiago). He is appointed as faculty of the KDIGO working group on AKI - 2019. He has more than 75 publications in various national and international journals and more than 160 presentations in various conferences. He was a visiting and adjunct faculty to National Institute of Nutrition Hyderabad and JSS University Mysore. He is an organizing committee member and invited faculty for the international CRRT conference held at San Diego yearly since 2005 till date. He is a reviewer for the Indian Journal of nephrology, the official journal of the Indian society of Nephrology, Indian Heart Journal, Journal of Indian College of cardiology, Indian journal of Transplantation and Nephrology and Indian journal of Hypertension. He is presently nominated as a member AKI-committee of the International society of Nephrology. In the year 2016 he has organized and co-chaired the 17th ADQI held at Hyderabad India on Management of AKI in the developing world. He has been organizing AKI and CRRT conferences and works shops since 2004 . He has been part of the active transplantation programme since 1997 at Apollo Hospitals - Chennai, JSS Medical College Hospital - Mysore, Care Group of Hospitals - India and presently at STAR Hospitals - Hyderabad, being part of more than 650 transplantations so far both live related and cadaveric. He is the founding trustee of the NGO, Care For Your Kidney Foundation (cfykf) started in the year 2015 with the aim of creating awareness in the public regarding kidney disease and preventing kidney disease in the community. So far the foundation has completed more than five thousand screening in the urban slums of Hyderabad. The foundation also subsidizes dialysis and kidney transplants for the needy population of the country. He is the founding director of Renown clinical services which is a group offering Nephrology services presently to six hospitals in the city of Hyderabad. An Annual meeting on AKI (acute kidney injury) and CRRT is conducted by Renown associates since 2016 namely Selections from Sandiego. This meeting provides training in all modalities of RRT (dialysis) in ICU and brings the highlights of the AKI and CRRT meeting held annually in Sandiego by CRRT Inc. and UCSD. This meeting held at Sandiego annually is into its 25th year.
10:30-11:00
Coffee Break


SESSION V: FUTURE TRENDS IN CRRT AND CRITICAL CARE

Plenary 7 MINI SYMPOSIA
Emerging Strategies in AKI and Extracorporeal Support
11:00-1:00

Jorge Cerda, MD, MS, FACP, FASN

Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY Clinical Associate Professor of Medicine, Albany Medical College, Albany NY Fulbright Scholar, 1980 Fellow, American College of Physicians Fellow, American Society of Nephrology Organizing Committee, International Conference AKI & CRRT AKI Advisory Group, American Society of Nephrology AKI Committee, and "0by25" Initiative, International Society of Nephrology Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease Associate Editor, Blood Purification and Kidney International Reports Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world

Vincent Wu, MD, PhD

Vin-Cent actively involved in the analysis of a database of acute kidney injury in the National Taiwan University Study Group on Acute Renal Failure (NSARF) and Consortium for Acute Kidney Injury and Renal Diseases (CAKs) strive to advance high-quality care in acute kidney injury (AKI) and aspires to plunge the worldwide increasing prevalence of chronic kidney disease (CKD) from the perspective of AKI-CKD transition.
11:00-12:30
Update from Ongoing and Late Breaking Trials
(12 minutes each)

1. Reducing Intradialytic Hypotension: Colloids vs Crystalloids? - Macedo
2. IV Fluid Resuscitation: The VOLUME-CHASER Study - Kashani
3. ARDS Trials: An Update - Liu
4. Early vs Standard Initiation of RRT: The FST Trial - Sirsawat
5. Complex Interventions for AKI - Lessons from the Tackling AKI Study - Selby
6. Sorbent Based Therapies for MOF - Honore
7. Predicting AKI Recovery: The RUBY Trial - Kellum
Room: Coronado Ballroom

Patrick Honore, MD, PhD

Prof Patrick Honoré, MD,PhD,FCCM Intensivist-Nephrologist Co-Director of ICU Dept and Prof of Medicine Coordinator of Critical Care Research Department Centre Hospitalier Universitaire Brugmann/Brugmann University Hospital B-1020 Brussels (Laeken ) BELGIUM Patrick Honoré, graduated from Louvain Medical School as MD (1988), Specialist in Internal Medicine (1993), Intensive Care Specialist (1994) and Nephrologist (1995). During his internship, he completed more than 2 1/2 years specialisation in Nephrology and Dialysis. For almost 5 years, he received ICU training abroad (United Kingdom, Australia and USA). Pr Honoré is Board member of the Belgian Intensive Care Society and closely involved in the Nephrology section of the European Society of Intensive Care Medicine. He is also a distinguished member or consultant of many scientific committees and decision-making organizations dedicated to diagnosis, treatment, and research in the field of acute kidney injury in the critically ill. Pr Honoré authored or co-authored more than 228 peer-reviewed papers ,more than 600 abstracts and more than 75 book chapters . He was also editor of three books dedicated to Critical Care Nephrology.He has been invited as a speaker at more than 650 national and international conferences in almost 100 different countries. He acts as reviewer for more than 45 international journals, including top-ranking journals in the field of critical care medicine and nephrology. He is a member of the editorial board of several 25 high-standard journals. He is also Editor-In-Chief of the Journal of Translational Internal Medicine (open access) since 2013, editor-in-chief of Journal of Translational Critical Care Medicine & Journal of Translational Kidney Research since 2015 (open access too).He is also appointed as section editor for Renal in Annals of Intensive Care starting from February 2016.Since 2009, he fulltime fulfils the position of Head of Clinics in the Intensive Care department of the University Hospital, Vrije Universiteit Brussels (VUB) and became Clinical Tutor and Senior Lecturer at the VUB Faculty of Medicine.Since 2012, he fulfils the position of Full Professor at the VUB Faculty of Medicine. In the ICU department, he leads the Critical Care Nephrology Platform which incorporates intensivists, nephrologists and nurses dedicated to daily education, research and treatment of acute kidney injury. In particular, he directs and organizes continuous renal replacement therapy on a 24/24; 7/7 on-call basis.He has also start a CRRT program using citrate dedicated to small children (less than 10 kg) in the UZB -PICU since 2013.Since January 2018, he is holding the position of Co-Director of ICU Department , ICU Research Director, Prof of Medicine at CHU-Brugmann University Hospital

Kianoush Kashani, MD

Kianoush Kashani, MD is a consultant in the Division of Nephrology and Hypertension, Division of Pulmonary and Critical Care at Mayo Clinic, Rochester. His academic rank is Professor in Internal Medicine and Assistant Professor in Medical Education. His research interest is acute kidney injury, electrolyte disorders, simulation medicine, and critical care point-of-care ultrasonography.

John Kellum, MD

John A. Kellum, MD, FACP, MCCM John A. Kellum, MD, MCCM is Professor of Critical Care Medicine, Medicine, Bioengineering and Clinical and Translational Science, and Vice Chair for Research within the Department of Critical Care Medicine and Director of the Center for Critical Care Nephrology at the University of Pittsburgh. Dr. Kellum received his medical degree from the Medical College of Ohio in 1984. His postgraduate training includes an internship and residency in Internal Medicine at the University of Rochester, NY, and a Fellowship in Critical Care Medicine at the University of Pittsburgh Medical Center. Dr. Kellum is actively involved in education, research and administration. Dr. Kellum’s research interests span various aspects of Critical Care Medicine, but center in critical care nephrology, sepsis and multi-organ failure, and clinical epidemiology, including consensus development and research methodology. He has authored more than 250 publications and has won several awards for teaching. He lectures widely and has given more than 300 seminars and invited lectures worldwide related to his research.

Kathleen Liu, MD, PhD, MAS

Kathleen D. Liu, MD, PhD, MAS is a Professor in the Departments of Medicine and Anesthesia, Divisions of Nephrology and Critical Care Medicine at the University of California, San Francisco. Dr. Liu graduated from the University of California, San Francisco and trained as a resident at the Brigham and Womens Hospital in Boston. She trained in nephrology and critical care at the University of California, San Francisco. She is board-certified in both nephrology and critical care. Her research interests include biomarkers of kidney disease, acute kidney injury and acute lung injury.

Etienne Macedo, MD, PhD, FASN

Etienne Macedo graduated from the University of Sao Paulo (USP) in Sao Paulo, Brazil. She completed her residency and fellowship through the USP Hospital das Clinicas, and her post-doctorate at the University of California, San Diego, where she continues to work as a clinician and researcher in AKI.

Nick Selby, MD

Dr Selby studied medicine at the University of Nottingham, graduating in 1998, and after completing post-graduate training in the East Midlands was appointed a full-time NHS consultant nephrologist at the Royal Derby Hospital in 2009. In 2015 he was appointed Associate Professor of Nephrology at the University of Nottingham, based in the Centre for Kidney Research and Innovation (www.nottingham.ac.uk/research/groups/renal), Royal Derby Hospital Postgraduate Medical School. Dr. Selby is a clinical academic with primary interests in Acute Kidney Injury (AKI), Magnetic Resonance Imaging (MRI) of the kidney and the haemodynamic consequences of dialysis. He led the development of one of the first e-alert systems for AKI in the UK and is CI on several investigator-instigated studies in these areas. Since 2011 Dr Selby has been awarded peer reviewed grant funding from MRC, the Health Foundation, Kidney Research UK and British Renal Society. He has published over 60 peer-reviewed articles. Dr Selby has several national AKI roles, including leadership of the AKI Clinical Study Group that sits within the UK Kidney Research Consortium, the co-chair of the UK Renal Imaging Network and programme board of the NHS England ‘Think Kidneys’ programme.

Nattachai Srisawat, MD

Current position - Director of Excellence Center for Critical Care Nephrology, King Chulalongkorn Memorial Hospital, Thai Red Cross, Bangkok, Thailand - Division of Nephrology, Department of Medicine, Chulalongkorn University, Bangkok, Thailand - Collaborating CRISMA faculty member Department of Critical Care Medicine, University of Pittsburgh School of Medicine, USA My background: After finishing Nephrology training from Thailand in 2007, He became the part of CRISMA research fellow for 2 years and clinical fellow of Critical Care Medicine for 1 year under mentorship by Professor John A Kellum at Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pennsylvania, USA. He received European Diploma of Intensive Care Medicine in 2012. His main research focused in AKI epidemiology in resource limited setting, novel biomarkers of AKI, and tropical infections causing AKI such as leptospirosis, and dengue infection.
12:30-12:55
Critical Care Nephrology: Literature Review

Noel Gibney, MB FRCP(C)

Current Position: Professor, Department of Critical Care Medicine,Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada. Medical School: University College Dublin, Ireland Internal Medicine/Nephrology: St. Vincents Hospital, Dublin, Ireland Pulmonary Medicine: University of Alberta, Edmonton, AB, Canada Critical Care Medicine: Harvard University, Cambridge, MA, USA Interests: CRRT, Sepsis, Information Technology
12:55-1:00
Closing Remarks

Ravindra Mehta, MBBS, MD, DM, FACP

Dr. Mehta is Professor of Medicine in the Division of Nephrology and Associate Chair for Clinical Affairs in the Department of Medicine at the University of California, San Diego (UCSD) where he directs the Clinical nephrology and dialysis programs. He is also the Chair of the International Society of Nephrology Commission on Acute Renal Failure, founding member of the Acute Dialysis Quality Initiative. He received the M.B.B.S. degree (1976) from the Government Medical School in Amritsar, India, and the M.D. (1979) and D.M. (1981) degrees from the Post Graduate Institute of Medical Education and Research in Chandigarh, India. He subsequently completed a nephrology fellowship at the University of Rochester in Rochester New York and obtained his boards in internal medicine (1986) and Nephrology (1988). He has been on the faculty at San Diego since 1988. His reserach interests are in the field of acute renal failure and he has directed several clinical studies in the management of patients with ARF including comparing different dialytic modalities, conducting large multicenter observational studies of ARF with the PICARD group, evaluating different predictive models for outcomes in ARF, investigating the role of cytokine removal by dialysis membranes in sepsis and ARF, and evaluating techniques for determining the amount of excess fluid in dialysis patients.
1:00
Conference Adjourns
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