1:00-7:00pm
Conference and Workshop Registration Open
Practice Based Learning in CRRT: The Science and the Art
(elective workshop)
This workshop is designed to provide participants with the knowledge and understanding for the effective utilization of CRRT to manage critically ill patients. Session 1 on Sunday focuses on the fundamentals of CRRT including the components, operational characteristics and characteristics, solute and fluid management and monitoring. Session 2 on Monday will utilize case based discussions and interactive sessions to illustrate the underlying concepts for application of CRRT in different situations. Delegates will participate in group exercises to apply their learning for the management of complex cases. At the end of this workshop participants will have an improved understanding of how to utilize CRRT for optimizing renal support. A quiz will be administered pre-and post- course for assessment.
Learning Objectives:
- Describe the underlying concepts and review the process of decision making for prescribing and delivering CRRT
- Learn machine set-up for different modalities, alarm conditions, troubleshooting, monitoring and charting
- Utilize the tools provided to manage complex cases
2 Day CRRT Workshop
1:45-6:00
Jorge Cerda, MD, MS, FACP, FASN
Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY
Clinical Associate Professor of Medicine, Albany Medical College, Albany NY
Fulbright Scholar, 1980
Fellow, American College of Physicians
Fellow, American Society of Nephrology
Organizing Committee, International Conference AKI & CRRT
AKI Advisory Group, American Society of Nephrology
AKI Committee, and "0by25" Initiative, International Society of Nephrology
Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease
Associate Editor, Blood Purification and Kidney International Reports
Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases
Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world
Ashita Tolwani, MD
Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
1:45-2:00
PW2 Opening Remarks
Room: Americas Cup ABCD
Jorge Cerda, MD, MS, FACP, FASN
Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY
Clinical Associate Professor of Medicine, Albany Medical College, Albany NY
Fulbright Scholar, 1980
Fellow, American College of Physicians
Fellow, American Society of Nephrology
Organizing Committee, International Conference AKI & CRRT
AKI Advisory Group, American Society of Nephrology
AKI Committee, and "0by25" Initiative, International Society of Nephrology
Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease
Associate Editor, Blood Purification and Kidney International Reports
Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases
Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world
Ashita Tolwani, MD
Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
2:00-2:30
Pre-Test
Room: Americas Cup ABCD
Jorge Cerda, MD, MS, FACP, FASN
Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY
Clinical Associate Professor of Medicine, Albany Medical College, Albany NY
Fulbright Scholar, 1980
Fellow, American College of Physicians
Fellow, American Society of Nephrology
Organizing Committee, International Conference AKI & CRRT
AKI Advisory Group, American Society of Nephrology
AKI Committee, and "0by25" Initiative, International Society of Nephrology
Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease
Associate Editor, Blood Purification and Kidney International Reports
Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases
Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world
Ashita Tolwani, MD
Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
2:30-3:00
Access, Membrane, Circuit
Room: Americas Cup ABCD
David Selewski, MD
I am an Assistant Professor in the Department of Pediatrics within the Division of Nephrology at the University of Michigan. I received my training in pediatrics and pediatric nephrology at the University of Michigan. My clinical and research interests include pediatric critical care nephrology including pediatric & neonatal acute kidney injury, fluid overload, and continuous renal replacement therapy.
3:00-3:30
Modality & Dose
Room: Americas Cup ABCD
Jorge Cerda, MD, MS, FACP, FASN
Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY
Clinical Associate Professor of Medicine, Albany Medical College, Albany NY
Fulbright Scholar, 1980
Fellow, American College of Physicians
Fellow, American Society of Nephrology
Organizing Committee, International Conference AKI & CRRT
AKI Advisory Group, American Society of Nephrology
AKI Committee, and "0by25" Initiative, International Society of Nephrology
Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease
Associate Editor, Blood Purification and Kidney International Reports
Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases
Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world
3:30-4:00
Anticoagulation
Room: Americas Cup ABCD
Ashita Tolwani, MD
Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
4:00-4:15
Coffee Break
Room: Americas Cup ABCD
4:15-4:45
Solutions and Fluid Balance
Room: Americas Cup ABCD
David Selewski, MD
I am an Assistant Professor in the Department of Pediatrics within the Division of Nephrology at the University of Michigan. I received my training in pediatrics and pediatric nephrology at the University of Michigan. My clinical and research interests include pediatric critical care nephrology including pediatric & neonatal acute kidney injury, fluid overload, and continuous renal replacement therapy.
4:45-5:15
Monitoring
Room: Americas Cup ABCD
Ian Baldwin, RN, PhD, FACCCN
Professor Ian Baldwin; Introduction
Ian is an experienced speaker and presenter from Melbourne, Australia, where he is an Educator for post registration Intensive Care Nursing at the Austin hospital, and has an association with both RMIT and Deakin University as Adjunct Professor.
Ian has undertaken many research activities in the field of renal support therapies and has presented on many occasions in Australia, Asia, the United States and Europe, and is a recipient of the Vicenza 'Award' from the IRRIV, Italy in 2018.
Ian has completed a Masters and PhD in RRT clinical research, and is a past winner of best paper presentations at the Australian Intensive Care Society meetings. Ian has over 110 publications devoted to CRRT and other research activities in critical care and has authored multiple book chapters for AKI and hemofiltration.
Ian is a reviewer for Australian Critical Care, the American Journal of Kidney Diseases,Intensive Care Medicine,and an Associate Editor for Blood Purification.
5:15-6:00
Interactive Case Discussion
Room: Americas Cup ABCD
Ashita Tolwani, MD
Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
7:00am
Conference and Workshop Registration Open
8:00-5:30
Practice Based Learning in CRRT: The Science and the Art
Room: Coronado Ballroom D
Concurrent Physician and Nurse Tracks
Room: Coronado Ballroom
2 Day CRRT Workshop
8:00-5:30
8:00-8:30
PHYSICIAN - Patient Selection
Jorge Cerda, MD, MS, FACP, FASN
Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY
Clinical Associate Professor of Medicine, Albany Medical College, Albany NY
Fulbright Scholar, 1980
Fellow, American College of Physicians
Fellow, American Society of Nephrology
Organizing Committee, International Conference AKI & CRRT
AKI Advisory Group, American Society of Nephrology
AKI Committee, and "0by25" Initiative, International Society of Nephrology
Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease
Associate Editor, Blood Purification and Kidney International Reports
Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases
Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world
8:30-9:00
PHYSICIAN - Drug Dosing and Adjustments
Linda Awdishu, PharmD, MAS
Linda Awdishu earned her Bachelors of Science in Pharmacy from the University of Toronto in 1999, Doctor of Pharmacy from the University of Colorado in 2008 and Masters of Clinical Research from the University of California in 2007. She is an Associate Clinical Professor of Pharmacy and Medicine at UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences. She maintains a clinical practice in the chronic kidney disease program. Her research program is focused on drug induced kidney injury.
9:00-10:00
PHYSICIAN - Management of Acid-Base Disorders with RRT
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Lenar Yessayan, MD, MS
Dr. Yessayan is an Associate Professor of Medicine at the University of Michigan. He is the Medical Director of the Acute Dialysis Program and CRRT at the University of Michigan. He received his bachelor of science in biology and his medical degree from the American University of Beirut in Lebanon. He received his Master of Science in Clinical Research Design and Data Analysis from the University of Michigan in 2013. Dr. Yessayan completed his Internal Medicine Residency and Nephrology and Critical Care Fellowships at Henry Ford Hospital in Detroit, Michigan, USA. He is board certified in Internal Medicine, Nephrology, and Critical Care Medicine and been practicing since 2009. His research interests lie in the fields of acute kidney injury, hemodynamic monitoring, medical device therapies to treat systemic inflammatory conditions and development of effluent sensing technologies for real time monitoring of solutes during extracorporeal therapies
10:00-10:20
Coffee Break
10:20-10:50
PHYSICIAN - Management of Dysnatremias with RRT
Lenar Yessayan, MD, MS
Dr. Yessayan is an Associate Professor of Medicine at the University of Michigan. He is the Medical Director of the Acute Dialysis Program and CRRT at the University of Michigan. He received his bachelor of science in biology and his medical degree from the American University of Beirut in Lebanon. He received his Master of Science in Clinical Research Design and Data Analysis from the University of Michigan in 2013. Dr. Yessayan completed his Internal Medicine Residency and Nephrology and Critical Care Fellowships at Henry Ford Hospital in Detroit, Michigan, USA. He is board certified in Internal Medicine, Nephrology, and Critical Care Medicine and been practicing since 2009. His research interests lie in the fields of acute kidney injury, hemodynamic monitoring, medical device therapies to treat systemic inflammatory conditions and development of effluent sensing technologies for real time monitoring of solutes during extracorporeal therapies
10:50-11:20
PHYSICIAN - Adjusting Nutrition
Javier Neyra
11:20-11:40
PHYSICIAN - Intraoperative CRRT
Andrew Barker, MD
11:40-12:00
PHYSICIAN - Achieving Survival and Recovery
Scott Sutherland, MD
Scott M. Sutherland, MD is a Clinical Professor of Pediatric Nephrology at the Lucile Packard Children's Hospital / Stanford University Medical Center. He is the medical director for apheresis and acute dialysis therapies and co-directs the Cardiorenal Clinic. His research interests include intensive care nephrology, AKI, CRRT, and fluid overload.
8:00-8:40
NURSE - Orders, Charting and Monitoring
Ian Baldwin, RN, PhD, FACCCN
Professor Ian Baldwin; Introduction
Ian is an experienced speaker and presenter from Melbourne, Australia, where he is an Educator for post registration Intensive Care Nursing at the Austin hospital, and has an association with both RMIT and Deakin University as Adjunct Professor.
Ian has undertaken many research activities in the field of renal support therapies and has presented on many occasions in Australia, Asia, the United States and Europe, and is a recipient of the Vicenza 'Award' from the IRRIV, Italy in 2018.
Ian has completed a Masters and PhD in RRT clinical research, and is a past winner of best paper presentations at the Australian Intensive Care Society meetings. Ian has over 110 publications devoted to CRRT and other research activities in critical care and has authored multiple book chapters for AKI and hemofiltration.
Ian is a reviewer for Australian Critical Care, the American Journal of Kidney Diseases,Intensive Care Medicine,and an Associate Editor for Blood Purification.
8:40-9:20
NURSE - CRRT in the Operating Room
Andrew Barker, MD
9:20-10:00
NURSE - CRRT for Pediatric Applications
Theresa Mottes, MSN, RN,CPNP-AC,CDN
Theresa Mottes has over 20 years of pediatric renal replacement therapy experience is both the critical care setting and the outpatient dialysis setting. She has been involved in research with acute kidney injury, continuous renal replacement therapies and simulation based education for CRRT training. Theresa currently is a nurse practitioner for critical care nephrology. Theresa is very active with ANNA, as the current Pediatric Specialty Practice Network facilitator. She has presented at both national and international conferences.
10:00-10:20
Coffee Break
10:20-11:00
NURSE - Patient Mobilization and Rehabilitation
Ian Baldwin, RN, PhD, FACCCN
Professor Ian Baldwin; Introduction
Ian is an experienced speaker and presenter from Melbourne, Australia, where he is an Educator for post registration Intensive Care Nursing at the Austin hospital, and has an association with both RMIT and Deakin University as Adjunct Professor.
Ian has undertaken many research activities in the field of renal support therapies and has presented on many occasions in Australia, Asia, the United States and Europe, and is a recipient of the Vicenza 'Award' from the IRRIV, Italy in 2018.
Ian has completed a Masters and PhD in RRT clinical research, and is a past winner of best paper presentations at the Australian Intensive Care Society meetings. Ian has over 110 publications devoted to CRRT and other research activities in critical care and has authored multiple book chapters for AKI and hemofiltration.
Ian is a reviewer for Australian Critical Care, the American Journal of Kidney Diseases,Intensive Care Medicine,and an Associate Editor for Blood Purification.
Michael Connor, MD
Dr. Connor is dual trained in nephrology & critical care medicine sharing his clinical duties between critical care medicine & inpatient consultative nephrology. Dr. Connor’s clinical and academic interests are focused heavily on critical care medicine and especially acute nephrology issues in the critically ill. Dr. Connor is an internationally recognized expert on acute renal replacement therapies, acute kidney injury (AKI), antimicrobial dosing in AKI, volume management and hemodynamic support of the critically ill, intra-abdominal hypertension & abdominal compartment syndrome, acute acid/base derangements, and extracorporeal blood purification techniques including extra-corporeal membrane oxygenation.
In September 2014, Dr. Connor spearheaded the first-ever application of advanced critical care support to a patient with Ebola virus disease (EVD) which included the first known successful application of acute continuous hemodialysis and mechanical ventilatory support in EVD.
11:00-11:40
NURSE - Integrating Multidisciplinary Support Team for CRRT Delivery
Linda Awdishu, PharmD, MAS
Linda Awdishu earned her Bachelors of Science in Pharmacy from the University of Toronto in 1999, Doctor of Pharmacy from the University of Colorado in 2008 and Masters of Clinical Research from the University of California in 2007. She is an Associate Clinical Professor of Pharmacy and Medicine at UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences. She maintains a clinical practice in the chronic kidney disease program. Her research program is focused on drug induced kidney injury.
Ian Baldwin, RN, PhD, FACCCN
Professor Ian Baldwin; Introduction
Ian is an experienced speaker and presenter from Melbourne, Australia, where he is an Educator for post registration Intensive Care Nursing at the Austin hospital, and has an association with both RMIT and Deakin University as Adjunct Professor.
Ian has undertaken many research activities in the field of renal support therapies and has presented on many occasions in Australia, Asia, the United States and Europe, and is a recipient of the Vicenza 'Award' from the IRRIV, Italy in 2018.
Ian has completed a Masters and PhD in RRT clinical research, and is a past winner of best paper presentations at the Australian Intensive Care Society meetings. Ian has over 110 publications devoted to CRRT and other research activities in critical care and has authored multiple book chapters for AKI and hemofiltration.
Ian is a reviewer for Australian Critical Care, the American Journal of Kidney Diseases,Intensive Care Medicine,and an Associate Editor for Blood Purification.
11:40-12:00
NURSE - Developing Quality Measures for CRRT Delivery
Theresa Mottes, MSN, RN,CPNP-AC,CDN
Theresa Mottes has over 20 years of pediatric renal replacement therapy experience is both the critical care setting and the outpatient dialysis setting. She has been involved in research with acute kidney injury, continuous renal replacement therapies and simulation based education for CRRT training. Theresa currently is a nurse practitioner for critical care nephrology. Theresa is very active with ANNA, as the current Pediatric Specialty Practice Network facilitator. She has presented at both national and international conferences.
Javier Neyra
12:00-1:00
Lunch Hosted by Conference for Workshop Participants
1:10-4:00
Interactive Physician and Nurse Tracks
These sessions will have nurses, physicians and pediatric tracks. Physicians will be guided on user interfaces and the strategies for prescribing dose for solute and fluid management, adjustments in therapy parameters, recognition and management of complications. Nurses will learn how to set up for different modalities and adjust and monitor for therapy delivery based on the prescription.
Room: Coronado Ballroom D
1:10-4:00
PHYSICIAN - Circuit, Anticoagulation and Monitoring
Ashita Tolwani, MD
Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
Lenar Yessayan, MD, MS
Dr. Yessayan is an Associate Professor of Medicine at the University of Michigan. He is the Medical Director of the Acute Dialysis Program and CRRT at the University of Michigan. He received his bachelor of science in biology and his medical degree from the American University of Beirut in Lebanon. He received his Master of Science in Clinical Research Design and Data Analysis from the University of Michigan in 2013. Dr. Yessayan completed his Internal Medicine Residency and Nephrology and Critical Care Fellowships at Henry Ford Hospital in Detroit, Michigan, USA. He is board certified in Internal Medicine, Nephrology, and Critical Care Medicine and been practicing since 2009. His research interests lie in the fields of acute kidney injury, hemodynamic monitoring, medical device therapies to treat systemic inflammatory conditions and development of effluent sensing technologies for real time monitoring of solutes during extracorporeal therapies
1:10-4:00
PHYSICIAN - Dose / Fluid / Documentation / Recognizing and Managing Complications
Michael Connor, MD
Dr. Connor is dual trained in nephrology & critical care medicine sharing his clinical duties between critical care medicine & inpatient consultative nephrology. Dr. Connor’s clinical and academic interests are focused heavily on critical care medicine and especially acute nephrology issues in the critically ill. Dr. Connor is an internationally recognized expert on acute renal replacement therapies, acute kidney injury (AKI), antimicrobial dosing in AKI, volume management and hemodynamic support of the critically ill, intra-abdominal hypertension & abdominal compartment syndrome, acute acid/base derangements, and extracorporeal blood purification techniques including extra-corporeal membrane oxygenation.
In September 2014, Dr. Connor spearheaded the first-ever application of advanced critical care support to a patient with Ebola virus disease (EVD) which included the first known successful application of acute continuous hemodialysis and mechanical ventilatory support in EVD.
Scott Sutherland, MD
Scott M. Sutherland, MD is a Clinical Professor of Pediatric Nephrology at the Lucile Packard Children's Hospital / Stanford University Medical Center. He is the medical director for apheresis and acute dialysis therapies and co-directs the Cardiorenal Clinic. His research interests include intensive care nephrology, AKI, CRRT, and fluid overload.
1:10-4:00
PHYSICIAN - Prescription / Order Sets / Decision Making / Coordination of Care
Jorge Cerda, MD, MS, FACP, FASN
Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY
Clinical Associate Professor of Medicine, Albany Medical College, Albany NY
Fulbright Scholar, 1980
Fellow, American College of Physicians
Fellow, American Society of Nephrology
Organizing Committee, International Conference AKI & CRRT
AKI Advisory Group, American Society of Nephrology
AKI Committee, and "0by25" Initiative, International Society of Nephrology
Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease
Associate Editor, Blood Purification and Kidney International Reports
Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases
Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world
Javier Neyra
1:10-4:00
PHYSICIAN - Monitoring, Alarms and Connections with Other Therapies
Katrina Eggleston, MSN, RN
Katrina has been working in acute dialysis for over 14 years as a preceptor and charge nurse. She now holds the position of Manager of CRRT, traveling to acute facilities training their staff on CRRT.
Keith Wille, MD
Keith Wille, MD, MSPH is currently a Professor of Medicine at the University of Alabama at Birmingham (UAB). Dr. Wille completed fellowship training in Pulmonary and Critical Care Medicine at UAB and joined the faculty in 2000. His clinical interests are in critical care medicine, extracorporeal support technologies, and cardiothoracic transplantation. He received an MSPH degree in clinical epidemiology from the UAB School of Public Health in 2013 and is currently pursuing a degree in Healthcare Quality and Safety. He is Medical Director of the UAB Adult ECMO and Advanced Lung Diseases Programs and organizes the UAB Extracorporeal Life Support Symposium.
1:10-4:00
NURSE - Machine Priming, Circuit Set Up, Programing to Match Orders
Katrina Eggleston, MSN, RN
Katrina has been working in acute dialysis for over 14 years as a preceptor and charge nurse. She now holds the position of Manager of CRRT, traveling to acute facilities training their staff on CRRT.
1:10-4:00
NURSE - Implementing Therapy Delivery Dose Adjustments, Fluid Balance
Ian Baldwin, RN, PhD, FACCCN
Professor Ian Baldwin; Introduction
Ian is an experienced speaker and presenter from Melbourne, Australia, where he is an Educator for post registration Intensive Care Nursing at the Austin hospital, and has an association with both RMIT and Deakin University as Adjunct Professor.
Ian has undertaken many research activities in the field of renal support therapies and has presented on many occasions in Australia, Asia, the United States and Europe, and is a recipient of the Vicenza 'Award' from the IRRIV, Italy in 2018.
Ian has completed a Masters and PhD in RRT clinical research, and is a past winner of best paper presentations at the Australian Intensive Care Society meetings. Ian has over 110 publications devoted to CRRT and other research activities in critical care and has authored multiple book chapters for AKI and hemofiltration.
Ian is a reviewer for Australian Critical Care, the American Journal of Kidney Diseases,Intensive Care Medicine,and an Associate Editor for Blood Purification.
Javier Neyra
1:10-4:00
NURSE - Therapy Monitoring and Troubleshooting Alarms, Therapy Discontinuation
Ian Baldwin, RN, PhD, FACCCN
Professor Ian Baldwin; Introduction
Ian is an experienced speaker and presenter from Melbourne, Australia, where he is an Educator for post registration Intensive Care Nursing at the Austin hospital, and has an association with both RMIT and Deakin University as Adjunct Professor.
Ian has undertaken many research activities in the field of renal support therapies and has presented on many occasions in Australia, Asia, the United States and Europe, and is a recipient of the Vicenza 'Award' from the IRRIV, Italy in 2018.
Ian has completed a Masters and PhD in RRT clinical research, and is a past winner of best paper presentations at the Australian Intensive Care Society meetings. Ian has over 110 publications devoted to CRRT and other research activities in critical care and has authored multiple book chapters for AKI and hemofiltration.
Ian is a reviewer for Australian Critical Care, the American Journal of Kidney Diseases,Intensive Care Medicine,and an Associate Editor for Blood Purification.
1:10-4:00
NURSE - Connectology with Hybrid Systems ECMO, ECCOR, Apheresis
Michael Connor, MD
Dr. Connor is dual trained in nephrology & critical care medicine sharing his clinical duties between critical care medicine & inpatient consultative nephrology. Dr. Connor’s clinical and academic interests are focused heavily on critical care medicine and especially acute nephrology issues in the critically ill. Dr. Connor is an internationally recognized expert on acute renal replacement therapies, acute kidney injury (AKI), antimicrobial dosing in AKI, volume management and hemodynamic support of the critically ill, intra-abdominal hypertension & abdominal compartment syndrome, acute acid/base derangements, and extracorporeal blood purification techniques including extra-corporeal membrane oxygenation.
In September 2014, Dr. Connor spearheaded the first-ever application of advanced critical care support to a patient with Ebola virus disease (EVD) which included the first known successful application of acute continuous hemodialysis and mechanical ventilatory support in EVD.
Isagani Marquez, MSN, RN, QIA
1:10-4:00
PEDIATRIC SESSION
Modality Selection, Circuit Modifications, Therapy Dosing, Monitoring, Adjustments for Targeted Interventions
Theresa Mottes, MSN, RN,CPNP-AC,CDN
Theresa Mottes has over 20 years of pediatric renal replacement therapy experience is both the critical care setting and the outpatient dialysis setting. She has been involved in research with acute kidney injury, continuous renal replacement therapies and simulation based education for CRRT training. Theresa currently is a nurse practitioner for critical care nephrology. Theresa is very active with ANNA, as the current Pediatric Specialty Practice Network facilitator. She has presented at both national and international conferences.
Zaccaria Ricci, MD
Education and training:
Graduation in Medicine on September 1997 at University of “La Sapienza” of Rome, Italy. Specialization in Anesthesiology and Intensive Care on October 2001 at University of “La Sapienza” of Rome, Italy.
Professional experience:
Zaccaria Ricci matured experience in critical care during his period from 2001 to 2006 as a staff clinician in the Intensive Care Unit of the Policlinico Umberto I at the University “La Sapienza” of Rome, Italy. His areas of interest included pharmacological strategies and renal replacement therapies for critically ill patients with acute kidney injury.
His interest and expertise on extracorporeal therapies and blood purification developed in collaboration with the Department of Nephrology Dialysis and Transplantation, Vicenza, Italy, directed by professor Claudio Ronco. In particular, he has focused its main interest in Renal Replacement Dose Delivery and Information Technology applied to new generation machines for acute dialysis. He had the privilege of co-conducting the alpha trials of the Prismaflex and the Carpediem machines.
Since 2006 he is a staff anesthesiologist of the Department of Pediatric Cardiac Surgery at Bambino Gesù Hospital. His work has been devoted to the care of pediatric renal dysfunction and hemodynamic monitoring in the perioperative care of children with congenital heart diseases.
He is author and coauthor of about 200 original articles, reviews and book chapters in the field acute kidney injury diagnosis and therapy and pediatric critical care. He is currently collaborating as a peer reviewer with more than 10 indexed journals in the area of Critical Care and Nephrology. Since October 2009 he is an Associated Faculty Member of Pediatric Critical Care Medicine and in the Editorial Board of the journal Blood Purification. Since October 2013 he is an Associate Editor of the journal BMC Anesthesiology.
David Selewski, MD
I am an Assistant Professor in the Department of Pediatrics within the Division of Nephrology at the University of Michigan. I received my training in pediatrics and pediatric nephrology at the University of Michigan. My clinical and research interests include pediatric critical care nephrology including pediatric & neonatal acute kidney injury, fluid overload, and continuous renal replacement therapy.
4:15-4:55
Interactive Clinical Case (Decision Making)
Ashita Tolwani, MD
Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
5:00-5:30
Post Course Test and Wrap-up
Jorge Cerda, MD, MS, FACP, FASN
Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY
Clinical Associate Professor of Medicine, Albany Medical College, Albany NY
Fulbright Scholar, 1980
Fellow, American College of Physicians
Fellow, American Society of Nephrology
Organizing Committee, International Conference AKI & CRRT
AKI Advisory Group, American Society of Nephrology
AKI Committee, and "0by25" Initiative, International Society of Nephrology
Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease
Associate Editor, Blood Purification and Kidney International Reports
Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases
Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world
Ashita Tolwani, MD
Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
5:30pm
Adjourn
Pre-Conference AKI Symposium
7:55-5:30
PW1 Changing Paradigms in Acute Kidney Injury:
From Mechanisms to Management
sponsored by:
The UAB-UCSD O'Brien Core Center for
Kidney Injury Research
Acute Kidney Injury is a rapidly evolving area where several advances have been made in understanding the mechanisms and pathways of AKI and its effects on other organs. Recent identification of biomarkers has provided new tools and techniques to characterize this disorder. This pre-course workshop will provide a comprehensive review of the most recent developments in the field and describe emerging knowledge from basic and translational research. Results from clinical trials will be discussed to define the best strategies for effective management of patients and define the criteria for future studies.
CRRT Conference registration is not required to attend this symposium, separate registration is available.
Room: Coronado Ballroom E
7:55-8:00
Opening Remarks
Room: Coronado Ballroom E
Ravindra Mehta, MBBS, MD, DM, FACP
Dr. Mehta is Professor of Medicine in the Division of Nephrology and Associate Chair for Clinical Affairs in the Department of Medicine at the University of California, San Diego (UCSD) where he directs the Clinical nephrology and dialysis programs. He is also the Chair of the International Society of Nephrology Commission on Acute Renal Failure, founding member of the Acute Dialysis Quality Initiative. He received the M.B.B.S. degree (1976) from the Government Medical School in Amritsar, India, and the M.D. (1979) and D.M. (1981) degrees from the Post Graduate Institute of Medical Education and Research in Chandigarh, India. He subsequently completed a nephrology fellowship at the University of Rochester in Rochester New York and obtained his boards in internal medicine (1986) and Nephrology (1988). He has been on the faculty at San Diego since 1988. His reserach interests are in the field of acute renal failure and he has directed several clinical studies in the management of patients with ARF including comparing different dialytic modalities, conducting large multicenter observational studies of ARF with the PICARD group, evaluating different predictive models for outcomes in ARF, investigating the role of cytokine removal by dialysis membranes in sepsis and ARF, and evaluating techniques for determining the amount of excess fluid in dialysis patients.
AKI Symposium - Plenary 1
Molecules, Mechanisms and Targets
8:00-10:00
Anupam Agarwal, MD
Anupam Agarwal, MD Professor of Medicine, Director, Division of Nephrology. Dr. Agarwal's research program has provided critical insights regarding the cytoprotective nature and significance of heme oxygenase-1 (HO-1) in vascular and renal inflammation, angiogenesis, transplant biology, and the molecular regulation of the human HO-1 gene. Dr. Agarwal's research efforts include three main areas. (i) His laboratory is studying the molecular regulation of the human heme oxygenase-1 (HO-1) gene in renal injury, transplant rejection, diabetic vascular disease and in atherosclerosis. Studies are also exploring the cellular mechanisms involved in the protective effects of the HO-1 enzyme in renal and vascular injury. Induction of this gene occurs as an adaptive and beneficial response to injury and is protective in several clinically important conditions such as acute renal failure, transplant rejection and atherosclerosis. Studies are focused on identifying regulatory regions in the human HO-1 gene that mediate induction in response to stimuli such as heme, cytokines, nitric oxide, modified lipids and growth factors (eg. transforming growth factor-beta). The studies involve molecular biology techniques to study DNA-protein interactions using chromatin structure analysis, in vivo footprinting, site-directed mutagenesis and gel shift assays. His laboratory is also studying the molecular and biological effects of nitrated lipids on HO-1 gene expression in endothelial cells and in the vasculature. (ii) The functional significance of HO-1 gene expression is also being evaluated using both in vitro and in vivo systems in transgenic animal models of acute kidney injury, immune-mediated injury in the setting of transplantation, diabetes and atherosclerosis. (iii) His laboratory is actively pursuing gene delivery approaches in the kidney and the vasculature in animal models of transplantation and diabetes using recombinant adeno-associated viral vectors. Alternate serotypes and capsid mutants of adeno-associated viral vectors are being developed to maximize gene transfer to the otherwise resistant vascular compartment with a goal towards targeting diabetic micro and macrovascular disease.
Volker Vallon, MD
Dr. Vallon is Professor of Medicine and Pharmacology at UCSD and a principal investigator at the VA San Diego Healthcare System. He received his M.D. from the University of Tuebingen, Germany, in 1992, and research training at the University of Tuebingen, UCSD, and the NIH. He joined the faculty at the University of Tuebingen in 1998, and at UCSD in 2003. His group has characterized the roles played by a variety of channels, transporters, receptors and signaling molecules in the physiology, pathophysiology, and pharmacology of the kidney. He aims to integrate aspects of vascular, glomerular and tubular function to gain a more complete understanding of the physiology and pharmacology of the kidney as well as the pathophysiology of acute kidney injury, arterial hypertension and the diabetic kidney.
8:00-8:20
GSK3 Signaling in AKI
Room: Coronado Ballroom E
Reena Rao, MD
8:20-8:40
Role of Proximal Tubular Kru_ppel-like Factor 6 (KLF6) in AKI
Room: Coronado Ballroom E
Sian Piret, PhD
Dr Sian Piret is a Research Assistant Professor in the Department of Medicine at Stony Brook University, NY, USA. She completed both her Master of Biochemistry (2003) and PhD (2008) at the University of Oxford, UK. Her PhD and Post-Doctoral studies focused on understanding the mechanisms of inherited renal disorders including autosomal dominant tubulointerstitial kidney disease due to mutations in the UMOD gene (ADTKD-UMOD) and Dent’s disease. Her current work with Dr Sandeep Mallipattu is exploring the role of transcriptional regulation, and particularly the transcription factor Krüppel-like Factor 6, in AKI and CKD.
8:40-9:00
Iron Homeostasis in Sepsis Induced AKI
Room: Coronado Ballroom E
Subhashini Bolisetty, PhD
Dr. Subhashini Bolisetty is currently an Assistant Professor in the Division of Nephrology at the University of Alabama at Birmingham (UAB). Dr. Bolisetty’s research program focuses on the role of ferritin and iron metabolism during kidney injury. Her biography includes 36 peer-reviewed manuscripts, a book chapter and several reviews, the former appearing in journals such as the Journal of Clinical Investigation, Proceedings of the National Academy of Sciences, Journal of Biological Chemistry, Kidney International, Circulation Research, Journal of the American Society of Nephrology as well as others. She is a recipient of several awards including the Joseph Reeves award for excellence in research. Her research has been funded by multiple sources including the American Heart Association, NIH and ASN. Dr. Bolisetty has been invited to present at national and international meetings including the American Society of Nephrology and International conferences on HO and BioIron. Dr. Bolisetty has an active role in teaching, research and mentorship in the UAB graduate school. She participates in several teaching courses for graduate students and medical students. She also serves as a founding member of the UAB Early Career Peer Mentoring group, which helps to facilitate transition of postdoctoral scholars to independence. She serves as an Editor for the Renal Iron Handling In Health and Disease research topic for Frontiers in Immunology and also serves as a reviewer for multiple journals including the Journal of the American Society of Nephrology, American Journal of Physiology - Renal Physiology and Frontiers in Immunology as well as others.
9:00-9:20
Pertibular Capillary Oxygen Consumption: Studies Using Photoacoustic Microscopy
Room: Coronado Ballroom E
Mark Okusa, MD
Mark D. Okusa, M.D. is the John C. Buchanan Distinguished Professor of Medicine, Chief, Division of Nephrology and Director, Center for Immunity, Inflammation and Regenerative Medicine at the University of Virginia, Charlottesville, VA. He received his M.D., and internship and residency training at the Medical College of Virginia, Richmond, VA followed by clinical and research nephrology training at Yale University, New Haven, CT. Dr. Okusa joined the faculty at the University of Virginia in 1991 as a clinician investigator combining clinical care, education and research. His clinical and research interest focus on acute kidney injury. He is the principal investigator of several NIH grants including a T32 training grant. He has published over 130 original manuscripts and book chapters. He has served on advisory committees and study sections for the NIH, ASN, AHA, and NKF and as Chair of the Program Committee of the ASN (2011). Dr. Okusa was the Associate Editor of Nephron Physiology, and Kidney International and current member of the editorial boards of the American Journal of Physiology:Renal Physiology, American Journal of Nephrology, Kidney International and Journal of the American Society of Nephrology. Dr. Okusa has been listed in Castle Connallys Americas Top Doctors (2001-2014), member of the American Clinical and Climatological Association and elected Councilor to the American Society of Nephrology in 2012.
9:20-9:40
Harnessing Endogenous T Regulatory Cells in AKI
Room: Coronado Ballroom E
Rahul Sharma, PhD
Dr. Sharma has been studying end-organ failure and inflammation in systemic autoimmune diseases for 15 years. His recent work has identified novel pathways for homeostasis of T-regulatory (Treg) cells leading to generation of a novel propriety reagent (US patent granted, 2017), which inhibits inflammation and induced a regenerative program in the kidneys and pancreas utilizing both immune-dependent and independent mechanisms showing persistent remission in preclinical studies on autoimmune (lupus nephritis and type-1 diabetes) and inflammatory diseases (acute kidney injury and diabetic nephropathy). His laboratory also studies the role of checkpoint inhibitors in Treg function and metabolism. Their group is validating these pathways in acute kidney injury in cardiac surgery patients. His laboratory also investigates the contribution of defective clearance of extra-nuclear DNA in loss of tolerance and autoimmunity. His laboratory is supported by awards from NIH and non-profit foundations. His graduate work was the first in the history of Indian Biotechnology to be translated for production of protein pharmaceuticals, is in use for patient care and was awarded the National Technology Award by the Government of India. Dr. Sharma serves on review committees for Veterans administration and National Institutes of Health and is on the editorial board of Frontiers in Pharmacology - Renal, Modern Research in Inflammation and Advances in Medicine-Immunology. As an educator he is the course director of Immunology for the UVA School of Medicine's next generation curriculum.
9:40-10:00
Discussion
Room: Coronado Ballroom E
10:00-10:15
Coffee Break
AKI Symposium - Plenary 2
Harmonizing Human and Animal AKI: Results from ADQI 13
10:15-12:15
Paul Sanders, MD
Dr. Paul W. Sanders is Professor of Medicine and holder of the Thomas E. Andreoli Endowed Chair in Nephrology at the University of Alabama at Birmingham (UAB). He is also Chief of the Renal Section at the Birmingham Veterans Affairs Medical Center and is Director of the Nephrology Research and Training Center at UAB. After completing a residency in Internal Medicine and fellowship in Nephrology at UAB, Dr. Sanders has remained on faculty and has risen in the ranks to his present position. He has received a number of honors that include election into Alpha Omega Alpha and the American Society for Clinical Investigation. He is Fellow of the American College of Physicians and American Heart Association. His research has been funded for more than two decades by the Department of Veterans Affairs and by the National Institutes of Health. Dr. Sanders has served on numerous grant review committees for the National Institutes of Health, National Kidney Foundation, American Heart Association, American Society of Nephrology, and the Department of Veterans Affairs. He has authored 103 peer-reviewed articles and 47 book chapters and editorials that describe the vascular and renal alterations associated with dietary salt intake and the mechanism(s) of acute and chronic kidney injury induced by immunoglobulin light chains.
Prabhleen Singh, MD
Dr. Singh is an Assistant Professor of Medicine in the Division of Nephrology-Hypertension at the University of California San Diego and VA San Diego Healthcare system. She received her MBBS degree from Nagpur University, India and subsequently completed residency and nephrology fellowship training at the University of Alabama, Birmingham and University of California, San Diego (UCSD). She joined the faculty at UCSD in 2009 and is supported by a NIH K08 mentored clinical scientist research career development award.
Her research interest is focused on elucidating the key renal hemodynamic and metabolic adaptations including mitochondrial function at the onset of acute kidney injury and chronic kidney disease which play a key role in the pathophysiology of disease progression. Well-established physiological techniques, such as renal micropuncture, which offers the opportunity to study single nephron function in an intact kidney and in-vivo whole-kidney oxygen consumption, are utilized in experimental models to answer clinically relevant questions. Clinical interests include ICU nephrology and acute kidney injury.
10:15-10:35
Intravital Imaging to Study Tubular Regeneration After AKI
Room: Coronado Ballroom E
Ina Maria Schiessl, PhD
Ina Maria Schiessl is a pharmacist, who dedicated her professional career to basic medical research and has been working in the field of renal physiology and pathophysiology since 2011. Her signature approach is serial intravital 2-photon microscopy of the kidney, which is a powerful technique to study renal structure and function simultaneously and over several days in the same living animal. She did her scientific training at the University or Regensburg, Germany and at the University of Southern California, USA, where she studied new mechanisms of renal tissue remodeling and repair. Using serial intravital microscopy of the same renal cells over days, she recently postulated a novel role of renal interstitial cells in tubular regeneration. Currently, she is an Assistant Professor at Aarhus University in Denmark. With her own research program, she aims to broaden our understanding of renal intercellular crosstalk and its relevance in renal tissue remodeling and repair.
10:35-10:55
Cellular and Molecular Pathways of Renal Repair After Acute Kidney Injury
Room: Coronado Ballroom E
Sanjeev Kumar, MD
10:55-11:15
Acute Cardio Renal Syndrome: Mapping the Heart Kidney Interactions
Room: Coronado Ballroom E
Michael Hutchens, MD
I am an anesthesiology-trained clinician-scientist whose interest in acute cardiorenal syndrome and transition to CKD is driven by clinical experience in cardiovascular and surgical critical care. My basic science work, primarily carried out in a mouse model of cardiac arrest and cardiopulmonary resuscitation, now focuses on heart-to-kidney signaling and early alterations in tubular epithelial function which may lead to long-term change.
11:15-11:35
Angiopoietin-TIE2 Receptor Tyrosine Kinase Signaling in Kidney Injury
Room: Coronado Ballroom E
Susan Quaggin
11:35-11:55
Organelle Cross Talk in AKI
Room: Coronado Ballroom E
Reiko Inagi, PhD
Prof. Reiko Inagi is a Division Chief at the University of Tokyo Graduate School of Medicine. She earned her Ph.D. in Immunology from Nagoya University Graduate School of Medicine, Nagoya, Japan, in 1990. She has researched the mechanisms of latent viral infection and host defense at Osaka University School of Medicine as an associate professor from 1991 to 1998. She then moved to Tokai University School of Medicine as an associate professor and began her studies on molecular nephrology, including genomics and transcriptome analyses for identification of the novel genes specific for kidney disease. She got the “Kimoto Award” of the Japanese Society for Dialysis Therapy in 2003, the awards of the Japanese Society for Renal Pathology in 2003 and 2007. Since 2008, she has been assigned to the Senior researcher (2008-2013, Division of Nephrology and Endocrinology) and the present positions (2013~), and her recent professional interests are i) the role of oxidative, hypoxic, or endoplasmic reticulum stress-induced responses, ii) the link between organelle-induced stress signals and uremic toxins, iii) pathophysiological significance of organelle crosstalk in kidney disease and aging. She has published over 200 papers (including 58 reviews and textbooks) in the top international journals and has been invited to many international academic meetings, including International Society of Nephrology, Asian Pacific Congress of Nephrology, American Society of Nephrology, and FASEB meeting. She is a scientific program committee of Kidney Week 2020 and Asian Pacific Congress of Nephrology (APCN) 2020. Her projects are supported by Grants-in-Aid for Scientific Research from the Japan Society for the Promotion of Science and research grant from Kyowa Kirin Co. Ltd. She is also a councilor/secretary of the Japanese Society of Nephrology (International liaison committee), International Maillard Reaction Society (IMARS, chief editor of IMARS Highlights), and Japanese Maillard Reaction Society (JMARS, IMARS-JMARS liaison committee) and an Associate Editor of "Clinical and Experimental Pharmacology and Physiology" and "Kidney 360 (American Society of Nephrology online journal, First issue from 2020)”, and Editorial board of "Kidney International" and "American Journal of Physiology-Renal Physiology". *Homepage: http://www.todai-ckd.com/
11:55-12:15
Discussion
Room: Coronado Ballroom E
12:15-1:15
Lunch Hosted by Conference for Workshop Participants
AKI Symposium - Plenary 3
Bench to Bedside: Translating Discoveries to Clinical Care
1:15-3:15
Kathleen Liu, MD, PhD, MAS
Kathleen D. Liu, MD, PhD, MAS is a Professor in the Departments of Medicine and Anesthesia, Divisions of Nephrology and Critical Care Medicine at the University of California, San Francisco. Dr. Liu graduated from the University of California, San Francisco and trained as a resident at the Brigham and Womens Hospital in Boston. She trained in nephrology and critical care at the University of California, San Francisco. She is board-certified in both nephrology and critical care. Her research interests include biomarkers of kidney disease, acute kidney injury and acute lung injury.
Mark Okusa, MD
Mark D. Okusa, M.D. is the John C. Buchanan Distinguished Professor of Medicine, Chief, Division of Nephrology and Director, Center for Immunity, Inflammation and Regenerative Medicine at the University of Virginia, Charlottesville, VA. He received his M.D., and internship and residency training at the Medical College of Virginia, Richmond, VA followed by clinical and research nephrology training at Yale University, New Haven, CT. Dr. Okusa joined the faculty at the University of Virginia in 1991 as a clinician investigator combining clinical care, education and research. His clinical and research interest focus on acute kidney injury. He is the principal investigator of several NIH grants including a T32 training grant. He has published over 130 original manuscripts and book chapters. He has served on advisory committees and study sections for the NIH, ASN, AHA, and NKF and as Chair of the Program Committee of the ASN (2011). Dr. Okusa was the Associate Editor of Nephron Physiology, and Kidney International and current member of the editorial boards of the American Journal of Physiology:Renal Physiology, American Journal of Nephrology, Kidney International and Journal of the American Society of Nephrology. Dr. Okusa has been listed in Castle Connallys Americas Top Doctors (2001-2014), member of the American Clinical and Climatological Association and elected Councilor to the American Society of Nephrology in 2012.
1:15-1:35
Stem Cell-derived Extracellular Vesicles in Kidney Repair
Room: Coronado Ballroom E
Vincenzo Cantaluppi, MD
Vincenzo Cantaluppi is Associate Professor of Nephrology at tbe University of Eastern Piedmont “A. Avogadro”, “Maggiore della Carità” University Hospital in Novara, Italy. He is the Director of Nephrology and Kidney Transplantation Unit at the University of Eastern Piedmont. He is an active clinical investigator in the fields of acute kidney injury, renal replacement therapy in intensive care unit, kidney transplantation. His main lines of basic research are focused on acute kidney injury biomarkers and on development of new potential therapeutic strategies for acute kidney injury based on transplantation of stem cells and derived extracellular vesicles.
1:35-1:55
TIMP-2 is a Therapeutic Target in Sepsis-associated AKI
Room: Coronado Ballroom E
John Kellum, MD
John A. Kellum, MD, FACP, MCCM
John A. Kellum, MD, MCCM is Professor of Critical Care Medicine, Medicine, Bioengineering and Clinical and Translational Science, and Vice Chair for Research within the Department of Critical Care Medicine and Director of the Center for Critical Care Nephrology at the University of Pittsburgh.
Dr. Kellum received his medical degree from the Medical College of Ohio in 1984. His postgraduate training includes an internship and residency in Internal Medicine at the University of Rochester, NY, and a Fellowship in Critical Care Medicine at the University of Pittsburgh Medical Center.
Dr. Kellum is actively involved in education, research and administration. Dr. Kellum’s research interests span various aspects of Critical Care Medicine, but center in critical care nephrology, sepsis and multi-organ failure, and clinical epidemiology, including consensus development and research methodology. He has authored more than 250 publications and has won several awards for teaching. He lectures widely and has given more than 300 seminars and invited lectures worldwide related to his research.
1:55-2:15
Pen Enkephalin: Is it the New GFR Marker?
Room: Coronado Ballroom E
Peter Pickkers, MD, PhD
Peter Pickkers is an internist-intensivist and professor of Experimental Intensive Care Medicine. His research focuses on modulation of the innate immune response, sepsis and specific organ dysfunction, among which the kidney.
2:15-2:35
Microbiome in AKI and Kidney Disease
Room: Coronado Ballroom E
Hamid Rabb, MD
Dr. Rabb completed his MD at McGill University, residency in internal medicine at Harbor-UCLA Medical Center, and fellowship in nephrology/leukocyte biology at Massachusetts General Hospital and Harvard University. He has also trained in lung immunology at McGill University. Dr. Rabb is currently Professor and Vice Chairman of Medicine and Medical Director of Kidney Transplantation at Johns Hopkins Hospital in Baltimore. His research is on the immunologic mechanisms of kidney ischemia reperfusion injury, as well deleterious links between kidney and distant organs during acute kidney injury. His research is currently supported by the NIH & NKF.
2:35-2:55
Fibroblast Growth Factor 23 and Klotho in AKI
Room: Coronado Ballroom E
Orson Moe, MD
2:55-3:15
Discussion
Room: Coronado Ballroom E
3:15-3:30
Coffee Break
AKI Symposium - Plenary 4
Controversies in AKI
3:30-5:30
Steven Alexander, MD
Current: Professor of Pediatrics; Chief, Pediatric Nephrology; Medical Director, Pediatric Dialysis and Kidney Transplantation; Stanford University Medical Center and Lucile Packard Children's Hospital at Stanford. Medical Director, Stanford/Packard Center for Translational Research in Medicine; Member, CRRT 2008 Pediatrics Planning Committee.
Training: Baylor College of Medicine/Texas Children's Hospital (Pediatrics; Pediatric Nephrology)
Former Institutions: Oregon Health Sciences Center; University of Texas Southwestern Medical Center
Azra Bihorac, MD, MS, FCCM, FASN
Azra Bihorac leads large multidisciplinary research partnership PrismaP (Precision and Intelligence in Medicine) that brings together experts in the field of predictive modeling, medical informatics and autonomic networks. Her team is developing machine learning and informatics tool for real-time risk stratification and annotation of hospital-acquired complications that would allow management to be tailored to a patients’ “personal clinical profile” using clinical data gathered during routine care.
3:30-3:50
Infection Risk Post AKI: Should We Worry?
Room: Coronado Ballroom E
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Katja Gist, DO, MSc
I am a dual trained pediatric cardiologist and intensivist. I perform all my clinical care in the cardiac intensive care unit, which is both a surgical and medical intensive care unit for children and adults with congenital and acquired heart disease. I provide expertise in critical care nephrology to my colleagues in the cicu. I perform clinical research in multiple areas of critical care nephrology, predominantly focusing on the systemic complications. At Children's Hospital Colorado, I founded the Pediatric Kidney Injury and Disease Stewardship (PKIDS) program with my nephrology colleague (Dr Soranno). Through PKIDS, we have several hospital wide quality improvement initiatives to reduced nephrotoxic acute kidney injury and enhance AKI awareness. PKIDS also provides a forum for education as well as mentorship of trainees.
3:50-4:10
Subphenotypes of AKI: Do We Have Progress for Personalizing Care?
Room: Coronado Ballroom E
Pavan Bhatraju, Assistant Professor
Our laboratory is interested in understanding the epidemiology and pathophysiology of acute kidney injury (AKI) in critically ill patients. AKI, as currently clinically defined, is caused by a heterogeneous set of pathophysiologic processes and is associated with variable outcomes. We have identified AKI sub-phenotypes with different genetic and molecular characteristics, risk of clinical outcomes, and response to therapeutics. Identification of AKI sub-phenotypes could improve risk prognostication and may be useful for predictive enrichment in clinical trials.
4:10-4:30
Does Contrast Induced Nephrotoxicity Exist?
Room: Coronado Ballroom E
Glenn Chertow, MD
Glenn Chertow, MD, MPH, is the Norman S. Coplon/Satellite Healthcare Professor of Medicine and Chief, Division of Nephrology at Stanford University School of Medicine. His research interests are focused on epidemiology, health services research, and clinical trials in acute and chronic kidney disease. Dr. Chertow is involved in research sponsored by the National Institutes of Health and has written numerous papers on end-stage renal disease, acute renal failure, nutrition, mineral metabolism, and the costs and outcomes of dialysis therapy. He is Co-Editor of Brenner and Rector's The Kidney and serves on the editorial boards of the Journal of the American Society of Nephrology (JASN). Dr. Chertow has designed and/or monitored several NIH- and industry-sponsored cohort studies and clinical trials in kidney disease, including CRIC, ATN, FHN, DAC, SPRINT, TREAT, ADVANCE and EVOLVE. In addition to his research and teaching activities, Dr. Chertow has an active clinical practice, focused on inpatient and outpatient nephrology care.
4:30-4:50
Is Tubular Health a Risk Factor For AKI?
Room: Coronado Ballroom E
Alex Bullen, MD
4:50-5:10
Long-term Outcomes After AKI: Do We Know What to Look For?
Room: Coronado Ballroom E
Edward Siew, MD, MSCI
Dr. Edward D. Siew is an Assistant Professor of Medicine at the Vanderbilt University School of Medicine in Nashville, TN within the Division of Nephrology and Hypertension. Dr. Siew received his medical degree at the University of Chicago Pritzker School of Medicine and completed his residency in internal medicine at The University of California, San Francisco. He also completed fellowships in Critical Care Medicine and the University of Pittsburgh School of Medicine and Nephrology at Vanderbilt University School of Medicine. Dr. Siew is also a graduate of the Masters of Science in Clinical Investigation at Vanderbilt whose research program is focused on improving the care of patients with acute kidney injury (AKI). Ongoing projects include using novel biomarkers of injury to refine the diagnosis of AKI and provide better prognostic information, leveraging the electronic health record to better examine healthcare delivery to patients who experience AKI, and improving understanding of the long-term impact of this disease, including identifying mechanisms that contribute to progressive loss of kidney function and cardiovascular disease in this population. Dr. Siew currently also serves as a co-investigator of the NIH-sponsored Assessment and Serial Evaluation of the Subsequent Sequelae of Acute Kidney Injury (ASSESS-AKI) study, a prospective multi-center study examining the long-term natural history of AKI.
5:10-5:30
Discussion
Room: Coronado Ballroom E
5:30pm
AKI Workshop Adjourns
5:30-7:30pm
Reception and Poster Review
For All Conference Attendees
Tuesday, Morning February 25
7:00am
Conference Registration Open
7:00-8:15
ME1 MEET THE EXPERT
How do I Adjust Drugs During RRT
Linda Awdishu, PharmD, MAS
Linda Awdishu earned her Bachelors of Science in Pharmacy from the University of Toronto in 1999, Doctor of Pharmacy from the University of Colorado in 2008 and Masters of Clinical Research from the University of California in 2007. She is an Associate Clinical Professor of Pharmacy and Medicine at UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences. She maintains a clinical practice in the chronic kidney disease program. Her research program is focused on drug induced kidney injury.
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Patrick Murray, MD
Patrick Murray is Professor of Clinical Pharmacology in University College Dublin, and a consultant physician (clinical pharmacologist & nephrologist) at the Mater Misericordiae University Hospital, Dublin, Ireland.
He received his medical education at University College Dublin, Ireland.
Following his internship at the Mater Misericordiae University Hospital in Dublin, he completed a residency in internal medicine at Hennepin County Medical Center in Minneapolis, Minnesota, USA.
He completed fellowship training programs in nephrology, critical care medicine, and clinical pharmacology at the University Of Chicago Hospitals in Chicago, Illinois, USA.
He is board-certified in nephrology, critical care medicine, and clinical pharmacology.
He practiced as an intensivist, nephrologist, and clinical pharmacologist at the University of Chicago Hospitals from 1996–2008, serving as the fellowship training program director in nephrology, also directing the Acute Dialysis Service.
He has a longstanding interest in research and education to improve the prevention, diagnosis, and therapy of acute kidney injury and nephrotoxicity, and the pharmacotherapy of patients with kidney disease. He is a member of several international consensus groups that have produced guidelines for research and practice in the field of acute kidney injury (ADQI, AKIN, KDOQI).
Since 2008, he has been the Professor of Clinical Pharmacology at University College Dublin, and a Consultant in Nephrology & Clinical Pharmacology at the Mater Misericordiae University Hospital. He is Chair of the Mater Misericordiae University Hospital Drugs & Therapeutics Committee. He is the Clinical Director of the UCD-Mater Clinical Research Centre. In 2011, he was appointed Associate Dean for International Affairs in the UCD School of Medicine and Medical Science. In 2012, he was appointed Director of the Dublin Centre for Clinical Research (DCCR) Consortium Network, and also Clinical Director of the Irish Clinical Research Infrastructure Network (ICRIN). From December 2012 until July 2018, he served as the Dean and Head of the School of Medicine at UCD.
7:00-8:15
ME2 MEET THE EXPERT
How do I Manage the Fluid Overloaded Patient?
Stuart Goldstein, MD
Dr. Goldstein serves as Director for the Center for Acute Care Nephrology (CACN) at Cincinnati Children's Hospital Medical Center. The CACN's mission is to coordinate all AKI related clinical, research and outcomes efforts at CCHMC and to function as a nexus for coordinating multi-center pediatric AKI research. Dr. Goldstein is the Founder and Principal Investigator of the Prospective Pediatric AKI Research Group (www.ppaki.org), a 50 center international pediatric acute care nephrology research consortium that will focuses on pediatric AKI epidemiology, interventional trials, device evaluation and genetic studies. Dr. Goldstein is also the program director for the only Pediatric Acute Care Nephrology fellowship in the United States.
Michael Joannidis, Professor, MD
Michael Joannidis, MD. Dr. Joannidis is Professor in Medicine serving as director of the Division of Intensive Care and Emergency Medicine, Dept. General Internal Medicine, Medical University Innsbruck, Austria. He is a certified specialist in Critical Care medicine and Nephrology. His research interests cover several topics of Critical Care Medicine with a major focus on acute renal injury and renal tubular epithelial pathophysiology. He is president of the Austrian Society of General and Medical Intensive Care and Emergency Medicine (OEGIAIN)
BREAKFAST SYMPOSIA
The Breakfast Symposia listed below are hosted by the Conference (RSVP Required)
Selection made during registration
7:00-8:15
A - Imaging Techniques in Critically Ill Patients with Kidney Disease
CME Available
Imaging studies are a key component to manage patients, however are often underutilized in patients with renal dysfunction for fear of harming the kidney. This symposium will discuss the basis for using different imaging techniques in patients with kidney disease to minimize risk and improve diagnosis.
Nick Selby (Moderator)
Kianoush Kashani and Mitch Rosner (Discussants)
Kianoush Kashani, MD
Kianoush Kashani, MD is a consultant in the Division of Nephrology and Hypertension, Division of Pulmonary and Critical Care at Mayo Clinic, Rochester. His academic rank is Professor in Internal Medicine and Assistant Professor in Medical Education. His research interest is acute kidney injury, electrolyte disorders, simulation medicine, and critical care point-of-care ultrasonography.
Mitchell Rosner, MD
Dr. Rosner is currently the Henry B. Mulholland Professor of Medicine at the University of Virginia School of Medicine as well as the Chairman of the Department of Medicine. Dr. Rosner serves on the executive committee of training program directors for the American Society of Nephrology. His research interests include: sodium and water metabolism and acute kidney injury. He is a fellow of the American Society of Nephrology and a fellow of the American College of Physicians
Nick Selby, MD
Dr Selby studied medicine at the University of Nottingham, graduating in 1998, and after completing post-graduate training in the East Midlands was appointed a full-time NHS consultant nephrologist at the Royal Derby Hospital in 2009. In 2015 he was appointed Associate Professor of Nephrology at the University of Nottingham, based in the Centre for Kidney Research and Innovation (www.nottingham.ac.uk/research/groups/renal), Royal Derby Hospital Postgraduate Medical School.
Dr. Selby is a clinical academic with primary interests in Acute Kidney Injury (AKI), Magnetic Resonance Imaging (MRI) of the kidney and the haemodynamic consequences of dialysis. He led the development of one of the first e-alert systems for AKI in the UK and is CI on several investigator-instigated studies in these areas. Since 2011 Dr Selby has been awarded peer reviewed grant funding from MRC, the Health Foundation, Kidney Research UK and British Renal Society. He has published over 60 peer-reviewed articles. Dr Selby has several national AKI roles, including leadership of the AKI Clinical Study Group that sits within the UK Kidney Research Consortium, the co-chair of the UK Renal Imaging Network and programme board of the NHS England ‘Think Kidneys’ programme.
7:00-8:15
B - Therapeutic Challenges in AKI and CKD: Hyperkalemia
CME Available
This symposium will cover the pathophysiology and management of hyperkalemia in critically ill patients using illustrative cases. Are Ace inhibitors nephrotoxic? What are the newer therapeutic drugs available and how should they be used? When and how should RRT be used in these situations?
Glenn Chertow (Moderator)
Qi Qian and Matthieu Legrand (Discussants)
Glenn Chertow, MD
Glenn Chertow, MD, MPH, is the Norman S. Coplon/Satellite Healthcare Professor of Medicine and Chief, Division of Nephrology at Stanford University School of Medicine. His research interests are focused on epidemiology, health services research, and clinical trials in acute and chronic kidney disease. Dr. Chertow is involved in research sponsored by the National Institutes of Health and has written numerous papers on end-stage renal disease, acute renal failure, nutrition, mineral metabolism, and the costs and outcomes of dialysis therapy. He is Co-Editor of Brenner and Rector's The Kidney and serves on the editorial boards of the Journal of the American Society of Nephrology (JASN). Dr. Chertow has designed and/or monitored several NIH- and industry-sponsored cohort studies and clinical trials in kidney disease, including CRIC, ATN, FHN, DAC, SPRINT, TREAT, ADVANCE and EVOLVE. In addition to his research and teaching activities, Dr. Chertow has an active clinical practice, focused on inpatient and outpatient nephrology care.
Matthieu LeGrand, MD
Pr Matthieu Legrand is Professor of Anesthesiology and Critical care medicine. He holds a PhD in physiology. He Works in the Department of anesthesiology, Critical care and burn unit of St-Louis hospital, university Paris Diderot, France. He has carried preclinical and clinical research in the field of critical care medicine with a special interest in critical care nephrology, sepsis and in burn critical care. He has served as a reviewer for several peer-review journals and expert in the field of critical care for several commitees and task forces.
Qi Qian, MD
Dr. Qi Qian is a faculty nephrologist and Professor of Medicine and Professor of Physiology at the Mayo Clinic College of Medicine and Mayo Graduate School, USA. She is the Director of the Mayo Clinic Rochester Nephrology Hospital Practice. She is also an adjunct Professor of Medicine at four top universities in China (Nanjing University School of Medicine in Nanjing, Fourth Military Medical University in Xi’an, Zhejiang University in Hangzhou, and Fudan University, Shanghai, China)
A graduate of the Shanghai 2nd Medical University, Dr. Qian received her post-graduate training in medicine and nephrology at the Albert Einstein College of Medicine, Bronx, New York and was recruited to join the staff at Mayo Clinic upon her graduation from fellowship training in 1999. Dr. Qian's professional focus is on patient care, clinical/translational research and education in the area of renal tubular disorders. In the years of 2000-2008, she conducted basic science research on the renal/vascular pathophysiology through funding from Mayo Clinic Foundation and the National Institutes of Health (NIH-NIDDK). Her expertise in renal and vascular physiology and pathophysiology adds an important dimension to her management of patients with renal tubular diseases.
Dr. Qian also heads the Mayo Clinic Acid-Base Electrolyte Interest Group. She is the principal investigator on a number of studies investigating the effects of electrolyte alterations and renal tubular function. Dr. Qian is an award-winning educator at Mayo Clinic. She has mentored a large number of trainees and is an author and content expert for “AskMayoExpert”, a popular Mayo Clinic web-based medical practice reference for clinicians all over the United States. She currently serves as the president of the Chinese American Society of Nephrology and an ISN Educational Ambassador.
SESSION I: PATIENT CHARACTERISTICS
Plenary 1 MINI-SYMPOSIA
Organ Dysfunction in the Critically Ill Patient: Emerging Concepts
8:20-10:30
Noel Gibney, MB FRCP(C)
Current Position:
Professor, Department of Critical Care Medicine,Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Medical School:
University College Dublin, Ireland
Internal Medicine/Nephrology:
St. Vincents Hospital, Dublin, Ireland
Pulmonary Medicine:
University of Alberta, Edmonton, AB, Canada
Critical Care Medicine:
Harvard University, Cambridge, MA, USA
Interests:
CRRT, Sepsis, Information Technology
Kathleen Liu, MD, PhD, MAS
Kathleen D. Liu, MD, PhD, MAS is a Professor in the Departments of Medicine and Anesthesia, Divisions of Nephrology and Critical Care Medicine at the University of California, San Francisco. Dr. Liu graduated from the University of California, San Francisco and trained as a resident at the Brigham and Womens Hospital in Boston. She trained in nephrology and critical care at the University of California, San Francisco. She is board-certified in both nephrology and critical care. Her research interests include biomarkers of kidney disease, acute kidney injury and acute lung injury.
8:20-8:30
Opening Remarks
Ravindra Mehta, MBBS, MD, DM, FACP
Dr. Mehta is Professor of Medicine in the Division of Nephrology and Associate Chair for Clinical Affairs in the Department of Medicine at the University of California, San Diego (UCSD) where he directs the Clinical nephrology and dialysis programs. He is also the Chair of the International Society of Nephrology Commission on Acute Renal Failure, founding member of the Acute Dialysis Quality Initiative. He received the M.B.B.S. degree (1976) from the Government Medical School in Amritsar, India, and the M.D. (1979) and D.M. (1981) degrees from the Post Graduate Institute of Medical Education and Research in Chandigarh, India. He subsequently completed a nephrology fellowship at the University of Rochester in Rochester New York and obtained his boards in internal medicine (1986) and Nephrology (1988). He has been on the faculty at San Diego since 1988. His reserach interests are in the field of acute renal failure and he has directed several clinical studies in the management of patients with ARF including comparing different dialytic modalities, conducting large multicenter observational studies of ARF with the PICARD group, evaluating different predictive models for outcomes in ARF, investigating the role of cytokine removal by dialysis membranes in sepsis and ARF, and evaluating techniques for determining the amount of excess fluid in dialysis patients.
8:30-8:45
The Renal Response to Brain Injury
Room: Coronado Ballroom
Matthieu LeGrand, MD
Pr Matthieu Legrand is Professor of Anesthesiology and Critical care medicine. He holds a PhD in physiology. He Works in the Department of anesthesiology, Critical care and burn unit of St-Louis hospital, university Paris Diderot, France. He has carried preclinical and clinical research in the field of critical care medicine with a special interest in critical care nephrology, sepsis and in burn critical care. He has served as a reviewer for several peer-review journals and expert in the field of critical care for several commitees and task forces.
8:45-9:00
Endocrine Dysfunction in Critical Illness
Room: Coronado Ballroom
Peter Pickkers, MD, PhD
Peter Pickkers is an internist-intensivist and professor of Experimental Intensive Care Medicine. His research focuses on modulation of the innate immune response, sepsis and specific organ dysfunction, among which the kidney.
9:00-9:15
PAMPS and DAMPS in Septic AKI
Room: Coronado Ballroom
Vincenzo Cantaluppi, MD
Vincenzo Cantaluppi is Associate Professor of Nephrology at tbe University of Eastern Piedmont “A. Avogadro”, “Maggiore della Carità” University Hospital in Novara, Italy. He is the Director of Nephrology and Kidney Transplantation Unit at the University of Eastern Piedmont. He is an active clinical investigator in the fields of acute kidney injury, renal replacement therapy in intensive care unit, kidney transplantation. His main lines of basic research are focused on acute kidney injury biomarkers and on development of new potential therapeutic strategies for acute kidney injury based on transplantation of stem cells and derived extracellular vesicles.
9:15-9:30
Hyperlactatemia: Definitions and Pathophysiology
Room: Coronado Ballroom
Lui Forni, MD
9:30-9:45
Liver Kidney Interactions: Physiology Unravelled
Room: Coronado Ballroom
Andrew Davenport, MD, FRCP
I am currently responsible for the planning and organisation and delivery of dialysis treatments in North Central London, UK. The chronic dialysis program comprises around 170 peritoneal dialysis & 520 hemodialysis patients. Acute renal failure requiring renal support is managed between the renal high dependency ward (for non-ventilated patients)and in the intensive care units. The hospital specialises in liver transplantation, neurosurgery and bone marrow transplantation. More than 150 patients with acute renal failure are treated each year.
9:45-10:00
Precision Medicine in the ICU: Profiling Biofluids
Room: Coronado Ballroom
Eric Hoste, MD, PhD
Eric HOSTE
Training
- Doctor in Medicine, Surgery, and Obstetrics, Ghent University, Belgium 1989.
- Board Certified: Internal Medicine, October 1995.
- Board Certified: Intensive Care Medicine 1997.
- PhD Doctorate in the Medical Sciences, 30th November 2004 titled Acute Renal Failure in Critically Ill Patients.
Working career
- Chief of Clinic, Intensive Care Unit, Ghent University Hospital, Belgium
- Research fellow in Critical Care Medicine, The CRISMA laboratory, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, August-December 2003
Author and co-author of
- 42 publications in international peer reviewed journals
- 5 book chapters
10:00-10:30
SPECIAL LECTURE
Clinical Phenotypes of Sepsis
Room: Coronado Ballroom
John Kellum, MD
John A. Kellum, MD, FACP, MCCM
John A. Kellum, MD, MCCM is Professor of Critical Care Medicine, Medicine, Bioengineering and Clinical and Translational Science, and Vice Chair for Research within the Department of Critical Care Medicine and Director of the Center for Critical Care Nephrology at the University of Pittsburgh.
Dr. Kellum received his medical degree from the Medical College of Ohio in 1984. His postgraduate training includes an internship and residency in Internal Medicine at the University of Rochester, NY, and a Fellowship in Critical Care Medicine at the University of Pittsburgh Medical Center.
Dr. Kellum is actively involved in education, research and administration. Dr. Kellum’s research interests span various aspects of Critical Care Medicine, but center in critical care nephrology, sepsis and multi-organ failure, and clinical epidemiology, including consensus development and research methodology. He has authored more than 250 publications and has won several awards for teaching. He lectures widely and has given more than 300 seminars and invited lectures worldwide related to his research.
10:30-11:00
Coffee Break and Faculty Picture
STANDARD WORKSHOPS
Open to all participants and applicable to physicians, nurses and allied personnel.
Workshop Codes: C= Core workshop, I = Intermediate, A = Advanced, N= Nurses, AP = of interest to nurses and allied personnel.
Standard Workshop Group 1
11:00-12:30
11:00-12:30
A01 Who Should Get a Kidney Biomarker Assessment? (C,N,AP)
Several biomarkers are now available to assess kidney function and damage. Which patients should get these assessments and how should these be applied will be discussed in this case based workshop.
Rajit Basu, MD, MS, FCCM
Dr. Basu is dedicated to improving the recognition, treatment, and outcomes of critically ill children suffering acute kidney injury. As Co-Director of the Center for Acute Care Nephrology at Cincinnati Children's Hospital, Dr. Basu oversees projects in the pediatric intensive care unit investigating AKI prediction by risk stratified optimization of biomarkers (renal angina), biomarker and fluid overload directed renal replacement therapy initiation, and use of the EMR to provide clinical decision support for management of AKI and fluid balance. Prior to arriving at Cincinnati Children's in 2009, Dr. Basu completed his Pediatric Critical Care fellowship and Pediatric residency at Northwestern University in Chicago. Originally from South Bend, Indiana, he is a graduate of Indiana University Medical School and the University of Notre Dame (undergraduate degree in Biochemistry).
Jay Koyner, MD
Dr. Koyner is an Associate Professor of Medicine in the Section of Nephrology at the University of Chicago. He completed his Internal Medicine and Nephrology training at the University of Chicago Medical Center where he currently serves as the medical director of the Inpatient Dialysis Unit and Director of ICU Nephrology. His critical care nephrology research interests have focused on the utilization of plasma and urine biomarkers to improve patient risk stratification and outcomes in the setting of AKI. In addition to biomarkers, other research interests include predictive analytics, AKI following cardiac surgery, CRRT and AKI therapeutics. He has published over 100 peer-reviewed articles and book chapters on AKI and the care of patients in with kidney injury in the ICU.
Alex Zarbock, MD
Dr. Zarbock is a Clinician Scientist and the Director and Chair of the Department of Anesthesiology and Critical Care Medicine, at the University of Münster, Germany. He acquired training at the University of Münster (Anesthesiology and Critical Care Medicine). Dr. Zarbock is supported by the German Research Foundation. His research interests span various aspects of Critical Care Medicine, but center in critical care nephrology (renal replacement therapy), sepsis and organ protection. Dr. Zarbock’s current projects include measures to avoid acute kidney injury after surgery and the timing of renal replacement therapy in critically ill patients with acute kidney injury. He is also author and co-author of over 140 scientific articles and book chapters.
11:00-12:30
B02 Citrate Anticoagulation for CRRT: How to Use it? (C,N,AP)
Regional citrate anticoagulation (RCA) is increasingly utilized for CRRT. Advances in technology have enabled automated citrate anticoagulation. However, concerns remain about its ease of use and application in patients with liver failure and reduced tissue perfusion. This workshop will discuss the best approaches for utilizing RCA for CRRT.
Ian Baldwin, RN, PhD, FACCCN
Professor Ian Baldwin; Introduction
Ian is an experienced speaker and presenter from Melbourne, Australia, where he is an Educator for post registration Intensive Care Nursing at the Austin hospital, and has an association with both RMIT and Deakin University as Adjunct Professor.
Ian has undertaken many research activities in the field of renal support therapies and has presented on many occasions in Australia, Asia, the United States and Europe, and is a recipient of the Vicenza 'Award' from the IRRIV, Italy in 2018.
Ian has completed a Masters and PhD in RRT clinical research, and is a past winner of best paper presentations at the Australian Intensive Care Society meetings. Ian has over 110 publications devoted to CRRT and other research activities in critical care and has authored multiple book chapters for AKI and hemofiltration.
Ian is a reviewer for Australian Critical Care, the American Journal of Kidney Diseases,Intensive Care Medicine,and an Associate Editor for Blood Purification.
Matthieu LeGrand, MD
Pr Matthieu Legrand is Professor of Anesthesiology and Critical care medicine. He holds a PhD in physiology. He Works in the Department of anesthesiology, Critical care and burn unit of St-Louis hospital, university Paris Diderot, France. He has carried preclinical and clinical research in the field of critical care medicine with a special interest in critical care nephrology, sepsis and in burn critical care. He has served as a reviewer for several peer-review journals and expert in the field of critical care for several commitees and task forces.
Ashita Tolwani, MD
Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
11:00-12:30
C03 Assessment of Fluid Responsiveness, Hemodynamic Monitoring and Targets (C,N)
Determining which patient needs fluids, what type and how much are key questions to be addressed in this workshop which will cover the principles and strategies for volume assessment, hemodynamic and microcirculatory monitoring in critically ill patients.
Katja Gist, DO, MSc
I am a dual trained pediatric cardiologist and intensivist. I perform all my clinical care in the cardiac intensive care unit, which is both a surgical and medical intensive care unit for children and adults with congenital and acquired heart disease. I provide expertise in critical care nephrology to my colleagues in the cicu. I perform clinical research in multiple areas of critical care nephrology, predominantly focusing on the systemic complications. At Children's Hospital Colorado, I founded the Pediatric Kidney Injury and Disease Stewardship (PKIDS) program with my nephrology colleague (Dr Soranno). Through PKIDS, we have several hospital wide quality improvement initiatives to reduced nephrotoxic acute kidney injury and enhance AKI awareness. PKIDS also provides a forum for education as well as mentorship of trainees.
Kianoush Kashani, MD
Kianoush Kashani, MD is a consultant in the Division of Nephrology and Hypertension, Division of Pulmonary and Critical Care at Mayo Clinic, Rochester. His academic rank is Professor in Internal Medicine and Assistant Professor in Medical Education. His research interest is acute kidney injury, electrolyte disorders, simulation medicine, and critical care point-of-care ultrasonography.
Andrew Shaw, MB, FRCA, FRCPC, FFI
Dr Shaw is Professor of Anesthesiology and Executive Vice Chair, Dept of Anesthesiology at Vanderbilt University Medical Center, Nashville, TN. He is a Fellow of the Royal College of Anaesthetists (UK) and a Fellow of the American College of Critical Care Medicine. He has practiced cardiothoracic anesthesiology and critical care medicine for more than 20 years in the UK and USA, and has authored 3 major textbooks and more than 130 original papers. His research interests lie in clinical and translational studies of outcomes following cardiothoracic surgery, particularly acute kidney injury after heart surgery, and personalized medicine.
11:00-12:30
D04 Managing Patients with Combined Kidney and Liver Failure (C,N,AP)
Patients with combined liver and kidney failure are difficult to manage. This workshop will discuss the pathophysiology and illustrate best approaches for differential diagnosis and management of these patients.
Andrew Davenport, MD, FRCP
I am currently responsible for the planning and organisation and delivery of dialysis treatments in North Central London, UK. The chronic dialysis program comprises around 170 peritoneal dialysis & 520 hemodialysis patients. Acute renal failure requiring renal support is managed between the renal high dependency ward (for non-ventilated patients)and in the intensive care units. The hospital specialises in liver transplantation, neurosurgery and bone marrow transplantation. More than 150 patients with acute renal failure are treated each year.
Mitra Nadim, MD, FASN
Mitra Nadim is an Associate Professor of Clinical Medicine in the Division of Nephrology and Hypertension at the University of Southern California. She completed her medical school at UCLA, Internal Medicine Residencey at the Beth Israel Hospital in Boston and Nephrology Fellowship at Brigham and Women’s / Massachusetts General Hospital joint program. She is the the renal system chair for the Year 2 Medical School curriculum at Keck School of Medicine and the Director of USC’s Hypertension Center.
Michael Zappitelli, MD, MSc
Michael Zappitelli, MD, MSc practices Pediatric Nephrology, currently Assistant Professor in Pediatrics and Director of the Extracorporeal Blood Therapy and Peritoneal Dialysis Program in Montreal Canada. After training in Pediatric Nephrology and in Epidemiology and Biostatistics at McGill University, Montreal, Canada (2003-2005), he completed a research fellowship in Pediatric Critical Care Nephrology at Texas Children's Hospital, Baylor College of Medicine, Houston, Texas (2005-2007). He has performed research in estimating glomerular filtration rate in children, using serum creatinine and cystatin C-based equations, has published manuscripts on the use of early biomarkers of acute kidney injury in children and on the validation of a pediatric definition for acute kidney injury and has written several book chapters on diagnosis and management of pediatric acute kidney injury. He also performed research in the area of nutritional provision in children treated with continuous renal replacement therapy. Currently, he continues to perform research in early biomarkers of acute kidney injury in children and on epidemiology and definition of pediatric acute kidney injury.
11:00-12:30
E05 Establishing and Maintaining a Performance Improvement Program for RRT (I,N,AP)
NURSES TRACK (E Series)
Although RRT is commonly applies worldwide there are minimal established criteria for monitoring the quality of care delivered. This workshop will discuss how to set up and implement a quality assessment program for RRT based on the recommendations from the ADQI 22 consensus conference.
Ian Baldwin, RN, PhD, FACCCN
Professor Ian Baldwin; Introduction
Ian is an experienced speaker and presenter from Melbourne, Australia, where he is an Educator for post registration Intensive Care Nursing at the Austin hospital, and has an association with both RMIT and Deakin University as Adjunct Professor.
Ian has undertaken many research activities in the field of renal support therapies and has presented on many occasions in Australia, Asia, the United States and Europe, and is a recipient of the Vicenza 'Award' from the IRRIV, Italy in 2018.
Ian has completed a Masters and PhD in RRT clinical research, and is a past winner of best paper presentations at the Australian Intensive Care Society meetings. Ian has over 110 publications devoted to CRRT and other research activities in critical care and has authored multiple book chapters for AKI and hemofiltration.
Ian is a reviewer for Australian Critical Care, the American Journal of Kidney Diseases,Intensive Care Medicine,and an Associate Editor for Blood Purification.
Katrina Eggleston, MSN, RN
Katrina has been working in acute dialysis for over 14 years as a preceptor and charge nurse. She now holds the position of Manager of CRRT, traveling to acute facilities training their staff on CRRT.
Theresa Mottes, MSN, RN,CPNP-AC,CDN
Theresa Mottes has over 20 years of pediatric renal replacement therapy experience is both the critical care setting and the outpatient dialysis setting. She has been involved in research with acute kidney injury, continuous renal replacement therapies and simulation based education for CRRT training. Theresa currently is a nurse practitioner for critical care nephrology. Theresa is very active with ANNA, as the current Pediatric Specialty Practice Network facilitator. She has presented at both national and international conferences.
11:00-12:30
F06 Principles, Applications and Practical Issues of Plasma Exchange (C,N,AP)
Plasma exchange (PE) is increasingly utilized in the ICU with CRRT and other extracorporeal techniques. This workshop will describe the best approaches for applying PE in critically ill patients.
Isagani Marquez, MSN, RN, QIA
Eisei Noiri, MD, PhD, FASN
Eisei NOIRI graduated from Hamamatsu University School of Medicine (HUSM) and received PhD at The University of Tokyo under Prof. Kiyoshi Kurokawa. He spent three years in SUNY Stony Brook and BNL under Prof. Michael Goligorsky. He is one of the chief researchers in Division of Nephrology and head of Department of Hemodialysis and Apheresis in The University of Tokyo Hospital. His research interests are broad from basic sciences in AKI pathophysiology, clinical applicability of biomarkers, epidemiology of CRRT, theoretical consideration to CRRT and apheresis therapy, and more.
Amber Sanchez, MD
Amber P. Sanchez received her M.D. with AOA distinction from the University of Texas Medical School at Houston. Her residency, chief residency, and fellowship were completed at the University of California San Diego (UCSD) where she has been on the faculty since 2010. Dr. Sanchez is board certified in Internal Medicine and Nephrology and has a special interest in therapeutic apheresis and glomerulonephritis. She has served as the Associate Medical Director for the UCSD Therapeutic Apheresis Program since 2010. She is the co-creator and course director for UCSD's Essentials and Advances in Apheresis Therapies conference that is held in San Diego annually.
LUNCH SYMPOSIA
Lunch Symposia Hosted by Conference (RSVP Required)
Selection made during registration
12:30-2:00
Lunch Symposium T1. Renal Functional Measurement: Emerging Techniques and Results
CME Available
Moderators: Lewington and Bihorac
Renal functional assessment is currently based on measured or estimated creatinine clearances that do not reflect the overall state of kidney health. New techniques for measuring real time GFR, plasma volume and tubular function are now emerging and will change our approach for patient management. This symposium will discuss the emerging techniques and their applications
Non-invasive GFR Measurements - TBD
Measuring Tubular Health - Macedo
Renal Functional Reserve - Ronco
Azra Bihorac, MD, MS, FCCM, FASN
Azra Bihorac leads large multidisciplinary research partnership PrismaP (Precision and Intelligence in Medicine) that brings together experts in the field of predictive modeling, medical informatics and autonomic networks. Her team is developing machine learning and informatics tool for real-time risk stratification and annotation of hospital-acquired complications that would allow management to be tailored to a patients’ “personal clinical profile” using clinical data gathered during routine care.
Andrew Lewington, MD
Dr Andrew Lewington studied medicine as an undergraduate in London before pursuing a career in renal medicine. He studied in Leicester UK and Washington University USA where he worked in Mark Hammermann's laboratory investigating the molecular mechanisms underlying ischaemic acute kidney injury.Dr Lewington was appointed consultant renal physician/honorary senior lecturer at Leeds Teaching Hospitals in 2004. He works as an NHS clinician providing a specialist renal opinion on acutely ill patients on the ICU across Leeds. He was an expert adviser on the UK NCEPOD adding insult to injury AKI study, working from his position on the Renal Association executive committee to improve the care that patients who develop AKI receive. He is the lead author of the 5th Renal Association AKI clinical practice guidelines. During his time in Leeds he has developed collaborative research with an internationally recognised proteomics group. He currently has a nephrology fellow investigating potential proteomic biomarkers of kidney dysfunction in the early phase following kidney transplantation. He is Clinical Sub Dean for the Leeds Teaching Hospitals and is heavily involved in the delivery of undergraduate medical education at the University of Leeds.
Etienne Macedo, MD, PhD, FASN
Etienne Macedo graduated from the University of Sao Paulo (USP) in Sao Paulo, Brazil. She completed her residency and fellowship through the USP Hospital das Clinicas, and her post-doctorate at the University of California, San Diego, where she continues to work as a clinician and researcher in AKI.
Claudio Ronco, MD
Actual Position:
Dr. Claudio Ronco
Director
Department of Nephrology
St. Bortolo Hospital
Viale Rodolfi 16
I-36100 Vicenza
Italy
Name: Claudio Ronco
Date of birth: July 12, 1951
Education: High School Diploma at Vicenza Classic Lyceum A.Pigafetta in 1970 with the score: 45/60. Dr. Ronco Graduated in Medicine at University of Padua in 1976 with the score 110/110 and merit debating an experimental thesis on title Aspects of the Nitrogen metabolism in the nephrotic syndrome.
From 1973 to 1976 has been intern at Institute of Clinical Internal Medicine I^ of the University of Padua, directed by Prof. E. Fiaschi, in the Nephrology Department II, under the supervision of the Prof. G. Maschio.
Postgraduate training: From July 1976 to November 1977 he has been internal resident at the Division of Internal Medicine of the St. Bortolo Hospital in Vicenza, directed by Prof. D. Cor.
In 1979 he has achieved the Specialization Diploma on Medical Nephrology at The postgraduate school of internal medicine of the University of Padua, with the score 70/70 debating a thesis on the new methodologies for the measurement of the urinary bicarbonate
In 1989 he has achieved the Diploma of Specialization in Pediatric Nephrology at University of Naples.
1982: Visiting Fellow at the Mount Sinai Hospital in New York, Department of Internal medicine, Nephrology Division, for four months. He carried out studies on hemofiltration and glomerular filtration with J.P. Bosh, S. Glabman and M. Levitt.
1984: Visiting Physician at the Mount Sinai Hospital In New York for two weeks and at VA Hospital in Los Angeles for two weeks.
1985: Visiting professor at the Nephrology Division of the George Washington University Hospital, Washington DC, and NIH at National Naval Medical Center of Bethesda for three months.
1988: Visiting professor at the Renal and Hypertension Division of George Washington University for three months.
1991: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
1995: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
Teaching acitivity and Academic Qualifications: From 1978 to 1984 he has been in charge of the teaching program of Nephrology and Dialysis at Professional Nursing School in Vicenza.
During the academic years 1989-01 he has been in charge of teaching Dialytic therapy at Specialization School in Medical Nephrology of Padua University where he holds a post of Professor of Nephrology in charge of the teaching program concerning Hemodialysis and renal replacement therapies in critically ill patients.
October 1999-December 2000: Professor of Medicine at Albert Einstein College of Medicine and Director of the Renal laboratory at the Beth israel Medical Center in New York.
In the last ten years Professor Ronco was asked to deliver lectures and seminars in several Universities.
He has delivered in meetings and seminars more than 300 lectures and presentations.
In 1982 he introduced in Italy the use of continuous hemofiltration and in 1986 he published the first series of neonates treated with arteriovenous hemofiltration.
In 1985 He contributed to the introduction in Europe of high flux dialysis and derived therapies. He also established the dangerous effect of backfiltration in a contaminated dialysis fluid condition.
He has conducted a series of clinical and experimental researches in the following fields:
- Kinetics of fluid and solute removal in peritoneal dialysis and hemodialysis
- Treatment of Acute renal failure with intermittent and continuous therapies
- Renal replacement therapy in the neonate
- Development of new treatment modalities for acute and chronic renal failure.
- Studies on biomaterials
- Studies on glomerular filtration in humans and renal functional reserve
- Renal physiology in pregnancy
- Hydraulics and flow dynamics in the extracorporeal circulation
- Adequacy of dialysis
- Acid-Base Balance in uremia and dialysis
- Acute renal failure and Critical Care Nephrology
Professional employement and Hospital appointments:
Assistant of clinical nephrology from 1977 to 1984 at Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Associate of clinical nephrology from 1984 at Department of Nephrology , St. Bortolo Hospital, Vicenza, Italy.
From 1984 he is director of the hemodialysis and peritoneal dialysis center of the Department of Nephrology at St. Bortolo Hospital, Vicenza, Italy.
From October 25, 1999 to December 1st 2000 Dr. Ronco has been Director of the research laboratory of Hemodialysis at the Beth Israel Medical center of New York and Visiting Professor of Medicine at the Albert Einstein College of Medicine of new York
Today Dr. Ronco is director of the Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Board certification: In 1989 he has achieved in Rome, the National License for Nephrology Chair and Directional Functions, with the score 94/100.
Professional Society Membership: He is mamber of the council of several scientific societies and he is editor in chief of the international journal of artificial organs and contributions to nephrology.
Awards and honors:
1983 Schwartz Award, for the best paper of the year at St. Bortolo Hospital.
1984 G.F. Volpato Grant for the best research project on acute renal failure in Italy
1989 Best paper Prize at the Italian Society of nephrology meeting.
1991 ESAO RESEARCH AWARD for the best paper presented at the European Society for Artificial Organs.
1996 Arturo Borsatti Award of Padova University as a best nephrologist of the year.
2004 Lifetime achievement award
Other professional activities: He has organized several congresses and meetings in the area of nephrology and Intensive care from 1982 to today.
He is member of several advisory groups for clinical trials and dialysis research.
Lectures and publications: Dr. Ronco has coauthored 560 papers, 36 book chapters, 26 books, 7 monographic journal issues and has delivered more than 300 lectures in international meetings and universities. His personal impact factor calculated at december 2002 is 391.
12:30-2:00
Lunch Symposium T2. Personalized Management of Shock: How to use Biomarkers, Vasopresssors and Fluids?
CME Available
Moderators: Bagshaw and Pickkers
There is increasing evidence that different patient respond differently to fluids and vasopressor management for shock. This symposium will discuss how best we may identify phenotypes to personalize fluid type (colloids and crystalloids and blood products) and volume and vasopressor management in shock patients to improve outcomes.
Biomarkers in Shock: Can They Identify Phenotypes? - Liu
Response to Vasopressors: Can We Personalize? - Forni
Which Fluids Should We Use? - Kellum
Sean Bagshaw, MD, MSc, FRCPC
Dr. Bagshaw is a Clinician Scientist and Assistant Professor in the Division of Critical Care Medicine, at the University of Alberta in Edmonton, Alberta, Canada. He acquired training at the University of Calgary (Internal Medicine, Critical Care Medicine, Masters of Science Epidemiology) prior to completing a critical care nephrology fellowship in the Department of Intensive Care Medicine, at the Austin Hospital in Melbourne, Australia.
Dr. Bagshaw is supported by a Canada Research Chair in Critical Care Nephrology and a Clinical Investigator Award from Alberta Innovates - Health Solutions. Dr. Bagshaw's main research interests have focused on the clinical, epidemiological and translational issues related to acute kidney injury and the application of extracorporeal blood purification in critically ill patients. Dr. Bagshaw's current projects include diuretic therapy in early acute kidney injury and factors related with the initiation of renal support in critically ill patients. He has published over 100 peer-reviewed papers, numerous book chapters, and peer-reviewed for over 20 medical journals.
Dr. Bagshaw is a member of several organizations including the Canadian Critical Care Society, Canadian Critical Care Trials Group, Australia New Zealand Intensive Care Society, and the Acute Kidney Injury Network, and the Acute Dialysis Quality Initiative.
Lui Forni, MD
John Kellum, MD
John A. Kellum, MD, FACP, MCCM
John A. Kellum, MD, MCCM is Professor of Critical Care Medicine, Medicine, Bioengineering and Clinical and Translational Science, and Vice Chair for Research within the Department of Critical Care Medicine and Director of the Center for Critical Care Nephrology at the University of Pittsburgh.
Dr. Kellum received his medical degree from the Medical College of Ohio in 1984. His postgraduate training includes an internship and residency in Internal Medicine at the University of Rochester, NY, and a Fellowship in Critical Care Medicine at the University of Pittsburgh Medical Center.
Dr. Kellum is actively involved in education, research and administration. Dr. Kellum’s research interests span various aspects of Critical Care Medicine, but center in critical care nephrology, sepsis and multi-organ failure, and clinical epidemiology, including consensus development and research methodology. He has authored more than 250 publications and has won several awards for teaching. He lectures widely and has given more than 300 seminars and invited lectures worldwide related to his research.
Kathleen Liu, MD, PhD, MAS
Kathleen D. Liu, MD, PhD, MAS is a Professor in the Departments of Medicine and Anesthesia, Divisions of Nephrology and Critical Care Medicine at the University of California, San Francisco. Dr. Liu graduated from the University of California, San Francisco and trained as a resident at the Brigham and Womens Hospital in Boston. She trained in nephrology and critical care at the University of California, San Francisco. She is board-certified in both nephrology and critical care. Her research interests include biomarkers of kidney disease, acute kidney injury and acute lung injury.
Peter Pickkers, MD, PhD
Peter Pickkers is an internist-intensivist and professor of Experimental Intensive Care Medicine. His research focuses on modulation of the innate immune response, sepsis and specific organ dysfunction, among which the kidney.
12:30-2:00
Lunch Symposium T3. Extracorporeal Organ Support (ECOS) for Multi Organ Failure
CME Available
Moderators: Ricci and Nadim
ECOS techniques have evolved to providing novel methods for blood purification and achieving homeostasis. This symposium will cover the recent advances in this field and discuss how best to utilize these techniques in different settings.
Bioartificial and Extracorporeal Support for Acute on Chronic Liver Failure - Davenport
Techniques for Sepsis and Septic Shock - Honore
ECMO and ECCOR for the Failing Lung - Willie
Andrew Davenport, MD, FRCP
I am currently responsible for the planning and organisation and delivery of dialysis treatments in North Central London, UK. The chronic dialysis program comprises around 170 peritoneal dialysis & 520 hemodialysis patients. Acute renal failure requiring renal support is managed between the renal high dependency ward (for non-ventilated patients)and in the intensive care units. The hospital specialises in liver transplantation, neurosurgery and bone marrow transplantation. More than 150 patients with acute renal failure are treated each year.
Patrick Honore, MD, PhD
Prof Patrick Honoré, MD,PhD,FCCM
Intensivist-Nephrologist
Co-Director of ICU Dept and Prof of Medicine
Coordinator of Critical Care Research Department
Centre Hospitalier Universitaire Brugmann/Brugmann University Hospital
B-1020 Brussels (Laeken ) BELGIUM
Patrick Honoré, graduated from Louvain Medical School as MD (1988), Specialist in Internal Medicine (1993), Intensive Care Specialist (1994) and Nephrologist (1995). During his internship, he completed more than 2 1/2 years specialisation in Nephrology and Dialysis. For almost 5 years, he received ICU training abroad (United Kingdom, Australia and USA). Pr Honoré is Board member of the Belgian Intensive Care Society and closely involved in the Nephrology section of the European Society of Intensive Care Medicine. He is also a distinguished member or consultant of many scientific committees and decision-making organizations dedicated to diagnosis, treatment, and research in the field of acute kidney injury in the critically ill. Pr Honoré authored or co-authored more than 228 peer-reviewed papers ,more than 600 abstracts and more than 75 book chapters . He was also editor of three books dedicated to Critical Care Nephrology.He has been invited as a speaker at more than 650 national and international conferences in almost 100 different countries. He acts as reviewer for more than 45 international journals, including top-ranking journals in the field of critical care medicine and nephrology. He is a member of the editorial board of several 25 high-standard journals. He is also Editor-In-Chief of the Journal of Translational Internal Medicine (open access) since 2013, editor-in-chief of Journal of Translational Critical Care Medicine & Journal of Translational Kidney Research since 2015 (open access too).He is also appointed as section editor for Renal in Annals of Intensive Care starting from February 2016.Since 2009, he fulltime fulfils the position of Head of Clinics in the Intensive Care department of the University Hospital, Vrije Universiteit Brussels (VUB) and became Clinical Tutor and Senior Lecturer at the VUB Faculty of Medicine.Since 2012, he fulfils the position of Full Professor at the VUB Faculty of Medicine. In the ICU department, he leads the Critical Care Nephrology Platform which incorporates intensivists, nephrologists and nurses dedicated to daily education, research and treatment of acute kidney injury. In particular, he directs and organizes continuous renal replacement therapy on a 24/24; 7/7 on-call basis.He has also start a CRRT program using citrate dedicated to small children (less than 10 kg) in the UZB -PICU since 2013.Since January 2018, he is holding the position of Co-Director of ICU Department , ICU Research Director, Prof of Medicine at CHU-Brugmann University Hospital
Mitra Nadim, MD, FASN
Mitra Nadim is an Associate Professor of Clinical Medicine in the Division of Nephrology and Hypertension at the University of Southern California. She completed her medical school at UCLA, Internal Medicine Residencey at the Beth Israel Hospital in Boston and Nephrology Fellowship at Brigham and Women’s / Massachusetts General Hospital joint program. She is the the renal system chair for the Year 2 Medical School curriculum at Keck School of Medicine and the Director of USC’s Hypertension Center.
Zaccaria Ricci, MD
Education and training:
Graduation in Medicine on September 1997 at University of “La Sapienza” of Rome, Italy. Specialization in Anesthesiology and Intensive Care on October 2001 at University of “La Sapienza” of Rome, Italy.
Professional experience:
Zaccaria Ricci matured experience in critical care during his period from 2001 to 2006 as a staff clinician in the Intensive Care Unit of the Policlinico Umberto I at the University “La Sapienza” of Rome, Italy. His areas of interest included pharmacological strategies and renal replacement therapies for critically ill patients with acute kidney injury.
His interest and expertise on extracorporeal therapies and blood purification developed in collaboration with the Department of Nephrology Dialysis and Transplantation, Vicenza, Italy, directed by professor Claudio Ronco. In particular, he has focused its main interest in Renal Replacement Dose Delivery and Information Technology applied to new generation machines for acute dialysis. He had the privilege of co-conducting the alpha trials of the Prismaflex and the Carpediem machines.
Since 2006 he is a staff anesthesiologist of the Department of Pediatric Cardiac Surgery at Bambino Gesù Hospital. His work has been devoted to the care of pediatric renal dysfunction and hemodynamic monitoring in the perioperative care of children with congenital heart diseases.
He is author and coauthor of about 200 original articles, reviews and book chapters in the field acute kidney injury diagnosis and therapy and pediatric critical care. He is currently collaborating as a peer reviewer with more than 10 indexed journals in the area of Critical Care and Nephrology. Since October 2009 he is an Associated Faculty Member of Pediatric Critical Care Medicine and in the Editorial Board of the journal Blood Purification. Since October 2013 he is an Associate Editor of the journal BMC Anesthesiology.
Keith Wille, MD
Keith Wille, MD, MSPH is currently a Professor of Medicine at the University of Alabama at Birmingham (UAB). Dr. Wille completed fellowship training in Pulmonary and Critical Care Medicine at UAB and joined the faculty in 2000. His clinical interests are in critical care medicine, extracorporeal support technologies, and cardiothoracic transplantation. He received an MSPH degree in clinical epidemiology from the UAB School of Public Health in 2013 and is currently pursuing a degree in Healthcare Quality and Safety. He is Medical Director of the UAB Adult ECMO and Advanced Lung Diseases Programs and organizes the UAB Extracorporeal Life Support Symposium.
12:30-2:00
Lunch Symposium T4. Improving Care for Patients After Hospitalization for AKI
CME Available
Moderators: Madero and Wu
AKI is a complex disease that requires multidisciplinary interventions however most patients who are hospitalized with an episode of AKI do not have systematic follow up or targeted interventions to improve recovery and mitigate the effects of the disease. This symposium will provide guidance on patient centered approaches to improve the management and outcomes of patients with AKI.
Intermediate Outcomes After AKI: What Should We Focus On? - Siew
Identifying Target Populations for Interventions Post AKI: Do We Know How? - Selby
Following Patients in Clinic Post AKI: How Can We Improve? - Wald
Magdalena Madero, MD
Magdalena Madero, MD, is the Chief of Nephrology at the Instituto Nacional de Cardiología in Mexico City. She was trained in Internal Medicine at St Elisabeth’s Medical Center in Boston, MA, and then underwent her nephrology training at Tufts Medical Center also in Boston, MA. She went back to Mexico City in 2007 where she joined the nephrology staff at Instituto Nacional de Cardilogía and became the Head of the Nephrology Division in 2011.
Dr. Madero's research interests include CKD complications and outcomes in addition to the metabolic and renal effects of fructose and uric acid and more recently is interested in CKD of unknown origin. As part of her educational activities she runs one of the largest renal fellowship programs in the country (affiliated to the main National Mexican University [UNAM]) in addition to teaching the nephrology course at the undergraduate Panamerican University medical school. She is the past president of Mexican Institute of Renal Research (IMIN) and currently acts as the International Editor for the American Journal of Kidney Diseases. She has recently joined the KDIGO Executive Committee.
Nick Selby, MD
Dr Selby studied medicine at the University of Nottingham, graduating in 1998, and after completing post-graduate training in the East Midlands was appointed a full-time NHS consultant nephrologist at the Royal Derby Hospital in 2009. In 2015 he was appointed Associate Professor of Nephrology at the University of Nottingham, based in the Centre for Kidney Research and Innovation (www.nottingham.ac.uk/research/groups/renal), Royal Derby Hospital Postgraduate Medical School.
Dr. Selby is a clinical academic with primary interests in Acute Kidney Injury (AKI), Magnetic Resonance Imaging (MRI) of the kidney and the haemodynamic consequences of dialysis. He led the development of one of the first e-alert systems for AKI in the UK and is CI on several investigator-instigated studies in these areas. Since 2011 Dr Selby has been awarded peer reviewed grant funding from MRC, the Health Foundation, Kidney Research UK and British Renal Society. He has published over 60 peer-reviewed articles. Dr Selby has several national AKI roles, including leadership of the AKI Clinical Study Group that sits within the UK Kidney Research Consortium, the co-chair of the UK Renal Imaging Network and programme board of the NHS England ‘Think Kidneys’ programme.
Edward Siew, MD, MSCI
Dr. Edward D. Siew is an Assistant Professor of Medicine at the Vanderbilt University School of Medicine in Nashville, TN within the Division of Nephrology and Hypertension. Dr. Siew received his medical degree at the University of Chicago Pritzker School of Medicine and completed his residency in internal medicine at The University of California, San Francisco. He also completed fellowships in Critical Care Medicine and the University of Pittsburgh School of Medicine and Nephrology at Vanderbilt University School of Medicine. Dr. Siew is also a graduate of the Masters of Science in Clinical Investigation at Vanderbilt whose research program is focused on improving the care of patients with acute kidney injury (AKI). Ongoing projects include using novel biomarkers of injury to refine the diagnosis of AKI and provide better prognostic information, leveraging the electronic health record to better examine healthcare delivery to patients who experience AKI, and improving understanding of the long-term impact of this disease, including identifying mechanisms that contribute to progressive loss of kidney function and cardiovascular disease in this population. Dr. Siew currently also serves as a co-investigator of the NIH-sponsored Assessment and Serial Evaluation of the Subsequent Sequelae of Acute Kidney Injury (ASSESS-AKI) study, a prospective multi-center study examining the long-term natural history of AKI.
Ron Wald, MD
Ron Wald is a nephrologist at St. Michael's Hospital in Toronto where he also serves as the Medical Director of the hospital's Hemodialysis Program. He is an Associate Professor of Medicine at the University of Toronto. His primary research interest is in critical care nephrology and he has been involved in several clinical trials in this area. He is currently co-leading an international randomized controlled trial on the timing of renal replacement therapy in acute kidney injury. Ron's other interests are volume optimization in patients with AKI and the post-discharge care provided to AKI survivors.
Vincent Wu, MD, PhD
Vin-Cent actively involved in the analysis of a database of acute kidney injury in the National Taiwan University Study Group on Acute Renal Failure (NSARF) and Consortium for Acute Kidney Injury and Renal Diseases (CAKs) strive to advance high-quality care in acute kidney injury (AKI) and aspires to plunge the worldwide increasing prevalence of chronic kidney disease (CKD) from the perspective of AKI-CKD transition.
12:30-2:00
Lunch Symposium I1. Additional Industry Session Offered (Non-CME)
TBA
Tuesday, Afternoon, February 25
Standard Workshop Group 2
2:00-3:30
2:00-3:30
A07 Can Kidney Biomarkers Help Timely Interventions and Prognostication? (C,N,AP)
Clinicians need to determine when a specific intervention is needed and what is the likelihood of modifying the disease course. This workshop will discuss how novel renal biomarkers can be leveraged to guide specific interventions in patients with AKI in different settings.
Rajit Basu, MD, MS, FCCM
Dr. Basu is dedicated to improving the recognition, treatment, and outcomes of critically ill children suffering acute kidney injury. As Co-Director of the Center for Acute Care Nephrology at Cincinnati Children's Hospital, Dr. Basu oversees projects in the pediatric intensive care unit investigating AKI prediction by risk stratified optimization of biomarkers (renal angina), biomarker and fluid overload directed renal replacement therapy initiation, and use of the EMR to provide clinical decision support for management of AKI and fluid balance. Prior to arriving at Cincinnati Children's in 2009, Dr. Basu completed his Pediatric Critical Care fellowship and Pediatric residency at Northwestern University in Chicago. Originally from South Bend, Indiana, he is a graduate of Indiana University Medical School and the University of Notre Dame (undergraduate degree in Biochemistry).
Jay Koyner, MD
Dr. Koyner is an Associate Professor of Medicine in the Section of Nephrology at the University of Chicago. He completed his Internal Medicine and Nephrology training at the University of Chicago Medical Center where he currently serves as the medical director of the Inpatient Dialysis Unit and Director of ICU Nephrology. His critical care nephrology research interests have focused on the utilization of plasma and urine biomarkers to improve patient risk stratification and outcomes in the setting of AKI. In addition to biomarkers, other research interests include predictive analytics, AKI following cardiac surgery, CRRT and AKI therapeutics. He has published over 100 peer-reviewed articles and book chapters on AKI and the care of patients in with kidney injury in the ICU.
Alex Zarbock, MD
Dr. Zarbock is a Clinician Scientist and the Director and Chair of the Department of Anesthesiology and Critical Care Medicine, at the University of Münster, Germany. He acquired training at the University of Münster (Anesthesiology and Critical Care Medicine). Dr. Zarbock is supported by the German Research Foundation. His research interests span various aspects of Critical Care Medicine, but center in critical care nephrology (renal replacement therapy), sepsis and organ protection. Dr. Zarbock’s current projects include measures to avoid acute kidney injury after surgery and the timing of renal replacement therapy in critically ill patients with acute kidney injury. He is also author and co-author of over 140 scientific articles and book chapters.
2:00-3:30
B08 Can We Achieve Precision Solute Control with CRRT? (I,N,AP)
CRRT techniques have evolved with availability of new technology to customize dialysis delivery. This interactive case based workshop will discuss how to apply the technology for dose adjustments, monitoring for adequacy, modality selection and transitions in CRRT.
Rolando Claure-Del Granado, MD, FASN
Rolando Claure-Del Granado received his medical degree from Universidad del Valle, School of Medicine, Cochabamba-Bolivia in 1999. His postgraduate training included a residency in Internal Medicine and a Fellowship in Nephrology at the Instituto Nacional de Ciencias Medicas y Nutricion "Salvador Zubiran" (U.N.A.M), Mexico city, Mexico. He was a Research Fellow at the Medicine Department - Division of Nephrology of the University of California San Diego, from 2009 to 2011. Following his fellowship he joined the faculty of Universidad Mayor de San Simon, School of Medicine in Cochabamba - Bolivia as a Professor of Medicine.
He is a Clinical Research Investigator at the Biomedical Research Institute (IIBISMED) of the Universidad Mayor de San Simon School of Medicine in Cochabamba - Bolivia.
He also is the Head of the Division of Nephrology, Dialysis and Transplantation of Hospital Obrero #2 - C.N.S. in Cochabamba - Bolivia.
He is one of the co-Chairs of the Acute Kidney Injury Committee of the Latin-American Society of Nephrology and Hypertension (SLANH). He is a member of the ISN Latin American Regional Board.
He is an active member of the ISN Social Media Task Force (@ISNeducation)
Dr. Claure-Del Granado's research interests include extracorporeal therapies for AKI, the assessment of acid-base metabolic disorders, biomarkers in AKI, and the use of social medial in education.
Claudio Ronco, MD
Actual Position:
Dr. Claudio Ronco
Director
Department of Nephrology
St. Bortolo Hospital
Viale Rodolfi 16
I-36100 Vicenza
Italy
Name: Claudio Ronco
Date of birth: July 12, 1951
Education: High School Diploma at Vicenza Classic Lyceum A.Pigafetta in 1970 with the score: 45/60. Dr. Ronco Graduated in Medicine at University of Padua in 1976 with the score 110/110 and merit debating an experimental thesis on title Aspects of the Nitrogen metabolism in the nephrotic syndrome.
From 1973 to 1976 has been intern at Institute of Clinical Internal Medicine I^ of the University of Padua, directed by Prof. E. Fiaschi, in the Nephrology Department II, under the supervision of the Prof. G. Maschio.
Postgraduate training: From July 1976 to November 1977 he has been internal resident at the Division of Internal Medicine of the St. Bortolo Hospital in Vicenza, directed by Prof. D. Cor.
In 1979 he has achieved the Specialization Diploma on Medical Nephrology at The postgraduate school of internal medicine of the University of Padua, with the score 70/70 debating a thesis on the new methodologies for the measurement of the urinary bicarbonate
In 1989 he has achieved the Diploma of Specialization in Pediatric Nephrology at University of Naples.
1982: Visiting Fellow at the Mount Sinai Hospital in New York, Department of Internal medicine, Nephrology Division, for four months. He carried out studies on hemofiltration and glomerular filtration with J.P. Bosh, S. Glabman and M. Levitt.
1984: Visiting Physician at the Mount Sinai Hospital In New York for two weeks and at VA Hospital in Los Angeles for two weeks.
1985: Visiting professor at the Nephrology Division of the George Washington University Hospital, Washington DC, and NIH at National Naval Medical Center of Bethesda for three months.
1988: Visiting professor at the Renal and Hypertension Division of George Washington University for three months.
1991: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
1995: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
Teaching acitivity and Academic Qualifications: From 1978 to 1984 he has been in charge of the teaching program of Nephrology and Dialysis at Professional Nursing School in Vicenza.
During the academic years 1989-01 he has been in charge of teaching Dialytic therapy at Specialization School in Medical Nephrology of Padua University where he holds a post of Professor of Nephrology in charge of the teaching program concerning Hemodialysis and renal replacement therapies in critically ill patients.
October 1999-December 2000: Professor of Medicine at Albert Einstein College of Medicine and Director of the Renal laboratory at the Beth israel Medical Center in New York.
In the last ten years Professor Ronco was asked to deliver lectures and seminars in several Universities.
He has delivered in meetings and seminars more than 300 lectures and presentations.
In 1982 he introduced in Italy the use of continuous hemofiltration and in 1986 he published the first series of neonates treated with arteriovenous hemofiltration.
In 1985 He contributed to the introduction in Europe of high flux dialysis and derived therapies. He also established the dangerous effect of backfiltration in a contaminated dialysis fluid condition.
He has conducted a series of clinical and experimental researches in the following fields:
- Kinetics of fluid and solute removal in peritoneal dialysis and hemodialysis
- Treatment of Acute renal failure with intermittent and continuous therapies
- Renal replacement therapy in the neonate
- Development of new treatment modalities for acute and chronic renal failure.
- Studies on biomaterials
- Studies on glomerular filtration in humans and renal functional reserve
- Renal physiology in pregnancy
- Hydraulics and flow dynamics in the extracorporeal circulation
- Adequacy of dialysis
- Acid-Base Balance in uremia and dialysis
- Acute renal failure and Critical Care Nephrology
Professional employement and Hospital appointments:
Assistant of clinical nephrology from 1977 to 1984 at Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Associate of clinical nephrology from 1984 at Department of Nephrology , St. Bortolo Hospital, Vicenza, Italy.
From 1984 he is director of the hemodialysis and peritoneal dialysis center of the Department of Nephrology at St. Bortolo Hospital, Vicenza, Italy.
From October 25, 1999 to December 1st 2000 Dr. Ronco has been Director of the research laboratory of Hemodialysis at the Beth Israel Medical center of New York and Visiting Professor of Medicine at the Albert Einstein College of Medicine of new York
Today Dr. Ronco is director of the Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Board certification: In 1989 he has achieved in Rome, the National License for Nephrology Chair and Directional Functions, with the score 94/100.
Professional Society Membership: He is mamber of the council of several scientific societies and he is editor in chief of the international journal of artificial organs and contributions to nephrology.
Awards and honors:
1983 Schwartz Award, for the best paper of the year at St. Bortolo Hospital.
1984 G.F. Volpato Grant for the best research project on acute renal failure in Italy
1989 Best paper Prize at the Italian Society of nephrology meeting.
1991 ESAO RESEARCH AWARD for the best paper presented at the European Society for Artificial Organs.
1996 Arturo Borsatti Award of Padova University as a best nephrologist of the year.
2004 Lifetime achievement award
Other professional activities: He has organized several congresses and meetings in the area of nephrology and Intensive care from 1982 to today.
He is member of several advisory groups for clinical trials and dialysis research.
Lectures and publications: Dr. Ronco has coauthored 560 papers, 36 book chapters, 26 books, 7 monographic journal issues and has delivered more than 300 lectures in international meetings and universities. His personal impact factor calculated at december 2002 is 391.
David Selewski, MD
I am an Assistant Professor in the Department of Pediatrics within the Division of Nephrology at the University of Michigan. I received my training in pediatrics and pediatric nephrology at the University of Michigan. My clinical and research interests include pediatric critical care nephrology including pediatric & neonatal acute kidney injury, fluid overload, and continuous renal replacement therapy.
2:00-3:30
C09 Starting, Transitioning and Stopping RRT for AKI: Science and Art (A)
One of the most vexing issues for clinicians is determining when to initiate RRT in critically ill patients, when and how to transition modalities and when it can be stopped. This workshop will use case studies to explore various approaches and establish the principles for clinical decisions for renal support.
Etienne Macedo, MD, PhD, FASN
Etienne Macedo graduated from the University of Sao Paulo (USP) in Sao Paulo, Brazil. She completed her residency and fellowship through the USP Hospital das Clinicas, and her post-doctorate at the University of California, San Diego, where she continues to work as a clinician and researcher in AKI.
Ravindra Mehta, MBBS, MD, DM, FACP
Dr. Mehta is Professor of Medicine in the Division of Nephrology and Associate Chair for Clinical Affairs in the Department of Medicine at the University of California, San Diego (UCSD) where he directs the Clinical nephrology and dialysis programs. He is also the Chair of the International Society of Nephrology Commission on Acute Renal Failure, founding member of the Acute Dialysis Quality Initiative. He received the M.B.B.S. degree (1976) from the Government Medical School in Amritsar, India, and the M.D. (1979) and D.M. (1981) degrees from the Post Graduate Institute of Medical Education and Research in Chandigarh, India. He subsequently completed a nephrology fellowship at the University of Rochester in Rochester New York and obtained his boards in internal medicine (1986) and Nephrology (1988). He has been on the faculty at San Diego since 1988. His reserach interests are in the field of acute renal failure and he has directed several clinical studies in the management of patients with ARF including comparing different dialytic modalities, conducting large multicenter observational studies of ARF with the PICARD group, evaluating different predictive models for outcomes in ARF, investigating the role of cytokine removal by dialysis membranes in sepsis and ARF, and evaluating techniques for determining the amount of excess fluid in dialysis patients.
2:00-3:30
D10 Managing patients with Sepsis: Modifying the Course with (ECOS) (C,N,AP)
Septic patients often require ECOS to allow time for recovery. This workshop covers the rationale and strategies for the practical application of extracorporeal support techniques for sepsis. Case studies will be utilized to delineate different options.
Katja Gist, DO, MSc
I am a dual trained pediatric cardiologist and intensivist. I perform all my clinical care in the cardiac intensive care unit, which is both a surgical and medical intensive care unit for children and adults with congenital and acquired heart disease. I provide expertise in critical care nephrology to my colleagues in the cicu. I perform clinical research in multiple areas of critical care nephrology, predominantly focusing on the systemic complications. At Children's Hospital Colorado, I founded the Pediatric Kidney Injury and Disease Stewardship (PKIDS) program with my nephrology colleague (Dr Soranno). Through PKIDS, we have several hospital wide quality improvement initiatives to reduced nephrotoxic acute kidney injury and enhance AKI awareness. PKIDS also provides a forum for education as well as mentorship of trainees.
Patrick Honore, MD, PhD
Prof Patrick Honoré, MD,PhD,FCCM
Intensivist-Nephrologist
Co-Director of ICU Dept and Prof of Medicine
Coordinator of Critical Care Research Department
Centre Hospitalier Universitaire Brugmann/Brugmann University Hospital
B-1020 Brussels (Laeken ) BELGIUM
Patrick Honoré, graduated from Louvain Medical School as MD (1988), Specialist in Internal Medicine (1993), Intensive Care Specialist (1994) and Nephrologist (1995). During his internship, he completed more than 2 1/2 years specialisation in Nephrology and Dialysis. For almost 5 years, he received ICU training abroad (United Kingdom, Australia and USA). Pr Honoré is Board member of the Belgian Intensive Care Society and closely involved in the Nephrology section of the European Society of Intensive Care Medicine. He is also a distinguished member or consultant of many scientific committees and decision-making organizations dedicated to diagnosis, treatment, and research in the field of acute kidney injury in the critically ill. Pr Honoré authored or co-authored more than 228 peer-reviewed papers ,more than 600 abstracts and more than 75 book chapters . He was also editor of three books dedicated to Critical Care Nephrology.He has been invited as a speaker at more than 650 national and international conferences in almost 100 different countries. He acts as reviewer for more than 45 international journals, including top-ranking journals in the field of critical care medicine and nephrology. He is a member of the editorial board of several 25 high-standard journals. He is also Editor-In-Chief of the Journal of Translational Internal Medicine (open access) since 2013, editor-in-chief of Journal of Translational Critical Care Medicine & Journal of Translational Kidney Research since 2015 (open access too).He is also appointed as section editor for Renal in Annals of Intensive Care starting from February 2016.Since 2009, he fulltime fulfils the position of Head of Clinics in the Intensive Care department of the University Hospital, Vrije Universiteit Brussels (VUB) and became Clinical Tutor and Senior Lecturer at the VUB Faculty of Medicine.Since 2012, he fulfils the position of Full Professor at the VUB Faculty of Medicine. In the ICU department, he leads the Critical Care Nephrology Platform which incorporates intensivists, nephrologists and nurses dedicated to daily education, research and treatment of acute kidney injury. In particular, he directs and organizes continuous renal replacement therapy on a 24/24; 7/7 on-call basis.He has also start a CRRT program using citrate dedicated to small children (less than 10 kg) in the UZB -PICU since 2013.Since January 2018, he is holding the position of Co-Director of ICU Department , ICU Research Director, Prof of Medicine at CHU-Brugmann University Hospital
Matthieu LeGrand, MD
Pr Matthieu Legrand is Professor of Anesthesiology and Critical care medicine. He holds a PhD in physiology. He Works in the Department of anesthesiology, Critical care and burn unit of St-Louis hospital, university Paris Diderot, France. He has carried preclinical and clinical research in the field of critical care medicine with a special interest in critical care nephrology, sepsis and in burn critical care. He has served as a reviewer for several peer-review journals and expert in the field of critical care for several commitees and task forces.
2:00-3:30
E11 Shared Decision Making in the ICU (I,N,AP)
NURSES TRACK (E Series)
Enabling effective communication among caregivers, patients and their surrogates is a key feature of critical care management. This workshop will provide a patient centered approach to equip participants with the best approaches for shared decision making.
Noel Gibney, MB FRCP(C)
Current Position:
Professor, Department of Critical Care Medicine,Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Medical School:
University College Dublin, Ireland
Internal Medicine/Nephrology:
St. Vincents Hospital, Dublin, Ireland
Pulmonary Medicine:
University of Alberta, Edmonton, AB, Canada
Critical Care Medicine:
Harvard University, Cambridge, MA, USA
Interests:
CRRT, Sepsis, Information Technology
Marla Levy, Patient Advocate
Marla Levy will be sharing her journey through four open heart surgeries, and six days on life support which caused AKI and then CKD. Since her recent recovery, she has been passionate about partnering with the medical community in hopes to shine light on how she experienced the continuum of care in both the acute care setting and also in the outpatient dialysis center. Hearing Marla’s story allows others to see the world through a patient’s eyes. It is a completely different perspective which cannot help but evoke new questions on how nephrology patients are treated today, and how to help them avoid the unnecessary pitfalls they continue to fall into. Her honesty, candor and humor are both refreshing and educational.
Gita Mehta, MD
2:00-3:30
F12 Pediatric AKI and RRT: Beyond the Basics (I,N,AP)
This workshop will highlight the epidemiology and best practices for AKI management and CRRT, peritoneal dialysis and tandem therapies application in neonates and children.
David Askenazi, MD, MSPH
Dr. Askenazi is the Medical Director of the Pediatric and Infant Center for Acute Nephrology (PICAN), whose mission is to impove the outcomes of infants and children at risk for acute kidney disease by performing excellent comprehensive multi-disciplinary care, research and education. Dr. Askenazi's research interest include: a) the role that acute kidney injury (AKI) has on short and long-term outcomes in neonates and pediatric patients, b) testing therapies to improve the short and long-term outcomes of neonates and pediatric patients with AKI, and c) improving the definition of neonatal AKI using urinary and serum biomarkers of AKI.
Scott Sutherland, MD
Scott M. Sutherland, MD is a Clinical Professor of Pediatric Nephrology at the Lucile Packard Children's Hospital / Stanford University Medical Center. He is the medical director for apheresis and acute dialysis therapies and co-directs the Cardiorenal Clinic. His research interests include intensive care nephrology, AKI, CRRT, and fluid overload.
Michael Zappitelli, MD, MSc
Michael Zappitelli, MD, MSc practices Pediatric Nephrology, currently Assistant Professor in Pediatrics and Director of the Extracorporeal Blood Therapy and Peritoneal Dialysis Program in Montreal Canada. After training in Pediatric Nephrology and in Epidemiology and Biostatistics at McGill University, Montreal, Canada (2003-2005), he completed a research fellowship in Pediatric Critical Care Nephrology at Texas Children's Hospital, Baylor College of Medicine, Houston, Texas (2005-2007). He has performed research in estimating glomerular filtration rate in children, using serum creatinine and cystatin C-based equations, has published manuscripts on the use of early biomarkers of acute kidney injury in children and on the validation of a pediatric definition for acute kidney injury and has written several book chapters on diagnosis and management of pediatric acute kidney injury. He also performed research in the area of nutritional provision in children treated with continuous renal replacement therapy. Currently, he continues to perform research in early biomarkers of acute kidney injury in children and on epidemiology and definition of pediatric acute kidney injury.
Plenary 2 MINI-SYMPOSIA
Acute Kidney Injury (AKI): Pathophysiology
4:00-6:30
Emmanuel Burdmann, MD, PhD
Dr. Emmanuel A. Burdmann attended medical school at the University of So Paulo Medical School, So Paulo, Brazil and completed residency in Internal Medicine and fellowships in Nephrology at Hospital das Clnicas, University of So Paulo Medical School, So Paulo, Brazil. He received his Doctorate in Nephrology from the University of So Paulo Medical School and did a post-doc research fellowship at the Nephrology Division of the Oregon Health Sciences University, Portland, Oregon. Dr. Burdmann is the past-president of the Latin-American Society of Nephrology and Hypertension and is currently the president of the Brazilian Society of Nephrology. His current academic position is as Associate Professor of Nephrology at the So Jos do Rio Preto Medical School, where he is responsible for the care of the AKI patients and for the Post-Graduation Program. Dr Burdmann serves as Associate-Editor in the Clinical Journal of the American Society of Nephrology and in Nephrology, Dialysis, and Transplantation. He is member of AKIN and KDIGO. His research interests centers on acute kidney injury and drugs and animal venoms nephrotoxicity.
Mitra Nadim, MD, FASN
Mitra Nadim is an Associate Professor of Clinical Medicine in the Division of Nephrology and Hypertension at the University of Southern California. She completed her medical school at UCLA, Internal Medicine Residencey at the Beth Israel Hospital in Boston and Nephrology Fellowship at Brigham and Women’s / Massachusetts General Hospital joint program. She is the the renal system chair for the Year 2 Medical School curriculum at Keck School of Medicine and the Director of USC’s Hypertension Center.
4:00-4:15
Cardiac Surgery Associated AKI: Have We Figured it Out?
Room: Coronado Ballroom
Andrew Shaw, MB, FRCA, FRCPC, FFI
Dr Shaw is Professor of Anesthesiology and Executive Vice Chair, Dept of Anesthesiology at Vanderbilt University Medical Center, Nashville, TN. He is a Fellow of the Royal College of Anaesthetists (UK) and a Fellow of the American College of Critical Care Medicine. He has practiced cardiothoracic anesthesiology and critical care medicine for more than 20 years in the UK and USA, and has authored 3 major textbooks and more than 130 original papers. His research interests lie in clinical and translational studies of outcomes following cardiothoracic surgery, particularly acute kidney injury after heart surgery, and personalized medicine.
4:15-4:30
AKI and ARDS: First Cousins?
Room: Coronado Ballroom
Kathleen Liu, MD, PhD, MAS
Kathleen D. Liu, MD, PhD, MAS is a Professor in the Departments of Medicine and Anesthesia, Divisions of Nephrology and Critical Care Medicine at the University of California, San Francisco. Dr. Liu graduated from the University of California, San Francisco and trained as a resident at the Brigham and Womens Hospital in Boston. She trained in nephrology and critical care at the University of California, San Francisco. She is board-certified in both nephrology and critical care. Her research interests include biomarkers of kidney disease, acute kidney injury and acute lung injury.
4:30-4:45
The Kidney in Pregnancy: Adaptive and Maladaptive Responses
Room: Coronado Ballroom
Ravi Thadhani, MD
4:45-5:00
Introduction
Room: Coronado Ballroom
Ravindra Mehta, MBBS, MD, DM, FACP
Dr. Mehta is Professor of Medicine in the Division of Nephrology and Associate Chair for Clinical Affairs in the Department of Medicine at the University of California, San Diego (UCSD) where he directs the Clinical nephrology and dialysis programs. He is also the Chair of the International Society of Nephrology Commission on Acute Renal Failure, founding member of the Acute Dialysis Quality Initiative. He received the M.B.B.S. degree (1976) from the Government Medical School in Amritsar, India, and the M.D. (1979) and D.M. (1981) degrees from the Post Graduate Institute of Medical Education and Research in Chandigarh, India. He subsequently completed a nephrology fellowship at the University of Rochester in Rochester New York and obtained his boards in internal medicine (1986) and Nephrology (1988). He has been on the faculty at San Diego since 1988. His reserach interests are in the field of acute renal failure and he has directed several clinical studies in the management of patients with ARF including comparing different dialytic modalities, conducting large multicenter observational studies of ARF with the PICARD group, evaluating different predictive models for outcomes in ARF, investigating the role of cytokine removal by dialysis membranes in sepsis and ARF, and evaluating techniques for determining the amount of excess fluid in dialysis patients.
5:00-5:30
The Past
Room: Coronado Ballroom
Steven Alexander, MD
Current: Professor of Pediatrics; Chief, Pediatric Nephrology; Medical Director, Pediatric Dialysis and Kidney Transplantation; Stanford University Medical Center and Lucile Packard Children's Hospital at Stanford. Medical Director, Stanford/Packard Center for Translational Research in Medicine; Member, CRRT 2008 Pediatrics Planning Committee.
Training: Baylor College of Medicine/Texas Children's Hospital (Pediatrics; Pediatric Nephrology)
Former Institutions: Oregon Health Sciences Center; University of Texas Southwestern Medical Center
Claudio Ronco, MD
Actual Position:
Dr. Claudio Ronco
Director
Department of Nephrology
St. Bortolo Hospital
Viale Rodolfi 16
I-36100 Vicenza
Italy
Name: Claudio Ronco
Date of birth: July 12, 1951
Education: High School Diploma at Vicenza Classic Lyceum A.Pigafetta in 1970 with the score: 45/60. Dr. Ronco Graduated in Medicine at University of Padua in 1976 with the score 110/110 and merit debating an experimental thesis on title Aspects of the Nitrogen metabolism in the nephrotic syndrome.
From 1973 to 1976 has been intern at Institute of Clinical Internal Medicine I^ of the University of Padua, directed by Prof. E. Fiaschi, in the Nephrology Department II, under the supervision of the Prof. G. Maschio.
Postgraduate training: From July 1976 to November 1977 he has been internal resident at the Division of Internal Medicine of the St. Bortolo Hospital in Vicenza, directed by Prof. D. Cor.
In 1979 he has achieved the Specialization Diploma on Medical Nephrology at The postgraduate school of internal medicine of the University of Padua, with the score 70/70 debating a thesis on the new methodologies for the measurement of the urinary bicarbonate
In 1989 he has achieved the Diploma of Specialization in Pediatric Nephrology at University of Naples.
1982: Visiting Fellow at the Mount Sinai Hospital in New York, Department of Internal medicine, Nephrology Division, for four months. He carried out studies on hemofiltration and glomerular filtration with J.P. Bosh, S. Glabman and M. Levitt.
1984: Visiting Physician at the Mount Sinai Hospital In New York for two weeks and at VA Hospital in Los Angeles for two weeks.
1985: Visiting professor at the Nephrology Division of the George Washington University Hospital, Washington DC, and NIH at National Naval Medical Center of Bethesda for three months.
1988: Visiting professor at the Renal and Hypertension Division of George Washington University for three months.
1991: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
1995: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
Teaching acitivity and Academic Qualifications: From 1978 to 1984 he has been in charge of the teaching program of Nephrology and Dialysis at Professional Nursing School in Vicenza.
During the academic years 1989-01 he has been in charge of teaching Dialytic therapy at Specialization School in Medical Nephrology of Padua University where he holds a post of Professor of Nephrology in charge of the teaching program concerning Hemodialysis and renal replacement therapies in critically ill patients.
October 1999-December 2000: Professor of Medicine at Albert Einstein College of Medicine and Director of the Renal laboratory at the Beth israel Medical Center in New York.
In the last ten years Professor Ronco was asked to deliver lectures and seminars in several Universities.
He has delivered in meetings and seminars more than 300 lectures and presentations.
In 1982 he introduced in Italy the use of continuous hemofiltration and in 1986 he published the first series of neonates treated with arteriovenous hemofiltration.
In 1985 He contributed to the introduction in Europe of high flux dialysis and derived therapies. He also established the dangerous effect of backfiltration in a contaminated dialysis fluid condition.
He has conducted a series of clinical and experimental researches in the following fields:
- Kinetics of fluid and solute removal in peritoneal dialysis and hemodialysis
- Treatment of Acute renal failure with intermittent and continuous therapies
- Renal replacement therapy in the neonate
- Development of new treatment modalities for acute and chronic renal failure.
- Studies on biomaterials
- Studies on glomerular filtration in humans and renal functional reserve
- Renal physiology in pregnancy
- Hydraulics and flow dynamics in the extracorporeal circulation
- Adequacy of dialysis
- Acid-Base Balance in uremia and dialysis
- Acute renal failure and Critical Care Nephrology
Professional employement and Hospital appointments:
Assistant of clinical nephrology from 1977 to 1984 at Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Associate of clinical nephrology from 1984 at Department of Nephrology , St. Bortolo Hospital, Vicenza, Italy.
From 1984 he is director of the hemodialysis and peritoneal dialysis center of the Department of Nephrology at St. Bortolo Hospital, Vicenza, Italy.
From October 25, 1999 to December 1st 2000 Dr. Ronco has been Director of the research laboratory of Hemodialysis at the Beth Israel Medical center of New York and Visiting Professor of Medicine at the Albert Einstein College of Medicine of new York
Today Dr. Ronco is director of the Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Board certification: In 1989 he has achieved in Rome, the National License for Nephrology Chair and Directional Functions, with the score 94/100.
Professional Society Membership: He is mamber of the council of several scientific societies and he is editor in chief of the international journal of artificial organs and contributions to nephrology.
Awards and honors:
1983 Schwartz Award, for the best paper of the year at St. Bortolo Hospital.
1984 G.F. Volpato Grant for the best research project on acute renal failure in Italy
1989 Best paper Prize at the Italian Society of nephrology meeting.
1991 ESAO RESEARCH AWARD for the best paper presented at the European Society for Artificial Organs.
1996 Arturo Borsatti Award of Padova University as a best nephrologist of the year.
2004 Lifetime achievement award
Other professional activities: He has organized several congresses and meetings in the area of nephrology and Intensive care from 1982 to today.
He is member of several advisory groups for clinical trials and dialysis research.
Lectures and publications: Dr. Ronco has coauthored 560 papers, 36 book chapters, 26 books, 7 monographic journal issues and has delivered more than 300 lectures in international meetings and universities. His personal impact factor calculated at december 2002 is 391.
5:30-6:00
The Present
Room: Coronado Ballroom
Stuart Goldstein, MD
Dr. Goldstein serves as Director for the Center for Acute Care Nephrology (CACN) at Cincinnati Children's Hospital Medical Center. The CACN's mission is to coordinate all AKI related clinical, research and outcomes efforts at CCHMC and to function as a nexus for coordinating multi-center pediatric AKI research. Dr. Goldstein is the Founder and Principal Investigator of the Prospective Pediatric AKI Research Group (www.ppaki.org), a 50 center international pediatric acute care nephrology research consortium that will focuses on pediatric AKI epidemiology, interventional trials, device evaluation and genetic studies. Dr. Goldstein is also the program director for the only Pediatric Acute Care Nephrology fellowship in the United States.
John Kellum, MD
John A. Kellum, MD, FACP, MCCM
John A. Kellum, MD, MCCM is Professor of Critical Care Medicine, Medicine, Bioengineering and Clinical and Translational Science, and Vice Chair for Research within the Department of Critical Care Medicine and Director of the Center for Critical Care Nephrology at the University of Pittsburgh.
Dr. Kellum received his medical degree from the Medical College of Ohio in 1984. His postgraduate training includes an internship and residency in Internal Medicine at the University of Rochester, NY, and a Fellowship in Critical Care Medicine at the University of Pittsburgh Medical Center.
Dr. Kellum is actively involved in education, research and administration. Dr. Kellum’s research interests span various aspects of Critical Care Medicine, but center in critical care nephrology, sepsis and multi-organ failure, and clinical epidemiology, including consensus development and research methodology. He has authored more than 250 publications and has won several awards for teaching. He lectures widely and has given more than 300 seminars and invited lectures worldwide related to his research.
6:00-6:30
The Future
Room: Coronado Ballroom
Rajit Basu, MD, MS, FCCM
Dr. Basu is dedicated to improving the recognition, treatment, and outcomes of critically ill children suffering acute kidney injury. As Co-Director of the Center for Acute Care Nephrology at Cincinnati Children's Hospital, Dr. Basu oversees projects in the pediatric intensive care unit investigating AKI prediction by risk stratified optimization of biomarkers (renal angina), biomarker and fluid overload directed renal replacement therapy initiation, and use of the EMR to provide clinical decision support for management of AKI and fluid balance. Prior to arriving at Cincinnati Children's in 2009, Dr. Basu completed his Pediatric Critical Care fellowship and Pediatric residency at Northwestern University in Chicago. Originally from South Bend, Indiana, he is a graduate of Indiana University Medical School and the University of Notre Dame (undergraduate degree in Biochemistry).
Azra Bihorac, MD, MS, FCCM, FASN
Azra Bihorac leads large multidisciplinary research partnership PrismaP (Precision and Intelligence in Medicine) that brings together experts in the field of predictive modeling, medical informatics and autonomic networks. Her team is developing machine learning and informatics tool for real-time risk stratification and annotation of hospital-acquired complications that would allow management to be tailored to a patients’ “personal clinical profile” using clinical data gathered during routine care.
6:30
Adjourn
Room: Coronado Ballroom
6:30-8:30
Exhibit Reception and Poster Session
Wednesday, Morning, February 26
7:00am-4:30pm
Registration Open
MEET THE EXPERTS BREAKFASTS (elective events)
7:00-8:15
7:00-8:15
ME3 MEET THE EXPERT
How I Use AKI Biomarkers in My Practice
John Kellum, MD
John A. Kellum, MD, FACP, MCCM
John A. Kellum, MD, MCCM is Professor of Critical Care Medicine, Medicine, Bioengineering and Clinical and Translational Science, and Vice Chair for Research within the Department of Critical Care Medicine and Director of the Center for Critical Care Nephrology at the University of Pittsburgh.
Dr. Kellum received his medical degree from the Medical College of Ohio in 1984. His postgraduate training includes an internship and residency in Internal Medicine at the University of Rochester, NY, and a Fellowship in Critical Care Medicine at the University of Pittsburgh Medical Center.
Dr. Kellum is actively involved in education, research and administration. Dr. Kellum’s research interests span various aspects of Critical Care Medicine, but center in critical care nephrology, sepsis and multi-organ failure, and clinical epidemiology, including consensus development and research methodology. He has authored more than 250 publications and has won several awards for teaching. He lectures widely and has given more than 300 seminars and invited lectures worldwide related to his research.
Alex Zarbock, MD
Dr. Zarbock is a Clinician Scientist and the Director and Chair of the Department of Anesthesiology and Critical Care Medicine, at the University of Münster, Germany. He acquired training at the University of Münster (Anesthesiology and Critical Care Medicine). Dr. Zarbock is supported by the German Research Foundation. His research interests span various aspects of Critical Care Medicine, but center in critical care nephrology (renal replacement therapy), sepsis and organ protection. Dr. Zarbock’s current projects include measures to avoid acute kidney injury after surgery and the timing of renal replacement therapy in critically ill patients with acute kidney injury. He is also author and co-author of over 140 scientific articles and book chapters.
7:00-8:15
ME4 MEET THE EXPERT
What Fluids do I Use Perioperatively?
Azra Bihorac, MD, MS, FCCM, FASN
Azra Bihorac leads large multidisciplinary research partnership PrismaP (Precision and Intelligence in Medicine) that brings together experts in the field of predictive modeling, medical informatics and autonomic networks. Her team is developing machine learning and informatics tool for real-time risk stratification and annotation of hospital-acquired complications that would allow management to be tailored to a patients’ “personal clinical profile” using clinical data gathered during routine care.
Andrew Shaw, MB, FRCA, FRCPC, FFI
Dr Shaw is Professor of Anesthesiology and Executive Vice Chair, Dept of Anesthesiology at Vanderbilt University Medical Center, Nashville, TN. He is a Fellow of the Royal College of Anaesthetists (UK) and a Fellow of the American College of Critical Care Medicine. He has practiced cardiothoracic anesthesiology and critical care medicine for more than 20 years in the UK and USA, and has authored 3 major textbooks and more than 130 original papers. His research interests lie in clinical and translational studies of outcomes following cardiothoracic surgery, particularly acute kidney injury after heart surgery, and personalized medicine.
BREAKFAST SYMPOSIA
Breakfast Symposia listed below are hosted by the Conference (RSVP Required)
Selection made during registration
7:00-8:15
Breakfast Symposium C. Innovations in Caring for Patients with Dysnatremias
CME Available
Dysnatremias are commonly encountered in ICU patients and are often difficult to manage. This symposium will cover the pathophysiology of hypo and hypernatremia and discuss the practical issues for management of these disorders with novel agents and describe how RRT can be used for severe disorders.
Yessavan (Moderator)
Qian and Neyra (Discussants)
Javier Neyra
Qi Qian, MD
Dr. Qi Qian is a faculty nephrologist and Professor of Medicine and Professor of Physiology at the Mayo Clinic College of Medicine and Mayo Graduate School, USA. She is the Director of the Mayo Clinic Rochester Nephrology Hospital Practice. She is also an adjunct Professor of Medicine at four top universities in China (Nanjing University School of Medicine in Nanjing, Fourth Military Medical University in Xi’an, Zhejiang University in Hangzhou, and Fudan University, Shanghai, China)
A graduate of the Shanghai 2nd Medical University, Dr. Qian received her post-graduate training in medicine and nephrology at the Albert Einstein College of Medicine, Bronx, New York and was recruited to join the staff at Mayo Clinic upon her graduation from fellowship training in 1999. Dr. Qian's professional focus is on patient care, clinical/translational research and education in the area of renal tubular disorders. In the years of 2000-2008, she conducted basic science research on the renal/vascular pathophysiology through funding from Mayo Clinic Foundation and the National Institutes of Health (NIH-NIDDK). Her expertise in renal and vascular physiology and pathophysiology adds an important dimension to her management of patients with renal tubular diseases.
Dr. Qian also heads the Mayo Clinic Acid-Base Electrolyte Interest Group. She is the principal investigator on a number of studies investigating the effects of electrolyte alterations and renal tubular function. Dr. Qian is an award-winning educator at Mayo Clinic. She has mentored a large number of trainees and is an author and content expert for “AskMayoExpert”, a popular Mayo Clinic web-based medical practice reference for clinicians all over the United States. She currently serves as the president of the Chinese American Society of Nephrology and an ISN Educational Ambassador.
Lenar Yessayan, MD, MS
Dr. Yessayan is an Associate Professor of Medicine at the University of Michigan. He is the Medical Director of the Acute Dialysis Program and CRRT at the University of Michigan. He received his bachelor of science in biology and his medical degree from the American University of Beirut in Lebanon. He received his Master of Science in Clinical Research Design and Data Analysis from the University of Michigan in 2013. Dr. Yessayan completed his Internal Medicine Residency and Nephrology and Critical Care Fellowships at Henry Ford Hospital in Detroit, Michigan, USA. He is board certified in Internal Medicine, Nephrology, and Critical Care Medicine and been practicing since 2009. His research interests lie in the fields of acute kidney injury, hemodynamic monitoring, medical device therapies to treat systemic inflammatory conditions and development of effluent sensing technologies for real time monitoring of solutes during extracorporeal therapies
7:00-8:15
Breakfast Symposium D. Managing AKI in the Patient with Cancer
CME Available
The number of anticancer drugs are increasingly expanding and commonly cause kidney injury. This symposium will discuss how to prevent drug nephrotoxicity, adjust doses of anticancer medicines and manage patients who develop AKI in the setting cancer therapy.
Ostermann (Moderator)
Rosner and Goldstein (Discussants)
Stuart Goldstein, MD
Dr. Goldstein serves as Director for the Center for Acute Care Nephrology (CACN) at Cincinnati Children's Hospital Medical Center. The CACN's mission is to coordinate all AKI related clinical, research and outcomes efforts at CCHMC and to function as a nexus for coordinating multi-center pediatric AKI research. Dr. Goldstein is the Founder and Principal Investigator of the Prospective Pediatric AKI Research Group (www.ppaki.org), a 50 center international pediatric acute care nephrology research consortium that will focuses on pediatric AKI epidemiology, interventional trials, device evaluation and genetic studies. Dr. Goldstein is also the program director for the only Pediatric Acute Care Nephrology fellowship in the United States.
Marlies Ostermann, MD
Dr Ostermann is a Consultant in Critical Care & Nephrology at Guys & St Thomas Foundation Trust, London and Honorary Senior Lecturer at Kings College London.
After medical school in Goettingen (Germany), she did her postgraduate training in London and Canada. She holds a PhD degree from the University of Goettingen, an MD degree from the University of London and a postgraduate Diploma in Medical Education.
She is an active member of the European Society of Intensive Care Society, Renal Association and Intensive Care Society UK, and a Fellow of the Faculty of Intensive Care Medicine. She is also a co-founder of the London AKI Network. Her research interests include acute kidney injury in critically ill and all aspects of renal replacement therapy.
Mitchell Rosner, MD
Dr. Rosner is currently the Henry B. Mulholland Professor of Medicine at the University of Virginia School of Medicine as well as the Chairman of the Department of Medicine. Dr. Rosner serves on the executive committee of training program directors for the American Society of Nephrology. His research interests include: sodium and water metabolism and acute kidney injury. He is a fellow of the American Society of Nephrology and a fellow of the American College of Physicians
Standard Workshop Group 3
8:15-9:45
8:15-9:45
A13 Preventing AKI: From Surveillance to Intervention (C,N,AP)
This workshop will describe the current status of methods to identify patients at high risk for AKI and techniques for electronic surveillance. Strategies and tools for preventing AKI in different settings will be discussed.
Kianoush Kashani, MD
Kianoush Kashani, MD is a consultant in the Division of Nephrology and Hypertension, Division of Pulmonary and Critical Care at Mayo Clinic, Rochester. His academic rank is Professor in Internal Medicine and Assistant Professor in Medical Education. His research interest is acute kidney injury, electrolyte disorders, simulation medicine, and critical care point-of-care ultrasonography.
Andrew Lewington, MD
Dr Andrew Lewington studied medicine as an undergraduate in London before pursuing a career in renal medicine. He studied in Leicester UK and Washington University USA where he worked in Mark Hammermann's laboratory investigating the molecular mechanisms underlying ischaemic acute kidney injury.Dr Lewington was appointed consultant renal physician/honorary senior lecturer at Leeds Teaching Hospitals in 2004. He works as an NHS clinician providing a specialist renal opinion on acutely ill patients on the ICU across Leeds. He was an expert adviser on the UK NCEPOD adding insult to injury AKI study, working from his position on the Renal Association executive committee to improve the care that patients who develop AKI receive. He is the lead author of the 5th Renal Association AKI clinical practice guidelines. During his time in Leeds he has developed collaborative research with an internationally recognised proteomics group. He currently has a nephrology fellow investigating potential proteomic biomarkers of kidney dysfunction in the early phase following kidney transplantation. He is Clinical Sub Dean for the Leeds Teaching Hospitals and is heavily involved in the delivery of undergraduate medical education at the University of Leeds.
Michael Zappitelli, MD, MSc
Michael Zappitelli, MD, MSc practices Pediatric Nephrology, currently Assistant Professor in Pediatrics and Director of the Extracorporeal Blood Therapy and Peritoneal Dialysis Program in Montreal Canada. After training in Pediatric Nephrology and in Epidemiology and Biostatistics at McGill University, Montreal, Canada (2003-2005), he completed a research fellowship in Pediatric Critical Care Nephrology at Texas Children's Hospital, Baylor College of Medicine, Houston, Texas (2005-2007). He has performed research in estimating glomerular filtration rate in children, using serum creatinine and cystatin C-based equations, has published manuscripts on the use of early biomarkers of acute kidney injury in children and on the validation of a pediatric definition for acute kidney injury and has written several book chapters on diagnosis and management of pediatric acute kidney injury. He also performed research in the area of nutritional provision in children treated with continuous renal replacement therapy. Currently, he continues to perform research in early biomarkers of acute kidney injury in children and on epidemiology and definition of pediatric acute kidney injury.
8:15-9:45
B14 Personalized Fluid Management with CRRT (A)
Achieving fluid balance and maintaining plasma composition is key for effective CRRT. This workshop will use case studies to discuss strategies for fluid management in CRRT to achieve patient driven outcomes for fluid, electrolyte and acid base balance.
Ravindra Mehta, MBBS, MD, DM, FACP
Dr. Mehta is Professor of Medicine in the Division of Nephrology and Associate Chair for Clinical Affairs in the Department of Medicine at the University of California, San Diego (UCSD) where he directs the Clinical nephrology and dialysis programs. He is also the Chair of the International Society of Nephrology Commission on Acute Renal Failure, founding member of the Acute Dialysis Quality Initiative. He received the M.B.B.S. degree (1976) from the Government Medical School in Amritsar, India, and the M.D. (1979) and D.M. (1981) degrees from the Post Graduate Institute of Medical Education and Research in Chandigarh, India. He subsequently completed a nephrology fellowship at the University of Rochester in Rochester New York and obtained his boards in internal medicine (1986) and Nephrology (1988). He has been on the faculty at San Diego since 1988. His reserach interests are in the field of acute renal failure and he has directed several clinical studies in the management of patients with ARF including comparing different dialytic modalities, conducting large multicenter observational studies of ARF with the PICARD group, evaluating different predictive models for outcomes in ARF, investigating the role of cytokine removal by dialysis membranes in sepsis and ARF, and evaluating techniques for determining the amount of excess fluid in dialysis patients.
John Prowle, MA, MSc, MD, FRCP
Dr Prowle is a Senior Clinical Lecturer in Intensive Care Medicine within the Critical Care and Perioperative Medicine Research Group at Barts and the London School of Medicine and Dentistry, Queen Mary University of London and is an Honorary Consultant Physician in Intensive Care Medicine and Nephrology at the Royal London Hospital, Barts Health NHS Trust, London, UK. He graduated in medicine from the University of Cambridge in 1999 and undertook Doctoral Research under the supervision of Prof Rinaldo Bellomo in Melbourne, Australia leading to the award of his research doctorate in 2013. Dr Prowle’s academic interests include the Pathogenesis, Diagnosis and Treatment and Outcomes of Acute Kidney Injury, Continuous Renal Replacement Therapies in the ICU, Fluid Therapy and Medical Complications of Major Surgery. Since 2009 he has co-authored over 80 peer-reviewed publications and book chapters, including chapters related to Acute Kidney Injury in the latest editions of the Oxford Textbook of Clinical Nephrology and the Oxford Textbook of Critical Care.
8:15-9:45
C15 Nutritional Assessment and Adjustments for Patients on RRT (A,N)
Adequate nutrition is a key to improving outcome from critical illness. Patients treated with RRT have their nutritional status further affected by the procedures and require adjustments to ensure an adequate amount. This workshop will focus on the principles for appropriate nutritional assessment and adjustments in patients on RRT.
Andrew Davenport, MD, FRCP
I am currently responsible for the planning and organisation and delivery of dialysis treatments in North Central London, UK. The chronic dialysis program comprises around 170 peritoneal dialysis & 520 hemodialysis patients. Acute renal failure requiring renal support is managed between the renal high dependency ward (for non-ventilated patients)and in the intensive care units. The hospital specialises in liver transplantation, neurosurgery and bone marrow transplantation. More than 150 patients with acute renal failure are treated each year.
Patrick Honore, MD, PhD
Prof Patrick Honoré, MD,PhD,FCCM
Intensivist-Nephrologist
Co-Director of ICU Dept and Prof of Medicine
Coordinator of Critical Care Research Department
Centre Hospitalier Universitaire Brugmann/Brugmann University Hospital
B-1020 Brussels (Laeken ) BELGIUM
Patrick Honoré, graduated from Louvain Medical School as MD (1988), Specialist in Internal Medicine (1993), Intensive Care Specialist (1994) and Nephrologist (1995). During his internship, he completed more than 2 1/2 years specialisation in Nephrology and Dialysis. For almost 5 years, he received ICU training abroad (United Kingdom, Australia and USA). Pr Honoré is Board member of the Belgian Intensive Care Society and closely involved in the Nephrology section of the European Society of Intensive Care Medicine. He is also a distinguished member or consultant of many scientific committees and decision-making organizations dedicated to diagnosis, treatment, and research in the field of acute kidney injury in the critically ill. Pr Honoré authored or co-authored more than 228 peer-reviewed papers ,more than 600 abstracts and more than 75 book chapters . He was also editor of three books dedicated to Critical Care Nephrology.He has been invited as a speaker at more than 650 national and international conferences in almost 100 different countries. He acts as reviewer for more than 45 international journals, including top-ranking journals in the field of critical care medicine and nephrology. He is a member of the editorial board of several 25 high-standard journals. He is also Editor-In-Chief of the Journal of Translational Internal Medicine (open access) since 2013, editor-in-chief of Journal of Translational Critical Care Medicine & Journal of Translational Kidney Research since 2015 (open access too).He is also appointed as section editor for Renal in Annals of Intensive Care starting from February 2016.Since 2009, he fulltime fulfils the position of Head of Clinics in the Intensive Care department of the University Hospital, Vrije Universiteit Brussels (VUB) and became Clinical Tutor and Senior Lecturer at the VUB Faculty of Medicine.Since 2012, he fulfils the position of Full Professor at the VUB Faculty of Medicine. In the ICU department, he leads the Critical Care Nephrology Platform which incorporates intensivists, nephrologists and nurses dedicated to daily education, research and treatment of acute kidney injury. In particular, he directs and organizes continuous renal replacement therapy on a 24/24; 7/7 on-call basis.He has also start a CRRT program using citrate dedicated to small children (less than 10 kg) in the UZB -PICU since 2013.Since January 2018, he is holding the position of Co-Director of ICU Department , ICU Research Director, Prof of Medicine at CHU-Brugmann University Hospital
Eric Hoste, MD, PhD
Eric HOSTE
Training
- Doctor in Medicine, Surgery, and Obstetrics, Ghent University, Belgium 1989.
- Board Certified: Internal Medicine, October 1995.
- Board Certified: Intensive Care Medicine 1997.
- PhD Doctorate in the Medical Sciences, 30th November 2004 titled Acute Renal Failure in Critically Ill Patients.
Working career
- Chief of Clinic, Intensive Care Unit, Ghent University Hospital, Belgium
- Research fellow in Critical Care Medicine, The CRISMA laboratory, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, August-December 2003
Author and co-author of
- 42 publications in international peer reviewed journals
- 5 book chapters
8:15-9:45
D16 Managing the Heart Failure Patient with Worsening Renal Function (WRF) (A,N)
Patients with advanced heart failure often develop WRF. It is often difficult to determine which patients can be managed with drug therapy vs requiring RRT. This workshop will describe the practical application and results of different methods to treat heart failure and cardio-renal syndrome including ultrafiltration techniques.
Rajasekara Chakravarthi, MD, DNB (Nephrology)
Dr. Rajasekara Chakravarthi graduated from Mysore University (MBBS) in 1993 and completed MD (internal medicine) from the same university in 1996. Subsequently he trained as a fellow in Nephrology under the guidance of Dr.M.K.Mani between June 1997 to June 1999. He successfully completed the national board of examinations (Nephrology) DNB-NBE India. He worked as a Consultant Nephrologist at JSS medical college and hospitals Mysore between Aug 1999 to Oct 2000 and then as a Consultant Nephrologist at Apollo hospitals Chennai between Oct 2000 to March 2002. He shifted to the city of Hyderabad in March 2002 and started the department of Nephrology at CARE hospitals, the institute of medical sciences. He was the Head of the department of Nephrology CARE hospitals Banjara hills from March 2002 to September 2011. Since September 2011 till Sep 2015 he officiated as the Director Nephrology services CARE group of hospitals India which is a 16 hospitals group spread across the country. Since Sep 2015 till date he is the director of Nephrology services STAR hospitals, Hyderabad. India.
He has keen interest in understanding Acute Kidney Injury and is a member of the AKIN and ADQI (2011, Dublin) (2016, Asiago). He is appointed as faculty of the KDIGO working group on AKI - 2019. He has more than 75 publications in various national and international journals and more than 160 presentations in various conferences. He was a visiting and adjunct faculty to National Institute of Nutrition Hyderabad and JSS University Mysore. He is an organizing committee member and invited faculty for the international CRRT conference held at San Diego yearly since 2005 till date. He is a reviewer for the Indian Journal of nephrology, the official journal of the Indian society of Nephrology, Indian Heart Journal, Journal of Indian College of cardiology, Indian journal of Transplantation and Nephrology and Indian journal of Hypertension. He is presently nominated as a member AKI-committee of the International society of Nephrology. In the year 2016 he has organized and co-chaired the 17th ADQI held at Hyderabad India on Management of AKI in the developing world. He has been organizing AKI and CRRT conferences and works shops since 2004 . He has been part of the active transplantation programme since 1997 at Apollo Hospitals - Chennai, JSS Medical College Hospital - Mysore, Care Group of Hospitals - India and presently at STAR Hospitals - Hyderabad, being part of more than 650 transplantations so far both live related and cadaveric.
He is the founding trustee of the NGO, Care For Your Kidney Foundation (cfykf) started in the year 2015 with the aim of creating awareness in the public regarding kidney disease and preventing kidney disease in the community. So far the foundation has completed more than five thousand screening in the urban slums of Hyderabad. The foundation also subsidizes dialysis and kidney transplants for the needy population of the country.
He is the founding director of Renown clinical services which is a group offering Nephrology services presently to six hospitals in the city of Hyderabad. An Annual meeting on AKI (acute kidney injury) and CRRT is conducted by Renown associates since 2016 namely Selections from Sandiego. This meeting provides training in all modalities of RRT (dialysis) in ICU and brings the highlights of the AKI and CRRT meeting held annually in Sandiego by CRRT Inc. and UCSD. This meeting held at Sandiego annually is into its 25th year.
Patrick Murray, MD
Patrick Murray is Professor of Clinical Pharmacology in University College Dublin, and a consultant physician (clinical pharmacologist & nephrologist) at the Mater Misericordiae University Hospital, Dublin, Ireland.
He received his medical education at University College Dublin, Ireland.
Following his internship at the Mater Misericordiae University Hospital in Dublin, he completed a residency in internal medicine at Hennepin County Medical Center in Minneapolis, Minnesota, USA.
He completed fellowship training programs in nephrology, critical care medicine, and clinical pharmacology at the University Of Chicago Hospitals in Chicago, Illinois, USA.
He is board-certified in nephrology, critical care medicine, and clinical pharmacology.
He practiced as an intensivist, nephrologist, and clinical pharmacologist at the University of Chicago Hospitals from 1996–2008, serving as the fellowship training program director in nephrology, also directing the Acute Dialysis Service.
He has a longstanding interest in research and education to improve the prevention, diagnosis, and therapy of acute kidney injury and nephrotoxicity, and the pharmacotherapy of patients with kidney disease. He is a member of several international consensus groups that have produced guidelines for research and practice in the field of acute kidney injury (ADQI, AKIN, KDOQI).
Since 2008, he has been the Professor of Clinical Pharmacology at University College Dublin, and a Consultant in Nephrology & Clinical Pharmacology at the Mater Misericordiae University Hospital. He is Chair of the Mater Misericordiae University Hospital Drugs & Therapeutics Committee. He is the Clinical Director of the UCD-Mater Clinical Research Centre. In 2011, he was appointed Associate Dean for International Affairs in the UCD School of Medicine and Medical Science. In 2012, he was appointed Director of the Dublin Centre for Clinical Research (DCCR) Consortium Network, and also Clinical Director of the Irish Clinical Research Infrastructure Network (ICRIN). From December 2012 until July 2018, he served as the Dean and Head of the School of Medicine at UCD.
Claudio Ronco, MD
Actual Position:
Dr. Claudio Ronco
Director
Department of Nephrology
St. Bortolo Hospital
Viale Rodolfi 16
I-36100 Vicenza
Italy
Name: Claudio Ronco
Date of birth: July 12, 1951
Education: High School Diploma at Vicenza Classic Lyceum A.Pigafetta in 1970 with the score: 45/60. Dr. Ronco Graduated in Medicine at University of Padua in 1976 with the score 110/110 and merit debating an experimental thesis on title Aspects of the Nitrogen metabolism in the nephrotic syndrome.
From 1973 to 1976 has been intern at Institute of Clinical Internal Medicine I^ of the University of Padua, directed by Prof. E. Fiaschi, in the Nephrology Department II, under the supervision of the Prof. G. Maschio.
Postgraduate training: From July 1976 to November 1977 he has been internal resident at the Division of Internal Medicine of the St. Bortolo Hospital in Vicenza, directed by Prof. D. Cor.
In 1979 he has achieved the Specialization Diploma on Medical Nephrology at The postgraduate school of internal medicine of the University of Padua, with the score 70/70 debating a thesis on the new methodologies for the measurement of the urinary bicarbonate
In 1989 he has achieved the Diploma of Specialization in Pediatric Nephrology at University of Naples.
1982: Visiting Fellow at the Mount Sinai Hospital in New York, Department of Internal medicine, Nephrology Division, for four months. He carried out studies on hemofiltration and glomerular filtration with J.P. Bosh, S. Glabman and M. Levitt.
1984: Visiting Physician at the Mount Sinai Hospital In New York for two weeks and at VA Hospital in Los Angeles for two weeks.
1985: Visiting professor at the Nephrology Division of the George Washington University Hospital, Washington DC, and NIH at National Naval Medical Center of Bethesda for three months.
1988: Visiting professor at the Renal and Hypertension Division of George Washington University for three months.
1991: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
1995: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
Teaching acitivity and Academic Qualifications: From 1978 to 1984 he has been in charge of the teaching program of Nephrology and Dialysis at Professional Nursing School in Vicenza.
During the academic years 1989-01 he has been in charge of teaching Dialytic therapy at Specialization School in Medical Nephrology of Padua University where he holds a post of Professor of Nephrology in charge of the teaching program concerning Hemodialysis and renal replacement therapies in critically ill patients.
October 1999-December 2000: Professor of Medicine at Albert Einstein College of Medicine and Director of the Renal laboratory at the Beth israel Medical Center in New York.
In the last ten years Professor Ronco was asked to deliver lectures and seminars in several Universities.
He has delivered in meetings and seminars more than 300 lectures and presentations.
In 1982 he introduced in Italy the use of continuous hemofiltration and in 1986 he published the first series of neonates treated with arteriovenous hemofiltration.
In 1985 He contributed to the introduction in Europe of high flux dialysis and derived therapies. He also established the dangerous effect of backfiltration in a contaminated dialysis fluid condition.
He has conducted a series of clinical and experimental researches in the following fields:
- Kinetics of fluid and solute removal in peritoneal dialysis and hemodialysis
- Treatment of Acute renal failure with intermittent and continuous therapies
- Renal replacement therapy in the neonate
- Development of new treatment modalities for acute and chronic renal failure.
- Studies on biomaterials
- Studies on glomerular filtration in humans and renal functional reserve
- Renal physiology in pregnancy
- Hydraulics and flow dynamics in the extracorporeal circulation
- Adequacy of dialysis
- Acid-Base Balance in uremia and dialysis
- Acute renal failure and Critical Care Nephrology
Professional employement and Hospital appointments:
Assistant of clinical nephrology from 1977 to 1984 at Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Associate of clinical nephrology from 1984 at Department of Nephrology , St. Bortolo Hospital, Vicenza, Italy.
From 1984 he is director of the hemodialysis and peritoneal dialysis center of the Department of Nephrology at St. Bortolo Hospital, Vicenza, Italy.
From October 25, 1999 to December 1st 2000 Dr. Ronco has been Director of the research laboratory of Hemodialysis at the Beth Israel Medical center of New York and Visiting Professor of Medicine at the Albert Einstein College of Medicine of new York
Today Dr. Ronco is director of the Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Board certification: In 1989 he has achieved in Rome, the National License for Nephrology Chair and Directional Functions, with the score 94/100.
Professional Society Membership: He is mamber of the council of several scientific societies and he is editor in chief of the international journal of artificial organs and contributions to nephrology.
Awards and honors:
1983 Schwartz Award, for the best paper of the year at St. Bortolo Hospital.
1984 G.F. Volpato Grant for the best research project on acute renal failure in Italy
1989 Best paper Prize at the Italian Society of nephrology meeting.
1991 ESAO RESEARCH AWARD for the best paper presented at the European Society for Artificial Organs.
1996 Arturo Borsatti Award of Padova University as a best nephrologist of the year.
2004 Lifetime achievement award
Other professional activities: He has organized several congresses and meetings in the area of nephrology and Intensive care from 1982 to today.
He is member of several advisory groups for clinical trials and dialysis research.
Lectures and publications: Dr. Ronco has coauthored 560 papers, 36 book chapters, 26 books, 7 monographic journal issues and has delivered more than 300 lectures in international meetings and universities. His personal impact factor calculated at december 2002 is 391.
8:15-9:45
E17 Withholding and Withdrawing Care: Ethical Issues in the ICU (I,N,AP)
NURSES TRACK (E Series)
Defining the goals of therapy in context to the patient and family wishes often poses a dilemma particularly when the care team does not concur. This workshop will discuss the principles and practical application of palliative care in managing critically ill patients.
Noel Gibney, MB FRCP(C)
Current Position:
Professor, Department of Critical Care Medicine,Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Medical School:
University College Dublin, Ireland
Internal Medicine/Nephrology:
St. Vincents Hospital, Dublin, Ireland
Pulmonary Medicine:
University of Alberta, Edmonton, AB, Canada
Critical Care Medicine:
Harvard University, Cambridge, MA, USA
Interests:
CRRT, Sepsis, Information Technology
Marla Levy, Patient Advocate
Marla Levy will be sharing her journey through four open heart surgeries, and six days on life support which caused AKI and then CKD. Since her recent recovery, she has been passionate about partnering with the medical community in hopes to shine light on how she experienced the continuum of care in both the acute care setting and also in the outpatient dialysis center. Hearing Marla’s story allows others to see the world through a patient’s eyes. It is a completely different perspective which cannot help but evoke new questions on how nephrology patients are treated today, and how to help them avoid the unnecessary pitfalls they continue to fall into. Her honesty, candor and humor are both refreshing and educational.
Sunita Puri
8:15-9:45
F18 Pediatric AKI and CRRT: Caring for the Patient (I,N,AP)
Review and discussion of best practices to develop your pediatric AKI and CRRT program, identify and treat your young patients with AKI, and to assure delivery of high-quality care in the pediatric setting.
David Askenazi, MD, MSPH
Dr. Askenazi is the Medical Director of the Pediatric and Infant Center for Acute Nephrology (PICAN), whose mission is to impove the outcomes of infants and children at risk for acute kidney disease by performing excellent comprehensive multi-disciplinary care, research and education. Dr. Askenazi's research interest include: a) the role that acute kidney injury (AKI) has on short and long-term outcomes in neonates and pediatric patients, b) testing therapies to improve the short and long-term outcomes of neonates and pediatric patients with AKI, and c) improving the definition of neonatal AKI using urinary and serum biomarkers of AKI.
Rajit Basu, MD, MS, FCCM
Dr. Basu is dedicated to improving the recognition, treatment, and outcomes of critically ill children suffering acute kidney injury. As Co-Director of the Center for Acute Care Nephrology at Cincinnati Children's Hospital, Dr. Basu oversees projects in the pediatric intensive care unit investigating AKI prediction by risk stratified optimization of biomarkers (renal angina), biomarker and fluid overload directed renal replacement therapy initiation, and use of the EMR to provide clinical decision support for management of AKI and fluid balance. Prior to arriving at Cincinnati Children's in 2009, Dr. Basu completed his Pediatric Critical Care fellowship and Pediatric residency at Northwestern University in Chicago. Originally from South Bend, Indiana, he is a graduate of Indiana University Medical School and the University of Notre Dame (undergraduate degree in Biochemistry).
Zaccaria Ricci, MD
Education and training:
Graduation in Medicine on September 1997 at University of “La Sapienza” of Rome, Italy. Specialization in Anesthesiology and Intensive Care on October 2001 at University of “La Sapienza” of Rome, Italy.
Professional experience:
Zaccaria Ricci matured experience in critical care during his period from 2001 to 2006 as a staff clinician in the Intensive Care Unit of the Policlinico Umberto I at the University “La Sapienza” of Rome, Italy. His areas of interest included pharmacological strategies and renal replacement therapies for critically ill patients with acute kidney injury.
His interest and expertise on extracorporeal therapies and blood purification developed in collaboration with the Department of Nephrology Dialysis and Transplantation, Vicenza, Italy, directed by professor Claudio Ronco. In particular, he has focused its main interest in Renal Replacement Dose Delivery and Information Technology applied to new generation machines for acute dialysis. He had the privilege of co-conducting the alpha trials of the Prismaflex and the Carpediem machines.
Since 2006 he is a staff anesthesiologist of the Department of Pediatric Cardiac Surgery at Bambino Gesù Hospital. His work has been devoted to the care of pediatric renal dysfunction and hemodynamic monitoring in the perioperative care of children with congenital heart diseases.
He is author and coauthor of about 200 original articles, reviews and book chapters in the field acute kidney injury diagnosis and therapy and pediatric critical care. He is currently collaborating as a peer reviewer with more than 10 indexed journals in the area of Critical Care and Nephrology. Since October 2009 he is an Associated Faculty Member of Pediatric Critical Care Medicine and in the Editorial Board of the journal Blood Purification. Since October 2013 he is an Associate Editor of the journal BMC Anesthesiology.
SESSION II: CONTROVERSIES IN CRITICAL CARE NEPHROLOGY
Plenary 3 MINI-SYMPOSIA
Challenges in ICU Management
10:00-12:15
Katja Gist, DO, MSc
I am a dual trained pediatric cardiologist and intensivist. I perform all my clinical care in the cardiac intensive care unit, which is both a surgical and medical intensive care unit for children and adults with congenital and acquired heart disease. I provide expertise in critical care nephrology to my colleagues in the cicu. I perform clinical research in multiple areas of critical care nephrology, predominantly focusing on the systemic complications. At Children's Hospital Colorado, I founded the Pediatric Kidney Injury and Disease Stewardship (PKIDS) program with my nephrology colleague (Dr Soranno). Through PKIDS, we have several hospital wide quality improvement initiatives to reduced nephrotoxic acute kidney injury and enhance AKI awareness. PKIDS also provides a forum for education as well as mentorship of trainees.
Eric Hoste, MD, PhD
Eric HOSTE
Training
- Doctor in Medicine, Surgery, and Obstetrics, Ghent University, Belgium 1989.
- Board Certified: Internal Medicine, October 1995.
- Board Certified: Intensive Care Medicine 1997.
- PhD Doctorate in the Medical Sciences, 30th November 2004 titled Acute Renal Failure in Critically Ill Patients.
Working career
- Chief of Clinic, Intensive Care Unit, Ghent University Hospital, Belgium
- Research fellow in Critical Care Medicine, The CRISMA laboratory, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, August-December 2003
Author and co-author of
- 42 publications in international peer reviewed journals
- 5 book chapters
10:15-10:30
AKI After Cardiac Arrest
Room: Coronado Ballroom
Michael Joannidis, Professor, MD
Michael Joannidis, MD. Dr. Joannidis is Professor in Medicine serving as director of the Division of Intensive Care and Emergency Medicine, Dept. General Internal Medicine, Medical University Innsbruck, Austria. He is a certified specialist in Critical Care medicine and Nephrology. His research interests cover several topics of Critical Care Medicine with a major focus on acute renal injury and renal tubular epithelial pathophysiology. He is president of the Austrian Society of General and Medical Intensive Care and Emergency Medicine (OEGIAIN)
10:30-10:45
Liver Disease in the ICU: When should We Offer RRT?
Room: Coronado Ballroom
Mitra Nadim, MD, FASN
Mitra Nadim is an Associate Professor of Clinical Medicine in the Division of Nephrology and Hypertension at the University of Southern California. She completed her medical school at UCLA, Internal Medicine Residencey at the Beth Israel Hospital in Boston and Nephrology Fellowship at Brigham and Women’s / Massachusetts General Hospital joint program. She is the the renal system chair for the Year 2 Medical School curriculum at Keck School of Medicine and the Director of USC’s Hypertension Center.
10:45-11:00
Diuretic Resistance and Elastic Bandage
Room: Coronado Ballroom
Kianoush Kashani, MD
Kianoush Kashani, MD is a consultant in the Division of Nephrology and Hypertension, Division of Pulmonary and Critical Care at Mayo Clinic, Rochester. His academic rank is Professor in Internal Medicine and Assistant Professor in Medical Education. His research interest is acute kidney injury, electrolyte disorders, simulation medicine, and critical care point-of-care ultrasonography.
11:00-11:15
Persistent Critical Illness
Room: Coronado Ballroom
Sean Bagshaw, MD, MSc, FRCPC
Dr. Bagshaw is a Clinician Scientist and Assistant Professor in the Division of Critical Care Medicine, at the University of Alberta in Edmonton, Alberta, Canada. He acquired training at the University of Calgary (Internal Medicine, Critical Care Medicine, Masters of Science Epidemiology) prior to completing a critical care nephrology fellowship in the Department of Intensive Care Medicine, at the Austin Hospital in Melbourne, Australia.
Dr. Bagshaw is supported by a Canada Research Chair in Critical Care Nephrology and a Clinical Investigator Award from Alberta Innovates - Health Solutions. Dr. Bagshaw's main research interests have focused on the clinical, epidemiological and translational issues related to acute kidney injury and the application of extracorporeal blood purification in critically ill patients. Dr. Bagshaw's current projects include diuretic therapy in early acute kidney injury and factors related with the initiation of renal support in critically ill patients. He has published over 100 peer-reviewed papers, numerous book chapters, and peer-reviewed for over 20 medical journals.
Dr. Bagshaw is a member of several organizations including the Canadian Critical Care Society, Canadian Critical Care Trials Group, Australia New Zealand Intensive Care Society, and the Acute Kidney Injury Network, and the Acute Dialysis Quality Initiative.
11:15-11:30
AKI and Risk of Death: Unpicking Correlation From Causation
Room: Coronado Ballroom
John Prowle, MA, MSc, MD, FRCP
Dr Prowle is a Senior Clinical Lecturer in Intensive Care Medicine within the Critical Care and Perioperative Medicine Research Group at Barts and the London School of Medicine and Dentistry, Queen Mary University of London and is an Honorary Consultant Physician in Intensive Care Medicine and Nephrology at the Royal London Hospital, Barts Health NHS Trust, London, UK. He graduated in medicine from the University of Cambridge in 1999 and undertook Doctoral Research under the supervision of Prof Rinaldo Bellomo in Melbourne, Australia leading to the award of his research doctorate in 2013. Dr Prowle’s academic interests include the Pathogenesis, Diagnosis and Treatment and Outcomes of Acute Kidney Injury, Continuous Renal Replacement Therapies in the ICU, Fluid Therapy and Medical Complications of Major Surgery. Since 2009 he has co-authored over 80 peer-reviewed publications and book chapters, including chapters related to Acute Kidney Injury in the latest editions of the Oxford Textbook of Clinical Nephrology and the Oxford Textbook of Critical Care.
11:30-11:45
Delirium in the ICU: Is AKI a Risk Factor ?
Room: Coronado Ballroom
Marlies Ostermann, MD
Dr Ostermann is a Consultant in Critical Care & Nephrology at Guys & St Thomas Foundation Trust, London and Honorary Senior Lecturer at Kings College London.
After medical school in Goettingen (Germany), she did her postgraduate training in London and Canada. She holds a PhD degree from the University of Goettingen, an MD degree from the University of London and a postgraduate Diploma in Medical Education.
She is an active member of the European Society of Intensive Care Society, Renal Association and Intensive Care Society UK, and a Fellow of the Faculty of Intensive Care Medicine. She is also a co-founder of the London AKI Network. Her research interests include acute kidney injury in critically ill and all aspects of renal replacement therapy.
11:45-12:15
SPECIAL LECTURE
Translating Mechanisms to Management Award
TBA
Room: Coronado Ballroom
12:15-12:30
Top Abstract Awards
Room: Coronado Ballroom
LUNCH SYMPOSIA
Lunch Symposia Hosted by Conference (RSVP Required)
Selection made during registration
12:30-2:00
Lunch Symposium W1. Individualizing Care: Challenges and Opportunities for Critical Illness
CME Available
Moderators: Yang and Murray
Precision medicine aims to lead to personalized treatment and improved outcomes. However its application in AKI and critical care faces many challenges including patient characterization and specific targets for timely interventions. This session will discuss approaches to address these challenges and provide a framework for achieving personalized care.
Personalizing Critical Care: Do We Know How to Do it? - Forni
Identifying the Right Patient for the Right Therapy at the Right Time - Wald
When Enough is Enough: Incorporating Palliative Care in the ICU? - Puri
Lui Forni, MD
Patrick Murray, MD
Patrick Murray is Professor of Clinical Pharmacology in University College Dublin, and a consultant physician (clinical pharmacologist & nephrologist) at the Mater Misericordiae University Hospital, Dublin, Ireland.
He received his medical education at University College Dublin, Ireland.
Following his internship at the Mater Misericordiae University Hospital in Dublin, he completed a residency in internal medicine at Hennepin County Medical Center in Minneapolis, Minnesota, USA.
He completed fellowship training programs in nephrology, critical care medicine, and clinical pharmacology at the University Of Chicago Hospitals in Chicago, Illinois, USA.
He is board-certified in nephrology, critical care medicine, and clinical pharmacology.
He practiced as an intensivist, nephrologist, and clinical pharmacologist at the University of Chicago Hospitals from 1996–2008, serving as the fellowship training program director in nephrology, also directing the Acute Dialysis Service.
He has a longstanding interest in research and education to improve the prevention, diagnosis, and therapy of acute kidney injury and nephrotoxicity, and the pharmacotherapy of patients with kidney disease. He is a member of several international consensus groups that have produced guidelines for research and practice in the field of acute kidney injury (ADQI, AKIN, KDOQI).
Since 2008, he has been the Professor of Clinical Pharmacology at University College Dublin, and a Consultant in Nephrology & Clinical Pharmacology at the Mater Misericordiae University Hospital. He is Chair of the Mater Misericordiae University Hospital Drugs & Therapeutics Committee. He is the Clinical Director of the UCD-Mater Clinical Research Centre. In 2011, he was appointed Associate Dean for International Affairs in the UCD School of Medicine and Medical Science. In 2012, he was appointed Director of the Dublin Centre for Clinical Research (DCCR) Consortium Network, and also Clinical Director of the Irish Clinical Research Infrastructure Network (ICRIN). From December 2012 until July 2018, he served as the Dean and Head of the School of Medicine at UCD.
Sunita Puri
Ron Wald, MD
Ron Wald is a nephrologist at St. Michael's Hospital in Toronto where he also serves as the Medical Director of the hospital's Hemodialysis Program. He is an Associate Professor of Medicine at the University of Toronto. His primary research interest is in critical care nephrology and he has been involved in several clinical trials in this area. He is currently co-leading an international randomized controlled trial on the timing of renal replacement therapy in acute kidney injury. Ron's other interests are volume optimization in patients with AKI and the post-discharge care provided to AKI survivors.
Li Yang, MD
Dr. Yang is an Associate Professor of Medicine in the Renal Division of Peking University First Hospital and Associate Director in the Institute of Nephrology at Peking University, where she directs clinical acute kidney injury, renal pathology, and basic research in nephrology. She is committee member of the International Society of Nephrology Commission on Acute Renal Failure. She received the M.D. degree from Peking University in 2001, and has been on the faculty at Peking University First Hospital since 2001. She was a Research Fellow, granted by the International Society of Nephrology, in the renal division of Brigham and Womens Hospital at Harvard Medical School, from 2007-2010. Her research interests are in the fields of acute kidney injury, drug associated kidney diseases and renal pathology.
12:30-2:00
Lunch Symposium W2. Optimizing Fluid Management in the ICU: Fit for Purpose?
CME Available
Moderator: Qian and Joannidis
Fluid administration is an integral component of management, however there is considerable variation in the type and quantity of fluids used and increasing concern that fluid therapy contributes to AKI. This symposium will review the evidence for our current strategy for using crsytalloids, colloids and blood products and provide guidance on best practices to manage patients in different settings.
Perioperative Fluid Management - Shaw
The Patient with Septic Shock - Kellum
Liver and Kidney Dysfunction - Nadim
Michael Joannidis, Professor, MD
Michael Joannidis, MD. Dr. Joannidis is Professor in Medicine serving as director of the Division of Intensive Care and Emergency Medicine, Dept. General Internal Medicine, Medical University Innsbruck, Austria. He is a certified specialist in Critical Care medicine and Nephrology. His research interests cover several topics of Critical Care Medicine with a major focus on acute renal injury and renal tubular epithelial pathophysiology. He is president of the Austrian Society of General and Medical Intensive Care and Emergency Medicine (OEGIAIN)
John Kellum, MD
John A. Kellum, MD, FACP, MCCM
John A. Kellum, MD, MCCM is Professor of Critical Care Medicine, Medicine, Bioengineering and Clinical and Translational Science, and Vice Chair for Research within the Department of Critical Care Medicine and Director of the Center for Critical Care Nephrology at the University of Pittsburgh.
Dr. Kellum received his medical degree from the Medical College of Ohio in 1984. His postgraduate training includes an internship and residency in Internal Medicine at the University of Rochester, NY, and a Fellowship in Critical Care Medicine at the University of Pittsburgh Medical Center.
Dr. Kellum is actively involved in education, research and administration. Dr. Kellum’s research interests span various aspects of Critical Care Medicine, but center in critical care nephrology, sepsis and multi-organ failure, and clinical epidemiology, including consensus development and research methodology. He has authored more than 250 publications and has won several awards for teaching. He lectures widely and has given more than 300 seminars and invited lectures worldwide related to his research.
Mitra Nadim, MD, FASN
Mitra Nadim is an Associate Professor of Clinical Medicine in the Division of Nephrology and Hypertension at the University of Southern California. She completed her medical school at UCLA, Internal Medicine Residencey at the Beth Israel Hospital in Boston and Nephrology Fellowship at Brigham and Women’s / Massachusetts General Hospital joint program. She is the the renal system chair for the Year 2 Medical School curriculum at Keck School of Medicine and the Director of USC’s Hypertension Center.
Qi Qian, MD
Dr. Qi Qian is a faculty nephrologist and Professor of Medicine and Professor of Physiology at the Mayo Clinic College of Medicine and Mayo Graduate School, USA. She is the Director of the Mayo Clinic Rochester Nephrology Hospital Practice. She is also an adjunct Professor of Medicine at four top universities in China (Nanjing University School of Medicine in Nanjing, Fourth Military Medical University in Xi’an, Zhejiang University in Hangzhou, and Fudan University, Shanghai, China)
A graduate of the Shanghai 2nd Medical University, Dr. Qian received her post-graduate training in medicine and nephrology at the Albert Einstein College of Medicine, Bronx, New York and was recruited to join the staff at Mayo Clinic upon her graduation from fellowship training in 1999. Dr. Qian's professional focus is on patient care, clinical/translational research and education in the area of renal tubular disorders. In the years of 2000-2008, she conducted basic science research on the renal/vascular pathophysiology through funding from Mayo Clinic Foundation and the National Institutes of Health (NIH-NIDDK). Her expertise in renal and vascular physiology and pathophysiology adds an important dimension to her management of patients with renal tubular diseases.
Dr. Qian also heads the Mayo Clinic Acid-Base Electrolyte Interest Group. She is the principal investigator on a number of studies investigating the effects of electrolyte alterations and renal tubular function. Dr. Qian is an award-winning educator at Mayo Clinic. She has mentored a large number of trainees and is an author and content expert for “AskMayoExpert”, a popular Mayo Clinic web-based medical practice reference for clinicians all over the United States. She currently serves as the president of the Chinese American Society of Nephrology and an ISN Educational Ambassador.
Andrew Shaw, MB, FRCA, FRCPC, FFI
Dr Shaw is Professor of Anesthesiology and Executive Vice Chair, Dept of Anesthesiology at Vanderbilt University Medical Center, Nashville, TN. He is a Fellow of the Royal College of Anaesthetists (UK) and a Fellow of the American College of Critical Care Medicine. He has practiced cardiothoracic anesthesiology and critical care medicine for more than 20 years in the UK and USA, and has authored 3 major textbooks and more than 130 original papers. His research interests lie in clinical and translational studies of outcomes following cardiothoracic surgery, particularly acute kidney injury after heart surgery, and personalized medicine.
12:30-2:00
Lunch Symposium W3. Digital Health for AKI Management
CME Available
Moderators: Lewington and Sutherland
Digital health techniques have provided new insights and opportunities to risk assess, detect and intervene in several conditions and are being applied to improve prevention and management. This symposium will highlight the advances in the field and their application for AKI.
Artificial Intelligence to Augment Care - Bihorac
Digital Phenotyping for AKI - Koola
Using the Medical Record to Combat AKI - Kashani
Azra Bihorac, MD, MS, FCCM, FASN
Azra Bihorac leads large multidisciplinary research partnership PrismaP (Precision and Intelligence in Medicine) that brings together experts in the field of predictive modeling, medical informatics and autonomic networks. Her team is developing machine learning and informatics tool for real-time risk stratification and annotation of hospital-acquired complications that would allow management to be tailored to a patients’ “personal clinical profile” using clinical data gathered during routine care.
Kianoush Kashani, MD
Kianoush Kashani, MD is a consultant in the Division of Nephrology and Hypertension, Division of Pulmonary and Critical Care at Mayo Clinic, Rochester. His academic rank is Professor in Internal Medicine and Assistant Professor in Medical Education. His research interest is acute kidney injury, electrolyte disorders, simulation medicine, and critical care point-of-care ultrasonography.
Jejo Koola, MD
Andrew Lewington, MD
Dr Andrew Lewington studied medicine as an undergraduate in London before pursuing a career in renal medicine. He studied in Leicester UK and Washington University USA where he worked in Mark Hammermann's laboratory investigating the molecular mechanisms underlying ischaemic acute kidney injury.Dr Lewington was appointed consultant renal physician/honorary senior lecturer at Leeds Teaching Hospitals in 2004. He works as an NHS clinician providing a specialist renal opinion on acutely ill patients on the ICU across Leeds. He was an expert adviser on the UK NCEPOD adding insult to injury AKI study, working from his position on the Renal Association executive committee to improve the care that patients who develop AKI receive. He is the lead author of the 5th Renal Association AKI clinical practice guidelines. During his time in Leeds he has developed collaborative research with an internationally recognised proteomics group. He currently has a nephrology fellow investigating potential proteomic biomarkers of kidney dysfunction in the early phase following kidney transplantation. He is Clinical Sub Dean for the Leeds Teaching Hospitals and is heavily involved in the delivery of undergraduate medical education at the University of Leeds.
Scott Sutherland, MD
Scott M. Sutherland, MD is a Clinical Professor of Pediatric Nephrology at the Lucile Packard Children's Hospital / Stanford University Medical Center. He is the medical director for apheresis and acute dialysis therapies and co-directs the Cardiorenal Clinic. His research interests include intensive care nephrology, AKI, CRRT, and fluid overload.
12:30-2:00
Lunch Symposium W4. Biomarker Enhanced Management of AKI and RRT
CME Available
Moderators: Basu and Cerda
Several biomarkers of kidney damage and function are now available for clinical application, however their use remains limited. This workshop will discuss different approaches for improving patient management with biomarker based care delivery in different settings.
Applying Kidney Biomarkers for Primary Prevention and Early Intervention - Zarbock
Can We Use Biomarkers for RRT Management? - Koyner
AKI Biomarkers in Resource Constrained Settings: What is Required? - Chakaravarthi
Rajit Basu, MD, MS, FCCM
Dr. Basu is dedicated to improving the recognition, treatment, and outcomes of critically ill children suffering acute kidney injury. As Co-Director of the Center for Acute Care Nephrology at Cincinnati Children's Hospital, Dr. Basu oversees projects in the pediatric intensive care unit investigating AKI prediction by risk stratified optimization of biomarkers (renal angina), biomarker and fluid overload directed renal replacement therapy initiation, and use of the EMR to provide clinical decision support for management of AKI and fluid balance. Prior to arriving at Cincinnati Children's in 2009, Dr. Basu completed his Pediatric Critical Care fellowship and Pediatric residency at Northwestern University in Chicago. Originally from South Bend, Indiana, he is a graduate of Indiana University Medical School and the University of Notre Dame (undergraduate degree in Biochemistry).
Jorge Cerda, MD, MS, FACP, FASN
Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY
Clinical Associate Professor of Medicine, Albany Medical College, Albany NY
Fulbright Scholar, 1980
Fellow, American College of Physicians
Fellow, American Society of Nephrology
Organizing Committee, International Conference AKI & CRRT
AKI Advisory Group, American Society of Nephrology
AKI Committee, and "0by25" Initiative, International Society of Nephrology
Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease
Associate Editor, Blood Purification and Kidney International Reports
Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases
Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world
Rajasekara Chakravarthi, MD, DNB (Nephrology)
Dr. Rajasekara Chakravarthi graduated from Mysore University (MBBS) in 1993 and completed MD (internal medicine) from the same university in 1996. Subsequently he trained as a fellow in Nephrology under the guidance of Dr.M.K.Mani between June 1997 to June 1999. He successfully completed the national board of examinations (Nephrology) DNB-NBE India. He worked as a Consultant Nephrologist at JSS medical college and hospitals Mysore between Aug 1999 to Oct 2000 and then as a Consultant Nephrologist at Apollo hospitals Chennai between Oct 2000 to March 2002. He shifted to the city of Hyderabad in March 2002 and started the department of Nephrology at CARE hospitals, the institute of medical sciences. He was the Head of the department of Nephrology CARE hospitals Banjara hills from March 2002 to September 2011. Since September 2011 till Sep 2015 he officiated as the Director Nephrology services CARE group of hospitals India which is a 16 hospitals group spread across the country. Since Sep 2015 till date he is the director of Nephrology services STAR hospitals, Hyderabad. India.
He has keen interest in understanding Acute Kidney Injury and is a member of the AKIN and ADQI (2011, Dublin) (2016, Asiago). He is appointed as faculty of the KDIGO working group on AKI - 2019. He has more than 75 publications in various national and international journals and more than 160 presentations in various conferences. He was a visiting and adjunct faculty to National Institute of Nutrition Hyderabad and JSS University Mysore. He is an organizing committee member and invited faculty for the international CRRT conference held at San Diego yearly since 2005 till date. He is a reviewer for the Indian Journal of nephrology, the official journal of the Indian society of Nephrology, Indian Heart Journal, Journal of Indian College of cardiology, Indian journal of Transplantation and Nephrology and Indian journal of Hypertension. He is presently nominated as a member AKI-committee of the International society of Nephrology. In the year 2016 he has organized and co-chaired the 17th ADQI held at Hyderabad India on Management of AKI in the developing world. He has been organizing AKI and CRRT conferences and works shops since 2004 . He has been part of the active transplantation programme since 1997 at Apollo Hospitals - Chennai, JSS Medical College Hospital - Mysore, Care Group of Hospitals - India and presently at STAR Hospitals - Hyderabad, being part of more than 650 transplantations so far both live related and cadaveric.
He is the founding trustee of the NGO, Care For Your Kidney Foundation (cfykf) started in the year 2015 with the aim of creating awareness in the public regarding kidney disease and preventing kidney disease in the community. So far the foundation has completed more than five thousand screening in the urban slums of Hyderabad. The foundation also subsidizes dialysis and kidney transplants for the needy population of the country.
He is the founding director of Renown clinical services which is a group offering Nephrology services presently to six hospitals in the city of Hyderabad. An Annual meeting on AKI (acute kidney injury) and CRRT is conducted by Renown associates since 2016 namely Selections from Sandiego. This meeting provides training in all modalities of RRT (dialysis) in ICU and brings the highlights of the AKI and CRRT meeting held annually in Sandiego by CRRT Inc. and UCSD. This meeting held at Sandiego annually is into its 25th year.
Jay Koyner, MD
Dr. Koyner is an Associate Professor of Medicine in the Section of Nephrology at the University of Chicago. He completed his Internal Medicine and Nephrology training at the University of Chicago Medical Center where he currently serves as the medical director of the Inpatient Dialysis Unit and Director of ICU Nephrology. His critical care nephrology research interests have focused on the utilization of plasma and urine biomarkers to improve patient risk stratification and outcomes in the setting of AKI. In addition to biomarkers, other research interests include predictive analytics, AKI following cardiac surgery, CRRT and AKI therapeutics. He has published over 100 peer-reviewed articles and book chapters on AKI and the care of patients in with kidney injury in the ICU.
Alex Zarbock, MD
Dr. Zarbock is a Clinician Scientist and the Director and Chair of the Department of Anesthesiology and Critical Care Medicine, at the University of Münster, Germany. He acquired training at the University of Münster (Anesthesiology and Critical Care Medicine). Dr. Zarbock is supported by the German Research Foundation. His research interests span various aspects of Critical Care Medicine, but center in critical care nephrology (renal replacement therapy), sepsis and organ protection. Dr. Zarbock’s current projects include measures to avoid acute kidney injury after surgery and the timing of renal replacement therapy in critically ill patients with acute kidney injury. He is also author and co-author of over 140 scientific articles and book chapters.
12:30-2:00
Lunch Symposium I2. Additional Industry Session Offered (Non-CME)
TBA
SESSION III: EMERGING CONCEPTS IN AKI AND RRT
Plenary 4 MINI SYMPOSIA
Novel Strategies in AKI Management
2:00-3:45
Andrew Lewington, MD
Dr Andrew Lewington studied medicine as an undergraduate in London before pursuing a career in renal medicine. He studied in Leicester UK and Washington University USA where he worked in Mark Hammermann's laboratory investigating the molecular mechanisms underlying ischaemic acute kidney injury.Dr Lewington was appointed consultant renal physician/honorary senior lecturer at Leeds Teaching Hospitals in 2004. He works as an NHS clinician providing a specialist renal opinion on acutely ill patients on the ICU across Leeds. He was an expert adviser on the UK NCEPOD adding insult to injury AKI study, working from his position on the Renal Association executive committee to improve the care that patients who develop AKI receive. He is the lead author of the 5th Renal Association AKI clinical practice guidelines. During his time in Leeds he has developed collaborative research with an internationally recognised proteomics group. He currently has a nephrology fellow investigating potential proteomic biomarkers of kidney dysfunction in the early phase following kidney transplantation. He is Clinical Sub Dean for the Leeds Teaching Hospitals and is heavily involved in the delivery of undergraduate medical education at the University of Leeds.
Li Yang, MD
Dr. Yang is an Associate Professor of Medicine in the Renal Division of Peking University First Hospital and Associate Director in the Institute of Nephrology at Peking University, where she directs clinical acute kidney injury, renal pathology, and basic research in nephrology. She is committee member of the International Society of Nephrology Commission on Acute Renal Failure. She received the M.D. degree from Peking University in 2001, and has been on the faculty at Peking University First Hospital since 2001. She was a Research Fellow, granted by the International Society of Nephrology, in the renal division of Brigham and Womens Hospital at Harvard Medical School, from 2007-2010. Her research interests are in the fields of acute kidney injury, drug associated kidney diseases and renal pathology.
2:00-2:15
Renal Recovery Patterns after AKI: Do they Matter?
Room: Coronado Ballroom
Edward Siew, MD, MSCI
Dr. Edward D. Siew is an Assistant Professor of Medicine at the Vanderbilt University School of Medicine in Nashville, TN within the Division of Nephrology and Hypertension. Dr. Siew received his medical degree at the University of Chicago Pritzker School of Medicine and completed his residency in internal medicine at The University of California, San Francisco. He also completed fellowships in Critical Care Medicine and the University of Pittsburgh School of Medicine and Nephrology at Vanderbilt University School of Medicine. Dr. Siew is also a graduate of the Masters of Science in Clinical Investigation at Vanderbilt whose research program is focused on improving the care of patients with acute kidney injury (AKI). Ongoing projects include using novel biomarkers of injury to refine the diagnosis of AKI and provide better prognostic information, leveraging the electronic health record to better examine healthcare delivery to patients who experience AKI, and improving understanding of the long-term impact of this disease, including identifying mechanisms that contribute to progressive loss of kidney function and cardiovascular disease in this population. Dr. Siew currently also serves as a co-investigator of the NIH-sponsored Assessment and Serial Evaluation of the Subsequent Sequelae of Acute Kidney Injury (ASSESS-AKI) study, a prospective multi-center study examining the long-term natural history of AKI.
2:15-2:30
Therapies for Preeclampsia: Addition vs Subtraction
Room: Coronado Ballroom
Ravi Thadhani, MD
2:30-2:45
AKI in Stem Cell Transplantation
Room: Coronado Ballroom
Mitchell Rosner, MD
Dr. Rosner is currently the Henry B. Mulholland Professor of Medicine at the University of Virginia School of Medicine as well as the Chairman of the Department of Medicine. Dr. Rosner serves on the executive committee of training program directors for the American Society of Nephrology. His research interests include: sodium and water metabolism and acute kidney injury. He is a fellow of the American Society of Nephrology and a fellow of the American College of Physicians
2:45-3:00
Acute Kidney Disease: Is it Useful in Describing Renal Outcomes?
Room: Coronado Ballroom
Nick Selby, MD
Dr Selby studied medicine at the University of Nottingham, graduating in 1998, and after completing post-graduate training in the East Midlands was appointed a full-time NHS consultant nephrologist at the Royal Derby Hospital in 2009. In 2015 he was appointed Associate Professor of Nephrology at the University of Nottingham, based in the Centre for Kidney Research and Innovation (www.nottingham.ac.uk/research/groups/renal), Royal Derby Hospital Postgraduate Medical School.
Dr. Selby is a clinical academic with primary interests in Acute Kidney Injury (AKI), Magnetic Resonance Imaging (MRI) of the kidney and the haemodynamic consequences of dialysis. He led the development of one of the first e-alert systems for AKI in the UK and is CI on several investigator-instigated studies in these areas. Since 2011 Dr Selby has been awarded peer reviewed grant funding from MRC, the Health Foundation, Kidney Research UK and British Renal Society. He has published over 60 peer-reviewed articles. Dr Selby has several national AKI roles, including leadership of the AKI Clinical Study Group that sits within the UK Kidney Research Consortium, the co-chair of the UK Renal Imaging Network and programme board of the NHS England ‘Think Kidneys’ programme.
3:00-3:15
The Kidney and the Mission to Mars
Room: Coronado Ballroom
Claudio Ronco, MD
Actual Position:
Dr. Claudio Ronco
Director
Department of Nephrology
St. Bortolo Hospital
Viale Rodolfi 16
I-36100 Vicenza
Italy
Name: Claudio Ronco
Date of birth: July 12, 1951
Education: High School Diploma at Vicenza Classic Lyceum A.Pigafetta in 1970 with the score: 45/60. Dr. Ronco Graduated in Medicine at University of Padua in 1976 with the score 110/110 and merit debating an experimental thesis on title Aspects of the Nitrogen metabolism in the nephrotic syndrome.
From 1973 to 1976 has been intern at Institute of Clinical Internal Medicine I^ of the University of Padua, directed by Prof. E. Fiaschi, in the Nephrology Department II, under the supervision of the Prof. G. Maschio.
Postgraduate training: From July 1976 to November 1977 he has been internal resident at the Division of Internal Medicine of the St. Bortolo Hospital in Vicenza, directed by Prof. D. Cor.
In 1979 he has achieved the Specialization Diploma on Medical Nephrology at The postgraduate school of internal medicine of the University of Padua, with the score 70/70 debating a thesis on the new methodologies for the measurement of the urinary bicarbonate
In 1989 he has achieved the Diploma of Specialization in Pediatric Nephrology at University of Naples.
1982: Visiting Fellow at the Mount Sinai Hospital in New York, Department of Internal medicine, Nephrology Division, for four months. He carried out studies on hemofiltration and glomerular filtration with J.P. Bosh, S. Glabman and M. Levitt.
1984: Visiting Physician at the Mount Sinai Hospital In New York for two weeks and at VA Hospital in Los Angeles for two weeks.
1985: Visiting professor at the Nephrology Division of the George Washington University Hospital, Washington DC, and NIH at National Naval Medical Center of Bethesda for three months.
1988: Visiting professor at the Renal and Hypertension Division of George Washington University for three months.
1991: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
1995: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
Teaching acitivity and Academic Qualifications: From 1978 to 1984 he has been in charge of the teaching program of Nephrology and Dialysis at Professional Nursing School in Vicenza.
During the academic years 1989-01 he has been in charge of teaching Dialytic therapy at Specialization School in Medical Nephrology of Padua University where he holds a post of Professor of Nephrology in charge of the teaching program concerning Hemodialysis and renal replacement therapies in critically ill patients.
October 1999-December 2000: Professor of Medicine at Albert Einstein College of Medicine and Director of the Renal laboratory at the Beth israel Medical Center in New York.
In the last ten years Professor Ronco was asked to deliver lectures and seminars in several Universities.
He has delivered in meetings and seminars more than 300 lectures and presentations.
In 1982 he introduced in Italy the use of continuous hemofiltration and in 1986 he published the first series of neonates treated with arteriovenous hemofiltration.
In 1985 He contributed to the introduction in Europe of high flux dialysis and derived therapies. He also established the dangerous effect of backfiltration in a contaminated dialysis fluid condition.
He has conducted a series of clinical and experimental researches in the following fields:
- Kinetics of fluid and solute removal in peritoneal dialysis and hemodialysis
- Treatment of Acute renal failure with intermittent and continuous therapies
- Renal replacement therapy in the neonate
- Development of new treatment modalities for acute and chronic renal failure.
- Studies on biomaterials
- Studies on glomerular filtration in humans and renal functional reserve
- Renal physiology in pregnancy
- Hydraulics and flow dynamics in the extracorporeal circulation
- Adequacy of dialysis
- Acid-Base Balance in uremia and dialysis
- Acute renal failure and Critical Care Nephrology
Professional employement and Hospital appointments:
Assistant of clinical nephrology from 1977 to 1984 at Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Associate of clinical nephrology from 1984 at Department of Nephrology , St. Bortolo Hospital, Vicenza, Italy.
From 1984 he is director of the hemodialysis and peritoneal dialysis center of the Department of Nephrology at St. Bortolo Hospital, Vicenza, Italy.
From October 25, 1999 to December 1st 2000 Dr. Ronco has been Director of the research laboratory of Hemodialysis at the Beth Israel Medical center of New York and Visiting Professor of Medicine at the Albert Einstein College of Medicine of new York
Today Dr. Ronco is director of the Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Board certification: In 1989 he has achieved in Rome, the National License for Nephrology Chair and Directional Functions, with the score 94/100.
Professional Society Membership: He is mamber of the council of several scientific societies and he is editor in chief of the international journal of artificial organs and contributions to nephrology.
Awards and honors:
1983 Schwartz Award, for the best paper of the year at St. Bortolo Hospital.
1984 G.F. Volpato Grant for the best research project on acute renal failure in Italy
1989 Best paper Prize at the Italian Society of nephrology meeting.
1991 ESAO RESEARCH AWARD for the best paper presented at the European Society for Artificial Organs.
1996 Arturo Borsatti Award of Padova University as a best nephrologist of the year.
2004 Lifetime achievement award
Other professional activities: He has organized several congresses and meetings in the area of nephrology and Intensive care from 1982 to today.
He is member of several advisory groups for clinical trials and dialysis research.
Lectures and publications: Dr. Ronco has coauthored 560 papers, 36 book chapters, 26 books, 7 monographic journal issues and has delivered more than 300 lectures in international meetings and universities. His personal impact factor calculated at december 2002 is 391.
3:15-3:30
Multidisciplinary Care: Why AKI Patients Need All of Us?
Room: Coronado Ballroom
Azra Bihorac, MD, MS, FCCM, FASN
Azra Bihorac leads large multidisciplinary research partnership PrismaP (Precision and Intelligence in Medicine) that brings together experts in the field of predictive modeling, medical informatics and autonomic networks. Her team is developing machine learning and informatics tool for real-time risk stratification and annotation of hospital-acquired complications that would allow management to be tailored to a patients’ “personal clinical profile” using clinical data gathered during routine care.
3:30-3:45
AKI Subphenotypes in Acute Heart Failure
Room: Coronado Ballroom
Patrick Murray, MD
Patrick Murray is Professor of Clinical Pharmacology in University College Dublin, and a consultant physician (clinical pharmacologist & nephrologist) at the Mater Misericordiae University Hospital, Dublin, Ireland.
He received his medical education at University College Dublin, Ireland.
Following his internship at the Mater Misericordiae University Hospital in Dublin, he completed a residency in internal medicine at Hennepin County Medical Center in Minneapolis, Minnesota, USA.
He completed fellowship training programs in nephrology, critical care medicine, and clinical pharmacology at the University Of Chicago Hospitals in Chicago, Illinois, USA.
He is board-certified in nephrology, critical care medicine, and clinical pharmacology.
He practiced as an intensivist, nephrologist, and clinical pharmacologist at the University of Chicago Hospitals from 1996–2008, serving as the fellowship training program director in nephrology, also directing the Acute Dialysis Service.
He has a longstanding interest in research and education to improve the prevention, diagnosis, and therapy of acute kidney injury and nephrotoxicity, and the pharmacotherapy of patients with kidney disease. He is a member of several international consensus groups that have produced guidelines for research and practice in the field of acute kidney injury (ADQI, AKIN, KDOQI).
Since 2008, he has been the Professor of Clinical Pharmacology at University College Dublin, and a Consultant in Nephrology & Clinical Pharmacology at the Mater Misericordiae University Hospital. He is Chair of the Mater Misericordiae University Hospital Drugs & Therapeutics Committee. He is the Clinical Director of the UCD-Mater Clinical Research Centre. In 2011, he was appointed Associate Dean for International Affairs in the UCD School of Medicine and Medical Science. In 2012, he was appointed Director of the Dublin Centre for Clinical Research (DCCR) Consortium Network, and also Clinical Director of the Irish Clinical Research Infrastructure Network (ICRIN). From December 2012 until July 2018, he served as the Dean and Head of the School of Medicine at UCD.
Plenary 5 MINI SYMPOSIA
Challenges and Controversies in Renal Support and CRRT
4:15-6:00
David Askenazi, MD, MSPH
Dr. Askenazi is the Medical Director of the Pediatric and Infant Center for Acute Nephrology (PICAN), whose mission is to impove the outcomes of infants and children at risk for acute kidney disease by performing excellent comprehensive multi-disciplinary care, research and education. Dr. Askenazi's research interest include: a) the role that acute kidney injury (AKI) has on short and long-term outcomes in neonates and pediatric patients, b) testing therapies to improve the short and long-term outcomes of neonates and pediatric patients with AKI, and c) improving the definition of neonatal AKI using urinary and serum biomarkers of AKI.
Ashita Tolwani, MD
Ashita Tolwani, MD (MSc),Professor of Medicine. Dr. Tolwani is also the Associate Director for the Nephrology fellowship program at UAB and Associate Director of ICU Nephrology at UAB. Dr. Tolwani completed her nephrology fellowship at UAB and joined the Division as a faculty member. She received a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health. Her interests are in clinical outcomes research in nephrology, specifically with issues concerning continuous renal replacement therapy in patients with acute kidney injury in the intensive care unit. Her other research interests include the use of anticoagulants during continuous renal replacement therapy.
4:15-4:30
Deresuscitation in Patients with AKI
Room: Coronado Ballroom
Ron Wald, MD
Ron Wald is a nephrologist at St. Michael's Hospital in Toronto where he also serves as the Medical Director of the hospital's Hemodialysis Program. He is an Associate Professor of Medicine at the University of Toronto. His primary research interest is in critical care nephrology and he has been involved in several clinical trials in this area. He is currently co-leading an international randomized controlled trial on the timing of renal replacement therapy in acute kidney injury. Ron's other interests are volume optimization in patients with AKI and the post-discharge care provided to AKI survivors.
4:30-4:45
The Wait and See Approach for RRT: Does it Work?
Room: Coronado Ballroom
Ravindra Mehta, MBBS, MD, DM, FACP
Dr. Mehta is Professor of Medicine in the Division of Nephrology and Associate Chair for Clinical Affairs in the Department of Medicine at the University of California, San Diego (UCSD) where he directs the Clinical nephrology and dialysis programs. He is also the Chair of the International Society of Nephrology Commission on Acute Renal Failure, founding member of the Acute Dialysis Quality Initiative. He received the M.B.B.S. degree (1976) from the Government Medical School in Amritsar, India, and the M.D. (1979) and D.M. (1981) degrees from the Post Graduate Institute of Medical Education and Research in Chandigarh, India. He subsequently completed a nephrology fellowship at the University of Rochester in Rochester New York and obtained his boards in internal medicine (1986) and Nephrology (1988). He has been on the faculty at San Diego since 1988. His reserach interests are in the field of acute renal failure and he has directed several clinical studies in the management of patients with ARF including comparing different dialytic modalities, conducting large multicenter observational studies of ARF with the PICARD group, evaluating different predictive models for outcomes in ARF, investigating the role of cytokine removal by dialysis membranes in sepsis and ARF, and evaluating techniques for determining the amount of excess fluid in dialysis patients.
4:45-5:00
The Economic Consequences of AKI
Room: Coronado Ballroom
Glenn Chertow, MD
Glenn Chertow, MD, MPH, is the Norman S. Coplon/Satellite Healthcare Professor of Medicine and Chief, Division of Nephrology at Stanford University School of Medicine. His research interests are focused on epidemiology, health services research, and clinical trials in acute and chronic kidney disease. Dr. Chertow is involved in research sponsored by the National Institutes of Health and has written numerous papers on end-stage renal disease, acute renal failure, nutrition, mineral metabolism, and the costs and outcomes of dialysis therapy. He is Co-Editor of Brenner and Rector's The Kidney and serves on the editorial boards of the Journal of the American Society of Nephrology (JASN). Dr. Chertow has designed and/or monitored several NIH- and industry-sponsored cohort studies and clinical trials in kidney disease, including CRIC, ATN, FHN, DAC, SPRINT, TREAT, ADVANCE and EVOLVE. In addition to his research and teaching activities, Dr. Chertow has an active clinical practice, focused on inpatient and outpatient nephrology care.
5:00-5:30
SPECIAL LECTURE
Perioperative AKI: ighlights from ADQI 24
Room: Coronado Ballroom
Lui Forni, MD
John Prowle, MA, MSc, MD, FRCP
Dr Prowle is a Senior Clinical Lecturer in Intensive Care Medicine within the Critical Care and Perioperative Medicine Research Group at Barts and the London School of Medicine and Dentistry, Queen Mary University of London and is an Honorary Consultant Physician in Intensive Care Medicine and Nephrology at the Royal London Hospital, Barts Health NHS Trust, London, UK. He graduated in medicine from the University of Cambridge in 1999 and undertook Doctoral Research under the supervision of Prof Rinaldo Bellomo in Melbourne, Australia leading to the award of his research doctorate in 2013. Dr Prowle’s academic interests include the Pathogenesis, Diagnosis and Treatment and Outcomes of Acute Kidney Injury, Continuous Renal Replacement Therapies in the ICU, Fluid Therapy and Medical Complications of Major Surgery. Since 2009 he has co-authored over 80 peer-reviewed publications and book chapters, including chapters related to Acute Kidney Injury in the latest editions of the Oxford Textbook of Clinical Nephrology and the Oxford Textbook of Critical Care.
5:30-6:00
VIEWPOINT
Management of AKI: The Patient's Perspective
Room: Coronado Ballroom
Marla Levy, Patient Advocate
Marla Levy will be sharing her journey through four open heart surgeries, and six days on life support which caused AKI and then CKD. Since her recent recovery, she has been passionate about partnering with the medical community in hopes to shine light on how she experienced the continuum of care in both the acute care setting and also in the outpatient dialysis center. Hearing Marla’s story allows others to see the world through a patient’s eyes. It is a completely different perspective which cannot help but evoke new questions on how nephrology patients are treated today, and how to help them avoid the unnecessary pitfalls they continue to fall into. Her honesty, candor and humor are both refreshing and educational.
6:00
Adjourn
Free Evening
Room: Coronado Ballroom
Thursday Morning, February 27
7:00am-1:00pm
Conference Registration Open
MEET THE EXPERTS BREAKFASTS (elective events)
6:45-8:00
ME5 MEET THE EXPERT
When do I Start RRT in My ICU
Sean Bagshaw, MD, MSc, FRCPC
Dr. Bagshaw is a Clinician Scientist and Assistant Professor in the Division of Critical Care Medicine, at the University of Alberta in Edmonton, Alberta, Canada. He acquired training at the University of Calgary (Internal Medicine, Critical Care Medicine, Masters of Science Epidemiology) prior to completing a critical care nephrology fellowship in the Department of Intensive Care Medicine, at the Austin Hospital in Melbourne, Australia.
Dr. Bagshaw is supported by a Canada Research Chair in Critical Care Nephrology and a Clinical Investigator Award from Alberta Innovates - Health Solutions. Dr. Bagshaw's main research interests have focused on the clinical, epidemiological and translational issues related to acute kidney injury and the application of extracorporeal blood purification in critically ill patients. Dr. Bagshaw's current projects include diuretic therapy in early acute kidney injury and factors related with the initiation of renal support in critically ill patients. He has published over 100 peer-reviewed papers, numerous book chapters, and peer-reviewed for over 20 medical journals.
Dr. Bagshaw is a member of several organizations including the Canadian Critical Care Society, Canadian Critical Care Trials Group, Australia New Zealand Intensive Care Society, and the Acute Kidney Injury Network, and the Acute Dialysis Quality Initiative.
Claudio Ronco, MD
Actual Position:
Dr. Claudio Ronco
Director
Department of Nephrology
St. Bortolo Hospital
Viale Rodolfi 16
I-36100 Vicenza
Italy
Name: Claudio Ronco
Date of birth: July 12, 1951
Education: High School Diploma at Vicenza Classic Lyceum A.Pigafetta in 1970 with the score: 45/60. Dr. Ronco Graduated in Medicine at University of Padua in 1976 with the score 110/110 and merit debating an experimental thesis on title Aspects of the Nitrogen metabolism in the nephrotic syndrome.
From 1973 to 1976 has been intern at Institute of Clinical Internal Medicine I^ of the University of Padua, directed by Prof. E. Fiaschi, in the Nephrology Department II, under the supervision of the Prof. G. Maschio.
Postgraduate training: From July 1976 to November 1977 he has been internal resident at the Division of Internal Medicine of the St. Bortolo Hospital in Vicenza, directed by Prof. D. Cor.
In 1979 he has achieved the Specialization Diploma on Medical Nephrology at The postgraduate school of internal medicine of the University of Padua, with the score 70/70 debating a thesis on the new methodologies for the measurement of the urinary bicarbonate
In 1989 he has achieved the Diploma of Specialization in Pediatric Nephrology at University of Naples.
1982: Visiting Fellow at the Mount Sinai Hospital in New York, Department of Internal medicine, Nephrology Division, for four months. He carried out studies on hemofiltration and glomerular filtration with J.P. Bosh, S. Glabman and M. Levitt.
1984: Visiting Physician at the Mount Sinai Hospital In New York for two weeks and at VA Hospital in Los Angeles for two weeks.
1985: Visiting professor at the Nephrology Division of the George Washington University Hospital, Washington DC, and NIH at National Naval Medical Center of Bethesda for three months.
1988: Visiting professor at the Renal and Hypertension Division of George Washington University for three months.
1991: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
1995: Visiting Professor at the Renal and Hypertension Division of George Washington University for three months.
Teaching acitivity and Academic Qualifications: From 1978 to 1984 he has been in charge of the teaching program of Nephrology and Dialysis at Professional Nursing School in Vicenza.
During the academic years 1989-01 he has been in charge of teaching Dialytic therapy at Specialization School in Medical Nephrology of Padua University where he holds a post of Professor of Nephrology in charge of the teaching program concerning Hemodialysis and renal replacement therapies in critically ill patients.
October 1999-December 2000: Professor of Medicine at Albert Einstein College of Medicine and Director of the Renal laboratory at the Beth israel Medical Center in New York.
In the last ten years Professor Ronco was asked to deliver lectures and seminars in several Universities.
He has delivered in meetings and seminars more than 300 lectures and presentations.
In 1982 he introduced in Italy the use of continuous hemofiltration and in 1986 he published the first series of neonates treated with arteriovenous hemofiltration.
In 1985 He contributed to the introduction in Europe of high flux dialysis and derived therapies. He also established the dangerous effect of backfiltration in a contaminated dialysis fluid condition.
He has conducted a series of clinical and experimental researches in the following fields:
- Kinetics of fluid and solute removal in peritoneal dialysis and hemodialysis
- Treatment of Acute renal failure with intermittent and continuous therapies
- Renal replacement therapy in the neonate
- Development of new treatment modalities for acute and chronic renal failure.
- Studies on biomaterials
- Studies on glomerular filtration in humans and renal functional reserve
- Renal physiology in pregnancy
- Hydraulics and flow dynamics in the extracorporeal circulation
- Adequacy of dialysis
- Acid-Base Balance in uremia and dialysis
- Acute renal failure and Critical Care Nephrology
Professional employement and Hospital appointments:
Assistant of clinical nephrology from 1977 to 1984 at Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Associate of clinical nephrology from 1984 at Department of Nephrology , St. Bortolo Hospital, Vicenza, Italy.
From 1984 he is director of the hemodialysis and peritoneal dialysis center of the Department of Nephrology at St. Bortolo Hospital, Vicenza, Italy.
From October 25, 1999 to December 1st 2000 Dr. Ronco has been Director of the research laboratory of Hemodialysis at the Beth Israel Medical center of New York and Visiting Professor of Medicine at the Albert Einstein College of Medicine of new York
Today Dr. Ronco is director of the Nephrology Division in St. Bortolo Hospital, Vicenza, Italy.
Board certification: In 1989 he has achieved in Rome, the National License for Nephrology Chair and Directional Functions, with the score 94/100.
Professional Society Membership: He is mamber of the council of several scientific societies and he is editor in chief of the international journal of artificial organs and contributions to nephrology.
Awards and honors:
1983 Schwartz Award, for the best paper of the year at St. Bortolo Hospital.
1984 G.F. Volpato Grant for the best research project on acute renal failure in Italy
1989 Best paper Prize at the Italian Society of nephrology meeting.
1991 ESAO RESEARCH AWARD for the best paper presented at the European Society for Artificial Organs.
1996 Arturo Borsatti Award of Padova University as a best nephrologist of the year.
2004 Lifetime achievement award
Other professional activities: He has organized several congresses and meetings in the area of nephrology and Intensive care from 1982 to today.
He is member of several advisory groups for clinical trials and dialysis research.
Lectures and publications: Dr. Ronco has coauthored 560 papers, 36 book chapters, 26 books, 7 monographic journal issues and has delivered more than 300 lectures in international meetings and universities. His personal impact factor calculated at december 2002 is 391.
6:45-8:00
ME6 MEET THE EXPERT
When and How do I use Diuretics and Aquaretics
Lui Forni, MD
Matthieu LeGrand, MD
Pr Matthieu Legrand is Professor of Anesthesiology and Critical care medicine. He holds a PhD in physiology. He Works in the Department of anesthesiology, Critical care and burn unit of St-Louis hospital, university Paris Diderot, France. He has carried preclinical and clinical research in the field of critical care medicine with a special interest in critical care nephrology, sepsis and in burn critical care. He has served as a reviewer for several peer-review journals and expert in the field of critical care for several commitees and task forces.
Breakfast Symposia
6:45-8:00
6:45-8:00
I3. Additional Industry Breakfast Session (Non-CME)
TBA
SESSION IV: IMPROVING OUTCOMES IN AKI
Plenary 6 MINI SYMPOSIA
Global Burden of AKI
8:00-10:30
Javier Neyra
Eisei Noiri, MD, PhD, FASN
Eisei NOIRI graduated from Hamamatsu University School of Medicine (HUSM) and received PhD at The University of Tokyo under Prof. Kiyoshi Kurokawa. He spent three years in SUNY Stony Brook and BNL under Prof. Michael Goligorsky. He is one of the chief researchers in Division of Nephrology and head of Department of Hemodialysis and Apheresis in The University of Tokyo Hospital. His research interests are broad from basic sciences in AKI pathophysiology, clinical applicability of biomarkers, epidemiology of CRRT, theoretical consideration to CRRT and apheresis therapy, and more.
8:00-8:15
AKI in CKD: Aftershocks
Room: Coronado Ballroom
Michael Zappitelli, MD, MSc
Michael Zappitelli, MD, MSc practices Pediatric Nephrology, currently Assistant Professor in Pediatrics and Director of the Extracorporeal Blood Therapy and Peritoneal Dialysis Program in Montreal Canada. After training in Pediatric Nephrology and in Epidemiology and Biostatistics at McGill University, Montreal, Canada (2003-2005), he completed a research fellowship in Pediatric Critical Care Nephrology at Texas Children's Hospital, Baylor College of Medicine, Houston, Texas (2005-2007). He has performed research in estimating glomerular filtration rate in children, using serum creatinine and cystatin C-based equations, has published manuscripts on the use of early biomarkers of acute kidney injury in children and on the validation of a pediatric definition for acute kidney injury and has written several book chapters on diagnosis and management of pediatric acute kidney injury. He also performed research in the area of nutritional provision in children treated with continuous renal replacement therapy. Currently, he continues to perform research in early biomarkers of acute kidney injury in children and on epidemiology and definition of pediatric acute kidney injury.
8:15-8:30
AKI and the Global Burden of Disease
Room: Coronado Ballroom
Jorge Cerda, MD, MS, FACP, FASN
Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY
Clinical Associate Professor of Medicine, Albany Medical College, Albany NY
Fulbright Scholar, 1980
Fellow, American College of Physicians
Fellow, American Society of Nephrology
Organizing Committee, International Conference AKI & CRRT
AKI Advisory Group, American Society of Nephrology
AKI Committee, and "0by25" Initiative, International Society of Nephrology
Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease
Associate Editor, Blood Purification and Kidney International Reports
Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases
Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world
8:30-8:45
Challenges and Progress of AKD Care
Room: Coronado Ballroom
Vincent Wu, MD, PhD
Vin-Cent actively involved in the analysis of a database of acute kidney injury in the National Taiwan University Study Group on Acute Renal Failure (NSARF) and Consortium for Acute Kidney Injury and Renal Diseases (CAKs) strive to advance high-quality care in acute kidney injury (AKI) and aspires to plunge the worldwide increasing prevalence of chronic kidney disease (CKD) from the perspective of AKI-CKD transition.
8:45-9:00
AKI Secondary to Overdose
Room: Coronado Ballroom
Andrew Lewington, MD
Dr Andrew Lewington studied medicine as an undergraduate in London before pursuing a career in renal medicine. He studied in Leicester UK and Washington University USA where he worked in Mark Hammermann's laboratory investigating the molecular mechanisms underlying ischaemic acute kidney injury.Dr Lewington was appointed consultant renal physician/honorary senior lecturer at Leeds Teaching Hospitals in 2004. He works as an NHS clinician providing a specialist renal opinion on acutely ill patients on the ICU across Leeds. He was an expert adviser on the UK NCEPOD adding insult to injury AKI study, working from his position on the Renal Association executive committee to improve the care that patients who develop AKI receive. He is the lead author of the 5th Renal Association AKI clinical practice guidelines. During his time in Leeds he has developed collaborative research with an internationally recognised proteomics group. He currently has a nephrology fellow investigating potential proteomic biomarkers of kidney dysfunction in the early phase following kidney transplantation. He is Clinical Sub Dean for the Leeds Teaching Hospitals and is heavily involved in the delivery of undergraduate medical education at the University of Leeds.
9:00-9:15
AKI in Southeast Asia: Long Term Outcomes
Room: Coronado Ballroom
Nattachai Srisawat, MD, PhD
Current position
- Director of Excellence Center for Critical Care Nephrology, King Chulalongkorn Memorial Hospital, Thai Red Cross, Bangkok, Thailand
- Division of Nephrology, Department of Medicine, Chulalongkorn University, Bangkok, Thailand
- Collaborating CRISMA faculty member Department of Critical Care Medicine, University of Pittsburgh School of Medicine, USA
My background:
After finishing Nephrology training from Thailand in 2007, He became the part of CRISMA research fellow for 2 years and clinical fellow of Critical Care Medicine for 1 year under mentorship by Professor John A Kellum at Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pennsylvania, USA. He received European Diploma of Intensive Care Medicine in 2012. His main research focused in AKI epidemiology in resource limited setting, novel biomarkers of AKI, and tropical infections causing AKI such as leptospirosis, and dengue infection.
9:15-9:30
Temporal Change in AKI/CRRT in The Japanese Experience
Room: Coronado Ballroom
Kent Doi, MD
Kent Doi, M.D., Ph.D. is Assistant Professor of Medicine in the division of Emergency and Critical Care Medicine at The University of Tokyo, Japan. He received his M.D. and Ph.D., and residency training at the University of Tokyo Hospital followed by research nephrology training at NIH/NIDDK (2005-2007). At the University of Tokyo Dr. Doi is a clinical and basic research investigator. His research interests include acute kidney injury and sepsis. Current research involves AKI biomarker development and clarification of pathophysiology of sepsis-induced AKI. He is also working for the renal support therapy in the ICU. Dr. Doi is Fellow of the American Society of Nephrology (FASN) and the Japanese Society of Internal Medicine (FJSIM), Councilor and Board Certified Nephrologist of the Japanese Society of Nephrology, Board Certified Senior Member of the Japanese Society for Dialysis Therapy, and Councilor of the Japanese Society for Blood Purification in Critical Care.
9:30-9:45
AWARE - More Than Just AKI Awareness?
Room: Coronado Ballroom
Stuart Goldstein, MD
Dr. Goldstein serves as Director for the Center for Acute Care Nephrology (CACN) at Cincinnati Children's Hospital Medical Center. The CACN's mission is to coordinate all AKI related clinical, research and outcomes efforts at CCHMC and to function as a nexus for coordinating multi-center pediatric AKI research. Dr. Goldstein is the Founder and Principal Investigator of the Prospective Pediatric AKI Research Group (www.ppaki.org), a 50 center international pediatric acute care nephrology research consortium that will focuses on pediatric AKI epidemiology, interventional trials, device evaluation and genetic studies. Dr. Goldstein is also the program director for the only Pediatric Acute Care Nephrology fellowship in the United States.
9:45-10:00
CKD of Unknown Origin: The Case of Repeated AKI Episodes?
Room: Coronado Ballroom
Magdalena Madero, MD
Magdalena Madero, MD, is the Chief of Nephrology at the Instituto Nacional de Cardiología in Mexico City. She was trained in Internal Medicine at St Elisabeth’s Medical Center in Boston, MA, and then underwent her nephrology training at Tufts Medical Center also in Boston, MA. She went back to Mexico City in 2007 where she joined the nephrology staff at Instituto Nacional de Cardilogía and became the Head of the Nephrology Division in 2011.
Dr. Madero's research interests include CKD complications and outcomes in addition to the metabolic and renal effects of fructose and uric acid and more recently is interested in CKD of unknown origin. As part of her educational activities she runs one of the largest renal fellowship programs in the country (affiliated to the main National Mexican University [UNAM]) in addition to teaching the nephrology course at the undergraduate Panamerican University medical school. She is the past president of Mexican Institute of Renal Research (IMIN) and currently acts as the International Editor for the American Journal of Kidney Diseases. She has recently joined the KDIGO Executive Committee.
10:00-10:15
AKI After Civilian Trauma
Room: Coronado Ballroom
Emmanuel Burdmann, MD, PhD
Dr. Emmanuel A. Burdmann attended medical school at the University of So Paulo Medical School, So Paulo, Brazil and completed residency in Internal Medicine and fellowships in Nephrology at Hospital das Clnicas, University of So Paulo Medical School, So Paulo, Brazil. He received his Doctorate in Nephrology from the University of So Paulo Medical School and did a post-doc research fellowship at the Nephrology Division of the Oregon Health Sciences University, Portland, Oregon. Dr. Burdmann is the past-president of the Latin-American Society of Nephrology and Hypertension and is currently the president of the Brazilian Society of Nephrology. His current academic position is as Associate Professor of Nephrology at the So Jos do Rio Preto Medical School, where he is responsible for the care of the AKI patients and for the Post-Graduation Program. Dr Burdmann serves as Associate-Editor in the Clinical Journal of the American Society of Nephrology and in Nephrology, Dialysis, and Transplantation. He is member of AKIN and KDIGO. His research interests centers on acute kidney injury and drugs and animal venoms nephrotoxicity.
10:15-10:30
AKD in the Community: Detection and Prevention
Room: Coronado Ballroom
Li Yang, MD
Dr. Yang is an Associate Professor of Medicine in the Renal Division of Peking University First Hospital and Associate Director in the Institute of Nephrology at Peking University, where she directs clinical acute kidney injury, renal pathology, and basic research in nephrology. She is committee member of the International Society of Nephrology Commission on Acute Renal Failure. She received the M.D. degree from Peking University in 2001, and has been on the faculty at Peking University First Hospital since 2001. She was a Research Fellow, granted by the International Society of Nephrology, in the renal division of Brigham and Womens Hospital at Harvard Medical School, from 2007-2010. Her research interests are in the fields of acute kidney injury, drug associated kidney diseases and renal pathology.
SESSION V: FUTURE TRENDS IN CRRT AND CRITICAL CARE
Plenary 7 MINI SYMPOSIA
Emerging Strategies in AKI and Extracorporeal Support
11:00-1:00
Jorge Cerda, MD, MS, FACP, FASN
Chief, Dept of Medicine, St Peter's Healthcare, Albany, NY
Clinical Associate Professor of Medicine, Albany Medical College, Albany NY
Fulbright Scholar, 1980
Fellow, American College of Physicians
Fellow, American Society of Nephrology
Organizing Committee, International Conference AKI & CRRT
AKI Advisory Group, American Society of Nephrology
AKI Committee, and "0by25" Initiative, International Society of Nephrology
Member, Acute Dialysis Quality Initiative (ADQI); Acute Kidney International Network (AKIN), Global Burden of Disease
Associate Editor, Blood Purification and Kidney International Reports
Editorial Board, American Journal of Kidney Diseases, NephSAP, American Board of Internal Medicine. Kidney International, Lancet, American Journal Kidney Diseases
Main research interests and publications: Acute Renal Injury, CRRT, AKI around the world
Vincent Wu, MD, PhD
Vin-Cent actively involved in the analysis of a database of acute kidney injury in the National Taiwan University Study Group on Acute Renal Failure (NSARF) and Consortium for Acute Kidney Injury and Renal Diseases (CAKs) strive to advance high-quality care in acute kidney injury (AKI) and aspires to plunge the worldwide increasing prevalence of chronic kidney disease (CKD) from the perspective of AKI-CKD transition.
11:00-11:15
Apheresis Applications in the ICU
Room: Coronado Ballroom
David Ward, MD, FRCP
David Ward trained as a nephrologist in his native Scotland and then did a second fellowship in renal immunopathology at Scripps Research in San Diego. He joined the Division of Nephrology at UCSD in 1977, and throughout has been one of its most active academic clinicians. He directed a laboratory research program in experimental glomerular pathology for several years, and for two decades was chief of clinical nephrology and director of dialysis. He founded UCSD’s therapeutic apheresis program in 1982 and was its director for 35 years. At different times he served as Assistant Dean of Clinical Affairs, Chief of Staff of the Hospital, and Chairman of the UCSD Medical Group. His other contributions include the invention of citrate-anticoagulated CRRT and innovations in hemodialysis technology and apheresis. He has published in all these areas and authored chapters in several standard textbooks. Since his semi-retirement in July 2017, he remains in part-time practice in apheresis and transplantation medicine, and consults on complex immunological and glomerular disease cases. He continues to teach on these topics and is a frequent invited speaker at national meetings.
11:15-11:30
Peritoneal Dialysis for AKI: The Forgotten Modality
Room: Coronado Ballroom
Rajasekara Chakravarthi, MD, DNB (Nephrology)
Dr. Rajasekara Chakravarthi graduated from Mysore University (MBBS) in 1993 and completed MD (internal medicine) from the same university in 1996. Subsequently he trained as a fellow in Nephrology under the guidance of Dr.M.K.Mani between June 1997 to June 1999. He successfully completed the national board of examinations (Nephrology) DNB-NBE India. He worked as a Consultant Nephrologist at JSS medical college and hospitals Mysore between Aug 1999 to Oct 2000 and then as a Consultant Nephrologist at Apollo hospitals Chennai between Oct 2000 to March 2002. He shifted to the city of Hyderabad in March 2002 and started the department of Nephrology at CARE hospitals, the institute of medical sciences. He was the Head of the department of Nephrology CARE hospitals Banjara hills from March 2002 to September 2011. Since September 2011 till Sep 2015 he officiated as the Director Nephrology services CARE group of hospitals India which is a 16 hospitals group spread across the country. Since Sep 2015 till date he is the director of Nephrology services STAR hospitals, Hyderabad. India.
He has keen interest in understanding Acute Kidney Injury and is a member of the AKIN and ADQI (2011, Dublin) (2016, Asiago). He is appointed as faculty of the KDIGO working group on AKI - 2019. He has more than 75 publications in various national and international journals and more than 160 presentations in various conferences. He was a visiting and adjunct faculty to National Institute of Nutrition Hyderabad and JSS University Mysore. He is an organizing committee member and invited faculty for the international CRRT conference held at San Diego yearly since 2005 till date. He is a reviewer for the Indian Journal of nephrology, the official journal of the Indian society of Nephrology, Indian Heart Journal, Journal of Indian College of cardiology, Indian journal of Transplantation and Nephrology and Indian journal of Hypertension. He is presently nominated as a member AKI-committee of the International society of Nephrology. In the year 2016 he has organized and co-chaired the 17th ADQI held at Hyderabad India on Management of AKI in the developing world. He has been organizing AKI and CRRT conferences and works shops since 2004 . He has been part of the active transplantation programme since 1997 at Apollo Hospitals - Chennai, JSS Medical College Hospital - Mysore, Care Group of Hospitals - India and presently at STAR Hospitals - Hyderabad, being part of more than 650 transplantations so far both live related and cadaveric.
He is the founding trustee of the NGO, Care For Your Kidney Foundation (cfykf) started in the year 2015 with the aim of creating awareness in the public regarding kidney disease and preventing kidney disease in the community. So far the foundation has completed more than five thousand screening in the urban slums of Hyderabad. The foundation also subsidizes dialysis and kidney transplants for the needy population of the country.
He is the founding director of Renown clinical services which is a group offering Nephrology services presently to six hospitals in the city of Hyderabad. An Annual meeting on AKI (acute kidney injury) and CRRT is conducted by Renown associates since 2016 namely Selections from Sandiego. This meeting provides training in all modalities of RRT (dialysis) in ICU and brings the highlights of the AKI and CRRT meeting held annually in Sandiego by CRRT Inc. and UCSD. This meeting held at Sandiego annually is into its 25th year.
11:30-12:30
Update from Ongoing and Late Breaking Trials
(12 minutes each)
1. Lessons learned from STARRT-AKI - Wald
2. Renal Effects of the Beta-HCG Derivative EA-230 in Cardiac Surgery Patients - Pickkers
3. ARDS Trials: An Update - Liu
4. Long Term Outcomes of AKI: Lessons from the ARID Study - Selby
5. Biomarkers for Renal Recovery: An Update of the RUBY Trial - Hoste
Room: Coronado Ballroom
Eric Hoste, MD, PhD
Eric HOSTE
Training
- Doctor in Medicine, Surgery, and Obstetrics, Ghent University, Belgium 1989.
- Board Certified: Internal Medicine, October 1995.
- Board Certified: Intensive Care Medicine 1997.
- PhD Doctorate in the Medical Sciences, 30th November 2004 titled Acute Renal Failure in Critically Ill Patients.
Working career
- Chief of Clinic, Intensive Care Unit, Ghent University Hospital, Belgium
- Research fellow in Critical Care Medicine, The CRISMA laboratory, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, August-December 2003
Author and co-author of
- 42 publications in international peer reviewed journals
- 5 book chapters
Kathleen Liu, MD, PhD, MAS
Kathleen D. Liu, MD, PhD, MAS is a Professor in the Departments of Medicine and Anesthesia, Divisions of Nephrology and Critical Care Medicine at the University of California, San Francisco. Dr. Liu graduated from the University of California, San Francisco and trained as a resident at the Brigham and Womens Hospital in Boston. She trained in nephrology and critical care at the University of California, San Francisco. She is board-certified in both nephrology and critical care. Her research interests include biomarkers of kidney disease, acute kidney injury and acute lung injury.
Peter Pickkers, MD, PhD
Peter Pickkers is an internist-intensivist and professor of Experimental Intensive Care Medicine. His research focuses on modulation of the innate immune response, sepsis and specific organ dysfunction, among which the kidney.
Nick Selby, MD
Dr Selby studied medicine at the University of Nottingham, graduating in 1998, and after completing post-graduate training in the East Midlands was appointed a full-time NHS consultant nephrologist at the Royal Derby Hospital in 2009. In 2015 he was appointed Associate Professor of Nephrology at the University of Nottingham, based in the Centre for Kidney Research and Innovation (www.nottingham.ac.uk/research/groups/renal), Royal Derby Hospital Postgraduate Medical School.
Dr. Selby is a clinical academic with primary interests in Acute Kidney Injury (AKI), Magnetic Resonance Imaging (MRI) of the kidney and the haemodynamic consequences of dialysis. He led the development of one of the first e-alert systems for AKI in the UK and is CI on several investigator-instigated studies in these areas. Since 2011 Dr Selby has been awarded peer reviewed grant funding from MRC, the Health Foundation, Kidney Research UK and British Renal Society. He has published over 60 peer-reviewed articles. Dr Selby has several national AKI roles, including leadership of the AKI Clinical Study Group that sits within the UK Kidney Research Consortium, the co-chair of the UK Renal Imaging Network and programme board of the NHS England ‘Think Kidneys’ programme.
Ron Wald, MD
Ron Wald is a nephrologist at St. Michael's Hospital in Toronto where he also serves as the Medical Director of the hospital's Hemodialysis Program. He is an Associate Professor of Medicine at the University of Toronto. His primary research interest is in critical care nephrology and he has been involved in several clinical trials in this area. He is currently co-leading an international randomized controlled trial on the timing of renal replacement therapy in acute kidney injury. Ron's other interests are volume optimization in patients with AKI and the post-discharge care provided to AKI survivors.
12:30-12:55
Critical Care Nephrology: Literature Review
Room: Coronado Ballroom
Noel Gibney, MB FRCP(C)
Current Position:
Professor, Department of Critical Care Medicine,Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Medical School:
University College Dublin, Ireland
Internal Medicine/Nephrology:
St. Vincents Hospital, Dublin, Ireland
Pulmonary Medicine:
University of Alberta, Edmonton, AB, Canada
Critical Care Medicine:
Harvard University, Cambridge, MA, USA
Interests:
CRRT, Sepsis, Information Technology
12:55-1:00
Closing Remarks
Room: Coronado Ballroom
Ravindra Mehta, MBBS, MD, DM, FACP
Dr. Mehta is Professor of Medicine in the Division of Nephrology and Associate Chair for Clinical Affairs in the Department of Medicine at the University of California, San Diego (UCSD) where he directs the Clinical nephrology and dialysis programs. He is also the Chair of the International Society of Nephrology Commission on Acute Renal Failure, founding member of the Acute Dialysis Quality Initiative. He received the M.B.B.S. degree (1976) from the Government Medical School in Amritsar, India, and the M.D. (1979) and D.M. (1981) degrees from the Post Graduate Institute of Medical Education and Research in Chandigarh, India. He subsequently completed a nephrology fellowship at the University of Rochester in Rochester New York and obtained his boards in internal medicine (1986) and Nephrology (1988). He has been on the faculty at San Diego since 1988. His reserach interests are in the field of acute renal failure and he has directed several clinical studies in the management of patients with ARF including comparing different dialytic modalities, conducting large multicenter observational studies of ARF with the PICARD group, evaluating different predictive models for outcomes in ARF, investigating the role of cytokine removal by dialysis membranes in sepsis and ARF, and evaluating techniques for determining the amount of excess fluid in dialysis patients.
1:00
Conference Adjourns
Room: Coronado Ballroom
